Berent Prakken

Summary

Affiliation: University Medical Center Utrecht
Country: The Netherlands

Publications

  1. pmc Cerebral ischemia initiates an immediate innate immune response in neonates during cardiac surgery
    Selma O Algra
    Department of Pediatric Cardiothoracic Surgery, Wilhelmina Children s Hospital, University Medical Center Utrecht, Lundlaan 6, Utrecht, EA 3584, The Netherlands
    J Neuroinflammation 10:24. 2013
  2. doi request reprint TLR9 agonist CpG enhances protective nasal HSP60 peptide vaccine efficacy in experimental autoimmune arthritis
    Evelien Zonneveld-Huijssoon
    Department of Pediatric Immunology, University Medical Centre Utrecht, Centre for Molecular and Cellular Intervention, Lundlaan 6, 3584 EA Utrecht, The Netherlands
    Ann Rheum Dis 71:1706-15. 2012
  3. pmc Prerequisites for cytokine measurements in clinical trials with multiplex immunoassays
    Wilco de Jager
    Department of Pediatric Immunology, Centre for Molecular and Cellular Intervention CMCI, University Medical Centre Utrecht, Utrecht, The Netherlands
    BMC Immunol 10:52. 2009
  4. pmc Expression of the inflammatory chemokines CCL5, CCL3 and CXCL10 in juvenile idiopathic arthritis, and demonstration of CCL5 production by an atypical subset of CD8+ T cells
    Daniel S Pharoah
    Rheumatology Unit, Institute of Child Health, UCL, London, UK
    Arthritis Res Ther 8:R50. 2006
  5. pmc Novel self-epitopes derived from aggrecan, fibrillin, and matrix metalloproteinase-3 drive distinct autoreactive T-cell responses in juvenile idiopathic arthritis and in health
    Sylvia Kamphuis
    Department of Paediatric Immunology and IACOPO, Institute for Translational Medicine, University Medical Center Utrecht, PO Box 85090, 3508 AB Utrecht, The Netherlands
    Arthritis Res Ther 8:R178. 2006
  6. doi request reprint Bystander suppression of experimental arthritis by nasal administration of a heat shock protein peptide
    Evelien Zonneveld-Huijssoon
    Department of Pediatric Immunology, Centre for Molecular and Cellular Intervention, University Medical Centre Utrecht, The Netherlands
    Ann Rheum Dis 70:2199-206. 2011
  7. doi request reprint Autologous bone marrow transplantation in autoimmune arthritis restores immune homeostasis through CD4+CD25+Foxp3+ regulatory T cells
    Sarah T A Roord
    Department of Pediatric Immunology, University Medical Center Utrecht, Wilhelmina Children s Hospital, Utrecht, USA
    Blood 111:5233-41. 2008
  8. ncbi request reprint Restoration of the immune balance by autologous bone marrow transplantation in juvenile idiopathic arthritis
    Eveline Delemarre
    Departement of Pediatric Immunology, Wilhelmina Children s Hospital, University Medical Center Utrecht, The Netherlands
    Curr Stem Cell Res Ther 6:3-9. 2011
  9. ncbi request reprint Autologous stem cell transplantation for autoimmunity induces immunologic self-tolerance by reprogramming autoreactive T cells and restoring the CD4+CD25+ immune regulatory network
    Isme de Kleer
    University Medical Center Utrecht, Wilhelmina Children s Hospital, Home Mailbox KC 03 063 0, Department of Pediatric Immunology, PO Box 85090, 3508 AB Utrecht, The Netherlands
    Blood 107:1696-702. 2006
  10. ncbi request reprint Refractory juvenile idiopathic arthritis: using autologous stem cell transplantation as a treatment strategy
    Nico M Wulffraat
    Department of Pediatric Immunology, University Medical Center Utrecht, Wilhelmina Children s Hospital, 3508 AB Utrecht, The Netherlands
    Expert Rev Mol Med 8:1-11. 2006

Collaborators

  • Wilco de Jager
  • Willem van Eden
  • Nico M Wulffraat
  • Evelien Zonneveld-Huijssoon
  • Femke van Wijk
  • Wietse Kuis
  • Eveline Delemarre
  • Mark Klein
  • Salvatore Albani
  • Sarah T A Roord
  • Selma O Algra
  • Jenny Meerding
  • Sarah Roord
  • Arash Ronaghy
  • Mark R Klein
  • Isme de Kleer
  • Daniel S Pharoah
  • Sylvia Kamphuis
  • Alvin W L Schadenberg
  • Fabiola C M Evens
  • Leo Koenderman
  • Felix Haas
  • Nicolaas J G Jansen
  • Kathelijne M Groeneveld
  • Marianne Boes
  • Eyal Raz
  • Stephen M Anderton
  • Ger T Rijkers
  • Anton Martens
  • Louis Boon
  • Bas Vastert
  • Salvo Albani
  • Marca H M Wauben
  • Nigel Klein
  • Richard W Tatham
  • Jolanda H M van Bilsen
  • Lucy R Wedderburn
  • Kolbrun Hrafnkelsdottir
  • Ger Arkesteijn
  • Gijs Teklenburg
  • Hemlata Varsani
  • Katy R Newton
  • Gisella Puga Yung
  • Margje H Haverkamp

Detail Information

Publications14

  1. pmc Cerebral ischemia initiates an immediate innate immune response in neonates during cardiac surgery
    Selma O Algra
    Department of Pediatric Cardiothoracic Surgery, Wilhelmina Children s Hospital, University Medical Center Utrecht, Lundlaan 6, Utrecht, EA 3584, The Netherlands
    J Neuroinflammation 10:24. 2013
    ..However, little is known about the immediate innate immune response in the first minutes after an ischemic insult in humans. We utilized the use of circulatory arrest during cardiac surgery to assess this...
  2. doi request reprint TLR9 agonist CpG enhances protective nasal HSP60 peptide vaccine efficacy in experimental autoimmune arthritis
    Evelien Zonneveld-Huijssoon
    Department of Pediatric Immunology, University Medical Centre Utrecht, Centre for Molecular and Cellular Intervention, Lundlaan 6, 3584 EA Utrecht, The Netherlands
    Ann Rheum Dis 71:1706-15. 2012
    ..The authors focused on the Toll-like receptor 9 ligand CpG, which was shown to stimulate regulatory T-cell proliferation when added to plasmacytoid dendritic cells (pDC) using in-vitro cultures...
  3. pmc Prerequisites for cytokine measurements in clinical trials with multiplex immunoassays
    Wilco de Jager
    Department of Pediatric Immunology, Centre for Molecular and Cellular Intervention CMCI, University Medical Centre Utrecht, Utrecht, The Netherlands
    BMC Immunol 10:52. 2009
    ..Therefore we set out to investigate several processes that might impact cytokine profiles such as blood collecting tubes, duration of storage, and number of freeze thawing cycles...
  4. pmc Expression of the inflammatory chemokines CCL5, CCL3 and CXCL10 in juvenile idiopathic arthritis, and demonstration of CCL5 production by an atypical subset of CD8+ T cells
    Daniel S Pharoah
    Rheumatology Unit, Institute of Child Health, UCL, London, UK
    Arthritis Res Ther 8:R50. 2006
    ..We believe this to be the first in depth analysis of these mediators of inflammation in JIA...
  5. pmc Novel self-epitopes derived from aggrecan, fibrillin, and matrix metalloproteinase-3 drive distinct autoreactive T-cell responses in juvenile idiopathic arthritis and in health
    Sylvia Kamphuis
    Department of Paediatric Immunology and IACOPO, Institute for Translational Medicine, University Medical Center Utrecht, PO Box 85090, 3508 AB Utrecht, The Netherlands
    Arthritis Res Ther 8:R178. 2006
    ..Additional experiments need to be performed to explore their qualities and role in disease pathogenesis in further detail...
  6. doi request reprint Bystander suppression of experimental arthritis by nasal administration of a heat shock protein peptide
    Evelien Zonneveld-Huijssoon
    Department of Pediatric Immunology, Centre for Molecular and Cellular Intervention, University Medical Centre Utrecht, The Netherlands
    Ann Rheum Dis 70:2199-206. 2011
    ..A study was undertaken to determine whether mucosal administration of these bystander epitopes can be similarly effective in suppressing arthritis...
  7. doi request reprint Autologous bone marrow transplantation in autoimmune arthritis restores immune homeostasis through CD4+CD25+Foxp3+ regulatory T cells
    Sarah T A Roord
    Department of Pediatric Immunology, University Medical Center Utrecht, Wilhelmina Children s Hospital, Utrecht, USA
    Blood 111:5233-41. 2008
    ..This work provided further insight into the role of Tregs in restoration of the immune balance by aBMT and can open the way to explore therapeutic interventions to further improve treatment of AID and disease relapses...
  8. ncbi request reprint Restoration of the immune balance by autologous bone marrow transplantation in juvenile idiopathic arthritis
    Eveline Delemarre
    Departement of Pediatric Immunology, Wilhelmina Children s Hospital, University Medical Center Utrecht, The Netherlands
    Curr Stem Cell Res Ther 6:3-9. 2011
    ..In this review we reviewed the current views of the cellular mechanisms that lay beneath disease induction of JIA and the disease remission caused by aBMT therapy...
  9. ncbi request reprint Autologous stem cell transplantation for autoimmunity induces immunologic self-tolerance by reprogramming autoreactive T cells and restoring the CD4+CD25+ immune regulatory network
    Isme de Kleer
    University Medical Center Utrecht, Wilhelmina Children s Hospital, Home Mailbox KC 03 063 0, Department of Pediatric Immunology, PO Box 85090, 3508 AB Utrecht, The Netherlands
    Blood 107:1696-702. 2006
    ....
  10. ncbi request reprint Refractory juvenile idiopathic arthritis: using autologous stem cell transplantation as a treatment strategy
    Nico M Wulffraat
    Department of Pediatric Immunology, University Medical Center Utrecht, Wilhelmina Children s Hospital, 3508 AB Utrecht, The Netherlands
    Expert Rev Mol Med 8:1-11. 2006
    ..This review describes the clinical results of ASCT performed for this disease and the possible underlying immunological mechanisms...
  11. doi request reprint Cytokine multiplex immunoassay: methodology and (clinical) applications
    Wilco de Jager
    Department of Pediatric Immunology, Wilhelmina Children s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
    Methods Mol Biol 514:119-33. 2009
    ..The power and robustness of the MIA technique is illustrated by an analysis of cytokine profiles in juvenile idiopathic arthritis...
  12. doi request reprint Juvenile idiopathic arthritis
    Berent Prakken
    Centre for Molecular and Cellular Intervention, Department of Paediatrics, University Medical Centre Utrecht, Netherlands
    Lancet 377:2138-49. 2011
    ..Altogether these new developments in genetics, immunology, and imaging are instrumental to better define, classify, and treat patients with juvenile idiopathic arthritis...
  13. ncbi request reprint Heat shock proteins in juvenile idiopathic arthritis: keys for understanding remitting arthritis and candidate antigens for immune therapy
    Berent Prakken
    Department of Pediatric Immunology, University Medical Center Utrecht, University Hospital for Children and Youth, PO Box 85090, Utrecht 3508 AB, The Netherlands
    Curr Rheumatol Rep 4:466-73. 2002
    ..Taken together, these data imply that immune modulation with hsps can be an effective way to restore natural occurring T cell responses, and, thus, treat JIA and rheumatoid arthritis...
  14. doi request reprint Vaccination leads to an aberrant FOXP3 T-cell response in non-remitting juvenile idiopathic arthritis
    Arash Ronaghy
    Department of Pediatrics, Center for Cellular and Molecular Intervention, Wilhelmina Children s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
    Ann Rheum Dis 70:2037-43. 2011
    ....