Affiliation: Makerere University
- Comparative detection of trypanosomal DNA by loop-mediated isothermal amplification and PCR from flinders technology associates cards spotted with patient bloodEnock Matovu
Department of Veterinary Parasitology and Microbiology, Faculty of Veterinary Medicine, Makerere University, P O Box 7062, Kampala, Uganda
J Clin Microbiol 48:2087-90. 2010..LAMP may be useful to monitor emerging HAT foci or to test travelers returning from countries where HAT is endemic. It should be evaluated in a case-control study to determine its utility as a HAT diagnostic...
- Landmarks in the evolution of technologies for identifying trypanosomes in tsetse fliesJohn C Enyaru
Department of Biochemistry, Makerere University, P O Box 7062, Kampala, Uganda
Trends Parasitol 26:388-94. 2010..Over this period, methods for detecting and identifying trypanosomes have evolved through various landmark discoveries. This review describes the evolution of methods for identifying African trypanosomes in their tsetse fly vectors...
- Towards Point-of-Care Diagnostic and Staging Tools for Human African TrypanosomiaisisEnock Matovu
School of Veterinary Medicine, Makerere University, P O Box 7062, Kampala, Uganda
J Trop Med 2012:340538. 2012..In this paper, we review the available diagnostics and explore recent advances towards development of novel point-of-care diagnostic tests...
- Phase II evaluation of sensitivity and specificity of PCR and NASBA followed by oligochromatography for diagnosis of human African trypanosomiasis in clinical samples from D.R. Congo and UgandaEnock Matovu
Department of Veterinary Parasitology and Microbiology, Makerere University, Kampala, Uganda
PLoS Negl Trop Dis 4:e737. 2010..In this study we evaluate the sensitivity and specificity of the PCR-OC and NASBA-OC for diagnosis of Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense human African trypanosomiasis (HAT)...
- Interleukin (IL)-6 and IL-10 Are Up Regulated in Late Stage Trypanosoma brucei rhodesiense Sleeping SicknessCharles D Kato
School of Bio security, Biotechnical and Laboratory Sciences, College of Veterinary Medicine, Animal Resources and Bio security, Makerere University, Kampala, Uganda
PLoS Negl Trop Dis 9:e0003835. 2015..We hypothesized that disease progression and severity of the neurological response is modulated by cytokines...