Mark Potse

Summary

Affiliation: Research Center
Country: The Netherlands

Publications

  1. doi P-wave complexity in normal subjects and computer models
    Mark Potse
    Department of Biomedical Engineering, Cardiovascular Research Institute Maastricht, Maastricht University, Universiteitssingel 50, 6229 ER Maastricht, The Netherlands Electronic address
    J Electrocardiol 49:545-53. 2016
  2. pmc Patient-specific modelling of cardiac electrophysiology in heart-failure patients
    Mark Potse
    Center for Computational Medicine in Cardiology, Faculty of Informatics, Università della Svizzera italiana, Via Giuseppe Buffi 13, 6904 Lugano, Switzerland Inria Bordeaux Sud Ouest, 33405 Talence Cedex, France
    Europace 16:iv56-iv61. 2014
  3. doi Similarities and differences between electrocardiogram signs of left bundle-branch block and left-ventricular uncoupling
    Mark Potse
    Institute of Computational Science, Faculty of Informatics, Università della Svizzera italiana, Via Giuseppe Buffi 13, Lugano, Switzerland
    Europace 14:v33-v39. 2012
  4. pmc Mathematical modeling and simulation of ventricular activation sequences: implications for cardiac resynchronization therapy
    Mark Potse
    Institute of Computational Science, University of Lugano, Via Giuseppe Buffi 13, 6904 Lugano, Switzerland
    J Cardiovasc Transl Res 5:146-58. 2012
  5. pmc Cardiac anisotropy in boundary-element models for the electrocardiogram
    Mark Potse
    Research Center, Sacre Coeur Hospital, 5400 Boulevard Gouin Ouest, Montreal, QC, H4J 1C5, Canada
    Med Biol Eng Comput 47:719-29. 2009
  6. doi Validation of a simple model for the morphology of the T wave in unipolar electrograms
    Mark Potse
    Institute of Biomedical Engineering, Universite de Montreal, Montreal, Quebec, Canada
    Am J Physiol Heart Circ Physiol 297:H792-801. 2009
  7. ncbi The role of extracellular potassium transport in computer models of the ischemic zone
    Mark Potse
    Research Center, Sacre Coeur Hospital, 5400 Boulevard Gouin Ouest, Montreal, QC, Canada, H4J 1C5
    Med Biol Eng Comput 45:1187-99. 2007
  8. ncbi ST elevation or depression in subendocardial ischemia?
    Mark Potse
    Res Center, Hosp du Sacre Coeur de Montreal, Que
    Conf Proc IEEE Eng Med Biol Soc 1:3899-902. 2006
  9. ncbi A comparison of monodomain and bidomain propagation models for the human heart
    Mark Potse
    Res Center, Hosp du Sacre Coeur de Montreal, Que
    Conf Proc IEEE Eng Med Biol Soc 1:3895-8. 2006
  10. ncbi The positive T wave
    Mark Potse
    Department of Physiology, Institute of Biomedical Engineering, Universite de Montreal, Montreal, Quebec, Canada
    Anadolu Kardiyol Derg 7:164-7. 2007

Detail Information

Publications30

  1. doi P-wave complexity in normal subjects and computer models
    Mark Potse
    Department of Biomedical Engineering, Cardiovascular Research Institute Maastricht, Maastricht University, Universiteitssingel 50, 6229 ER Maastricht, The Netherlands Electronic address
    J Electrocardiol 49:545-53. 2016
    ..P waves reported in electrocardiology literature uniformly appear smooth. Computer simulation and signal analysis studies have shown much more complex shapes...
  2. pmc Patient-specific modelling of cardiac electrophysiology in heart-failure patients
    Mark Potse
    Center for Computational Medicine in Cardiology, Faculty of Informatics, Università della Svizzera italiana, Via Giuseppe Buffi 13, 6904 Lugano, Switzerland Inria Bordeaux Sud Ouest, 33405 Talence Cedex, France
    Europace 16:iv56-iv61. 2014
    ....
  3. doi Similarities and differences between electrocardiogram signs of left bundle-branch block and left-ventricular uncoupling
    Mark Potse
    Institute of Computational Science, Faculty of Informatics, Università della Svizzera italiana, Via Giuseppe Buffi 13, Lugano, Switzerland
    Europace 14:v33-v39. 2012
    ..We used a realistic large-scale computer model to evaluate the effects of uncoupling with and without left-sided block and in combination with biventricular pacing...
  4. pmc Mathematical modeling and simulation of ventricular activation sequences: implications for cardiac resynchronization therapy
    Mark Potse
    Institute of Computational Science, University of Lugano, Via Giuseppe Buffi 13, 6904 Lugano, Switzerland
    J Cardiovasc Transl Res 5:146-58. 2012
    ....
  5. pmc Cardiac anisotropy in boundary-element models for the electrocardiogram
    Mark Potse
    Research Center, Sacre Coeur Hospital, 5400 Boulevard Gouin Ouest, Montreal, QC, H4J 1C5, Canada
    Med Biol Eng Comput 47:719-29. 2009
    ..A model that accounted only for intracellular anisotropy showed intermediate performance. We conclude that using a compound anisotropy ratio allows BEM-based ECG models to more accurately represent both anisotropies...
  6. doi Validation of a simple model for the morphology of the T wave in unipolar electrograms
    Mark Potse
    Institute of Biomedical Engineering, Universite de Montreal, Montreal, Quebec, Canada
    Am J Physiol Heart Circ Physiol 297:H792-801. 2009
    ....
  7. ncbi The role of extracellular potassium transport in computer models of the ischemic zone
    Mark Potse
    Research Center, Sacre Coeur Hospital, 5400 Boulevard Gouin Ouest, Montreal, QC, Canada, H4J 1C5
    Med Biol Eng Comput 45:1187-99. 2007
    ..We discuss the role of potassium transport next to other aspects of ischemia: the mechanism of changes in action potential and ECG, cellular coupling, anisotropic bidomain tissue conductivity, and the geometry of the ischemic zone...
  8. ncbi ST elevation or depression in subendocardial ischemia?
    Mark Potse
    Res Center, Hosp du Sacre Coeur de Montreal, Que
    Conf Proc IEEE Eng Med Biol Soc 1:3899-902. 2006
    ..We hypothesize that ST depression in leads overlying an ischemic zone is due to subendocardial ischemia in tissue where a redistribution of gap junctions has taken place...
  9. ncbi A comparison of monodomain and bidomain propagation models for the human heart
    Mark Potse
    Res Center, Hosp du Sacre Coeur de Montreal, Que
    Conf Proc IEEE Eng Med Biol Soc 1:3895-8. 2006
    ..We conclude that, in the absence of applied currents, propagating action potentials on the scale of a human heart can be studied with a monodomain model...
  10. ncbi The positive T wave
    Mark Potse
    Department of Physiology, Institute of Biomedical Engineering, Universite de Montreal, Montreal, Quebec, Canada
    Anadolu Kardiyol Derg 7:164-7. 2007
    ..The purpose of this study was to elucidate the mechanism that leads to positive and negative T waves and to investigate which electrogram feature best predicts TR...
  11. ncbi Understanding ST depression in the stress-test ECG
    Mark Potse
    Research Center, Hôpital du Sacré Coeur, Montreal, Quebec, Canada
    Anadolu Kardiyol Derg 7:145-7. 2007
    ..An alternative explanation for ST depression specific to stress testing involves global subendocardial ischemia. In this study, we evaluated both explanations with a realistic mathematical model of the human heart...
  12. ncbi Why do we need supercomputers to understand the electrocardiographic T wave?
    Mark Potse
    Research Center, Hôpital du Sacré Coeur, Department of Physiology, Institute of Biomedical Engineering, Universite de Montreal, Quebec, Canada
    Anadolu Kardiyol Derg 7:123-4. 2007
    ..Solving RD equations for a whole heart requires a supercomputer. Therefore, earlier models used predefined action potential (AP) shapes and fixed propagation velocities. We discuss why RD models are important when T waves are studied...
  13. ncbi Properties of unipolar electrograms recorded with a multielectrode basket catheter
    Mark Potse
    Department of Medical Physics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Electrocardiol 37:1-10. 2004
    ..In conclusion, unipolar mapping using a basket catheter can be used with confidence for the creation of activation maps if appropriate care is taken in the interpretation of fractionated electrograms...
  14. ncbi A comparison of monodomain and bidomain reaction-diffusion models for action potential propagation in the human heart
    Mark Potse
    Department of Physiology, Institute of Biomedical Engineering, Universite de Montreal, P O Box 6128, Station Centre Ville, Montreal, QC H3C 3J7, Canada
    IEEE Trans Biomed Eng 53:2425-35. 2006
    ..We conclude that, in the absence of applied currents, propagating action potentials on the scale of a human heart can be studied with a monodomain model...
  15. ncbi Simulation of QRST integral maps with a membrane-based computer heart model employing parallel processing
    Marie Claude Trudel
    Institute of Biomedical Engineering, Universite de Montreal, Montreal, Canada
    IEEE Trans Biomed Eng 51:1319-29. 2004
    ..Finally, the sensitivity of QRST integral maps to local alterations in action-potential duration was investigated...
  16. ncbi The effect of lesion size and tissue remodeling on ST deviation in partial-thickness ischemia
    Mark Potse
    Research Center, Sacre Coeur Hospital, Montreal, Quebec, Canada mark potse nl
    Heart Rhythm 4:200-6. 2007
    ..ST depression in epicardium overlying the ischemic zone indicates that the ischemia is nontransmural. However, nontransmural ischemia does not always cause ST depression. Especially in animal models, ST depression is hard to reproduce...
  17. ncbi Modeling transport of interstitial potassium in regional myocardial ischemia: effect on the injury current
    Mark Potse
    Research Center, Hopital du Sacre Coeur de Montreal, 5400 Boulevard Gouin Ouest, Montréal Québec H4J 1C5, Canada
    Conf Proc IEEE Eng Med Biol Soc 2007:6331-4. 2007
    ..This suggests that activation is more likely to occur at the endocardium, where the potassium gradient is steeper...
  18. doi ST segment elevation by current-to-load mismatch: an experimental and computational study
    Mark G Hoogendijk
    Department of Experimental Cardiology, Heart Failure Research Center, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Heart Rhythm 8:111-8. 2011
    ..In patients with Brugada syndrome, ST segment elevation is modulated by cardiac sodium (I(Na)), transient outward (I(to)), and L-type calcium currents (I(CaL))...
  19. doi A computer model of endo-epicardial electrical dissociation and transmural conduction during atrial fibrillation
    Ali Gharaviri
    Department of Physiology, Maastricht University, Maastricht, The Netherlands
    Europace 14:v10-v16. 2012
    ..The aim of the study was to investigate the role of transmural conduction in the stability of AF episodes using a dual-layer computer model...
  20. doi [Multiscale modeling of cardiac electrical activity]
    Philippe Comtois
    Institut de Cardiologie de Montreal, Institut de Génie Biomédical, Universite de Montreal, Montreal, Canada
    Med Sci (Paris) 26:57-64. 2010
    ..In each case, the methods, results and limitations are discussed...
  21. ncbi Dynamics of sustained reentry in a loop model with discrete gap junction resistances
    Wei Chen
    Department of Physiology, Institute of Biomedical Engineering, Universite de Montreal, Montreal, Canada H4J 1C5
    Phys Rev E Stat Nonlin Soft Matter Phys 76:021928. 2007
    ..An increase of R does not seem to increase the number of possible QP solutions since, as in the continuous cable, only two QP modes of propagation were found despite an extensive search through alternative initial conditions...
  22. ncbi Simulating T-wave parameters of local extracellular electrograms with a whole-heart bidomain reaction-diffusion model: Size matters!
    Mark Potse
    Research Center, Hopital du Sacre Coeur de Montreal, Montréal Québec H4J 1C5, Canada
    Conf Proc IEEE Eng Med Biol Soc 2007:6644-7. 2007
    ..By sacrificing some spatial resolutions, we kept the computational requirements within acceptable limits for multiple simulations...
  23. doi Mechanoelectrical coupling enhances initiation and affects perpetuation of atrial fibrillation during acute atrial dilation
    Nico H L Kuijpers
    Department of Biomedical Engineering, Maastricht University, Maastricht, The Netherlands
    Heart Rhythm 8:429-36. 2011
    ..Acute atrial dilation increases the susceptibility to atrial fibrillation (AF). However, the mechanisms by which atrial stretch may contribute to the initiation and perpetuation of AF remain to be determined...
  24. ncbi How disruption of endo-epicardial electrical connections enhances endo-epicardial conduction during atrial fibrillation
    Ali Gharaviri
    Department of Physiology and Maastricht Centre of Systems Biology, Maastricht University, PO Box 616, Maastricht 6200 MD, The Netherlands
    Europace . 2016
    ..We tested the hypothesis that endo-epicardial uncoupling enhances endo-epicardial electrical dyssynchrony, breakthrough rate (BTR), and AF stability...
  25. doi An in-silico analysis of the effect of heart position and orientation on the ECG morphology and vectorcardiogram parameters in patients with heart failure and intraventricular conduction defects
    Uyên Châu Nguyên
    Faculty of Medicine, Maastricht University, Maastricht, The Netherlands
    J Electrocardiol 48:617-25. 2015
    ..The aim of this study was to investigate the influence of geometrical factors on the ECG morphology and vectorcardiogram (VCG) parameters...
  26. doi In vivo electromechanical assessment of heart failure patients with prolonged QRS duration
    Wilco Kroon
    Center for Computational Medicine in Cardiology, Institute of Computational Science, University of Lugano, Lugano, Switzerland
    Heart Rhythm 12:1259-67. 2015
    ..Combined measurement of electrical activation and mechanical dyssynchrony in heart failure (HF) patients is scarce but may contain important mechanistic and diagnostic clues...
  27. doi Mechanism of right precordial ST-segment elevation in structural heart disease: excitation failure by current-to-load mismatch
    Mark G Hoogendijk
    Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Heart Rhythm 7:238-48. 2010
    ..The Brugada sign has been associated with mutations in SCN5A and with right ventricular structural abnormalities. Their role in the Brugada sign and the associated ventricular arrhythmias is unknown...
  28. ncbi Software design for analysis of multichannel intracardial and body surface electrocardiograms
    Mark Potse
    Medical Physics Department, Academic Medical Center AMC, University of Amsterdam, PO Box 22700, 1100 DE, Amsterdam, The Netherlands
    Comput Methods Programs Biomed 69:225-36. 2002
    ..The source code is made intelligible using software for structured documentation and is available to the users. The package is currently used by more than ten research groups analysing ECG data worldwide...
  29. doi Segmentation of the left ventricular endocardium from magnetic resonance images by using different statistical shape models
    Concetta Piazzese
    Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Italy Centre for Computational Medicine in Cardiology, Institute of Computational Science, Università della Svizzera italiana, Lugano, Switzerland Electronic address
    J Electrocardiol 49:383-91. 2016
    ..A high correlation (r(2)>0.92) was found in all cases, with better results when using the SSM models comprising more than one frame of the cardiac cycle. ..
  30. ncbi Electrical conduction in canine pulmonary veins: electrophysiological and anatomic correlation
    Meleze Hocini
    Hopital Cardiologique du Haut Leveque, Pessac, France
    Circulation 105:2442-8. 2002
    ..The mechanism of these initiating arrhythmias is unknown. The aim of this study was to determine electrophysiological characteristics of canine pulmonary veins that may predispose to initiating arrhythmias...