Mustafa Ark

Summary

Affiliation: Mersin University
Country: Turkey

Publications

  1. ncbi request reprint Effects of HA-1077 and Y-27632, two rho-kinase inhibitors, in the human umbilical artery
    Mustafa Ark
    Department of Pharmacology, Mersin University, Faculty of Medicine, Mersin, Turkey
    Cell Biochem Biophys 41:331-42. 2004
  2. ncbi request reprint Rho-associated protein kinase II (rock II) expression in normal and preeclamptic human placentas
    M Ark
    Department of Pharmacology, Mersin University, Faculty of Medicine, Campus Yenisehir, 33169 Mersin, Turkey
    Placenta 26:81-4. 2005
  3. ncbi request reprint Involvement of rho kinase in the ouabain-induced contractions of the rat renal arteries
    Mustafa Ark
    Department of Pharmacology, Mersin University, Faculty of Medicine, Turkey
    Biochem Biophys Res Commun 340:417-21. 2006
  4. pmc Expression of Rho-kinase and its functional role in the contractile activity of the mouse vas deferens
    Kansu Buyukafsar
    Department of Pharmacology, Medical Faculty, Mersin University, Campus Yenisehir, Mersin 33169, Turkey
    Br J Pharmacol 140:743-9. 2003
  5. ncbi request reprint Rho-kinase expression and its contribution to the control of perfusion pressure in the isolated rat mesenteric vascular bed
    Kansu Buyukafsar
    Department of Pharmacology, Medical Faculty Mersin University, Campus Yenişehir 33169, Mersin, Turkey
    Eur J Pharmacol 485:263-8. 2004
  6. doi request reprint Nitric oxide does not downregulate Rho-kinase (ROCK-2) expression in rat coronary endothelial cells
    R Nalan Tiftik
    Department of Pharmacology, Medical Faculty, Mersin University, Campus Yenisehir, Mersin, Turkey
    J Cardiovasc Pharmacol 51:140-7. 2008
  7. doi request reprint Ouabain-induced apoptosis and Rho kinase: a novel caspase-2 cleavage site and fragment of Rock-2
    Mustafa Ark
    Faculty of Pharmacy, Department of Pharmacology, Gazi University, Etiler, 06330 Ankara, Turkey
    Apoptosis 15:1494-506. 2010
  8. ncbi request reprint Upregulation of Rho-kinase (ROCK-2) expression and enhanced contraction to endothelin-1 in the mesenteric artery from lipopolysaccharide-treated rats
    Kansu Buyukafsar
    Department of Pharmacology Medical Faculty Mersin University Campus Yenişehir 33169 Mersin, Turkey
    Eur J Pharmacol 498:211-7. 2004
  9. doi request reprint Chronic ouabain treatment induces Rho kinase activation
    Aysun Ozdemir
    Department of Pharmacology, Faculty of Pharmacy, Gazi University, Ankara, Turkey
    Arch Pharm Res 38:1897-905. 2015
  10. doi request reprint Chemical preconditioning effect of 3-nitropropionic acid in anesthetized rat heart
    Nilufer Nermin Turan
    University of Gazi, Faculty of Pharmacy, Department of Pharmacology, Ankara, Turkey
    Life Sci 82:928-33. 2008

Collaborators

  • Kansu Buyukafsar
  • Belgin Polat
  • Ismail Un
  • Ayşe Erol
  • Nilufer N Turan
  • Aysun Ozdemir
  • Fatoş İlkay Alp Yildirim
  • Eda Aypar
  • Ozge Tuğçe Paşaoğlu
  • R Nalan Tiftik
  • Osman Ozdemir
  • Döne Bülbül
  • Yaprak Dilber Şimay
  • Biljana Yaren
  • Deniz Kaleli Durman
  • Burçin İbişoğlu
  • Birsel Sönmez Uydeş Doğan
  • Gürkan Gözübüyük
  • Ayşegül Demirtaş
  • Gürkan Şahan
  • Halil Yaman
  • Nurten Turkozkan
  • Mehmet Agilli
  • Mehtap G Cnar
  • Havva Kubat
  • Sibel Ulker

Detail Information

Publications14

  1. ncbi request reprint Effects of HA-1077 and Y-27632, two rho-kinase inhibitors, in the human umbilical artery
    Mustafa Ark
    Department of Pharmacology, Mersin University, Faculty of Medicine, Mersin, Turkey
    Cell Biochem Biophys 41:331-42. 2004
    ..However, this effect appears to be limited to intracellular calcium-induced contractions and may be more important in sustaining contractions rather than the initial phase of force development...
  2. ncbi request reprint Rho-associated protein kinase II (rock II) expression in normal and preeclamptic human placentas
    M Ark
    Department of Pharmacology, Mersin University, Faculty of Medicine, Campus Yenisehir, 33169 Mersin, Turkey
    Placenta 26:81-4. 2005
    ..However, it is considered that rock II expression may also increase to compensate for placental functions changing in preeclampsia...
  3. ncbi request reprint Involvement of rho kinase in the ouabain-induced contractions of the rat renal arteries
    Mustafa Ark
    Department of Pharmacology, Mersin University, Faculty of Medicine, Turkey
    Biochem Biophys Res Commun 340:417-21. 2006
    ..This mechanism may be important in essential hypertension with elevated endogenous ouabain levels...
  4. pmc Expression of Rho-kinase and its functional role in the contractile activity of the mouse vas deferens
    Kansu Buyukafsar
    Department of Pharmacology, Medical Faculty, Mersin University, Campus Yenisehir, Mersin 33169, Turkey
    Br J Pharmacol 140:743-9. 2003
    ....
  5. ncbi request reprint Rho-kinase expression and its contribution to the control of perfusion pressure in the isolated rat mesenteric vascular bed
    Kansu Buyukafsar
    Department of Pharmacology, Medical Faculty Mersin University, Campus Yenişehir 33169, Mersin, Turkey
    Eur J Pharmacol 485:263-8. 2004
    ....
  6. doi request reprint Nitric oxide does not downregulate Rho-kinase (ROCK-2) expression in rat coronary endothelial cells
    R Nalan Tiftik
    Department of Pharmacology, Medical Faculty, Mersin University, Campus Yenisehir, Mersin, Turkey
    J Cardiovasc Pharmacol 51:140-7. 2008
    ....
  7. doi request reprint Ouabain-induced apoptosis and Rho kinase: a novel caspase-2 cleavage site and fragment of Rock-2
    Mustafa Ark
    Faculty of Pharmacy, Department of Pharmacology, Gazi University, Etiler, 06330 Ankara, Turkey
    Apoptosis 15:1494-506. 2010
    ..Our data indicate that ouabain induces both Rock-1 and Rock-2 cleavage via caspase-dependent mechanisms and provide evidence that Rocks are involved in ouabain-induced cell-to-cell detachment and apoptosis...
  8. ncbi request reprint Upregulation of Rho-kinase (ROCK-2) expression and enhanced contraction to endothelin-1 in the mesenteric artery from lipopolysaccharide-treated rats
    Kansu Buyukafsar
    Department of Pharmacology Medical Faculty Mersin University Campus Yenişehir 33169 Mersin, Turkey
    Eur J Pharmacol 498:211-7. 2004
    ....
  9. doi request reprint Chronic ouabain treatment induces Rho kinase activation
    Aysun Ozdemir
    Department of Pharmacology, Faculty of Pharmacy, Gazi University, Ankara, Turkey
    Arch Pharm Res 38:1897-905. 2015
    ..Our current data present the first evidence that Rho kinase is involved in the development of ouabain-induced hypertension in rats...
  10. doi request reprint Chemical preconditioning effect of 3-nitropropionic acid in anesthetized rat heart
    Nilufer Nermin Turan
    University of Gazi, Faculty of Pharmacy, Department of Pharmacology, Ankara, Turkey
    Life Sci 82:928-33. 2008
    ..Protective effect is associated with via decreased production of bax protein expression...
  11. ncbi request reprint Mediation of nitric oxide from photosensitive stores in the photorelaxation of the rabbit corpus cavernosum
    Kansu Buyukafsar
    Department of Pharmacology, Medical Faculty, Mersin University, Campus Yenisehir, 33169, Mersin, Turkey
    Eur J Pharmacol 459:263-7. 2003
    ..Based on these findings, the substance, which mediates photorelaxation, could be NO released from putative stores in the rabbit corpus cavernosum, and L-NA as well as NaNO(2) but not 3-NT produce NO under the influence of UV light...
  12. doi request reprint Cardiac glycoside-induced cell death and Rho/Rho kinase pathway: Implication of different regulation in cancer cell lines
    Aysun Ozdemir
    Department of Pharmacology, Gazi University, Faculty of Pharmacy, 06330, Turkey
    Steroids 109:29-43. 2016
    ..In conclusion, these findings indicate that the Rho/ROCK pathway is regulated differently in cancer cell lines compared to normal cells during cardiac glycosides-induced cell death. ..
  13. doi request reprint Atorvastatin acutely reduces the reactivity to spasmogens in rat aorta: implication of the inhibition of geranylgeranylation and MYPT-1 phosphorylation
    Fatoş İlkay Alp Yildirim
    Department of Pharmacology, Faculty of Pharmacy, Istanbul University, 34116, Beyazit, Istanbul, Turkey
    Fundam Clin Pharmacol 30:96-106. 2016
    ....
  14. doi request reprint The effect of taurine on the relationship between NO, ADMA and homocysteine in endotoxin-mediated inflammation in HUVEC cultures
    Ozge Tuğçe Paşaoğlu
    Department of Medical Biochemistry, Faculty of Medicine, Gazi University, Ankara, Turkey
    Inflammation 37:1439-43. 2014
    ..Hcy levels increased significantly compared to taurine group (p<0.05) and did not change compared to LPS group. Taurine was effective on ADMA-NO relationship whereas no beneficial effect was observed in Hcy levels (p<0.05)...