Frans H Rutten

Summary

Affiliation: University Medical Center Utrecht
Country: The Netherlands

Publications

  1. ncbi request reprint [Heart failure with preserved ejection fraction: Diastolic heart failure]
    Frans H Rutten
    divisie Julius Centrum voor Gezondheidswetenschappen en Eerstelijnsgeneeskunde, afd Huisartsgeneeskunde, Universitair Medisch Centrum Utrecht, The Netherlands
    Ned Tijdschr Geneeskd 156:A5315. 2012
  2. ncbi request reprint [Adherence to lifestyle recommendations of patients with heart failure: one size fits all?]
    Frans H Rutten
    Universitair Medisch Centrum Utrecht, Julius Centrum voor Gezondheidswetenschappen en Eerstelijns Geneeskunde, Utrecht, The Netherlands
    Ned Tijdschr Geneeskd 157:A6034. 2013
  3. doi request reprint Primary care patients with heart failure in the last year of their life
    Frans H Rutten
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht
    Fam Pract 29:36-42. 2012
  4. pmc Early recognition of heart failure in patients with diabetes type 2 in primary care. A prospective diagnostic efficiency study. (UHFO-DM2)
    Leandra J M Boonman-de Winter
    Center for Diagnostic Support in Primary Care SHL, Department of Scientific and Contract Research WECOR, Bredaseweg 165, 4872 LA Etten Leur, The Netherlands
    BMC Public Health 9:479. 2009
  5. doi request reprint Cardiovascular magnetic resonance imaging to identify left-sided chronic heart failure in stable patients with chronic obstructive pulmonary disease
    Frans H Rutten
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands
    Am Heart J 156:506-12. 2008
  6. doi request reprint β-blockers and their mortality benefits: underprescribed in heart failure and chronic obstructive pulmonary disease
    Frans H Rutten
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Future Cardiol 7:43-53. 2011
  7. ncbi request reprint [Remarkable results with candesartan]
    Frans H Rutten
    Universitair Medisch Centrum Utrecht, Julius Centrum voor Gezondheidswetenschappen en Eerstelijns Geneeskunde, Utrecht, The Netherlands
    Ned Tijdschr Geneeskd 155:A3313. 2011
  8. doi request reprint Beta-blockers may reduce mortality and risk of exacerbations in patients with chronic obstructive pulmonary disease
    Frans H Rutten
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85060, Stratenum 6 101, 3508 AB Utrecht, The Netherlands
    Arch Intern Med 170:880-7. 2010
  9. doi request reprint Highlights of the 2011 scientific sessions of the Congress of the Heart Failure Association of the European Society of Cardiology
    Frans H Rutten
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, 3508AB Utrecht, The Netherlands
    Future Cardiol 7:739-43. 2011
  10. ncbi request reprint B-type natriuretic peptide assays for detecting heart failure in the elderly: same value as those in the younger?
    Frans H Rutten
    Utrecht Heart Failure Organisation UHFO, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85060, Stratenum 6 131, 3508 AB Utrecht, The Netherlands
    Int J Cardiol 125:161-5. 2008

Collaborators

Detail Information

Publications61

  1. ncbi request reprint [Heart failure with preserved ejection fraction: Diastolic heart failure]
    Frans H Rutten
    divisie Julius Centrum voor Gezondheidswetenschappen en Eerstelijnsgeneeskunde, afd Huisartsgeneeskunde, Universitair Medisch Centrum Utrecht, The Netherlands
    Ned Tijdschr Geneeskd 156:A5315. 2012
    ..Evidence-based drug therapy for HF-PEF is currently lacking; ongoing studies are evaluating medications other than the well-established drugs used to treat HF-REF...
  2. ncbi request reprint [Adherence to lifestyle recommendations of patients with heart failure: one size fits all?]
    Frans H Rutten
    Universitair Medisch Centrum Utrecht, Julius Centrum voor Gezondheidswetenschappen en Eerstelijns Geneeskunde, Utrecht, The Netherlands
    Ned Tijdschr Geneeskd 157:A6034. 2013
    ..Clever use of telemonitoring could be useful in patient-tailored coaching when comorbidities, drug interactions, and the frequent exacerbations of heart failure are taken into account...
  3. doi request reprint Primary care patients with heart failure in the last year of their life
    Frans H Rutten
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht
    Fam Pract 29:36-42. 2012
    ..Quantitative information about the management of patients with advanced heart failure (HF) is scarce...
  4. pmc Early recognition of heart failure in patients with diabetes type 2 in primary care. A prospective diagnostic efficiency study. (UHFO-DM2)
    Leandra J M Boonman-de Winter
    Center for Diagnostic Support in Primary Care SHL, Department of Scientific and Contract Research WECOR, Bredaseweg 165, 4872 LA Etten Leur, The Netherlands
    BMC Public Health 9:479. 2009
    ....
  5. doi request reprint Cardiovascular magnetic resonance imaging to identify left-sided chronic heart failure in stable patients with chronic obstructive pulmonary disease
    Frans H Rutten
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands
    Am Heart J 156:506-12. 2008
    ..Although cardiovascular magnetic resonance imaging (CMR) is well established, its diagnostic accuracy in identifying chronic heart failure (CHF) in patients with chronic obstructive pulmonary disease (COPD) has not yet been quantified...
  6. doi request reprint β-blockers and their mortality benefits: underprescribed in heart failure and chronic obstructive pulmonary disease
    Frans H Rutten
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Future Cardiol 7:43-53. 2011
    ....
  7. ncbi request reprint [Remarkable results with candesartan]
    Frans H Rutten
    Universitair Medisch Centrum Utrecht, Julius Centrum voor Gezondheidswetenschappen en Eerstelijns Geneeskunde, Utrecht, The Netherlands
    Ned Tijdschr Geneeskd 155:A3313. 2011
    ..Finally, there was considerable (selective) loss-to-follow-up, which could also have led to bias. Head-to-head comparisons of drugs should be done with equipotential dosages in an RCT, not in an observational study...
  8. doi request reprint Beta-blockers may reduce mortality and risk of exacerbations in patients with chronic obstructive pulmonary disease
    Frans H Rutten
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85060, Stratenum 6 101, 3508 AB Utrecht, The Netherlands
    Arch Intern Med 170:880-7. 2010
    ..We assessed the long-term effect of beta-blocker use on survival and exacerbations in patients with COPD...
  9. doi request reprint Highlights of the 2011 scientific sessions of the Congress of the Heart Failure Association of the European Society of Cardiology
    Frans H Rutten
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, 3508AB Utrecht, The Netherlands
    Future Cardiol 7:739-43. 2011
    ..Over 700 abstracts, along with many invited programs and several satellite programs were presented. Some of the late-breaking clinical trials are summarized here...
  10. ncbi request reprint B-type natriuretic peptide assays for detecting heart failure in the elderly: same value as those in the younger?
    Frans H Rutten
    Utrecht Heart Failure Organisation UHFO, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85060, Stratenum 6 131, 3508 AB Utrecht, The Netherlands
    Int J Cardiol 125:161-5. 2008
    ....
  11. ncbi request reprint Comparison of B-type natriuretic peptide assays for identifying heart failure in stable elderly patients with a clinical diagnosis of chronic obstructive pulmonary disease
    Frans H Rutten
    Utrecht Heart Failure Organisation, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
    Eur J Heart Fail 9:651-9. 2007
    ..To compare the ability of different B-type natriuretic peptide (BNP) assays to identify heart failure in stable elderly patients with a diagnosis of chronic obstructive pulmonary disease (COPD)...
  12. pmc Improving the quality and clinical relevance of diagnostic studies
    Frans H Rutten
    Julius Centre for Health Sciences and Primary Care, University Medical Centre, Utrecht, 3508 AB, Netherlands
    BMJ 332:1129. 2006
  13. ncbi request reprint Heart failure and chronic obstructive pulmonary disease: An ignored combination?
    Frans H Rutten
    Utrecht Heart Failure Organisation UHFO, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85060, Stratenum 6 101, 3508 AB Utrecht, The Netherlands
    Eur J Heart Fail 8:706-11. 2006
    ..Further, to discuss diagnostic and therapeutic implications of the co-existence of both syndromes...
  14. pmc Recognising heart failure in elderly patients with stable chronic obstructive pulmonary disease in primary care: cross sectional diagnostic study
    Frans H Rutten
    Julius Centre for Health Sciences and Primary Care, University Medical Centre, Utrecht, 3508AB Netherlands
    BMJ 331:1379. 2005
    ....
  15. pmc Development and validation of a model to predict the risk of exacerbations in chronic obstructive pulmonary disease
    Loes C M Bertens
    Julius Center for Health Sciences and Primary Care, Utrecht, The Netherlands
    Int J Chron Obstruct Pulmon Dis 8:493-9. 2013
    ..Prediction models for exacerbations in patients with chronic obstructive pulmonary disease (COPD) are scarce. Our aim was to develop and validate a new model to predict exacerbations in patients with COPD...
  16. pmc Cost-effectiveness of screening strategies to detect heart failure in patients with type 2 diabetes
    Anoukh van Giessen
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Cardiovasc Diabetol 15:48. 2016
    ..Because both types of HF may be uncovered in older T2DM, screening may improve health outcomes at acceptable costs. We assessed the cost-effectiveness of five screening strategies in patients with T2DM aged 60 years or over...
  17. doi request reprint Gender differences in pre-hospital time delay and symptom presentation in patients suspected of acute coronary syndrome in primary care
    Madeleine H E Bruins Slot
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Fam Pract 29:332-7. 2012
    ..To describe gender differences in pre-hospital delay times and symptom presentation in patients suspected of acute coronary syndrome (ACS) in a primary care setting...
  18. doi request reprint Electrocardiographic characteristics of patients with chronic obstructive pulmonary disease
    Miriam J Warnier
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    COPD 10:62-71. 2013
    ..This underlines the importance of an integrated-care approach for COPD patients, paying attention to early detection of unrecognized coexisting cardiac disorders...
  19. ncbi request reprint Diagnosis and management of heart failure: a questionnaire among general practitioners and cardiologists
    Frans H Rutten
    Utrecht Heart Failure Organisation UHFO, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, P O Box 85500, Stratenum 6 101, 3508 AB Utrecht, The Netherlands
    Eur J Heart Fail 5:345-8. 2003
  20. ncbi request reprint Differences between general practitioners and cardiologists in diagnosis and management of heart failure: a survey in every-day practice
    Frans H Rutten
    Utrecht Heart Failure Organisation UHFO, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, P O Box 85500, Stratenum 6 101, 3508 AB Utrecht, The Netherlands
    Eur J Heart Fail 5:337-44. 2003
    ..Data on diagnosis and management of heart failure in every-day care are scarce...
  21. doi request reprint Cardiac arrhythmias in adult patients with asthma
    Miriam J Warnier
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
    J Asthma 49:942-6. 2012
    ..The aim of this study was to determine whether asthma is associated with the risk of cardiac arrhythmias and electrocardiographic characteristics of arrhythmogenicity (ECG) and to explore the role of β2-mimetics...
  22. ncbi request reprint Unrecognized heart failure in elderly patients with stable chronic obstructive pulmonary disease
    Frans H Rutten
    Utrecht Heart Failure Organisation UHFO, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85060, Stratenum 6 101, 3508 AB Utrecht, The Netherlands
    Eur Heart J 26:1887-94. 2005
    ..To establish the prevalence of unrecognized heart failure in elderly patients with a diagnosis of chronic obstructive pulmonary disease, in a stable phase of their disease...
  23. doi request reprint Balance measures for propensity score methods: a clinical example on beta-agonist use and the risk of myocardial infarction
    Rolf H H Groenwold
    Department of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Utrecht, The Netherlands
    Pharmacoepidemiol Drug Saf 20:1130-7. 2011
    ..Our objective was to compare balance measures in clinical data and assessed the association between long-acting inhalation beta-agonist (LABA) use and myocardial infarction...
  24. pmc Extended prediction rule to optimise early detection of heart failure in older persons with non-acute shortness of breath: a cross-sectional study
    Evelien E S van Riet
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    BMJ Open 6:e008225. 2016
    ..The original rule included a history of ischaemic heart disease, body mass index, laterally displaced apex beat, heart rate, elevated N-terminal pro B-type natriuretic peptide and an abnormal ECG...
  25. pmc Diagnostic and prognostic utility of mid-expiratory flow rate in older community-dwelling persons with respiratory symptoms, but without chronic obstructive pulmonary disease
    Gülmisal Güder
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    BMC Pulm Med 15:83. 2015
    ..A reduced MEF50 has been suggested as a surrogate marker of small airways disease. The diagnostic and prognostic utility of this easy to assess spirometric variable in persons with respiratory symptoms, but without COPD is unclear...
  26. pmc Use of expert panels to define the reference standard in diagnostic research: a systematic review of published methods and reporting
    Loes C M Bertens
    Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, The Netherlands
    PLoS Med 10:e1001531. 2013
    ..The aim of this study is to provide an overview of methods used in panel diagnoses and to provide initial guidance on the use and reporting of panel diagnosis as reference standard...
  27. doi request reprint The impact of heart failure on the classification of COPD severity
    Gülmisal Güder
    Comprehensive Heart Failure Center, University of Wurzburg, Wurzburg, Germany
    J Card Fail 18:637-44. 2012
    ..We compared pulmonary function in patients with either HF or COPD, or the combination to assess whether grading of COPD using the Global Initiative of Chronic Obstructive Lung Disease classification is hampered in the presence of HF...
  28. doi request reprint Epidemiology of heart failure: the prevalence of heart failure and ventricular dysfunction in older adults over time. A systematic review
    Evelien E S van Riet
    Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, PO Box 85500, 3508 AB Utrecht, The Netherlands
    Eur J Heart Fail 18:242-52. 2016
    ..The prevalence of diastolic dysfunction is on the rise and currently higher than that of systolic dysfunction. The prevalence of the latter seems to have decreased in the 21st century. ..
  29. doi request reprint Unrecognized heart failure and chronic obstructive pulmonary disease (COPD) in frail elderly detected through a near-home targeted screening strategy
    Yvonne van Mourik
    From the Julius Center for Health Sciences and Primary care YvM, JBR, KGMM, AWH, FHR, The Department of Cardiology, Heart Lung Center MJMC, and the Department of Respiratory Medicine J WJL, University Medical Center Utrecht, Utrecht, The Netherlands
    J Am Board Fam Med 27:811-21. 2014
    ..We want to determine the prevalence of previously unrecognized HF, COPD, and other chronic diseases in frail older people using a near-home targeted screening strategy...
  30. doi request reprint Safety information on QT-interval prolongation: comparison of European Union and United States drug labeling
    Miriam J Warnier
    Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, The Netherlands Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Drug Discov Today 19:1294-7. 2014
    ..434). However, the agreement in expected clinical decisions based on the product labels was much higher (kappa 0.673). The US drug label tends to be more explicit, especially when it considers absence of QT effects. ..
  31. doi request reprint COPD detected with screening: impact on patient management and prognosis
    Loes C M Bertens
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Eur Respir J 44:1571-8. 2014
    ..Our study underlines the importance of obtaining follow-up data to assess the true impact of a (screen-detected) diagnosis of COPD on patient management and outcome. ..
  32. doi request reprint Point-of-care tests in suspected acute myocardial infarction: a systematic review
    Madeleine H E Bruins Slot
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85500, 3508 GA Utrecht, The Netherlands
    Int J Cardiol 168:5355-62. 2013
    ..A review of cardiac point-of-care (POC) tests used to detect or exclude acute myocardial infarction (AMI) with a focus on test performance within 6 hours after the start of symptoms...
  33. doi request reprint The furosemide diagnostic test in suspected slow-onset heart failure: popular but not useful
    Johannes C Kelder
    Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands
    Eur J Heart Fail 13:513-7. 2011
    ..We asked general practitioners (GPs) about their actual use of the furosemide test and studied the diagnostic accuracy in patients with suspected heart failure...
  34. doi request reprint Heart-type fatty acid-binding protein in the early diagnosis of acute myocardial infarction: a systematic review and meta-analysis
    Madeleine H E Bruins Slot
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, GA Utrecht, The Netherlands
    Heart 96:1957-63. 2010
    ..The introduction of early and safe biomarkers could lead to (a) a large reduction in unnecessary hospital referrals of patients suspected of, but not, having AMI and (b) an earlier start of treatment in patients with AMI...
  35. doi request reprint A nomogram was developed to enhance the use of multinomial logistic regression modeling in diagnostic research
    Loes C M Bertens
    Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, PO Box 85060, Stratenum 6 131, Utrecht 3508 AB, The Netherlands Electronic address
    J Clin Epidemiol 71:51-7. 2016
    ..We developed a nomogram to facilitate the interpretation and presentation of results from multinomial logistic regression models...
  36. doi request reprint Prevalence of unrecognized heart failure in older persons with shortness of breath on exertion
    Evelien E S van Riet
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85500, 3508 AB, Utrecht, The Netherlands
    Eur J Heart Fail 16:772-7. 2014
    ..We assessed the prevalence of unrecognized heart failure in elderly patients presenting to primary care with shortness of breath on exertion...
  37. doi request reprint Prevalence and underlying causes of dyspnoea in older people: a systematic review
    Yvonne van Mourik
    Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, Netherlands
    Age Ageing 43:319-26. 2014
    ..Information on the exact prevalence and distribution of underlying causes is scarce. Our aim was to review the literature on prevalence and underlying causes of dyspnoea in the older population...
  38. pmc Triage of frail elderly with reduced exercise tolerance in primary care (TREE). A clustered randomized diagnostic study
    Yvonne van Mourik
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85500, Stratenum 6, 131, 3508, AB, Utrecht, The Netherlands
    BMC Public Health 12:385. 2012
    ....
  39. doi request reprint The potential yield of ECG screening of hypertensive patients: the Utrecht Health Project
    Tjarda Scheltens
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
    J Hypertens 28:1527-33. 2010
    ..We estimated the prevalence of clinically relevant ECG abnormalities and the number needed to screen (NNS) with a routine ECG to prevent the occurrence of one death in the next 10 years conditional on adequate treatment and follow-up...
  40. doi request reprint Effect of training general practitioners in drug treatment of newly detected heart failure patients with reduced or preserved ejection fraction: A cluster randomized trial
    Evelien E S van Riet
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, 3508 AB Utrecht, The Netherlands Electronic address
    Int J Cardiol 217:174-82. 2016
    ..To assess the effect of training general practitioners (GPs) in the optimization of drug treatment for newly detected heart failure (HF)...
  41. pmc Rationale, design and baseline results of the Treatment Optimisation in Primary care of Heart failure in the Utrecht region (TOPHU) study: a cluster randomised controlled trial
    Mark J Valk
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85500, 3508 AB, Utrecht, The Netherlands
    BMC Fam Pract 16:130. 2015
    ..In this study we assess the effect of a single training of GPs in the pharmacological management of patients with HF...
  42. pmc Strategy to recognize and initiate treatment of chronic heart failure in primary care (STRETCH): a cluster randomized trial
    Evelien E S van Riet
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85500, 3508 AB, Utrecht, The Netherlands
    BMC Cardiovasc Disord 14:1. 2014
    ..We assessed whether implementation of a diagnostic-therapeutic strategy improves functionality, health-related quality of life, and uptake of heart failure medication in primary care...
  43. pmc Resting heart rate is a risk factor for mortality in chronic obstructive pulmonary disease, but not for exacerbations or pneumonia
    Miriam J Warnier
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands
    PLoS ONE 9:e105152. 2014
    ..We assessed whether heart rate is associated with all-cause mortality, and non-fatal pulmonary endpoints...
  44. doi request reprint Quality of drug label information on QT interval prolongation
    Miriam J Warnier
    Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, The Netherlands Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Int J Risk Saf Med 26:89-98. 2014
    ..Information regarding QT-prolongation in the drug label may vary between products. This could lead to suboptimal risk minimization strategies...
  45. doi request reprint The impact of concurrent heart failure on prognosis in patients with chronic obstructive pulmonary disease
    Laura C M Boudestein
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Eur J Heart Fail 11:1182-8. 2009
    ..To compare prognosis in patients with chronic obstructive pulmonary disease (COPD) with or without concomitant heart failure...
  46. doi request reprint High cumulative incidence of cancer in patients with cardio-renal-anaemia syndrome
    Nicolas F Schroten
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Eur J Heart Fail 12:855-60. 2010
    ..Both have been associated with the development of cancer. This study aimed to determine the cumulative incidence of cancer in patients with CRA, as compared with anaemic CKD and control patients...
  47. ncbi request reprint [Summary of the practice guideline 'Atrial fibrillation' (first revision) from the Dutch College of General Practitioners]
    Wim Opstelten
    Nederlands Huisartsen Genootschap, afd Richtlijnontwikkeling en Wetenschap, Utrecht, The Netherlands
    Ned Tijdschr Geneeskd 154:A1570. 2010
    ..The adequacy of antithrombotic treatment should be reassessed yearly...
  48. doi request reprint Efficiently screening heart failure in patients with type 2 diabetes
    Leandra J M Boonman-de Winter
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands Center for Diagnostic Support in Primary Care SHL Groep, Department of Scientific Research, Etten Leur, The Netherlands
    Eur J Heart Fail 17:187-95. 2015
    ..Our aim was to develop a screening tool for heart failure in patients with type 2 diabetes...
  49. doi request reprint Chronic obstructive pulmonary disease in heart failure: accurate diagnosis and treatment
    Gülmisal Güder
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands Comprehensive Heart Failure Center, University of Wurzburg, Wurzburg, Germany Department of Internal Medicine Cardiology, University Hospital Wurzburg, Germany
    Eur J Heart Fail 16:1273-82. 2014
    ....
  50. doi request reprint Clinically relevant diagnostic research in primary care: the example of B-type natriuretic peptides in the detection of heart failure
    Johannes C Kelder
    Julius Center for Health Sciences and Primary Care, University Medical Centre Utrecht, The Netherlands
    Fam Pract 26:69-74. 2009
    ....
  51. pmc COPD in patients with stable heart failure in the primary care setting
    Mark J Valk
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Amersfoort, The Netherlands
    Int J Chron Obstruct Pulmon Dis 10:1219-24. 2015
    ..Exact prevalence estimates are lacking because most previous studies estimated the prevalence of COPD among HF patients while unstable and in the presence of pulmonary congestion...
  52. doi request reprint Effectiveness of an interactive platform, and the ESC/HFA heartfailurematters.org website in patients with heart failure: design of the multicentre randomized e-Vita heart failure trial
    Kim P Wagenaar
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
    Eur J Heart Fail 17:1310-6. 2015
    ..org (HFM website) improves self-care when added to usual care. Finally, we aim to evaluate the cost-effectiveness of these interventions...
  53. pmc Measurement of ECG abnormalities and cardiovascular risk classification: a cohort study of primary care patients in the Netherlands
    Anne Groot
    Department of Experimental Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Br J Gen Pract 65:e1-8. 2015
    ..GPs need accurate tools for cardiovascular (CV) risk assessment. Abnormalities in resting electrocardiograms (ECGs) relate to increased CV risk...
  54. doi request reprint Smoking cessation strategies in patients with COPD
    Miriam J Warnier
    Dept of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht, The Netherlands
    Eur Respir J 41:727-34. 2013
    ..Neither the intensity of counselling nor the type of anti-smoking drug made a difference...
  55. pmc Heart-type Fatty acid-binding protein in Acute Myocardial infarction Evaluation (FAME): background and design of a diagnostic study in primary care
    Madeleine H E Bruins Slot
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85500, 3508 GA Utrecht, The Netherlands
    BMC Cardiovasc Disord 8:8. 2008
    ....
  56. doi request reprint Determinants of patient's and doctor's delay in diagnosis and treatment of colorectal cancer
    Afke M G H Van Hout
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
    Eur J Gastroenterol Hepatol 23:1056-63. 2011
    ..Early detection and treatment is important for the management of colorectal cancer (CRC)...
  57. ncbi request reprint Is treatment of atrial fibrillation in primary care based on thromboembolic risk assessment?
    Frans H Rutten
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
    Fam Pract 20:16-21. 2003
    ..Although practice studies have shown underutilization of antithrombotics, it is not clear whether physicians make use of thromboembolic risk stratification in their treatment decisions, as recommended in current guidelines...
  58. pmc Yield of screening for atrial fibrillation in primary care with a hand-held, single-lead electrocardiogram device during influenza vaccination
    Femke Kaasenbrood
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Strat 6 131, PO Box 85500, Utrecht 3508 GA, The Netherlands
    Europace 18:1514-1520. 2016
    ..To assess the yield of screening for atrial fibrillation (AF) with a hand-held single-lead electrocardiogram (ECG) device during influenza vaccination in primary care in the Netherlands...
  59. pmc Serum biomarkers for the early diagnosis of TIA: The MIND-TIA study protocol
    L Servaas Dolmans
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    BMC Neurol 15:119. 2015
    ..Our aim is to quantify the added diagnostic value of serum biomarkers of brain ischaemia in patients suspected of TIA...
  60. pmc "GOLD or lower limit of normal definition? A comparison with expert-based diagnosis of chronic obstructive pulmonary disease in a prospective cohort-study"
    Gülmisal Güder
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Respir Res 13:13. 2012
    ..We wanted to assess the diagnostic accuracy and prognostic capability of the GOLD and LLN definition when compared to an expert-based diagnosis...