University Medical Center Utrecht

Summary

Organization: University Medical Center Utrecht
Country: The Netherlands

Top Publications

  1. ncbi [The Dutch MRSA policy can and should be different]
    Marjan W M Wassenberg
    Universitair Medisch Centrum, Afd Medische Microbiologie, Utrecht, The Netherlands
    Ned Tijdschr Geneeskd 154:A2575. 2010
  2. doi L-serine synthesis in the central nervous system: a review on serine deficiency disorders
    L Tabatabaie
    Department of Metabolic and Endocrine Diseases, University Medical Center Utrecht and Netherlands Metabolomics Centre, The Netherlands
    Mol Genet Metab 99:256-62. 2010
  3. doi Using hierarchical dynamic Bayesian networks to investigate dynamics of organ failure in patients in the Intensive Care Unit
    Linda Peelen
    Department of Medical Informatics, Academic Medical Center, Amsterdam, The Netherlands
    J Biomed Inform 43:273-86. 2010
  4. doi Low bone mineral density in adult patients with moderate to severe atopic dermatitis
    I M Haeck
    Department of Dermatology and Allergology, University Medical Center Utrecht, Inhouse postnumber G02 124, Utrecht, The Netherlands
    Br J Dermatol 161:1248-54. 2009
  5. doi State of the art: implantable ventricular assist devices
    J R Lahpor
    Department of Heart and Lung, University Medical Center, Utrecht, The Netherlands
    Curr Opin Organ Transplant 14:554-9. 2009
  6. pmc Is there a role for CT coronary angiography in patients with symptomatic angina? Effect of coronary calcium score on identification of stenosis
    Matthijs F L Meijs
    Department of Cardiology, Utrecht University Medical Center, Heidelberglaan 100, Utrecht, The Netherlands
    Int J Cardiovasc Imaging 25:847-54. 2009
  7. doi Array analysis and karyotyping: workflow consequences based on a retrospective study of 36,325 patients with idiopathic developmental delay in the Netherlands
    Ron Hochstenbach
    Department of Biomedical Genetics, University Medical Centre Utrecht, P O Box 85090, 3508 AB Utrecht, The Netherlands
    Eur J Med Genet 52:161-9. 2009
  8. doi Cost-effectiveness of preventive treatment of intracranial aneurysms: new data and uncertainties
    Jacoba P Greving
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85500, 3508 GA Utrecht, The Netherlands
    Neurology 73:258-65. 2009
  9. doi Heritability of regional and global brain structure at the onset of puberty: a magnetic resonance imaging study in 9-year-old twin pairs
    Jiska S Peper
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center, Utrecht, The Netherlands
    Hum Brain Mapp 30:2184-96. 2009
  10. doi Behavior and development in children and age at the time of first anesthetic exposure
    Cor J Kalkman
    Department of Anesthesiology, University Medical Center, Utrecht, The Netherlands
    Anesthesiology 110:805-12. 2009

Research Grants

Detail Information

Publications62

  1. ncbi [The Dutch MRSA policy can and should be different]
    Marjan W M Wassenberg
    Universitair Medisch Centrum, Afd Medische Microbiologie, Utrecht, The Netherlands
    Ned Tijdschr Geneeskd 154:A2575. 2010
    ..When rapid tests are performed, in addition to conventional cultures, patients at risk no longer need to be isolated and the closure of wards due to the risk of an outbreak is no longer necessary...
  2. doi L-serine synthesis in the central nervous system: a review on serine deficiency disorders
    L Tabatabaie
    Department of Metabolic and Endocrine Diseases, University Medical Center Utrecht and Netherlands Metabolomics Centre, The Netherlands
    Mol Genet Metab 99:256-62. 2010
    ..In this review, we will discuss the cellular functions of the L-serine pathway, structure and enzymatic properties of the enzymes involved and genetic defects associated with this pathway...
  3. doi Using hierarchical dynamic Bayesian networks to investigate dynamics of organ failure in patients in the Intensive Care Unit
    Linda Peelen
    Department of Medical Informatics, Academic Medical Center, Amsterdam, The Netherlands
    J Biomed Inform 43:273-86. 2010
    ..We demonstrate the induction, inference, evaluation, and use of these models in practice in a case-study of patients with severe sepsis admitted to four Dutch ICUs...
  4. doi Low bone mineral density in adult patients with moderate to severe atopic dermatitis
    I M Haeck
    Department of Dermatology and Allergology, University Medical Center Utrecht, Inhouse postnumber G02 124, Utrecht, The Netherlands
    Br J Dermatol 161:1248-54. 2009
    ..Atopic dermatitis (AD) is a chronic inflammatory skin disease commonly treated with topical corticosteroids. The inflammatory nature of this disorder and the use of topical corticosteroids represent potential risk factors for bone loss...
  5. doi State of the art: implantable ventricular assist devices
    J R Lahpor
    Department of Heart and Lung, University Medical Center, Utrecht, The Netherlands
    Curr Opin Organ Transplant 14:554-9. 2009
    ..Newer second generation of nonpulsatile VADs shows less of such limitations...
  6. pmc Is there a role for CT coronary angiography in patients with symptomatic angina? Effect of coronary calcium score on identification of stenosis
    Matthijs F L Meijs
    Department of Cardiology, Utrecht University Medical Center, Heidelberglaan 100, Utrecht, The Netherlands
    Int J Cardiovasc Imaging 25:847-54. 2009
    ..In patients with CS <10, CTCA provides excellent diagnostic performance...
  7. doi Array analysis and karyotyping: workflow consequences based on a retrospective study of 36,325 patients with idiopathic developmental delay in the Netherlands
    Ron Hochstenbach
    Department of Biomedical Genetics, University Medical Centre Utrecht, P O Box 85090, 3508 AB Utrecht, The Netherlands
    Eur J Med Genet 52:161-9. 2009
    ..78% of all DD/MR referrals...
  8. doi Cost-effectiveness of preventive treatment of intracranial aneurysms: new data and uncertainties
    Jacoba P Greving
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85500, 3508 GA Utrecht, The Netherlands
    Neurology 73:258-65. 2009
    ....
  9. doi Heritability of regional and global brain structure at the onset of puberty: a magnetic resonance imaging study in 9-year-old twin pairs
    Jiska S Peper
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center, Utrecht, The Netherlands
    Hum Brain Mapp 30:2184-96. 2009
    ..Pubertal development may be directly involved in the decreases in gray matter areas that accompany the transition of our brains from childhood into adulthood...
  10. doi Behavior and development in children and age at the time of first anesthetic exposure
    Cor J Kalkman
    Department of Anesthesiology, University Medical Center, Utrecht, The Netherlands
    Anesthesiology 110:805-12. 2009
    ..Pediatric urological procedures were selected because the timing of surgery depends mainly on the age at which a diagnosis is made...
  11. doi Do pressure ulcers influence length of hospital stay in surgical cardiothoracic patients? A prospective evaluation
    Jaap Peter Schuurman
    St Antonius Hospital, PO Box 2500, 3430 EM, Nieuwegein, The Netherlands
    J Clin Nurs 18:2456-63. 2009
    ..The aim and objective of this study was to determine whether the occurrence of pressure ulcers following cardiothoracic surgery increases the length of hospitalisation...
  12. ncbi [Symptomatic treatment in patients with dementia: light, but not melatonin, is probably worthwhile]
    R J van Marum
    Universitair Medisch Centrum Utrecht, Afd Geriatrie, Postbus 85 500, 3508 GA Utrecht
    Ned Tijdschr Geneeskd 152:2322-4. 2008
    ..Increasing light intensity in the living rooms of patients with dementia is an easy and cheap intervention with possible positive effects on at least some patients...
  13. doi Staphylococcal SSL5 inhibits leukocyte activation by chemokines and anaphylatoxins
    Jovanka Bestebroer
    Medical Microbiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Blood 113:328-37. 2009
    ..It is therefore a potential new antiinflammatory compound for diseases associated with chemoattractants and their receptors and disorders characterized by excessive recruitment of leukocytes...
  14. doi Carotid atherosclerotic plaques stabilize after stroke: insights into the natural process of atherosclerotic plaque stabilization
    W Peeters
    Experimental Cardiology Laboratory, University Medical Centre Utrecht, Utrecht, The Netherlands
    Arterioscler Thromb Vasc Biol 29:128-33. 2009
    ..Underlying cellular and molecular characteristics of plaque rupture have been studied extensively. However, the natural course of symptomatic plaque remodeling after ischemic events is relatively unexplored...
  15. doi A comparison of dose-response models for the parotid gland in a large group of head-and-neck cancer patients
    Antonetta C Houweling
    Department of Radiotherapy, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Int J Radiat Oncol Biol Phys 76:1259-65. 2010
    ..However, various other normal tissue complication probability (NTCP) models exist. We evaluated in a large group of patients the value of six NTCP models that describe the parotid gland dose response 1 year after radiotherapy...
  16. doi The digital eczema centre utrecht
    Harmieke van Os-Medendorp
    Dermatology Allergology Department, UMC Utrecht, The Netherlands
    J Telemed Telecare 16:12-4. 2010
    ..The web-based patient record and the digital chain-of-care promote the involvement of patients, parents and multidisciplinary teams as well as the continuity and coordination of care...
  17. ncbi [Risk of infection due to contamination of medicines]
    P C W Willem Meulenhoff
    Universitair Medisch Centrum Utrecht, Apotheek, Divisie Laboratoria en Apotheek, Utrecht, The Neterlands
    Ned Tijdschr Geneeskd 154:A1723. 2010
    ..To enhance patient safety it is important to identify the separate steps that are the most prone to error, based on a good risk analysis. A systematic and coordinated approach is crucial for success in this process...
  18. doi Klinefelter syndrome: clinical and molecular aspects
    Jacques C Giltay
    University Medical Centre Utrecht, Department of Medical Genetics, Utrecht, The Netherlands
    Expert Rev Mol Diagn 10:765-76. 2010
    ..Surgical procedures of obtaining sperm in combination with repeated intracytoplasmic sperm injection/in vitro fertilization treatment may allow up to one in four men with Klinefelter syndrome to father children...
  19. doi Glycemic variability in inadequately controlled type 1 diabetes and type 2 diabetes on intensive insulin therapy: a cross-sectional, observational study
    Wendela L Greven
    Department of Internal Medicine, University Medical Centre Utrecht, The Netherlands
    Diabetes Technol Ther 12:695-9. 2010
    ..Therefore in this study we investigate different parameters of glycemic variability and differences between T1DM and T2DM in inadequately controlled patients on intensive insulin treatment...
  20. doi Variations in treatment policies and outcome for bladder cancer in the Netherlands
    C A Goossens-Laan
    Department of Urology, Utrecht University Medical Center affiliated with St Elisabeth Hospital, Department of Urology, Utrecht, The Netherlands
    Eur J Surg Oncol 36:S100-7. 2010
    ..To describe the population-based variation in treatment policies and outcome for bladder cancer in the Netherlands...
  21. doi Is bacterial vaginosis associated with a pro-inflammatory cytokine profile in endometrial secretions of women undergoing IVF?
    Carolien M Boomsma
    Department of Reproductive Medicine and Gynecology, University Medical Centre Utrecht, P O Box 85500, 3508 GA Utrecht, The Netherlands
    Reprod Biomed Online 21:133-41. 2010
    ..However, no distinct difference in pro- and anti-inflammatory profiles is present. An effect on endometrial receptivity is unlikely...
  22. doi Orphan granzymes find a home
    Niels Bovenschen
    Department of Pathology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands
    Immunol Rev 235:117-27. 2010
    ..In this review, we summarize and discuss what is currently known about the biology of the human orphan granzymes...
  23. doi Low treatment adherence with antipsychotics is associated with relapse in psychotic disorders within six months after discharge
    W Laan
    Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands
    Pharmacopsychiatry 43:221-4. 2010
    ..The aim of this study was to assess the association between treatment adherence with antipsychotics and schizophrenia relapse on a continuous scale...
  24. ncbi [Detection of metabolic syndrome by self-measurement of waist circumference]
    Corine den Engelsen
    Universitair Medisch Centrum Utrecht, divisie Julius Centrum voor Gezondheidswetenschappen en Eerstelijnsgeneeskunde, afd Huisartsgeneeskunde, Utrecht, The Netherlands
    Ned Tijdschr Geneeskd 154:A1028. 2010
    ..We also investigated the prevalence of metabolic syndrome in a population of patients aged 20-69 years in IJsselstein, the Netherlands...
  25. doi Vertical integration in medical school: effect on the transition to postgraduate training
    Marjo Wijnen-Meijer
    Centre for Research and Development of Education, University Medical Centre Utrecht, Research and Development of Education, HB 4 05, PO Box 85500, 3508 GA Utrecht, The Netherlands
    Med Educ 44:272-9. 2010
    ..The purpose of the present study is to determine whether a VI curriculum at medical school affects the transition to postgraduate training in a positive way...
  26. doi Male gender and poor visual outcome in uveitis associated with juvenile idiopathic arthritis
    Viera Kalinina Ayuso
    Department of Ophthalmology, University Medical Centre Utrecht, Utrecht, The Netherlands
    Am J Ophthalmol 149:987-93. 2010
    ..To analyze visual outcome in uveitis associated with juvenile idiopathic arthritis (JIA) according to age of onset of uveitis, gender, and initial manifestation of JIA...
  27. doi Vasomotor symptoms, estradiol levels and cardiovascular risk profile in women
    Gerrie Cor M Gast
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
    Maturitas 66:285-90. 2010
    ..Furthermore, we examined the association between estradiol levels and VMS, and whether an association between VMS and cardiovascular risk factors can be explained by estradiol levels...
  28. pmc Can animal models of disease reliably inform human studies?
    H Bart van der Worp
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
    PLoS Med 7:e1000245. 2010
    ..H. Bart van der Worp and colleagues discuss the controversies and possibilities of translating the results of animal experiments into human clinical trials...
  29. pmc Screening for proximal coronary artery anomalies with 3-dimensional MR coronary angiography
    Niek H Prakken
    Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, The Netherlands
    Int J Cardiovasc Imaging 26:701-10. 2010
    ..This also enabled faster scan sequences. A 3D-MRCA can be used as part of the standard cardiac MRI protocol to screen young competitive athletes and non-athletes for anomalous proximal coronary arteries...
  30. doi The relationship between children with voiding problems and their parents
    J Labrie
    Department of Perinatology and Gynecology, University Children s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
    J Urol 183:1887-91. 2010
    ..We determined whether parents of children with overactive bladder and dysfunctional voiding had had similar symptoms in childhood...
  31. doi Unilateral intracarotid injection of holmium microspheres to induce bilateral MRI-validated cerebral embolization in rats
    Fellery de Lange
    Division of Perioperative Care and Emergency Medicine, University Medical Center Utrecht, Mail Stop, 3508 GA Utrecht, The Netherlands
    J Neurosci Methods 176:152-6. 2009
    ..We have developed a model for bilateral cerebral micro-embolization. By using holmium microspheres, it is possible to quantify intracerebral delivery using MRI...
  32. pmc Proline affects brain function in 22q11DS children with the low activity COMT 158 allele
    Jacob A S Vorstman
    Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    Neuropsychopharmacology 34:739-46. 2009
    ..22q11DS patients with low dopamine catabolic capacity are therefore especially vulnerable to this functional disruption...
  33. pmc Duhamel procedure: a comparative retrospective study between an open and a laparoscopic technique
    D Vieira Travassos
    Department of Pediatric Surgery, Wilhelmina Children s Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands
    Surg Endosc 21:2163-5. 2007
    ..Few studies are available comparing open with laparoscopic treatment of Hirschsprung's disease. This study compares a laparoscopic series of 30 patients with a historical open series of 25 patients...
  34. pmc Appreciation of the informed consent procedure in a randomised trial of decompressive surgery for space occupying hemispheric infarction
    J Hofmeijer
    Department of Neurology, C03 236, University Medical Centre Utrecht, PO Box 85500, 3508 GA Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 78:1124-8. 2007
    ....
  35. ncbi Cognitive and cardiac outcomes 5 years after off-pump vs on-pump coronary artery bypass graft surgery
    Diederik van Dijk
    Department of Anesthesiology, University Medical Center Utrecht, Utrecht, The Netherlands
    JAMA 297:701-8. 2007
    ..The effect of avoiding cardiopulmonary bypass (off-pump CABG) on long-term cognitive and cardiac outcomes is unknown...
  36. ncbi Elevated plasma arginine vasopressin levels in veterans with posttraumatic stress disorder
    C S de Kloet
    Department of Military Psychiatry, Central Military Hospital, Magnus Institute of Neuroscience, Utrecht, The Netherlands
    J Psychiatr Res 42:192-8. 2008
    ..In order to evaluate the effect of trauma and PTSD on central AVP secretion we assessed plasma AVP levels in equally trauma exposed veterans with and without PTSD and a non-traumatized healthy control group...
  37. pmc Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE
    Marc Vooijs
    Department of Molecular Biology and Pharmacology and the Department of Medicine, Division of Dermatology, Washington University Medical School, St Louis, MO 63110, USA
    Development 134:535-44. 2007
    ..These findings highlight an underappreciated layer of complexity of Notch signaling in vivo. Moreover, NIP-CRE represents a general strategy applicable for monitoring proteolysis-dependent signaling in vivo...
  38. ncbi Physical activity and breast cancer: a systematic review
    Evelyn M Monninkhof
    University Medical Center Utrecht, Julius Center for Health Sciences and Primary Care, Utrecht, The Netherlands
    Epidemiology 18:137-57. 2007
    ..Many epidemiologic studies have found an association between physical activity and breast cancer risk, although this has not been a consistent finding...
  39. ncbi Describing computed tomography findings in acute necrotizing pancreatitis with the Atlanta classification: an interobserver agreement study
    Marc G H Besselink
    Department of Surgery, University Medical Center Utrecht, The Netherlands
    Pancreas 33:331-5. 2006
    ..A study was undertaken to assess the interobserver agreement of categorizing peripancreatic collections on computed tomography (CT) using the Atlanta classification...
  40. pmc Trust, competence, and the supervisor's role in postgraduate training
    Olle ten Cate
    Centre for Research and Development of Education, University Medical Centre Utrecht, PO Box 85500, 3508 GA Utrecht, Netherlands
    BMJ 333:748-51. 2006
  41. ncbi Indwelling balloon dilatation for esophageal stenosis in infants
    David C van der Zee
    Department of Pediatric Surgery, University Medical Center, Utrecht, The Netherlands
    J Pediatr Gastroenterol Nutr 42:437-9. 2006
  42. ncbi Determinants of functional independence and quality of life in children with spina bifida
    M A G C Schoenmakers
    Department of Paediatric Physiotherapy, Room KB 02 056 0, Wilhelmina Children s Hospital, University Medical Centre, Utrecht, P O Box 85090, 3508 AB Utrecht, The Netherlands
    Clin Rehabil 19:677-85. 2005
    ..To investigate determinants of functional independence and study which functional abilities were determinants for 'health-related quality of life' in children with myelomeningocele...
  43. ncbi Disease modifying genes in cystic fibrosis
    Martijn G Slieker
    Cystic Fibrosis Center Utrecht, University Medical Center Utrecht, P O Box 85090, 3508AB Utrecht, The Netherlands
    J Cyst Fibros 4:7-13. 2005
    ..Identification of genetic variation in modifier genes, obtained by genotype-phenotype studies in well-defined patient populations, may be used as an aid to prognosis and may provide the possibility of new therapeutic interventions...
  44. ncbi Viral respiratory infections in cystic fibrosis
    Bart E van Ewijk
    Cystic Fibrosis Centre and Department of Paediatric Respiratory Medicine, Wilhelmina Children s Hospital University Medical Centre, P O Box 85090, 3508 AB Utrecht, The Netherlands
    J Cyst Fibros 4:31-6. 2005
    ..Further knowledge about the role of viruses and interaction with bacteria in CF lung disease might result in new therapeutic strategies to improve prognosis of CF patients...
  45. ncbi Negative attitude of highly educated parents and health care workers towards future vaccinations in the Dutch childhood vaccination program
    E Hak
    University Medical Center Utrecht, Julius Center for Health Sciences and Primary Health Care, HP Str 6 131, P O Box 85060, 3508 AB Utrecht, The Netherlands
    Vaccine 23:3103-7. 2005
    ..It is unknown whether further expansion of the Dutch childhood vaccination program with other vaccines will be accepted and whom should be targeted in educational strategies...
  46. ncbi Confounding in publications of observational intervention studies
    Rolf H H Groenwold
    Julius Center for Health Sciences and Primary Care, University Medical Center, Universiteitsweg 100, STR 6 118, 3584 GC, Utrecht, The Netherlands
    Eur J Epidemiol 22:413-5. 2007
    ..This study shows only 9% of all papers on observational intervention studies published in peer-reviewed medical journals mention any of the terms (confounding, adjustment, or bias) indicating appreciation of confounding...
  47. ncbi Stem cell transplantation nephropathy: a report of six cases
    Sabina Kersting
    Department of Hematology, University Medical Center Utrecht, Utrecht, The Netherlands
    Biol Blood Marrow Transplant 13:638-43. 2007
    ..All patients had TBI with shielding of the kidneys. We discuss the course of the syndrome, treatment, and outcome of the patients...
  48. ncbi Concomitant functional dyspepsia and irritable bowel syndrome decrease health-related quality of life in gastroesophageal reflux disease
    Durk R De Vries
    Department of Gastroenterology, University Medical Center, Utrecht, The Netherlands
    Scand J Gastroenterol 42:951-6. 2007
    ..The aim of this study was to investigate the prevalence of FD and IBS in gastroesophageal reflux disease (GERD) and the effect on health-related quality of life (HRQoL)...
  49. ncbi Extremes in vitamin K status of bone are related to bone ultrasound properties in children with juvenile idiopathic arthritis
    M J H van Summeren
    Department of Paediatric Immunology, University Medical Centre Utrecht, The Netherlands
    Clin Exp Rheumatol 26:484-91. 2008
    ..We studied the vitamin K status of bone and its association with bone mass properties in children with JIA compared to healthy children...
  50. doi Why do couples drop-out from IVF treatment? A prospective cohort study
    M F G Verberg
    Department of Reproductive Medicine and Gynaecology, University Medical Centre Utrecht, Heidelberglaan 100, 3584 CS Utrecht, The Netherlands
    Hum Reprod 23:2050-5. 2008
    ..The aim of this study was to identify the role of the treatment strategy applied, and potential other factors that influence the decision of couples to discontinue treatment...
  51. doi Schizophrenia as a progressive brain disease
    N E M Van Haren
    Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Centre Utrecht, Heidelberglaan 100, Utrecht, The Netherlands
    Eur Psychiatry 23:245-54. 2008
    ..One of the main challenges for the coming years, however, will be the search for gene-by-environment interactions on the progressive brain changes in schizophrenia...
  52. ncbi [Echographic screening of the abdominal aorta in older men is not useful]
    Y van der Graaf
    Universitair Medisch Centrum Utrecht, Julius Centrum voor Gezondheidswetenschappen en Eerstelijns Geneeskunde, Huispost STR 6 131, Postbus 85 500, 3508 GA Utrecht
    Ned Tijdschr Geneeskd 152:751. 2008
    ..The result of screening is that many men (5%) are medicalised unjustly and exposed to the severe risks of a surgical intervention. The mortality during open surgery is 5-6%. Screening has no effect on the total mortality...
  53. doi Psychosocial functioning of spouses in the chronic phase after stroke: improvement or deterioration between 1 and 3 years after stroke?
    Anne Visser-Meily
    Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht and Rehabilitation Center De Hoogstraat, Utrecht, The Netherlands
    Patient Educ Couns 73:153-8. 2008
    ..To describe the psychosocial functioning of spouses of stroke patients at 1 and 3 years after stroke and identify predictors of substantial negative change in psychosocial functioning...
  54. doi Alterations in serotonin signalling are involved in the hyperactivity of Pitx3-deficient mice
    Simone M Smits
    Rudolf Magnus Institute of Neuroscience, Department of Neuroscience and Pharmacology, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands
    Eur J Neurosci 27:388-95. 2008
    ..Taken together, our results indicate alterations in 5-HT signalling in Pitx3-deficient mice that underlie their spontaneous hyperactivity...
  55. ncbi Coronary calcification: effect of small variation of scan starting position on Agatston, volume, and mass scores
    Annemarieke Rutten
    Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, Room E01 132, 3584 CX Utrecht, The Netherlands
    Radiology 246:90-8. 2008
    ..To retrospectively evaluate the effect of a small variation of scan starting position on coronary artery calcium scores based on nonoverlapping 3-mm multidetector computed tomographic (CT) data sets...
  56. ncbi Postoperative high-dose-rate brachytherapy in the prevention of keloids
    Ronald E Veen
    Department of Radiotherapy, University Medical Center, Utrecht, The Netherlands
    Int J Radiat Oncol Biol Phys 69:1205-8. 2007
    ..The aim of this study is to show the efficiency of keloidectomy and postoperative interstitial high-dose-rate (HDR) brachytherapy in the prevention of keloids...
  57. ncbi No increased incidence of diabetes in antidepressant users
    Mirjam J Knol
    Julius Center for Health Sciences and Primary Care, Utrecht, The Netherlands
    Int Clin Psychopharmacol 22:382-6. 2007
    ..12-1.68) for AD and BD users compared with no AD and no BD users. We did not find an increased risk of diabetes in individuals using ADs. The association between BD use and diabetes was partly explained by chronic somatic comorbidity...
  58. ncbi Assessing quality of nursing care as a confounding variable in an outcome study on neurodevelopmental treatment
    Thóra B Hafsteinsdottir
    Division of Neurosciences, Rudolph Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Nurs Care Qual 22:371-7. 2007
    ..49). This method may be useful to other researchers conducting outcome research and who are confronted with a similar methodological problem...
  59. pmc Five genes encoding surface-exposed LPXTG proteins are enriched in hospital-adapted Enterococcus faecium clonal complex 17 isolates
    Antoni P A Hendrickx
    Department of Medical Microbiology, University Medical Center Utrecht, Heidelberglaan 100, Rm G04 614, 3584 CX Utrecht, The Netherlands
    J Bacteriol 189:8321-32. 2007
    ....
  60. ncbi Computed tomography of the coronary arteries: an alternative?
    Matthijs F L Meijs
    Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Scand Cardiovasc J 41:277-86. 2007
    ..Although CTCA has clearly left the research environment, the precise role of CTCA in the diagnostic work-up of coronary artery disease needs further research...
  61. ncbi Radionuclide liver cancer therapies: from concept to current clinical status
    Maarten A D Vente
    Department of Nuclear Medicine, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, The Netherlands
    Anticancer Agents Med Chem 7:441-59. 2007
    ..Since (166)Ho is a combined beta-gamma emitter and highly paramagnetic as well, it allows for both (quantitative) scintigraphic and magnetic resonance imaging...
  62. ncbi Tailor-made pharmacotherapy: future developments and ethical challenges in the field of pharmacogenomics
    Johannes van Delden
    Julius Center for Health Sciences, University Medical Center Utrecht, HP Str 6 131, PO Box 85500, 3508 GA Utrecht, The Netherlands
    Bioethics 18:303-21. 2004
    ..We suggest that the notion of 'responsibility' will be a major focus of such research...

Research Grants3