H Karst

Summary

Affiliation: University of Amsterdam
Country: The Netherlands

Publications

  1. ncbi request reprint Episodic corticosterone treatment accelerates kindling epileptogenesis and triggers long-term changes in hippocampal CA1 cells, in the fully kindled state
    H Karst
    Department of Exp Zoology, University of Amsterdam, Kruislaan 320, 1098 SM Amsterdam, The Netherlands
    Eur J Neurosci 11:889-98. 1999
  2. ncbi request reprint Acute stress increases calcium current amplitude in rat hippocampus: temporal changes in physiology and gene expression
    M Joels
    Swammerdam Institute for Life Sciences, University of Amsterdam, Kruislaan 320, 1098 SM Amsterdam, The Netherlands
    Eur J Neurosci 18:1315-24. 2003
  3. ncbi request reprint Corticosteroid actions in hippocampus require DNA binding of glucocorticoid receptor homodimers
    H Karst
    Inst Neurobiology, University of Amsterdam, Kruislaan 320, 1098 SM Amsterdam, The Netherlands
    Nat Neurosci 3:977-8. 2000
  4. doi request reprint Rapid changes in hippocampal CA1 pyramidal cell function via pre- as well as postsynaptic membrane mineralocorticoid receptors
    J E Olijslagers
    SILS CNS, University of Amsterdam, Kruislaan 320, 1098 SM Amsterdam, The Netherlands
    Eur J Neurosci 27:2542-50. 2008
  5. ncbi request reprint Calcium currents in rat dentate granule cells are altered after adrenalectomy
    H Karst
    Swammerdam Institute for Life Sciences, University of Amsterdam, Kruislaan 320, 1098 SM Amsterdam, The Netherlands
    Eur J Neurosci 14:503-12. 2001
  6. ncbi request reprint Opposite effects of glucocorticoid receptor activation on hippocampal CA1 dendritic complexity in chronically stressed and handled animals
    D N Alfarez
    Swammerdam Institute for Life Sciences, Center for Neuroscience, Universiteit van Amsterdam, Kruislaan 320, 1098 SM, Amsterdam, The Netherlands
    Hippocampus 18:20-8. 2008
  7. ncbi request reprint Morphological and functional properties of rat dentate granule cells after adrenalectomy
    J Wossink
    Swammerdam Institute of Life Sciences, University of Amsterdam, Kruislaan 320, 1098 SM Amsterdam, The Netherlands
    Neuroscience 108:263-72. 2001
  8. ncbi request reprint Hippocampal cell responses in mice with a targeted glucocorticoid receptor gene disruption
    W Hesen
    Department of Experimental Zoology, University of Amsterdam, 1098 SM Amsterdam, The Netherlands
    J Neurosci 16:6766-74. 1996

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Episodic corticosterone treatment accelerates kindling epileptogenesis and triggers long-term changes in hippocampal CA1 cells, in the fully kindled state
    H Karst
    Department of Exp Zoology, University of Amsterdam, Kruislaan 320, 1098 SM Amsterdam, The Netherlands
    Eur J Neurosci 11:889-98. 1999
    ....
  2. ncbi request reprint Acute stress increases calcium current amplitude in rat hippocampus: temporal changes in physiology and gene expression
    M Joels
    Swammerdam Institute for Life Sciences, University of Amsterdam, Kruislaan 320, 1098 SM Amsterdam, The Netherlands
    Eur J Neurosci 18:1315-24. 2003
    ..Prior to the functional change, increased expression of calcium channel subunits was observed, suggesting that the enhanced function could be explained by transcriptional regulation of the channels...
  3. ncbi request reprint Corticosteroid actions in hippocampus require DNA binding of glucocorticoid receptor homodimers
    H Karst
    Inst Neurobiology, University of Amsterdam, Kruislaan 320, 1098 SM Amsterdam, The Netherlands
    Nat Neurosci 3:977-8. 2000
    ..Here we show that at least some of these actions require DNA binding of glucocorticoid receptor (GR) homodimers...
  4. doi request reprint Rapid changes in hippocampal CA1 pyramidal cell function via pre- as well as postsynaptic membrane mineralocorticoid receptors
    J E Olijslagers
    SILS CNS, University of Amsterdam, Kruislaan 320, 1098 SM Amsterdam, The Netherlands
    Eur J Neurosci 27:2542-50. 2008
    ..Through these dual pathways, high corticosterone concentrations such as occur after stress could contribute to enhanced CA1 pyramidal excitability...
  5. ncbi request reprint Calcium currents in rat dentate granule cells are altered after adrenalectomy
    H Karst
    Swammerdam Institute for Life Sciences, University of Amsterdam, Kruislaan 320, 1098 SM Amsterdam, The Netherlands
    Eur J Neurosci 14:503-12. 2001
    ..The data indicate that cellular calcium current characteristics of dentate granule cells are altered after adrenalectomy and that the alterations may in part determine the vulnerability to undergo apoptosis...
  6. ncbi request reprint Opposite effects of glucocorticoid receptor activation on hippocampal CA1 dendritic complexity in chronically stressed and handled animals
    D N Alfarez
    Swammerdam Institute for Life Sciences, Center for Neuroscience, Universiteit van Amsterdam, Kruislaan 320, 1098 SM, Amsterdam, The Netherlands
    Hippocampus 18:20-8. 2008
    ....
  7. ncbi request reprint Morphological and functional properties of rat dentate granule cells after adrenalectomy
    J Wossink
    Swammerdam Institute of Life Sciences, University of Amsterdam, Kruislaan 320, 1098 SM Amsterdam, The Netherlands
    Neuroscience 108:263-72. 2001
    ..Our data indicate that in the absence of corticosterone dendritic trees of dentate granule cells display atrophy but that this does not necessarily reduce ionic currents measured in the soma...
  8. ncbi request reprint Hippocampal cell responses in mice with a targeted glucocorticoid receptor gene disruption
    W Hesen
    Department of Experimental Zoology, University of Amsterdam, 1098 SM Amsterdam, The Netherlands
    J Neurosci 16:6766-74. 1996
    ..These findings exemplify the use of GR knockout mice for the study of cellular properties in the brain. Further substantiation of the observations, however, awaits the development of site-specific, inducible GR knockouts...