Nynke E Hahn

Summary

Affiliation: VU University Medical Center
Country: The Netherlands

Publications

  1. doi request reprint NOX5 expression is increased in intramyocardial blood vessels and cardiomyocytes after acute myocardial infarction in humans
    Nynke E Hahn
    Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
    Am J Pathol 180:2222-9. 2012
  2. doi request reprint NOX2, p22phox and p47phox are targeted to the nuclear pore complex in ischemic cardiomyocytes colocalizing with local reactive oxygen species
    Nynke E Hahn
    Department of Pathology, VU University Medical Centre, De Boelelaan 1117, Amsterdam, The Netherlands
    Cell Physiol Biochem 27:471-8. 2011
  3. doi request reprint Homocysteine-induced cardiomyocyte apoptosis and plasma membrane flip-flop are independent of S-adenosylhomocysteine: a crucial role for nuclear p47(phox)
    Jessica A Sipkens
    Department of Pathology, VU University Medical Center, De Boelelaan 1117, 1007 MB Amsterdam, The Netherlands
    Mol Cell Biochem 358:229-39. 2011
  4. doi request reprint S-Adenosylhomocysteine induces apoptosis and phosphatidylserine exposure in endothelial cells independent of homocysteine
    Jessica A Sipkens
    Department of Pathology, VU University Medical Centre, Amsterdam, The Netherlands
    Atherosclerosis 221:48-54. 2012
  5. pmc Early NADPH oxidase-2 activation is crucial in phenylephrine-induced hypertrophy of H9c2 cells
    Nynke E Hahn
    Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands ICaR VU, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands
    Cell Signal 26:1818-24. 2014
  6. pmc Loss of DPP4 activity is related to a prothrombogenic status of endothelial cells: implications for the coronary microvasculature of myocardial infarction patients
    Paul A J Krijnen
    Department of Pathology, VU University Medical Center, De Boelelaan 1117, 1007 MB, Amsterdam, The Netherlands
    Basic Res Cardiol 107:233. 2012
  7. doi request reprint Homocysteine induces phosphatidylserine exposure in cardiomyocytes through inhibition of Rho kinase and flippase activity
    Jessica A Sipkens
    Department of Pathology, VU University Medical Centre, Amsterdam, The Netherlands
    Cell Physiol Biochem 28:53-62. 2011
  8. doi request reprint Intravenous clusterin administration reduces myocardial infarct size in rats
    Annemieke van Dijk
    Department of Pathology, VU Medical Center, Amsterdam, The Netherlands
    Eur J Clin Invest 40:893-902. 2010

Detail Information

Publications8

  1. doi request reprint NOX5 expression is increased in intramyocardial blood vessels and cardiomyocytes after acute myocardial infarction in humans
    Nynke E Hahn
    Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
    Am J Pathol 180:2222-9. 2012
    ..For the first time to our knowledge, we demonstrate NOX5 expression in human intramyocardial blood vessels and cardiomyocytes, with significant increases in the affected myocardium after acute myocardial infarction...
  2. doi request reprint NOX2, p22phox and p47phox are targeted to the nuclear pore complex in ischemic cardiomyocytes colocalizing with local reactive oxygen species
    Nynke E Hahn
    Department of Pathology, VU University Medical Centre, De Boelelaan 1117, Amsterdam, The Netherlands
    Cell Physiol Biochem 27:471-8. 2011
    ..g. under ischemia or high concentrations of homocysteine, is an important step in the induction of apoptosis in these cells. Here this ischemia-induced nuclear targeting and activation of NOX2 was specified in cardiomyocytes...
  3. doi request reprint Homocysteine-induced cardiomyocyte apoptosis and plasma membrane flip-flop are independent of S-adenosylhomocysteine: a crucial role for nuclear p47(phox)
    Jessica A Sipkens
    Department of Pathology, VU University Medical Center, De Boelelaan 1117, 1007 MB Amsterdam, The Netherlands
    Mol Cell Biochem 358:229-39. 2011
    ....
  4. doi request reprint S-Adenosylhomocysteine induces apoptosis and phosphatidylserine exposure in endothelial cells independent of homocysteine
    Jessica A Sipkens
    Department of Pathology, VU University Medical Centre, Amsterdam, The Netherlands
    Atherosclerosis 221:48-54. 2012
    ....
  5. pmc Early NADPH oxidase-2 activation is crucial in phenylephrine-induced hypertrophy of H9c2 cells
    Nynke E Hahn
    Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands ICaR VU, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands
    Cell Signal 26:1818-24. 2014
    ..These data show that early NOX2-mediated ROS production is crucial in PE-induced hypertrophy of H9c2 cells...
  6. pmc Loss of DPP4 activity is related to a prothrombogenic status of endothelial cells: implications for the coronary microvasculature of myocardial infarction patients
    Paul A J Krijnen
    Department of Pathology, VU University Medical Center, De Boelelaan 1117, 1007 MB, Amsterdam, The Netherlands
    Basic Res Cardiol 107:233. 2012
    ..Our data suggest that the loss of DPP4 activity affects the anti-thrombogenic nature of the endothelium...
  7. doi request reprint Homocysteine induces phosphatidylserine exposure in cardiomyocytes through inhibition of Rho kinase and flippase activity
    Jessica A Sipkens
    Department of Pathology, VU University Medical Centre, Amsterdam, The Netherlands
    Cell Physiol Biochem 28:53-62. 2011
    ..In the present study the mechanism(s) involved in Hcy-induced PS exposure were analyzed...
  8. doi request reprint Intravenous clusterin administration reduces myocardial infarct size in rats
    Annemieke van Dijk
    Department of Pathology, VU Medical Center, Amsterdam, The Netherlands
    Eur J Clin Invest 40:893-902. 2010
    ..We therefore hypothesized that intravenous clusterin administration would reduce myocardial infarction damage...