Mike P Wattjes

Summary

Affiliation: VU University Medical Center
Country: The Netherlands

Publications

  1. pdf No association of abnormal cranial venous drainage with multiple sclerosis: a magnetic resonance venography and flow-quantification study
    Mike P Wattjes
    MS Center Amsterdam, Department of Radiology, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
    J Neurol Neurosurg Psychiatry 82:429-35. 2011
  2. doi request reprint Structural MRI
    Mike P Wattjes
    Alzheimer Center Amsterdam, Department of Radiology, VU University Medical Center, Amsterdam, The Netherlands
    Int Psychogeriatr 23:S13-24. 2011
  3. doi request reprint MRI in the Diagnosis and Monitoring of Multiple Sclerosis: An Update
    M P Wattjes
    MS Center and Department of Radiology and Nuclear Medicine, VU University Medical Centre, De Boelelaan 1117, 1081 HV, Amsterdam, Netherlands
    Clin Neuroradiol 25:157-65. 2015
  4. doi request reprint Diagnosis of asymptomatic natalizumab-associated PML: are we between a rock and a hard place?
    Mike P Wattjes
    Department of Radiology, MS Center Amsterdam, Nuclear Medicine and PET Research, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands
    J Neurol 261:1139-43. 2014
  5. pmc Diagnostic relevance of high field MRI in clinical neuroradiology: the advantages and challenges of driving a sports car
    Mike P Wattjes
    Department of Radiology, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands
    Eur Radiol 22:2304-6. 2012
  6. pmc Neuromuscular imaging in inherited muscle diseases
    Mike P Wattjes
    Department of Radiology, VU University Medical Center, De Boelelaan 1117, 1081, HV, Amsterdam, The Netherlands
    Eur Radiol 20:2447-60. 2010
  7. doi request reprint ["Chronic cerebrospinal venous insufficiency" in multiple sclerosis - is multiple sclerosis a disease of the cerebrospinal venous outflow system?]
    M P Wattjes
    MS Center Amsterdam, Department of Radiology, VU University Medical Center, Amsterdam, The Netherlands
    Rofo 183:523-30. 2011
  8. doi request reprint Diagnostic imaging of patients in a memory clinic: comparison of MR imaging and 64-detector row CT
    Mike P Wattjes
    Department of Radiology, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
    Radiology 253:174-83. 2009
  9. doi request reprint High field MRI in the diagnosis of multiple sclerosis: high field-high yield?
    Mike P Wattjes
    MS Center Amsterdam, Department of Radiology, VU University Medical Center, Amsterdam, The Netherlands
    Neuroradiology 51:279-92. 2009
  10. doi request reprint Does high field MRI allow an earlier diagnosis of multiple sclerosis?
    Mike P Wattjes
    Dept of Radiology Neuroradiology, University of Bonn, Bonn, Germany
    J Neurol 255:1159-63. 2008

Detail Information

Publications73

  1. pdf No association of abnormal cranial venous drainage with multiple sclerosis: a magnetic resonance venography and flow-quantification study
    Mike P Wattjes
    MS Center Amsterdam, Department of Radiology, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
    J Neurol Neurosurg Psychiatry 82:429-35. 2011
    ..This study aimed to investigate the intracranial and extracranial venous anatomy and the intracerebral venous flow profile in patients with MS and healthy controls using magnetic resonance venography (MRV)...
  2. doi request reprint Structural MRI
    Mike P Wattjes
    Alzheimer Center Amsterdam, Department of Radiology, VU University Medical Center, Amsterdam, The Netherlands
    Int Psychogeriatr 23:S13-24. 2011
    ..This review paper aims to give an overview of the application of structural MRI in the diagnostic procedure for memory clinic patients in terms of excluding and supporting the diagnosis of various diseases associated with dementia...
  3. doi request reprint MRI in the Diagnosis and Monitoring of Multiple Sclerosis: An Update
    M P Wattjes
    MS Center and Department of Radiology and Nuclear Medicine, VU University Medical Centre, De Boelelaan 1117, 1081 HV, Amsterdam, Netherlands
    Clin Neuroradiol 25:157-65. 2015
    ..This review article aims to give an update on the role of MRI in the diagnosis and monitoring of MS with particular emphasis to treatment efficacy and safety, both in clinical practice and in research. ..
  4. doi request reprint Diagnosis of asymptomatic natalizumab-associated PML: are we between a rock and a hard place?
    Mike P Wattjes
    Department of Radiology, MS Center Amsterdam, Nuclear Medicine and PET Research, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands
    J Neurol 261:1139-43. 2014
    ....
  5. pmc Diagnostic relevance of high field MRI in clinical neuroradiology: the advantages and challenges of driving a sports car
    Mike P Wattjes
    Department of Radiology, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands
    Eur Radiol 22:2304-6. 2012
    ..5 T MRI. These findings are highly relevant since a new generation of high field MRI systems operating at 7 T has recently been introduced...
  6. pmc Neuromuscular imaging in inherited muscle diseases
    Mike P Wattjes
    Department of Radiology, VU University Medical Center, De Boelelaan 1117, 1081, HV, Amsterdam, The Netherlands
    Eur Radiol 20:2447-60. 2010
    ..We also provide diagnostic algorithms that might guide us through the differential diagnosis in hereditary myopathies...
  7. doi request reprint ["Chronic cerebrospinal venous insufficiency" in multiple sclerosis - is multiple sclerosis a disease of the cerebrospinal venous outflow system?]
    M P Wattjes
    MS Center Amsterdam, Department of Radiology, VU University Medical Center, Amsterdam, The Netherlands
    Rofo 183:523-30. 2011
    ..In conclusion, the present conclusive data confuting the theory of CCSVI in MS should lead to reluctance with respect to the interventional treatment of possible venous anomalies in MS patients...
  8. doi request reprint Diagnostic imaging of patients in a memory clinic: comparison of MR imaging and 64-detector row CT
    Mike P Wattjes
    Department of Radiology, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
    Radiology 253:174-83. 2009
    ....
  9. doi request reprint High field MRI in the diagnosis of multiple sclerosis: high field-high yield?
    Mike P Wattjes
    MS Center Amsterdam, Department of Radiology, VU University Medical Center, Amsterdam, The Netherlands
    Neuroradiology 51:279-92. 2009
    ..The objectives of this article are to review the current knowledge and level of evidence concerning the application of high field MRI in MS and to give some ideas of research perspectives in the future...
  10. doi request reprint Does high field MRI allow an earlier diagnosis of multiple sclerosis?
    Mike P Wattjes
    Dept of Radiology Neuroradiology, University of Bonn, Bonn, Germany
    J Neurol 255:1159-63. 2008
    ....
  11. ncbi request reprint Prognostic value of high-field proton magnetic resonance spectroscopy in patients presenting with clinically isolated syndromes suggestive of multiple sclerosis
    Mike P Wattjes
    Department of Radiology Neuroradiology, University of Bonn, Bonn, Germany
    Neuroradiology 50:123-9. 2008
    ....
  12. ncbi request reprint Axonal damage but no increased glial cell activity in the normal-appearing white matter of patients with clinically isolated syndromes suggestive of multiple sclerosis using high-field magnetic resonance spectroscopy
    M P Wattjes
    Department of Radiology Neuroradiology, University of Bonn, Bonn, Germany
    AJNR Am J Neuroradiol 28:1517-22. 2007
    ..The purpose of this study was to investigate metabolic alterations in NAWM in patients with CIS with use of high-field (1)H-MR spectroscopy and to compare the results to those in patients with an early course of MS...
  13. ncbi request reprint High field MR imaging and 1H-MR spectroscopy in clinically isolated syndromes suggestive of multiple sclerosis: correlation between metabolic alterations and diagnostic MR imaging criteria
    Mike P Wattjes
    Dept of Radiology Neuroradiology, University of Bonn, Germany
    J Neurol 255:56-63. 2008
    ....
  14. doi request reprint Clinical application of multi-contrast 7-T MR imaging in multiple sclerosis: increased lesion detection compared to 3 T confined to grey matter
    Wolter L de Graaf
    Department of Radiology, VU University Medical Center, P O Box 7057, 1007 MB, Amsterdam, The Netherlands
    Eur Radiol 23:528-40. 2013
    ..However, a clinical MRI protocol at 7 T has never been investigated. We evaluated the clinical value of 7-T MRI by investigating the sensitivity of lesion detection compared with 3 T...
  15. doi request reprint Diagnostic performance of brain MRI in pharmacovigilance of natalizumab-treated MS patients
    Mike P Wattjes
    Department of Radiology and Nuclear Medicine, MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
    Mult Scler 22:1174-83. 2016
    ..In natalizumab-treated multiple sclerosis (MS) patients, magnetic resonance imaging (MRI) is considered as a sensitive tool in detecting both MS disease activity and progressive multifocal leukoencephalopathy (PML)...
  16. doi request reprint Diagnostic Accuracy of the Frontotemporal Dementia Consensus Criteria in the Late-Onset Frontal Lobe Syndrome
    Everard G B Vijverberg
    Alzheimer Centre and Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam, The Netherlands
    Dement Geriatr Cogn Disord 41:210-9. 2016
    ..We aimed to prospectively assess the diagnostic accuracy of the revised criteria for behavioural variant frontotemporal dementia (bvFTD) among subjects presenting with a frontal lobe syndrome in middle-late adulthood...
  17. pmc Cerebral perfusion in the predementia stages of Alzheimer's disease
    Maja A A Binnewijzend
    Department of Radiology and Nuclear Medicine, Neuroscience Campus Amsterdam, Alzheimercenter Amsterdam, VU University Medical Center, P O Box 7057, 1007 MB, Amsterdam, The Netherlands
    Eur Radiol 26:506-14. 2016
    ..To investigate arterial spin-labelling (ASL) cerebral blood flow (CBF) changes in predementia stages of Alzheimer's disease (AD)...
  18. doi request reprint White matter hyperintensities and cognitive impairment during electroconvulsive therapy in severely depressed elderly patients
    Mardien L Oudega
    Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands EMGO Institute for Health and Care Research and VU University Medical Centre and GGZ in Geest, Amsterdam, The Netherlands Electronic address
    Am J Geriatr Psychiatry 22:157-66. 2014
    ..We hypothesized that both white matter hyperintensities and medial temporal lobe atrophy contribute to transient cognitive impairment during ECT...
  19. pmc Improved in vivo detection of cortical lesions in multiple sclerosis using double inversion recovery MR imaging at 3 Tesla
    Birgit Simon
    Department of Radiology, University Hospital of Bonn, Bonn, Germany
    Eur Radiol 20:1675-83. 2010
    ..To investigate the impact of a higher magnetic field strength of 3 Tesla (T) on the detection rate of cortical lesions in multiple sclerosis (MS) patients, in particular using a dedicated double inversion recovery (DIR) pulse sequence...
  20. doi request reprint Spinal cord lesions in patients with clinically isolated syndrome: a powerful tool in diagnosis and prognosis
    Madeleine H Sombekke
    Department of Neurology, MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
    Neurology 80:69-75. 2013
    ..Our aim was to analyze the contribution of SC involvement in clinically isolated syndrome (CIS) in diagnosing MS according the McDonald 2010 criteria and in predicting conversion to clinically definite MS (CDMS)...
  21. ncbi request reprint Higher sensitivity in the detection of inflammatory brain lesions in patients with clinically isolated syndromes suggestive of multiple sclerosis using high field MRI: an intraindividual comparison of 1.5 T with 3.0 T
    Mike P Wattjes
    Department of Radiology, University of Bonn, Sigmund Freud Strasse 25, 53105, Bonn, Germany
    Eur Radiol 16:2067-73. 2006
    ..01; p=0.01). In conclusion, high-field MRI at 3.0 T provides a significantly higher detection rate of inflammatory brain lesions especially in the infratentorial, juxtacortical and periventricular anatomic region...
  22. doi request reprint MRI characteristics of early PML-IRIS after natalizumab treatment in patients with MS
    Mike P Wattjes
    MS Center Amsterdam, VU University Medical Center, Amsterdam, the Netherlands Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands
    J Neurol Neurosurg Psychiatry 87:879-84. 2016
    ....
  23. doi request reprint Multi-parametric structural magnetic resonance imaging in relation to cognitive dysfunction in long-standing multiple sclerosis
    Marita Daams
    Department of Radiology and Nuclear Medicine, Neuroscience Campus Amsterdam, VU University Medical Centre, The Netherlands Department of Anatomy and Neurosciences, Neuroscience Campus Amsterdam, VU University Medical Centre, The Netherlands
    Mult Scler 22:608-19. 2016
    ..Most previous studies investigating the imaging substrate of cognitive deficits in multiple sclerosis included patients with relatively short disease durations and were limited to one modality/brain region...
  24. doi request reprint Morphological features of MS lesions on FLAIR* at 7 T and their relation to patient characteristics
    Iris D Kilsdonk
    Department of Radiology, VU University Medical Center, De Boelelaan 1118, 1081 HZ, Amsterdam, The Netherlands
    J Neurol 261:1356-64. 2014
    ..In addition, our study shows that these phenomena do not show a relation to patient's clinical characteristics and cannot be allocated to certain MS disease subtypes. ..
  25. doi request reprint The structure of the geriatric depressed brain and response to electroconvulsive therapy
    Mardien L Oudega
    Department of Psychiatry, VU University Medical Center, Amsterdam, the Netherlands Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands Department of Anatomy and Neurosciences, VU University Medical Center, Amsterdam, The Netherlands Electronic address
    Psychiatry Res 222:1-9. 2014
    ..These results are possibly explained by the connectivity between these brain regions and an interconnected network that is particularly activated by the ECT-induced seizures. ..
  26. doi request reprint Cerebral blood flow measured with 3D pseudocontinuous arterial spin-labeling MR imaging in Alzheimer disease and mild cognitive impairment: a marker for disease severity
    Maja A A Binnewijzend
    Department of Radiology, VU University Medical Center, PO Box 7057, 1007 MB Amsterdam, The Netherlands
    Radiology 267:221-30. 2013
    ..0 t...
  27. pmc Lesion detection at seven Tesla in multiple sclerosis using magnetisation prepared 3D-FLAIR and 3D-DIR
    Wolter L de Graaf
    Department of Radiology, VU University Medical Center Amsterdam, De Boelelaan 1117, NL 1081 HV, Amsterdam, The Netherlands
    Eur Radiol 22:221-31. 2012
    ..To examine the feasibility and value of 7 T 3D T2-weighted Fluid Attenuated Inversion Recovery (FLAIR) and Double Inversion Recovery (DIR) MR sequences for lesion detection in multiple sclerosis (MS)...
  28. doi request reprint Contribution of white matter hyperintensities, medial temporal lobe atrophy and cortical atrophy on outcome, seven to twelve years after ECT in severely depressed geriatric patients
    Mardien L Oudega
    GGZ inGeest Department of Psychiatry, VU University Medical Center, Amsterdam, the Netherlands Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands Department of Anatomy and Neurosciences, VU University Medical Center, Amsterdam, The Netherlands
    J Affect Disord 185:144-8. 2015
    ..The aim of the study was to investigate the effects of structural abnormalities in the brain on cognitive decline, dementia and survival...
  29. doi request reprint Distinct perfusion patterns in Alzheimer's disease, frontotemporal dementia and dementia with Lewy bodies
    Maja A A Binnewijzend
    Department of Radiology and Nuclear Medicine, VU University Medical Center and Neuroscience Campus Amsterdam, P O Box 7057, 1007 MB, Amsterdam, The Netherlands
    Eur Radiol 24:2326-33. 2014
    ....
  30. ncbi request reprint Imaging of inflammatory lesions at 3.0 Tesla in patients with clinically isolated syndromes suggestive of multiple sclerosis: a comparison of fluid-attenuated inversion recovery with T2 turbo spin-echo
    Mike P Wattjes
    Department of Radiology, University of Bonn, Sigmund Freud Strasse 25, 53105, Bonn, Germany
    Eur Radiol 16:1494-500. 2006
    ..In conclusion, FLAIR provides the highest sensitivity when compared with the T2 TSE, although T2 TSE still has a diagnostic relevance in terms of MRI criteria classification...
  31. doi request reprint Improved differentiation between MS and vascular brain lesions using FLAIR* at 7 Tesla
    Iris D Kilsdonk
    Department of Radiology, VU University Medical Center, De Boelelaan 1118, 1081, hz, Amsterdam, The Netherlands
    Eur Radiol 24:841-9. 2014
    ..To investigate whether a new magnetic resonance image (MRI) technique called T2*-weighted fluid attenuation inversion recovery (FLAIR*) can differentiate between multiple sclerosis (MS) and vascular brain lesions, at 7 Tesla (T)...
  32. doi request reprint Heterogeneous Language Profiles in Patients with Primary Progressive Aphasia due to Alzheimer's Disease
    Eva Louwersheimer
    Alzheimer Center and Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
    J Alzheimers Dis 51:581-90. 2016
    ..The logopenic variant of Primary Progressive Aphasia (lvPPA) is associated with underlying Alzheimer's disease (AD) pathology and characterized by impaired single word retrieval and repetition of phrases and sentences...
  33. doi request reprint The identification of cognitive subtypes in Alzheimer's disease dementia using latent class analysis
    Nienke M E Scheltens
    Department of Neurology, Alzheimer Center, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
    J Neurol Neurosurg Psychiatry 87:235-43. 2016
    ..In addition, we explored the relationship between the identified cognitive subtypes, and their demographical and neurobiological characteristics...
  34. pmc Cerebral perfusion and glucose metabolism in Alzheimer's disease and frontotemporal dementia: two sides of the same coin?
    Sander C J Verfaillie
    Department of Radiology and Nuclear Medicine, VU University Medical Centre, Amsterdam, The Netherlands
    Eur Radiol 25:3050-9. 2015
    ..Since cerebral blood flow (CBF) is related to glucose metabolism, our aim was to investigate the extent of overlap of abnormalities between AD and FTD...
  35. doi request reprint MRI pattern in asymptomatic natalizumab-associated PML
    Mike P Wattjes
    Department of Radiology and Nuclear Medicine, MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
    J Neurol Neurosurg Psychiatry 86:793-8. 2015
    ..To investigate the MRI manifestation pattern of asymptomatic natalizumab-associated progressive multifocal leukoencephalopathy (PML) in patients with multiple sclerosis (MS)...
  36. doi request reprint Unraveling the neuroimaging predictors for motor dysfunction in long-standing multiple sclerosis
    Marita Daams
    From the Departments of Radiology and Nuclear Medicine M D, M D S, M P W, F B, Anatomy and Neurosciences M D, J J G G, Neurology B M J U, P K T, L J B, J K, and Physics and Medical Technology P J W P, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
    Neurology 85:248-55. 2015
    ..To find the strongest neuroimaging predictors for motor dysfunction using conventional and quantitative imaging measures focusing on the corticospinal tract (CST) in a large cohort of patients with long-standing multiple sclerosis (MS)...
  37. doi request reprint Improved detection of active multiple sclerosis lesions: 3D subtraction imaging
    Bastiaan Moraal
    Department of Radiology, MS Center Amsterdam, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
    Radiology 255:154-63. 2010
    ....
  38. doi request reprint Shifting imaging targets in multiple sclerosis: from inflammation to neurodegeneration
    René M Vigeveno
    VU University Medical Center, Department of Radiology, Amsterdam, The Netherlands
    J Magn Reson Imaging 36:1-19. 2012
    ....
  39. doi request reprint Increased cortical grey matter lesion detection in multiple sclerosis with 7 T MRI: a post-mortem verification study
    Iris D Kilsdonk
    Department of Radiology and Nuclear Medicine, VU University Medical Centre, Amsterdam, The Netherlands
    Brain 139:1472-81. 2016
    ..Unfortunately, (subpial) cortical pathology remains more extensive than 7 T magnetic resonance imaging can reveal. ..
  40. doi request reprint MRI criteria differentiating asymptomatic PML from new MS lesions during natalizumab pharmacovigilance
    Martijn T Wijburg
    Department of Neurology, Amsterdam Neuroscience, VUmc MS Center Amsterdam, VU University Medical Center, Amsterdam, the Netherlands Department of Radiology and Nuclear Medicine, Amsterdam Neuroscience, VUmc MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
    J Neurol Neurosurg Psychiatry 87:1138-45. 2016
    ..We aim to define MRI characteristics that can aid in this differentiation...
  41. doi request reprint Regional atrophy is associated with impairment in distinct cognitive domains in Alzheimer's disease
    Lieke L Smits
    Alzheimer Center and Department of Neurology, VU University Medical Center, Amsterdam, The Netherlands Electronic address
    Alzheimers Dement 10:S299-305. 2014
    ..We evaluated whether occurrence of posterior atrophy (PA) and medial temporal lobe atrophy (MTA) could account for differences in cognitive domains affected...
  42. doi request reprint Associations between cerebral small-vessel disease and Alzheimer disease pathology as measured by cerebrospinal fluid biomarkers
    Maartje I Kester
    Alzheimer Center, Department of Neurology, VU University Medical Center, Amsterdam, The Netherlands
    JAMA Neurol 71:855-62. 2014
    ..It remains unclear if and how associations between cerebral small-vessel disease and Alzheimer disease (AD) pathology lead to cognitive decline and dementia...
  43. doi request reprint The chameleon of neuroinflammation: magnetic resonance imaging characteristics of natalizumab-associated progressive multifocal leukoencephalopathy
    Mike P Wattjes
    Department of Radiology, Nuclear Medicine and PET Research, University Medical Center, The Netherlands
    Mult Scler 19:1826-40. 2013
    ..Finally, we present guidelines to differentiate MRI findings in PML from inflammatory demyelinating lesions, to facilitate the early diagnosis of PML in patients treated with natalizumab. ..
  44. doi request reprint Prevalence of cortical superficial siderosis in a memory clinic population
    Hazel I Zonneveld
    From the Alzheimer Center and the Neuroscience Campus Amsterdam, and Departments of Radiology and Nuclear Medicine H I Z, M P W, F B, Neurology J D C G, N D P, P S, W M v d F, Epidemiology and Biostatistics W M v d F, Physics and Medical Technology J P A K, and Internal Medicine M M, VU University Medical Center, Amsterdam, The Netherlands
    Neurology 82:698-704. 2014
    ....
  45. doi request reprint Quantitative regional validation of the visual rating scale for posterior cortical atrophy
    Christiane Möller
    Alzheimer Center and Department of Neurology, VU University Medical Center, Neuroscience Campus Amsterdam, P O Box 7057, 1007 MB, Amsterdam, The Netherlands
    Eur Radiol 24:397-404. 2014
    ..Validate the four-point visual rating scale for posterior cortical atrophy (PCA) on magnetic resonance images (MRI) through quantitative grey matter (GM) volumetry and voxel-based morphometry (VBM) to justify its use in clinical practice...
  46. pmc Visual assessment of posterior atrophy development of a MRI rating scale
    Esther L G E Koedam
    Department of Neurology and Alzheimer Centre, VU University Medical Centre, PO Box 7057, 1007 MB, Amsterdam, The Netherlands
    Eur Radiol 21:2618-25. 2011
    ..To develop a visual rating scale for posterior atrophy (PA) assessment and to analyse whether this scale aids in the discrimination between Alzheimer's disease (AD) and other dementias...
  47. doi request reprint White matter hyperintensities, medial temporal lobe atrophy, cortical atrophy, and response to electroconvulsive therapy in severely depressed elderly patients
    Mardien L Oudega
    Department of Psychiatry and Stichting Buitenamstel Geestgronden, VU University Medical Centre, AJ Ernststraat 887, 1081 HL Amsterdam, The Netherlands
    J Clin Psychiatry 72:104-12. 2011
    ..The respective value of these factors in response prediction is unclear...
  48. doi request reprint Matrix Metalloproteinases in Alzheimer's Disease and Concurrent Cerebral Microbleeds
    Flora H Duits
    Alzheimer Center and Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
    J Alzheimers Dis 48:711-20. 2015
    ..Lower levels of TIMPs in AD patients with microbleeds suggest less MMP inhibition in patients with concurrent cerebral microbleeds, which may hypothetically lead to a more vulnerable blood-brain barrier in these patients...
  49. doi request reprint Angiotensin-converting enzyme in cerebrospinal fluid and risk of brain atrophy
    Hadassa M Jochemsen
    Alzheimer Center and Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    J Alzheimers Dis 44:153-62. 2015
    ..Yet, it may also decrease this risk, as it functions to degrade amyloid-β, thereby reducing brain atrophy...
  50. doi request reprint Inflammation high-field magnetic resonance imaging
    Iris D Kilsdonk
    Department of Radiology, VU University Medical Center, PO Box 7057, 1007 MB Amsterdam, The Netherlands
    Neuroimaging Clin N Am 22:135-57, ix. 2012
    ..This article reviews the value of high-field MR imaging in examining inflammatory MS abnormalities. Furthermore, possibilities and challenges for the future of high-field MR imaging in MS are discussed...
  51. doi request reprint Pluriformity of inflammation in multiple sclerosis shown by ultra-small iron oxide particle enhancement
    Machteld M Vellinga
    Department of Neurology, University Medical Centre, Amsterdam, The Netherlands
    Brain 131:800-7. 2008
    ..The use of USPIO-enhanced MRI is likely to lead to more insight in the pluriformity of inflammation in multiple sclerosis...
  52. pmc Preparing children with a mock scanner training protocol results in high quality structural and functional MRI scans
    Henrica M A de Bie
    Department of Pediatrics, Pediatric Endocrinology, VU University Medical Center, PO Box 7057, 1007 MB, Amsterdam, The Netherlands
    Eur J Pediatr 169:1079-85. 2010
    ..It may reduce the need for sedation in young children undergoing MRI. Our protocol is also effective in preparing young children to participate in fMRI investigations...
  53. doi request reprint Clinical relevance of improved microbleed detection by susceptibility-weighted magnetic resonance imaging
    Jeroen D C Goos
    Department of Neurology and Alzheimer Center, Vrije Universiteit Medical Center, P O Box 7057, 1007 MB Amsterdam, The Netherlands
    Stroke 42:1894-900. 2011
    ..We sought to determine whether associations of MBs with clinical characteristics, risk factors, white-matter hyperintensities, and lacunes were different on GRE versus SWI in memory clinic patients...
  54. doi request reprint Consensus recommendations for MS cortical lesion scoring using double inversion recovery MRI
    J J G Geurts
    VU University Medical Center, Department of Anatomy and Neuroscience, MF G 116, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands
    Neurology 76:418-24. 2011
    ..This study aimed to formulate consensus recommendations for scoring cortical lesions in patients with MS, using DIR images acquired in 6 European centers according to local protocols...
  55. doi request reprint Diagnostic Accuracy of MRI and Additional [18F]FDG-PET for Behavioral Variant Frontotemporal Dementia in Patients with Late Onset Behavioral Changes
    Everard G B Vijverberg
    Alzheimer Centre and Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Centre, Amsterdam, The Netherlands
    J Alzheimers Dis 53:1287-97. 2016
    ....
  56. doi request reprint Elevated CSF neurofilament proteins predict brain atrophy: A 15-year follow-up study
    Axel Petzold
    Department of Neurology and Ophthalmology, VUmc MS Center Amsterdam, VU University Medical Center, Neuroscience Campus, Amsterdam, The Netherlands Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK
    Mult Scler 22:1154-62. 2016
    ..Body fluid and structural imaging biomarkers give information on neurodegeneration. The relationship over time is not known in multiple sclerosis...
  57. doi request reprint Molecular imaging in the diagnosis of Alzheimer's disease: visual assessment of [11C]PIB and [18F]FDDNP PET images
    Nelleke Tolboom
    Department of Nuclear Medicine and PET Research, VU University Medical Centre, Amsterdam, The Netherlands
    J Neurol Neurosurg Psychiatry 81:882-4. 2010
    ..To evaluate visual assessment of [(11)C]PIB and [(18)F]FDDNP PET images as potential supportive diagnostic markers for Alzheimer's disease (AD)...
  58. doi request reprint Natalizumab-associated progressive multifocal leukoencephalopathy is not preceded by elevated drug concentrations
    Zoé LE van Kempen
    Department of Neurology, Neuroscience Campus Amsterdam, VUmc MS Center Amsterdam, VU University Medical Center Amsterdam, Amsterdam, The Netherlands
    Mult Scler . 2016
    ..This idea is based on the hypothesis that high drug concentrations increase the risk of PML...
  59. doi request reprint Validation of an MRI Rating Scale for Amyloid-Related Imaging Abnormalities
    Arianne Bechten
    Image Analysis Centre, Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands
    J Neuroimaging . 2017
    ..Recently, a magnetic resonance imaging (MRI) rating scale was developed for ARIA-E detection and classification. The aim of this study was to validate the use of this rating scale in a larger patient group with multiple raters...
  60. pmc Concomitant granule cell neuronopathy in patients with natalizumab-associated PML
    Martijn T Wijburg
    Department of Neurology, MS Center Amsterdam, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands
    J Neurol 263:649-56. 2016
    ..Three cases with imaging findings suggestive of GCN were detected among 44 natalizumab-associated PML patients. GCN may, therefore, be more common than previously considered in natalizumab-associated PML patients...
  61. doi request reprint Heterogeneous imaging characteristics of JC virus granule cell neuronopathy (GCN): a case series and review of the literature
    Martijn T Wijburg
    Department of Radiology and Nuclear Medicine, MS Center Amsterdam, VU University Medical Center, De Boelelaan 117, 1081 HV, Amsterdam, The Netherlands
    J Neurol 262:65-73. 2015
    ..This suggests an overlap of GCN with other JCV-related diseases, such as progressive multifocal leukoencephalopathy. ..
  62. doi request reprint Fatal B-cell lymphoma following chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids
    Hjalmar J De Graaff
    Department of Neurology, VU University Medical Center, Amsterdam, The Netherlands
    JAMA Neurol 70:915-8. 2013
    ..We report on a well-documented patient who presented with clinical, radiological, and pathological characteristics of CLIPPERS and who had an unfavorable outcome...
  63. ncbi request reprint Different early pathogenesis in myotilinopathy compared to primary desminopathy
    Dirk Fischer
    Muskellabor, Department of Neurology, University of Bonn, Bonn, Germany
    Neuromuscul Disord 16:361-7. 2006
    ..These findings suggest that unrelated molecular pathways may result in seemingly similar disease phenotypes at late disease stages...
  64. pmc The Holy Grail in diagnostic neuroradiology: 3T or 3D?
    Frederik Barkhof
    Eur Radiol 21:449-56. 2011
    ....
  65. doi request reprint Recent developments in muscle imaging of neuromuscular disorders
    Dirk Fischer
    aDivision of Neuropaediatrics, University Children s Hospital Basel bDepartment of Neurology, University Hospital Basel, Basel, Switzerland cDepartment of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands
    Curr Opin Neurol 29:614-20. 2016
    ..In this update, we describe recent findings on imaging techniques used for the analysis and quantification of affected muscles, advances in pattern recognition, and quantitative muscle imaging in clinical studies...
  66. doi request reprint Haemostatic and cranial computed tomography characteristics in patients with acute and delayed coagulopathy after isolated traumatic brain injury
    Gaby Franschman
    Department of Anesthesiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands
    Brain Inj 26:1464-71. 2012
    ..To investigate whether the development of coagulopathy at different stages after isolated traumatic brain injury (TBI) is associated with distinct cranial computed tomography characteristics...
  67. doi request reprint The investigation of acute optic neuritis: a review and proposed protocol
    Axel Petzold
    Departments of Neurology and Ophthalmology, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, Netherlands
    Nat Rev Neurol 10:447-58. 2014
    ..In this article, we review the literature and attempt to formulate a consensus for the investigation of patients with acute optic neuritis, both in standard care and in research with relevance to clinical treatment trials. ..
  68. doi request reprint Diagnosis of natalizumab-associated progressive multifocal leukoencephalopathy using MRI
    Mike P Wattjes
    Department of Radiology and Nuclear Medicine, MS Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
    Curr Opin Neurol 27:260-70. 2014
    ..This review describe the role and advancements of MRI in the diagnosis and monitoring of progressive multifocal leukoencephalopathy (PML) in multiple sclerosis patients treated with natalizumab...
  69. ncbi request reprint Atelectasis in children undergoing either propofol infusion or positive pressure ventilation anesthesia for magnetic resonance imaging
    Goetz Lutterbey
    Department of Radiology, University of Bonn, Bonn, Germany
    Paediatr Anaesth 17:121-5. 2007
    ..Atelectasis because of anesthesia is a recognized problem but may be affected by the anesthetic technique. We compared magnetic resonance images of atelectasis in children undergoing two types of anesthesia...
  70. ncbi request reprint Does high-field MR imaging have an influence on the classification of patients with clinically isolated syndromes according to current diagnostic mr imaging criteria for multiple sclerosis?
    M P Wattjes
    Department of Radiology Neuroradiology, University Hospital of Bonn, Bonn, Germany
    AJNR Am J Neuroradiol 27:1794-8. 2006
    ....
  71. ncbi request reprint Double inversion recovery brain imaging at 3T: diagnostic value in the detection of multiple sclerosis lesions
    M P Wattjes
    Department of Radiology, University of Bonn, Bonn, Germany
    AJNR Am J Neuroradiol 28:54-9. 2007
    ..To prospectively determine the sensitivity in the detection of multiple sclerosis (MS) lesions by using double inversion recovery (DIR), fluid-attenuated inversion recovery (FLAIR), and T2-weighted turbo spin-echo (T2 TSE) MR imaging at 3T...
  72. ncbi request reprint Clinical evaluation of a speed optimized T2 weighted fast spin echo sequence at 3.0 T using variable flip angle refocusing, half-Fourier acquisition and parallel imaging
    G Lutterbey
    Department of Radiology, University of Bonn, Sigmund Freud Strasse 25, 53105 Bonn, Germany
    Br J Radiol 80:668-73. 2007
    ..FAS-TSE provides sufficient T2-SE contrast and diagnostic image quality for whole brain studies in 11 s. It is suited to reduce motion artefacts in restless patients and for fast acquisition of additional scanning planes...
  73. ncbi request reprint MR imaging of the prostate at 3.0T with external phased array coil - preliminary results
    N Morakkabati-Spitz
    Department of Radiology, University of Bonn, Bonn, Germany
    Eur J Med Res 13:287-91. 2008
    ..0T enables to image the prostate without endorectal coil. Aim of this study was to evaluate the diagnostic accuracy of phased array coil 3.0T MRI in patients with suspicion of prostate cancer...