Christa Boer

Summary

Affiliation: Vrije Universiteit
Country: The Netherlands

Publications

  1. ncbi request reprint RhoA/Rho kinase and nitric oxide modulate the agonist-induced pulmonary artery diameter response time
    Christa Boer
    Laboratory for Physiology, Institute for Cardiovascular Research, Vrije Universiteit Medical Center, 1081 BT Amsterdam, The Netherlands
    Am J Physiol Heart Circ Physiol 282:H990-8. 2002
  2. ncbi request reprint The cardioprotective effect of sevoflurane depends on protein kinase C activation, opening of mitochondrial K(+)(ATP) channels, and the production of reactive oxygen species
    Wouter de Ruijter
    Department of Anesthesiology, Vrije Universiteit University Medical Center, Institute for Cardiovascular Research Vrije Universiteit, Amsterdam, The Netherlands
    Anesth Analg 97:1370-6. 2003
  3. ncbi request reprint Right-ventricular failure is associated with increased mitochondrial complex II activity and production of reactive oxygen species
    Everaldo M Redout
    Laboratory for Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands
    Cardiovasc Res 75:770-81. 2007
  4. ncbi request reprint Induced nitric oxide impairs relaxation but not contraction in endotoxin-exposed rat pulmonary arteries
    Christa Boer
    Laboratory for Physiology, VU University Medical Center, Amsterdam, The Netherlands
    J Surg Res 127:197-202. 2005
  5. ncbi request reprint Smooth muscle F-actin disassembly and RhoA/Rho-kinase signaling during endotoxin-induced alterations in pulmonary arterial compliance
    Christa Boer
    Laboratory for Physiology, Department of Anesthesiology, VU University Medical Center, Institute for Cardiovascular Research Vrije Universiteit, 1081 BT Amsterdam, The Netherlands
    Am J Physiol Lung Cell Mol Physiol 287:L649-55. 2004
  6. doi request reprint Right ventricular pacing improves right heart function in experimental pulmonary arterial hypertension: a study in the isolated heart
    M Louis Handoko
    Department of Physiology, VU University Medical Center, Institute for Cardiovascular Research, Amsterdam, The Netherlands
    Am J Physiol Heart Circ Physiol 297:H1752-9. 2009
  7. pmc The effect of perioperative insulin treatment on cardiodepression in mild adiposity in mice
    Chantal A Boly
    Department of Anesthesiology, Institute for Cardiovascular Research, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands
    Cardiovasc Diabetol 15:135. 2016
  8. doi request reprint Intraoperative cell salvage is associated with reduced postoperative blood loss and transfusion requirements in cardiac surgery: a cohort study
    Alexander B A Vonk
    Departments of Cardio Thoracic Surgery, Institute for Cardiovascular Research, Amsterdam, Netherlands Departments of Anesthesiology, Institute for Cardiovascular Research, Amsterdam, Netherlands Department of Epidemiology and Biostatistics, Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands
    Transfusion 53:2782-9. 2013
  9. doi request reprint Side-by-Side Alterations in Glycocalyx Thickness and Perfused Microvascular Density During Acute Microcirculatory Alterations in Cardiac Surgery
    Nick J Koning
    Department of Anesthesiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands
    Microcirculation 23:69-74. 2016
  10. doi request reprint Perioperative myocardial perfusion: an anesthesiologists' concern?
    Carolien S E Bulte
    Department of Anesthesiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands
    Curr Opin Anaesthesiol 28:101-6. 2015

Collaborators

Detail Information

Publications21

  1. ncbi request reprint RhoA/Rho kinase and nitric oxide modulate the agonist-induced pulmonary artery diameter response time
    Christa Boer
    Laboratory for Physiology, Institute for Cardiovascular Research, Vrije Universiteit Medical Center, 1081 BT Amsterdam, The Netherlands
    Am J Physiol Heart Circ Physiol 282:H990-8. 2002
    ..These effects were counteracted by Rho kinase inhibition. We show a role for RhoA/Rho kinase and NO in the modulation of pulmonary vascular reactivity...
  2. ncbi request reprint The cardioprotective effect of sevoflurane depends on protein kinase C activation, opening of mitochondrial K(+)(ATP) channels, and the production of reactive oxygen species
    Wouter de Ruijter
    Department of Anesthesiology, Vrije Universiteit University Medical Center, Institute for Cardiovascular Research Vrije Universiteit, Amsterdam, The Netherlands
    Anesth Analg 97:1370-6. 2003
    ..IMPLICATIONS: Protein kinase C, mitochondrial K(+)(ATP) channels and reactive oxygen species act within one downstream signaling pathway in mediating the cardioprotective effect of sevoflurane...
  3. ncbi request reprint Right-ventricular failure is associated with increased mitochondrial complex II activity and production of reactive oxygen species
    Everaldo M Redout
    Laboratory for Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands
    Cardiovasc Res 75:770-81. 2007
    ..Reactive oxygen species (ROS) have been implicated in the progression of ventricular hypertrophy to congestive heart failure. However, the source of increased oxidative stress in cardiomyocytes remains unclear...
  4. ncbi request reprint Induced nitric oxide impairs relaxation but not contraction in endotoxin-exposed rat pulmonary arteries
    Christa Boer
    Laboratory for Physiology, VU University Medical Center, Amsterdam, The Netherlands
    J Surg Res 127:197-202. 2005
    ..MATERIALS AND METHODS.: We investigated in endotoxin-exposed Wistar rat pulmonary arteries whether endogenous NO alters contractile and relaxing responses, by electrochemical NO and isometric force measurements...
  5. ncbi request reprint Smooth muscle F-actin disassembly and RhoA/Rho-kinase signaling during endotoxin-induced alterations in pulmonary arterial compliance
    Christa Boer
    Laboratory for Physiology, Department of Anesthesiology, VU University Medical Center, Institute for Cardiovascular Research Vrije Universiteit, 1081 BT Amsterdam, The Netherlands
    Am J Physiol Lung Cell Mol Physiol 287:L649-55. 2004
    ..They imply the involvement of F-actin rearrangement and RhoA/Rho-kinase signaling in endotoxemia-induced vascular lung injury...
  6. doi request reprint Right ventricular pacing improves right heart function in experimental pulmonary arterial hypertension: a study in the isolated heart
    M Louis Handoko
    Department of Physiology, VU University Medical Center, Institute for Cardiovascular Research, Amsterdam, The Netherlands
    Am J Physiol Heart Circ Physiol 297:H1752-9. 2009
    ..Taken together, we demonstrate that, in experimental PH, RV pacing improves RV function and diminishes adverse diastolic interaction. These findings provide a strong rationale for further in vivo explorations...
  7. pmc The effect of perioperative insulin treatment on cardiodepression in mild adiposity in mice
    Chantal A Boly
    Department of Anesthesiology, Institute for Cardiovascular Research, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands
    Cardiovasc Diabetol 15:135. 2016
    ....
  8. doi request reprint Intraoperative cell salvage is associated with reduced postoperative blood loss and transfusion requirements in cardiac surgery: a cohort study
    Alexander B A Vonk
    Departments of Cardio Thoracic Surgery, Institute for Cardiovascular Research, Amsterdam, Netherlands Departments of Anesthesiology, Institute for Cardiovascular Research, Amsterdam, Netherlands Department of Epidemiology and Biostatistics, Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands
    Transfusion 53:2782-9. 2013
    ....
  9. doi request reprint Side-by-Side Alterations in Glycocalyx Thickness and Perfused Microvascular Density During Acute Microcirculatory Alterations in Cardiac Surgery
    Nick J Koning
    Department of Anesthesiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands
    Microcirculation 23:69-74. 2016
    ..We investigated whether glycocalyx dimensions are reduced after onset of CPB and whether this is associated with alterations in microvascular perfusion...
  10. doi request reprint Perioperative myocardial perfusion: an anesthesiologists' concern?
    Carolien S E Bulte
    Department of Anesthesiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands
    Curr Opin Anaesthesiol 28:101-6. 2015
    ..The purpose of this review was to summarize the most recent findings on factors affecting myocardial perfusion in the perioperative period and possibilities for monitoring disturbances in myocardial perfusion...
  11. doi request reprint Level of agreement between laboratory and point-of-care prothrombin time before and after cardiopulmonary bypass in cardiac surgery
    Michael I Meesters
    Department of Anesthesiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands
    Thromb Res 133:1141-4. 2014
    ..This study investigated the level of agreement between the point-of-care prothrombin time (PT) with central laboratory PT before and after cardiopulmonary bypass...
  12. doi request reprint Health risk factors in the anesthesia population
    Willie H Scharwächter
    Department of Anaesthesiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands
    J Clin Anesth 32:33-9. 2016
    ....
  13. pmc Non-invasive measurements of pulse pressure variation and stroke volume variation in anesthetized patients using the Nexfin blood pressure monitor
    Jurre Stens
    Department of Anesthesiology, Institute for Cardiovascular Research, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands
    J Clin Monit Comput 30:587-94. 2016
    ..The SVV tended to be superior over PPV or Eadyn in predicting fluid responsiveness in our population. ..
  14. doi request reprint Microcirculatory perfusion during different perioperative hemodynamic strategies
    Jurre Stens
    Departments of Anaesthesiology of the VU University Medical Centre, Institute for Cardiovascular Research, Amsterdam, The Netherlands
    Microcirculation 22:267-75. 2015
    ..We investigated whether hemodynamic optimization of systemic tissue perfusion based on PPV and CI improves microcirculatory perfusion when compared to a MAP-based strategy in patients undergoing elective abdominal surgery...
  15. pmc Myocardial blood flow under general anaesthesia with sevoflurane in type 2 diabetic patients: a pilot study
    Carolien S E Bulte
    Department of Anaesthesiology, Institute for Cardiovascular Research, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
    Cardiovasc Diabetol 13:62. 2014
    ..The influence of sevoflurane anaesthesia on myocardial endothelial dysfunction in type 2 diabetic mellitus is investigated in this pilot study...
  16. ncbi request reprint Residual blood processing by centrifugation, cell salvage or ultrafiltration in cardiac surgery: effects on clinical hemostatic and ex-vivo rheological parameters
    Alexander B Vonk
    Department of Cardio Thoracic Surgery, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands
    Blood Coagul Fibrinolysis 23:622-8. 2012
    ..34 ± 1.92 vs. -0.77 ± 1.56 mmol/l; P = 0.03). Cell salvage is superior with respect to postoperative hemoglobin gain and washout of free hemoglobin when compared to centrifugation or ultrafiltration...
  17. doi request reprint Pulsatile flow during cardiopulmonary bypass preserves postoperative microcirculatory perfusion irrespective of systemic hemodynamics
    Nick J Koning
    Department of Anesthesiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands
    J Appl Physiol (1985) 112:1727-34. 2012
    ....
  18. ncbi request reprint Sphingosine kinase modulates microvascular tone and myogenic responses through activation of RhoA/Rho kinase
    Steffen Sebastian Bolz
    Institute of Physiology, Ludwig Maximilians University, Schillerstrasse 44, 80336 Muenchen, Germany
    Circulation 108:342-7. 2003
    ..RhoA and Rho kinase are important modulators of microvascular tone...
  19. doi request reprint H9c2 cardiomyoblasts produce thyroid hormone
    Christof Meischl
    VU University Medical Center, Department of Pathology, Amsterdam, The Netherlands
    Am J Physiol Cell Physiol 294:C1227-33. 2008
    ..In conclusion, our findings demonstrate for the first time that cardiomyocytes produce thyroid hormone in a manner adapted to the cell's environment...
  20. ncbi request reprint Cardioprotection via activation of protein kinase C-delta depends on modulation of the reverse mode of the Na+/Ca2+ exchanger
    R Arthur Bouwman
    Department of Anesthesiology, VU University Medical Center, De Boelelaan 1118, PO Box 7057, 1007 MB Amsterdam, Netherlands
    Circulation 114:I226-32. 2006
    ....
  21. ncbi request reprint Reactive oxygen species precede protein kinase C-delta activation independent of adenosine triphosphate-sensitive mitochondrial channel opening in sevoflurane-induced cardioprotection
    R Arthur Bouwman
    Department of Anesthesiology and the Laboratory for Physiology, Vrije Universiteit Medical Center Institute for Cardiovascular Research Vrije Universiteit, Amsterdam, The Netherlands
    Anesthesiology 100:506-14. 2004
    ....