Matthijs Vink

Summary

Affiliation: University Medical Center Utrecht
Country: The Netherlands

Publications

  1. ncbi Perceptual bias following visual target selection
    Matthijs Vink
    Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Heidelberglaan 100, 3584CX Utrecht, The Netherlands
    Neuroimage 25:1168-74. 2005
  2. ncbi Function of striatum beyond inhibition and execution of motor responses
    Matthijs Vink
    Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Department of Psychiatry, Heidelberglaan Utrecht, The Netherlands
    Hum Brain Mapp 25:336-44. 2005
  3. ncbi Striatal dysfunction in schizophrenia and unaffected relatives
    Matthijs Vink
    Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Heidelberglaan, Utrecht, The Netherlands
    Biol Psychiatry 60:32-9. 2006
  4. doi Prefrontal lobe dysfunction predicts treatment response in medication-naive first-episode schizophrenia
    Nicoletta M J van Veelen
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Schizophr Res 129:156-62. 2011
  5. doi Working memory and default mode network abnormalities in unaffected siblings of schizophrenia patients
    Max de Leeuw
    Brain Center Rudolf Magnus, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands Electronic address
    Schizophr Res 150:555-62. 2013
  6. doi Reduced proactive inhibition in schizophrenia is related to corticostriatal dysfunction and poor working memory
    Bram B Zandbelt
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, The Netherlands
    Biol Psychiatry 70:1151-8. 2011
  7. pmc A functional and structural investigation of the human fronto-basal volitional saccade network
    Sebastiaan F W Neggers
    Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, UMC Utrecht, The Netherlands
    PLoS ONE 7:e29517. 2012
  8. ncbi Brain activation during antisaccades in unaffected relatives of schizophrenic patients
    Mathijs Raemaekers
    Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    Biol Psychiatry 59:530-5. 2006
  9. doi Reduced language lateralization in first-episode medication-naive schizophrenia
    Nicoletta M J van Veelen
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Schizophr Res 127:195-201. 2011
  10. doi Reduced functional coupling in the default-mode network during self-referential processing
    Mariët van Buuren
    Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
    Hum Brain Mapp 31:1117-27. 2010

Collaborators

Detail Information

Publications40

  1. ncbi Perceptual bias following visual target selection
    Matthijs Vink
    Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Heidelberglaan 100, 3584CX Utrecht, The Netherlands
    Neuroimage 25:1168-74. 2005
    ..When this prior information conflicts with the current stimulus demands, compensatory motor actions are taken to correct this perceptual bias...
  2. ncbi Function of striatum beyond inhibition and execution of motor responses
    Matthijs Vink
    Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Department of Psychiatry, Heidelberglaan Utrecht, The Netherlands
    Hum Brain Mapp 25:336-44. 2005
    ..Our findings suggest that the striatum is critically involved in inhibitory motor control, most likely by controlling the execution of planned motor responses...
  3. ncbi Striatal dysfunction in schizophrenia and unaffected relatives
    Matthijs Vink
    Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Heidelberglaan, Utrecht, The Netherlands
    Biol Psychiatry 60:32-9. 2006
    ..First-degree relatives of patients were also tested to examine whether striatal abnormality is associated with schizophrenia, or with the risk for the illness...
  4. doi Prefrontal lobe dysfunction predicts treatment response in medication-naive first-episode schizophrenia
    Nicoletta M J van Veelen
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Schizophr Res 129:156-62. 2011
    ..These results suggest that prefrontal lobe dysfunction reflects a distinct neuropathological substrate in a subgroup of treatment non-responsive schizophrenia patients...
  5. doi Working memory and default mode network abnormalities in unaffected siblings of schizophrenia patients
    Max de Leeuw
    Brain Center Rudolf Magnus, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands Electronic address
    Schizophr Res 150:555-62. 2013
    ..Unaffected siblings of patients also show WM impairments. However, the nature of the functional deficits underlying these impairments is unclear, mainly because of impaired performance confounding neuroimaging results...
  6. doi Reduced proactive inhibition in schizophrenia is related to corticostriatal dysfunction and poor working memory
    Bram B Zandbelt
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, The Netherlands
    Biol Psychiatry 70:1151-8. 2011
    ....
  7. pmc A functional and structural investigation of the human fronto-basal volitional saccade network
    Sebastiaan F W Neggers
    Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, UMC Utrecht, The Netherlands
    PLoS ONE 7:e29517. 2012
    ..Alternatively, there could be a bias in published reports of monkey studies favoring the caudate nucleus over the putamen in the search for oculomotor functions...
  8. ncbi Brain activation during antisaccades in unaffected relatives of schizophrenic patients
    Mathijs Raemaekers
    Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    Biol Psychiatry 59:530-5. 2006
    ..In patients, the saccadic inhibition deficit has been related to impaired frontostriatal functioning. This study attempts to establish whether this abnormality is also present in unaffected relatives of patients...
  9. doi Reduced language lateralization in first-episode medication-naive schizophrenia
    Nicoletta M J van Veelen
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Schizophr Res 127:195-201. 2011
    ..001). LI was not correlated with the positive subscale of the PANSS, nor with hallucinations or disorganization. This is the first study to report reduced LI at the onset of schizophrenia, before medical treatment is initiated...
  10. doi Reduced functional coupling in the default-mode network during self-referential processing
    Mariët van Buuren
    Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
    Hum Brain Mapp 31:1117-27. 2010
    ..As such, these results provide an indication for functional specialization within the DMN and support the notion that each area of the DMN is involved in different subfunctions of self-referential processing...
  11. doi Default-mode network dysfunction and self-referential processing in healthy siblings of schizophrenia patients
    Mariët van Buuren
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Room A 01 126, P O Box 85500, 3508 GA Utrecht, The Netherlands
    Schizophr Res 142:237-43. 2012
    ....
  12. doi Exaggerated brain activation during emotion processing in unaffected siblings of patients with schizophrenia
    Mariët van Buuren
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Biol Psychiatry 70:81-7. 2011
    ..In this study, we investigated whether siblings of patients with schizophrenia show abnormal brain activation during basic emotion processing...
  13. pmc On the role of the striatum in response inhibition
    Bram B Zandbelt
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    PLoS ONE 5:e13848. 2010
    ..Here, we test three hypotheses regarding the role of the striatum in stopping: striatum activation during successful stopping may reflect suppression of M1, anticipation of a stop-signal occurring, or a slower response build-up...
  14. doi Within-subject variation in BOLD-fMRI signal changes across repeated measurements: quantification and implications for sample size
    Bram B Zandbelt
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Neuroimage 42:196-206. 2008
    ..In order to guide future studies, sample sizes are provided for a range of experimental effects and levels of stability. Obtaining estimates of these latter two variables is essential for selecting an appropriate number of subjects...
  15. doi Cardiorespiratory effects on default-mode network activity as measured with fMRI
    Mariët van Buuren
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Hum Brain Mapp 30:3031-42. 2009
    ..We take these results to indicate that the BOLD signal within the DMN cannot be explained by CR effects alone and is possibly related to some form of cognitive neuronal processing...
  16. doi Left dorsolateral prefrontal cortex dysfunction in medication-naive schizophrenia
    Nicoletta M J van Veelen
    Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Schizophr Res 123:22-9. 2010
    ..These results suggest that DLPFC function is deficient in the early phases of schizophrenia and cannot be attributed to the use of antipsychotics...
  17. doi The effect of aging on fronto-striatal reactive and proactive inhibitory control
    Iris Kleerekooper
    Brain Center Rudolf Magnus, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Neuroimage 132:51-8. 2016
    ....
  18. doi Expectations and violations: delineating the neural network of proactive inhibitory control
    Bram B Zandbelt
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Hum Brain Mapp 34:2015-24. 2013
    ..Rather than being involved in proactive inhibition, this network appears to be involved in processes associated with violation of expectations...
  19. doi Deep brain stimulation restores frontostriatal network activity in obsessive-compulsive disorder
    Martijn Figee
    Department of Psychiatry, Academic Medical Center, Amsterdam, The Netherlands
    Nat Neurosci 16:386-7. 2013
    ..Our findings suggest that DBS is able to reduce maladaptive activity and connectivity of the stimulated region...
  20. pmc DRD2 Schizophrenia-Risk Allele Is Associated With Impaired Striatal Functioning in Unaffected Siblings of Schizophrenia Patients
    Matthijs Vink
    Department of Psychiatry, University Medical Center Utrecht, Brain Center Rudolf Magnus, Utrecht, The Netherlands
    Schizophr Bull 42:843-50. 2016
    ..We take our findings to indicate that striatal functioning is impaired in carriers of the DRD2 risk allele, likely due to dopamine dysregulation at the DRD2 location. ..
  21. pmc Neural correlates of inhibition and contextual cue processing related to treatment response in PTSD
    Sanne J H van Rooij
    1 Brain Center Rudolf Magnus, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands 2 Research Centre Military Mental Healthcare, Ministry of Defence, Utrecht, The Netherlands
    Neuropsychopharmacology 40:667-75. 2015
    ..The IPL has an important role in contextual cue processing, and may therefore facilitate the effect of psychotherapy. Hence, increased left IPL activation may represent a potential predictive biomarker for PTSD treatment response. ..
  22. doi Frontostriatal activity and connectivity increase during proactive inhibition across adolescence and early adulthood
    Matthijs Vink
    Brain Center Rudolf Magnus, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Hum Brain Mapp 35:4415-27. 2014
    ..These data serve as a stepping stone to investigate abnormal development of the frontostriatal network in disorders such as schizophrenia and attention-deficit hyperactivity disorder...
  23. doi Dysfunctional reward circuitry in obsessive-compulsive disorder
    Martijn Figee
    Department of Psychiatry, Academic Medical Center, Amsterdam, The Netherlands
    Biol Psychiatry 69:867-74. 2011
    ..This is the first functional imaging study to investigate explicitly reward circuitry in OCD...
  24. doi Contribution of the left and right inferior frontal gyrus in recovery from aphasia. A functional MRI study in stroke patients with preserved hemodynamic responsiveness
    Casper A M M van Oers
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, The Netherlands
    Neuroimage 49:885-93. 2010
    ..Altered hemodynamic responsiveness seems an unlikely confounder in the interpretations of fMRI results...
  25. doi Trait and state dependent functional impairments in bipolar disorder
    Astrid Van der Schot
    Department of Psychiatry, University Medical Center Utrecht, The Netherlands
    Psychiatry Res 184:135-42. 2010
    ..These results add to the evidence for functional deficits in the affective network in BD patients, of which reduced bilateral OFC activation was found to be the most pronounced deficit across all mood states...
  26. ncbi Brain activation related to retrosaccades in saccade experiments
    Mathijs Raemaekers
    Rudolf Magnus Institute of Neuroscience, University Medical Center, Utrecht, The Netherlands
    Neuroreport 16:1043-7. 2005
    ..In the striatum, these negative responses were equal in size to the positive responses of the testsaccades. This could mask brain activity of testsaccades when not taken into account...
  27. pmc Predicting Treatment Outcome in PTSD: A Longitudinal Functional MRI Study on Trauma-Unrelated Emotional Processing
    Sanne J H van Rooij
    Brain Center Rudolf Magnus, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Neuropsychopharmacology 41:1156-65. 2016
    ..Such approaches are critical for defining parameters to customize PTSD treatment and improve treatment response rates. ..
  28. doi Diminishing striatal activation across adolescent development during reward anticipation in offspring of schizophrenia patients
    Matthijs Vink
    Brain Center Rudolf Magnus, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands Electronic address
    Schizophr Res 170:73-9. 2016
    ..These results, taken together with data from adult schizophrenia patients and their siblings, indicate that the diminishing striatal activation across adolescence may signify a familial vulnerability for schizophrenia. ..
  29. doi Different developmental trajectories for anticipation and receipt of reward during adolescence
    Janna Marie Hoogendam
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands Electronic address
    Dev Cogn Neurosci 6:113-24. 2013
    ..This study provides evidence for functional changes in the reward system which may underlie typical adolescent behaviour. ..
  30. doi Chronic effects of cannabis use on the human reward system: an fMRI study
    Hendrika H Van Hell
    Rudolf Magnus Institute of Neuroscience, Department of Neurology and Neurosurgery, Section Brain Function and Plasticity, University Medical Center, Utrecht, The Netherlands
    Eur Neuropsychopharmacol 20:153-63. 2010
    ..Our findings imply that chronic cannabis use as well as nicotine, may cause an altered brain response to rewarding stimuli...
  31. doi Changes in White Matter Organization in Adolescent Offspring of Schizophrenia Patients
    Max de Leeuw
    Brain Center Rudolf Magnus, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Neuropsychopharmacology 42:495-501. 2017
    ..These results indicate altered development of white matter in subjects who are at familial risk for schizophrenia and may precede frontostriatal white matter alterations in adult schizophrenia patients and siblings...
  32. pmc Fronto-striatal dysfunction during reward processing in unaffected siblings of schizophrenia patients
    Max de Leeuw
    Brain Center Rudolf Magnus, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Schizophr Bull 41:94-103. 2015
    ..Since unaffected siblings share on average 50% of their genes with their ill relatives, these deficits may be related to the genetic vulnerability for schizophrenia. ..
  33. doi Impact of aging on frontostriatal reward processing
    Matthijs Vink
    Brain Center Rudolf Magnus, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    Hum Brain Mapp 36:2305-17. 2015
    ..These changes are consistent the well-ocumented age-related decline of striatal dopamine availability, and may provide a stepping stone for further research of age-related neurodegenerative diseases...
  34. doi The role of stop-signal probability and expectation in proactive inhibition
    Matthijs Vink
    Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Room A 01 126, P O Box 85500, NL 3508 GA, Utrecht, The Netherlands
    Eur J Neurosci 41:1086-94. 2015
    ..These data show that proactive inhibition depends on both the processing of objective contextual task information and the subjective expectation of stop-signals. ..
  35. doi Functional differences in emotion processing during adolescence and early adulthood
    Matthijs Vink
    Brain Center Rudolf Magnus, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands Electronic address
    Neuroimage 91:70-6. 2014
    ..Understanding these developmental changes is important as these may underlie typical adolescent behavior. ..
  36. pmc A landscape-based cluster analysis using recursive search instead of a threshold parameter
    Thomas E Gladwin
    Military Mental Health Research Centre, Ministry of Defense, P O Box 90 000, 3509AA Utrecht, The Netherlands Brain Center Rudolf Magnus, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
    MethodsX 3:477-82. 2016
    ..The recursive method used for defining clusters, the method used for combining clusters, and the definition of the "value" of a cluster may be of interest for future variations. ..
  37. pmc Impaired right inferior frontal gyrus response to contextual cues in male veterans with PTSD during response inhibition
    Sanne J H van Rooij
    Brain Center Rudolf Magnus, Department of Psychiatry, University Medical Center Utrecht and the Research Centre, Military Mental Healthcare, Ministry of Defence, The Netherlands
    J Psychiatry Neurosci 39:330-8. 2014
    ..In this fMRI study, the role of contextual cues in response inhibition was investigated...
  38. pmc Human fronto-tectal and fronto-striatal-tectal pathways activate differently during anti-saccades
    Antoin D de Weijer
    Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht Utrecht, Netherlands
    Front Hum Neurosci 4:41. 2010
    ....
  39. doi Evidence of altered cortical and amygdala activation during social decision-making in schizophrenia
    Daan Baas
    Helmholtz Instituut, Department of Experimental Psychology, Universiteit Utrecht, PO Box 80125, 3508 TC, Utrecht, The Netherlands
    Neuroimage 40:719-27. 2008
    ..These findings suggest that the impairments in social cognition that are often observed in schizophrenia are, at least in part, related to altered brain activity in these areas...
  40. doi Effects of an extra X chromosome on language lateralization: an fMRI study with Klinefelter men (47,XXY)
    Sophie van Rijn
    Utrecht University, Helmholtz Institute, Department of Experimental Psychology, Heidelberglaan 2, 3584 CS, Utrecht, The Netherlands
    Schizophr Res 101:17-25. 2008
    ....