Małgorzata Trocha

Summary

Publications

  1. ncbi request reprint Influence of ezetimibe on ADMA-DDAH-NO pathway in rat liver subjected to partial ischemia followed by global reperfusion
    Małgorzata Trocha
    Department of Pharmacology, Wroclaw Medical University and 4th Military Hospital in Wroclaw, Mikulicza Radeckiego 2, PL 50 345 Wrocław, Poland
    Pharmacol Rep 65:122-33. 2013
  2. ncbi request reprint Effect of simvastatin on nitric oxide synthases (eNOS, iNOS) and arginine and its derivatives (ADMA, SDMA) in ischemia/reperfusion injury in rat liver
    Małgorzata Trocha
    Department of Pharmacology, Wroclaw Medical University, Mikulicza Radeckiego 2, PL 50 345 Wrocław, Poland
    Pharmacol Rep 62:343-51. 2010
  3. ncbi request reprint Effect of simvastatin treatment on rat livers subjected to ischemia/reperfusion
    Małgorzata Trocha
    Department of Pharmacology, Wroclaw Medical University, Mikulicza Radeckiego 2, PL 50 345 Wrocław, Poland
    Pharmacol Rep 62:757-62. 2010
  4. ncbi request reprint Effect of quercetin-5'-sulfonic acid sodium salt on SOD activity and ADMA/DDAH pathway in extracorporeal liver perfusion in rats
    Małgorzata Trocha
    Department of Pharmacology, Wroclaw Medical University, Poland
    Adv Clin Exp Med 21:423-31. 2012
  5. ncbi request reprint Effect of cyclophosphamide and morin-5'-sulfonic acid sodium salt, alone or in combination, on ADMA/DDAH pathway in rats
    Anna Merwid-Lad
    Department of Pharmacology, Wroclaw Medical University, Mikulicza Radeckiego 2, PL 50 345 Wrocław, Poland
    Pharmacol Rep 65:201-7. 2013
  6. doi request reprint Impact of morin-5'-sulfonic acid sodium salt on cyclophosphamide-induced gastrointestinal toxicity in rats
    Anna Merwid-Lad
    Department of Pharmacology, Wroclaw Medical University, Wrocław, Poland Electronic address
    Pharmacol Rep 67:1259-63. 2015
  7. ncbi request reprint The impact of morin, a natural flavonoid, on cyclophosphamide-induced changes in the oxidative stress parameters in rat livers
    Anna Merwid-Lad
    Department of Pharmacology, Wroclaw Medical University, Poland
    Adv Clin Exp Med 23:505-9. 2014
  8. doi request reprint Age-related changes in ADMA-DDAH-NO pathway in rat liver subjected to partial ischemia followed by global reperfusion
    Małgorzata Trocha
    Department of Pharmacology, Wrocław Medical University, Mikulicza Radeckiego 2, PL 50 345 Wrocław, Poland
    Exp Gerontol 50:45-51. 2014
  9. ncbi request reprint Influence of nifedipine, nitrendipine and verapamil at low concentration on antipyrine metabolism examined by extracorporeal rat liver perfusion
    Adam Szelag
    Department of Pharmacology, Medical University of Wrocław, Mikulicza Radeckiego 2, PL 50 345 Wrocław, Poland
    Pol J Pharmacol 55:203-8. 2003
  10. ncbi request reprint Effect of aging process on liver function in extracorporeal rat liver perfusion
    Małgorzata Trocha
    Department of Pharmacology, Wrocław Medical University, Wrocław, Poland
    Hepatogastroenterology 54:1207-11. 2007

Collaborators

  • Jan Magdalan
  • Ewa Chlebda
  • Piotr Dziegiel
  • A Merwid-Lad
  • Adam Szelag
  • Tomasz Sozanski
  • Marta Karaźniewicz-Łada
  • Wojciech Słupski
  • Dorota Ksiądzyna
  • Antoni Szumny
  • Grzegorz Kiełbowicz
  • Małgorzata Pieśniewska
  • Małgorzata Rzepka
  • Lidia Fereniec
  • Maria Rutkowska
  • Wojciech Dziewiszek

Detail Information

Publications13

  1. ncbi request reprint Influence of ezetimibe on ADMA-DDAH-NO pathway in rat liver subjected to partial ischemia followed by global reperfusion
    Małgorzata Trocha
    Department of Pharmacology, Wroclaw Medical University and 4th Military Hospital in Wroclaw, Mikulicza Radeckiego 2, PL 50 345 Wrocław, Poland
    Pharmacol Rep 65:122-33. 2013
    ..We evaluated effect of ezetimibe on selected parameters determining NO level in rat liver subjected to ischemia reperfusion (IR)...
  2. ncbi request reprint Effect of simvastatin on nitric oxide synthases (eNOS, iNOS) and arginine and its derivatives (ADMA, SDMA) in ischemia/reperfusion injury in rat liver
    Małgorzata Trocha
    Department of Pharmacology, Wroclaw Medical University, Mikulicza Radeckiego 2, PL 50 345 Wrocław, Poland
    Pharmacol Rep 62:343-51. 2010
    ..SV had no effect on ADMA concentration under normal and pathological conditions...
  3. ncbi request reprint Effect of simvastatin treatment on rat livers subjected to ischemia/reperfusion
    Małgorzata Trocha
    Department of Pharmacology, Wroclaw Medical University, Mikulicza Radeckiego 2, PL 50 345 Wrocław, Poland
    Pharmacol Rep 62:757-62. 2010
    ..SV did not evoke any noticeable protective changes in rat livers after 3 weeks of treatment. After I/R, some of the observed properties could suggest that SV may have even made liver function and the oxidative state worse...
  4. ncbi request reprint Effect of quercetin-5'-sulfonic acid sodium salt on SOD activity and ADMA/DDAH pathway in extracorporeal liver perfusion in rats
    Małgorzata Trocha
    Department of Pharmacology, Wroclaw Medical University, Poland
    Adv Clin Exp Med 21:423-31. 2012
    ..Quercetin-5'-sulfonic acid sodium salt (NaQSA) exerts good aqueous solubility, strong antioxidant activity and low toxicity...
  5. ncbi request reprint Effect of cyclophosphamide and morin-5'-sulfonic acid sodium salt, alone or in combination, on ADMA/DDAH pathway in rats
    Anna Merwid-Lad
    Department of Pharmacology, Wroclaw Medical University, Mikulicza Radeckiego 2, PL 50 345 Wrocław, Poland
    Pharmacol Rep 65:201-7. 2013
    ....
  6. doi request reprint Impact of morin-5'-sulfonic acid sodium salt on cyclophosphamide-induced gastrointestinal toxicity in rats
    Anna Merwid-Lad
    Department of Pharmacology, Wroclaw Medical University, Wrocław, Poland Electronic address
    Pharmacol Rep 67:1259-63. 2015
    ..The aim of this study was to evaluate the effect of morin-5'-sulfonic acid sodium salt (NaMSA) on cyclophosphamide-induced gastrointestinal changes in rats...
  7. ncbi request reprint The impact of morin, a natural flavonoid, on cyclophosphamide-induced changes in the oxidative stress parameters in rat livers
    Anna Merwid-Lad
    Department of Pharmacology, Wroclaw Medical University, Poland
    Adv Clin Exp Med 23:505-9. 2014
    ..Cyclophosphamide (CPX) has many adverse effects, partly due to oxidative stress induction in various tissues. Morin is one of the natural flavonoids with strong antioxidant properties...
  8. doi request reprint Age-related changes in ADMA-DDAH-NO pathway in rat liver subjected to partial ischemia followed by global reperfusion
    Małgorzata Trocha
    Department of Pharmacology, Wrocław Medical University, Mikulicza Radeckiego 2, PL 50 345 Wrocław, Poland
    Exp Gerontol 50:45-51. 2014
    ..Liver function is affected during ischemia/reperfusion (IR). We evaluated the effect of the aging process on selected parameters determining the NO level in rat liver subjected to IR...
  9. ncbi request reprint Influence of nifedipine, nitrendipine and verapamil at low concentration on antipyrine metabolism examined by extracorporeal rat liver perfusion
    Adam Szelag
    Department of Pharmacology, Medical University of Wrocław, Mikulicza Radeckiego 2, PL 50 345 Wrocław, Poland
    Pol J Pharmacol 55:203-8. 2003
    ..The present experiment suggests that low concentrations of CCI can exert hepatoprotective effect. However, confirmation of this conclusion requires further studies using other experimental methods...
  10. ncbi request reprint Effect of aging process on liver function in extracorporeal rat liver perfusion
    Małgorzata Trocha
    Department of Pharmacology, Wrocław Medical University, Wrocław, Poland
    Hepatogastroenterology 54:1207-11. 2007
    ..However, the current state of knowledge about liver aging processes is incomplete. In this study, using extracorporeal liver perfusion model, we evaluated the differences between liver function in young and old rats...
  11. doi request reprint Influence of water-soluble flavonoids, quercetin-5'-sulfonic acid sodium salt and morin-5'-sulfonic acid sodium salt, on antioxidant parameters in the subacute cadmium intoxication mouse model
    Ewa Chlebda
    Department of Pharmacology, Wroclaw Medical University, Mikulicza Radeckiego 2, PL 50 345 Wroclaw, Poland
    Exp Toxicol Pathol 62:105-8. 2010
    ..NaQSA and NaMSA significantly counteracted cadmium-induced decreases in SOD and GSH levels. No significant differences in SOD and GSH levels between groups exposed to cadmium receiving NaQSA or/and NaMSA were observed...
  12. ncbi request reprint Omeprazole does not change the oral bioavailability or pharmacokinetics of vinpocetine in rats
    Tomasz Sozanski
    Department of Pharmacology, Wroclaw Medical University, Mikulicza Radeckiego 2, PL 50 345 Wrocław, Poland
    Pharmacol Rep 63:1258-63. 2011
    ..The mean T(max) in both regimens was estimated for 1.5 h. There were no statistically significant differences between both regimens. In conclusion, omeprazole did not affect the pharmacokinetic profile of vinpocetine...
  13. ncbi request reprint The role of calcium and calcium channel blocking drugs in damage to the liver preserved for transplantation
    Małgorzata Trocha
    Department and Chair of Pharmacology, Wroclaw Medical University, Poland
    Ann Transplant 9:5-11. 2004
    ..But in some experiments CCB do not modify calcium concentration. More research on preservation conditions is needed to increase the probability of a successful liver transplantation...