M Vaneker

Summary

Affiliation: Radboud University Nijmegen Medical Centre
Country: The Netherlands

Publications

  1. ncbi request reprint Mechanical ventilation in healthy mice induces reversible pulmonary and systemic cytokine elevation with preserved alveolar integrity: an in vivo model using clinical relevant ventilation settings
    Michiel Vaneker
    Department of Anesthesiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Anesthesiology 107:419-26. 2007
  2. doi request reprint Low-tidal-volume mechanical ventilation induces a toll-like receptor 4-dependent inflammatory response in healthy mice
    Michiel Vaneker
    Department of Anesthesiology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Anesthesiology 109:465-72. 2008
  3. doi request reprint Isoflurane attenuates pulmonary interleukin-1beta and systemic tumor necrosis factor-alpha following mechanical ventilation in healthy mice
    M Vaneker
    Departments of Anesthesiology and Intensive Care, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Acta Anaesthesiol Scand 53:742-8. 2009
  4. doi request reprint Mechanical ventilation induces a Toll/interleukin-1 receptor domain-containing adapter-inducing interferon beta-dependent inflammatory response in healthy mice
    Michiel Vaneker
    Department of Anesthesiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Anesthesiology 111:836-43. 2009
  5. doi request reprint Resveratrol attenuates NF-κB-binding activity but not cytokine production in mechanically ventilated mice
    S E I VAN DER Wal
    Department of Anesthesiology, Radboud University Nijmegen Medical Centre RUNMC, Nijmegen, The Netherlands
    Acta Anaesthesiol Scand 58:487-94. 2014
  6. doi request reprint α7 nicotinic acetylcholine receptor agonist GTS-21 attenuates ventilator-induced tumour necrosis factor-α production and lung injury
    M Kox
    Department of Intensive Care Medicine, Radboud University Nijmegen Medical Centre, Geert Grooteplein 10, 6500 HB Nijmegen, The Netherlands
    Br J Anaesth 107:559-66. 2011
  7. ncbi request reprint Cytokines and biotrauma in ventilator-induced lung injury: a critical review of the literature
    F J J Halbertsma
    Department of Paediatric Intensive Care, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Neth J Med 63:382-92. 2005
  8. doi request reprint The in vitro mechanisms and in vivo efficacy of intravenous lidocaine on the neuroinflammatory response in acute and chronic pain
    S E I VAN DER Wal
    Department of Anesthesiology, Pain and Palliative Medicine, Radboud University Medical Center RUMC, Nijmegen, The Netherlands
    Eur J Pain 20:655-74. 2016
  9. doi request reprint Lidocaine increases the anti-inflammatory cytokine IL-10 following mechanical ventilation in healthy mice
    S van der Wal
    Department of Anesthesiology, Pain and Palliative Care, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Acta Anaesthesiol Scand 59:47-55. 2015
  10. doi request reprint Hypercapnic acidosis attenuates the pulmonary innate immune response in ventilated healthy mice
    Feico J J Halbertsma
    Maxima Medical Centre, Veldhoven, The Netherlands
    Crit Care Med 36:2403-6. 2008

Collaborators

  • M Kox
  • Feico J Halbertsma
  • M G Netea
  • P Pickkers
  • D G Snijdelaar
  • S E I VAN DER Wal
  • G J Scheffer
  • S van der Wal
  • K C P Vissers
  • S A Radema
  • S A S van den Heuvel
  • M A H Steegers
  • B F M van Berkum
  • J van der Laak
  • B VAN Berkum
  • M Steegers
  • J van der Hoeven
  • K Vissers
  • L A B Joosten
  • L M Heunks
  • H W H van Hees
  • I A VAN DEN Brink
  • J G van der Hoeven
  • G Braak
  • F M VAN DE Pol

Detail Information

Publications11

  1. ncbi request reprint Mechanical ventilation in healthy mice induces reversible pulmonary and systemic cytokine elevation with preserved alveolar integrity: an in vivo model using clinical relevant ventilation settings
    Michiel Vaneker
    Department of Anesthesiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Anesthesiology 107:419-26. 2007
    ..To study mechanotransduction in vivo, the authors used an animal MV model with clinically relevant ventilator settings, avoiding alveolar damage...
  2. doi request reprint Low-tidal-volume mechanical ventilation induces a toll-like receptor 4-dependent inflammatory response in healthy mice
    Michiel Vaneker
    Department of Anesthesiology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Anesthesiology 109:465-72. 2008
    ..A role for proinflammatory pathways has been proposed. The current studies analyzed the roles of Toll-like receptor (TLR) 4 and TLR2 involvement in the inflammatory response after MV in the healthy lung...
  3. doi request reprint Isoflurane attenuates pulmonary interleukin-1beta and systemic tumor necrosis factor-alpha following mechanical ventilation in healthy mice
    M Vaneker
    Departments of Anesthesiology and Intensive Care, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Acta Anaesthesiol Scand 53:742-8. 2009
    ..Isoflurane is known to have protective immunological effects on different organ systems. We tested the hypothesis that the MV-induced inflammatory response in healthy lungs is reduced by isoflurane...
  4. doi request reprint Mechanical ventilation induces a Toll/interleukin-1 receptor domain-containing adapter-inducing interferon beta-dependent inflammatory response in healthy mice
    Michiel Vaneker
    Department of Anesthesiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Anesthesiology 111:836-43. 2009
    ....
  5. doi request reprint Resveratrol attenuates NF-κB-binding activity but not cytokine production in mechanically ventilated mice
    S E I VAN DER Wal
    Department of Anesthesiology, Radboud University Nijmegen Medical Centre RUNMC, Nijmegen, The Netherlands
    Acta Anaesthesiol Scand 58:487-94. 2014
    ..Resveratrol (RVT) exhibits anti-inflammatory effects in vitro and in vivo supposedly by interfering with TLR4 signaling and NF-κB. In the present study, we investigated the role of RVT in MV-induced inflammation in mice...
  6. doi request reprint α7 nicotinic acetylcholine receptor agonist GTS-21 attenuates ventilator-induced tumour necrosis factor-α production and lung injury
    M Kox
    Department of Intensive Care Medicine, Radboud University Nijmegen Medical Centre, Geert Grooteplein 10, 6500 HB Nijmegen, The Netherlands
    Br J Anaesth 107:559-66. 2011
    ....
  7. ncbi request reprint Cytokines and biotrauma in ventilator-induced lung injury: a critical review of the literature
    F J J Halbertsma
    Department of Paediatric Intensive Care, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Neth J Med 63:382-92. 2005
    ..Mechanical ventilation is known to induce and aggravate lung injury. One of the underlying mechanisms is biotrauma, an inflammatory response in which cytokines play a crucial role...
  8. doi request reprint The in vitro mechanisms and in vivo efficacy of intravenous lidocaine on the neuroinflammatory response in acute and chronic pain
    S E I VAN DER Wal
    Department of Anesthesiology, Pain and Palliative Medicine, Radboud University Medical Center RUMC, Nijmegen, The Netherlands
    Eur J Pain 20:655-74. 2016
    ..This review delineates the current literature concerning in vitro mechanisms and in vivo efficacy of iv lidocaine on the neuroinflammatory response in acute and chronic pain...
  9. doi request reprint Lidocaine increases the anti-inflammatory cytokine IL-10 following mechanical ventilation in healthy mice
    S van der Wal
    Department of Anesthesiology, Pain and Palliative Care, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Acta Anaesthesiol Scand 59:47-55. 2015
    ..We hypothesized an attenuation of MV-induced inflammatory response with intravenously administered lidocaine...
  10. doi request reprint Hypercapnic acidosis attenuates the pulmonary innate immune response in ventilated healthy mice
    Feico J J Halbertsma
    Maxima Medical Centre, Veldhoven, The Netherlands
    Crit Care Med 36:2403-6. 2008
    ....