Begona Diosdado

Summary

Affiliation: VU University Medical Center
Country: The Netherlands

Publications

  1. pmc Functional microRNA screening using a comprehensive lentiviral human microRNA expression library
    Jos B Poell
    Hubrecht Institute, Cancer Genomics Center, and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands
    BMC Genomics 12:546. 2011
  2. doi request reprint High-resolution array comparative genomic hybridization in sporadic and celiac disease-related small bowel adenocarcinomas
    Begona Diosdado
    Departments of Pathology and Gastroenterology, VU University Medical Center, Amsterdam, The Netherlands
    Clin Cancer Res 16:1391-401. 2010
  3. pmc A prognostic classifier for patients with colorectal cancer liver metastasis, based on AURKA, PTGS2 and MMP9
    Jeroen A C M Goos
    Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
    Oncotarget 7:2123-34. 2016
  4. pmc Methylation-mediated silencing and tumour suppressive function of hsa-miR-124 in cervical cancer
    Saskia M Wilting
    Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
    Mol Cancer 9:167. 2010
  5. pmc Oncogenic Role of miR-15a-3p in 13q Amplicon-Driven Colorectal Adenoma-to-Carcinoma Progression
    Florence L M de Groen
    Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
    PLoS ONE 10:e0132495. 2015
  6. doi request reprint Regulation of deoxycytidine kinase expression and sensitivity to gemcitabine by micro-RNA 330 and promoter methylation in cancer cells
    Jasmina Hodzic
    Department of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands
    Nucleosides Nucleotides Nucleic Acids 30:1214-22. 2011
  7. doi request reprint Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer
    Remco Nagel
    The Netherlands Cancer Institute, Division of Tumor Biology, Amsterdam, The Netherlands
    Cancer Res 68:5795-802. 2008
  8. doi request reprint Glucose Transporter 1 (SLC2A1) and Vascular Endothelial Growth Factor A (VEGFA) Predict Survival After Resection of Colorectal Cancer Liver Metastasis
    Jeroen A C M Goos
    Department of Pathology, VU University Medical Center, Amsterdam, the Netherlands Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands Department of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands
    Ann Surg 263:138-45. 2016
  9. pdf MLPAnalyzer: data analysis tool for reliable automated normalization of MLPA fragment data
    Jordy Coffa
    Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
    Cell Oncol 30:323-35. 2008

Collaborators

Detail Information

Publications9

  1. pmc Functional microRNA screening using a comprehensive lentiviral human microRNA expression library
    Jos B Poell
    Hubrecht Institute, Cancer Genomics Center, and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands
    BMC Genomics 12:546. 2011
    ..Dissecting the complexities of miRNA function continues to prove challenging as miRNAs are predicted to have thousands of targets, and mRNAs can be targeted by dozens of miRNAs...
  2. doi request reprint High-resolution array comparative genomic hybridization in sporadic and celiac disease-related small bowel adenocarcinomas
    Begona Diosdado
    Departments of Pathology and Gastroenterology, VU University Medical Center, Amsterdam, The Netherlands
    Clin Cancer Res 16:1391-401. 2010
    ..The molecular pathogenesis of small intestinal adenocarcinomas is not well understood. Understanding the molecular characteristics of small bowel adenocarcinoma may lead to more effective patient treatment...
  3. pmc A prognostic classifier for patients with colorectal cancer liver metastasis, based on AURKA, PTGS2 and MMP9
    Jeroen A C M Goos
    Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
    Oncotarget 7:2123-34. 2016
    ..Prognosis of patients with colorectal cancer liver metastasis (CRCLM) is estimated based on clinicopathological models. Stratifying patients based on tumor biology may have additional value...
  4. pmc Methylation-mediated silencing and tumour suppressive function of hsa-miR-124 in cervical cancer
    Saskia M Wilting
    Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
    Mol Cancer 9:167. 2010
    ..Since DNA methylation-based silencing of hsa-miR-124 occurs in various human cancers, we studied the frequency and functional effects of hsa-miR-124 methylation in cervical carcinogenesis...
  5. pmc Oncogenic Role of miR-15a-3p in 13q Amplicon-Driven Colorectal Adenoma-to-Carcinoma Progression
    Florence L M de Groen
    Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
    PLoS ONE 10:e0132495. 2015
    ..Taken together our findings suggest that miR-15a-3p may contribute to adenoma-to-carcinoma progression. ..
  6. doi request reprint Regulation of deoxycytidine kinase expression and sensitivity to gemcitabine by micro-RNA 330 and promoter methylation in cancer cells
    Jasmina Hodzic
    Department of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands
    Nucleosides Nucleotides Nucleic Acids 30:1214-22. 2011
    ..74), suggesting a role of miR-330 in post-transcriptional regulation of dCK. In conclusion, the 3' GC box and miR-330 may regulate dCK expression in cancer cells...
  7. doi request reprint Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer
    Remco Nagel
    The Netherlands Cancer Institute, Division of Tumor Biology, Amsterdam, The Netherlands
    Cancer Res 68:5795-802. 2008
    ..Thus, our results uncover a miRNA-mediated mechanism for the control of APC expression and Wnt pathway activity, and suggest its contribution to colorectal cancer pathogenesis...
  8. doi request reprint Glucose Transporter 1 (SLC2A1) and Vascular Endothelial Growth Factor A (VEGFA) Predict Survival After Resection of Colorectal Cancer Liver Metastasis
    Jeroen A C M Goos
    Department of Pathology, VU University Medical Center, Amsterdam, the Netherlands Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands Department of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands
    Ann Surg 263:138-45. 2016
    ..To investigate the individual and combined prognostic value of HIF1α, SLC2A1, and vascular endothelial growth factor A (VEGFA) in a multi-institutional cohort of patients with resected colorectal cancer liver metastasis (CRCLM)...
  9. pdf MLPAnalyzer: data analysis tool for reliable automated normalization of MLPA fragment data
    Jordy Coffa
    Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
    Cell Oncol 30:323-35. 2008
    ..We therefore set out to develop an MLPA data analysis strategy and tool that is simple to use, while still taking into account the above-mentioned sources of variation...