- Heat shock protein 60 reactive T cells in juvenile idiopathic arthritis: what is new?Yvonne Vercoulen
Department of Pediatric Immunology, Wilhelmina Children s Hospital, UMCU, Lundlaan 6 3584 EA, Utrecht, The Netherlands
Arthritis Res Ther 11:231. 2009..Overall, we will discuss the immune modulatory capacity of HSPs, and the underlying mechanisms of HSP60-mediated immune regulation in JIA, and how this can be translated into therapy...
- Human regulatory T cell suppressive function is independent of apoptosis induction in activated effector T cellsYvonne Vercoulen
Department of Pediatric Immunology, Center for Molecular and Cellular Intervention, Wilhelmina Children s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
PLoS ONE 4:e7183. 2009..Experiments in mice demonstrated that Treg restrict effector T cell (Teff) responses by deprivation of the growth factor IL-2 through Treg consumption, resulting in apoptosis of Teff...