Sean N Tucker

Summary

Publications

  1. doi request reprint Oral adenoviral-based vaccines: historical perspective and future opportunity
    Sean N Tucker
    Vaxart, Inc, 600 Townsend St, Suite 120E, San Francisco, CA 94103, USA
    Expert Rev Vaccines 7:25-31. 2008
  2. doi request reprint Oral administration of an adenovirus vector encoding both an avian influenza A hemagglutinin and a TLR3 ligand induces antigen specific granzyme B and IFN-γ T cell responses in humans
    Wendy Peters
    Vaxart, Inc, 20 California Street, San Francisco, CA 94111, United States
    Vaccine 31:1752-8. 2013
  3. pmc An adenovirus-based vaccine with a double-stranded RNA adjuvant protects mice and ferrets against H5N1 avian influenza in oral delivery models
    Ciaran D Scallan
    Vaxart, Inc, San Francisco, CA, USA
    Clin Vaccine Immunol 20:85-94. 2013
  4. pmc Oral Modeling of an Adenovirus-Based Quadrivalent Influenza Vaccine in Ferrets and Mice
    Ciaran D Scallan
    Vaxart, Inc, South San Francisco, CA, USA
    Infect Dis Ther . 2016
  5. ncbi request reprint Systemic and mucosal antibody responses following retroductal gene transfer to the salivary gland
    Sean N Tucker
    Genteric, Inc, 1650 Harbor Bay Parkway, Alameda, California 94502, USA
    Mol Ther 8:392-9. 2003

Collaborators

  • Ciaran D Scallan
  • Jonathan D Lindbloom
  • Debora W Tingley
  • Wendy Peters
  • Martin L Kabongo
  • James S Toomey
  • Jennifer R Brandl
  • C Josefina Martinez
  • George R Trager

Detail Information

Publications5

  1. doi request reprint Oral adenoviral-based vaccines: historical perspective and future opportunity
    Sean N Tucker
    Vaxart, Inc, 600 Townsend St, Suite 120E, San Francisco, CA 94103, USA
    Expert Rev Vaccines 7:25-31. 2008
    ..Recent discoveries may allow this platform approach to reach the clinic within a few years...
  2. doi request reprint Oral administration of an adenovirus vector encoding both an avian influenza A hemagglutinin and a TLR3 ligand induces antigen specific granzyme B and IFN-γ T cell responses in humans
    Wendy Peters
    Vaxart, Inc, 20 California Street, San Francisco, CA 94111, United States
    Vaccine 31:1752-8. 2013
    ..To test the safety and immunogenicity of an orally delivered avian influenza vaccine. The vaccine has a non-replicating adenovirus type 5 vector backbone which expresses hemagglutinin from avian influenza and a TLR3 ligand as an adjuvant...
  3. pmc An adenovirus-based vaccine with a double-stranded RNA adjuvant protects mice and ferrets against H5N1 avian influenza in oral delivery models
    Ciaran D Scallan
    Vaxart, Inc, San Francisco, CA, USA
    Clin Vaccine Immunol 20:85-94. 2013
    ..Similarly, experiments in mice demonstrated selective immune responses against HA with peroral delivery and the ability to circumvent preexisting vector immunity...
  4. pmc Oral Modeling of an Adenovirus-Based Quadrivalent Influenza Vaccine in Ferrets and Mice
    Ciaran D Scallan
    Vaxart, Inc, South San Francisco, CA, USA
    Infect Dis Ther . 2016
    ..These studies have evaluated monovalent vaccines to date. To protect against the major circulating A and B influenza strains, a multivalent influenza vaccine will be required...
  5. ncbi request reprint Systemic and mucosal antibody responses following retroductal gene transfer to the salivary gland
    Sean N Tucker
    Genteric, Inc, 1650 Harbor Bay Parkway, Alameda, California 94502, USA
    Mol Ther 8:392-9. 2003
    ..These data suggest that SG genetic immunization may offer advantages over conventional routes of vaccination...