Lambertus A Kiemeney

Summary

Affiliation: Radboud University Nijmegen Medical Centre
Country: The Netherlands

Publications

  1. ncbi request reprint No evidence for large-scale germline genomic aberrations in hereditary bladder cancer patients with high-resolution array-based comparative genomic hybridization
    Lambertus A Kiemeney
    Department of Urology, Radboud University Nijmegen Medical Centre, P O Box 9101, NL 6500 HB Nijmegen, The Netherlands
    Cancer Epidemiol Biomarkers Prev 15:180-3. 2006
  2. doi request reprint Hereditary bladder cancer
    Lambertus A L M Kiemeney
    Department of Epidemiology and Biostatistics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Scand J Urol Nephrol Suppl . 2008
  3. pmc Detection of rotator cuff tears: the value of MRI following ultrasound
    Matthieu J C M Rutten
    Department of Radiology, Jeroen Bosch Ziekenhuis, Nieuwstraat 34, 5211, NL s Hertogenbosch, The Netherlands
    Eur Radiol 20:450-7. 2010
  4. ncbi request reprint Site-specific familial aggregation of prostate cancer
    Bas A J Verhage
    Center for Prevention and Health Services Research PZO, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    Int J Cancer 109:611-7. 2004
  5. ncbi request reprint Screening for prostate cancer in Dutch hereditary prostate cancer families
    Lambertus A Kiemeney
    Department of Epidemiology and Biostatistics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Int J Cancer 122:871-6. 2008
  6. ncbi request reprint Accurate prediction of need for invasive treatment in alpha1-blocker treated patients with benign prostatic hyperplasia not possible: bootstrap validation analysis
    Lambertus A L M Kiemeney
    Department of Urology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Urology 67:984-9. 2006
  7. ncbi request reprint Gene expression analysis for the prediction of recurrence in patients with primary Ta urothelial cell carcinoma
    Iman J Schultz
    Department of Clinical Chemistry, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Eur Urol 51:416-22; discussion 422-3. 2007
  8. doi request reprint Periprostatic fat correlates with tumour aggressiveness in prostate cancer patients
    Joep G H van Roermund
    Department of Urology, University Medical Center Utrecht, Utrecht, The Netherlands
    BJU Int 107:1775-9. 2011
  9. doi request reprint Polymorphisms in the H19 gene and the risk of bladder cancer
    Gerald W Verhaegh
    Department of Urology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Eur Urol 54:1118-26. 2008
  10. pmc A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer
    Lambertus A Kiemeney
    Department of Epidemiology, Biostatistics and Health Technology Assessment, Nijmegen, The Netherlands
    Nat Genet 42:415-9. 2010

Detail Information

Publications86

  1. ncbi request reprint No evidence for large-scale germline genomic aberrations in hereditary bladder cancer patients with high-resolution array-based comparative genomic hybridization
    Lambertus A Kiemeney
    Department of Urology, Radboud University Nijmegen Medical Centre, P O Box 9101, NL 6500 HB Nijmegen, The Netherlands
    Cancer Epidemiol Biomarkers Prev 15:180-3. 2006
  2. doi request reprint Hereditary bladder cancer
    Lambertus A L M Kiemeney
    Department of Epidemiology and Biostatistics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Scand J Urol Nephrol Suppl . 2008
    ..Genome-wide association studies are better suited to identify these genes. Three such studies are currently underway and are expected to report their results in 2008...
  3. pmc Detection of rotator cuff tears: the value of MRI following ultrasound
    Matthieu J C M Rutten
    Department of Radiology, Jeroen Bosch Ziekenhuis, Nieuwstraat 34, 5211, NL s Hertogenbosch, The Netherlands
    Eur Radiol 20:450-7. 2010
    ....
  4. ncbi request reprint Site-specific familial aggregation of prostate cancer
    Bas A J Verhage
    Center for Prevention and Health Services Research PZO, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    Int J Cancer 109:611-7. 2004
    ..5; 95% CI = 1.7-3.6). Cancers at other sites did not coaggregate with PC. Our data suggest that familial PC, at least in this Western European population, is site-specific, not part of an inherited cancer syndrome...
  5. ncbi request reprint Screening for prostate cancer in Dutch hereditary prostate cancer families
    Lambertus A Kiemeney
    Department of Epidemiology and Biostatistics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Int J Cancer 122:871-6. 2008
    ..We suggest that the same PSA testing guidelines should apply to HPC families and the general population. A more aggressive screening policy in HPC families does not seem to be justified...
  6. ncbi request reprint Accurate prediction of need for invasive treatment in alpha1-blocker treated patients with benign prostatic hyperplasia not possible: bootstrap validation analysis
    Lambertus A L M Kiemeney
    Department of Urology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Urology 67:984-9. 2006
    ..However, the clinical relevance of such factors is rarely quantified. We evaluated the accuracy of predicting the need for invasive treatment among patients with benign prostatic hyperplasia treated conservatively with alpha1-blockers...
  7. ncbi request reprint Gene expression analysis for the prediction of recurrence in patients with primary Ta urothelial cell carcinoma
    Iman J Schultz
    Department of Clinical Chemistry, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Eur Urol 51:416-22; discussion 422-3. 2007
    ..This study aims at discriminating between patients with primary Ta UCC and long or short recurrence-free periods...
  8. doi request reprint Periprostatic fat correlates with tumour aggressiveness in prostate cancer patients
    Joep G H van Roermund
    Department of Urology, University Medical Center Utrecht, Utrecht, The Netherlands
    BJU Int 107:1775-9. 2011
    ..Prognostic (case series)...
  9. doi request reprint Polymorphisms in the H19 gene and the risk of bladder cancer
    Gerald W Verhaegh
    Department of Urology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Eur Urol 54:1118-26. 2008
    ..In this study we examined whether sequence variants within the H19 gene are associated with the risk of developing bladder cancer...
  10. pmc A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer
    Lambertus A Kiemeney
    Department of Epidemiology, Biostatistics and Health Technology Assessment, Nijmegen, The Netherlands
    Nat Genet 42:415-9. 2010
    ..The frequency of rs798766[T] is higher in Ta tumors that carry an activating mutation in FGFR3 than in Ta tumors with wild-type FGFR3. Our results show a link between germline variants, somatic mutations of FGFR3 and risk of UBC...
  11. ncbi request reprint The prognostic role of the STK15 T91A polymorphism and of STK15 mRNA expression in patients with urothelial cell carcinoma
    Iman J Schultz
    Department of Clinical Chemistry, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Anticancer Res 27:1025-30. 2007
    ..The prognostic role of the STK15 T91A polymorphism and of STK15 mRNA expression was investigated in patients with urothelial cell carcinoma (UCC)...
  12. doi request reprint Is there a relationship between fatigue perception and the serum levels of thyrotropin and free thyroxine in euthyroid subjects?
    Annenienke C van de Ven
    Department of Endocrinology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Thyroid 22:1236-43. 2012
    ..Thyrotoxicosis and hypothyroidism are associated with fatigue. Here we studied euthyroid subjects to determine if there was a relationship between serum thyrotropin (TSH), free thyroxine (FT(4)) and thyroperoxidase antibodies and fatigue...
  13. doi request reprint Fruit and vegetable consumption and risk of aggressive and non-aggressive urothelial cell carcinomas in the European Prospective Investigation into Cancer and Nutrition
    Martine M Ros
    Centre for Nutrition and Health, National Institute for Public Health and the Environment RIVM, Bilthoven, The Netherlands
    Eur J Cancer 48:3267-77. 2012
    ..Therefore, we examined the relation between fruit and vegetable consumption and the risk of aggressive and non-aggressive UCC in the European Prospective Investigation into Cancer and Nutrition (EPIC)...
  14. doi request reprint Impact of obesity on surgical outcomes following open radical prostatectomy
    Joep G H van Roermund
    Department of Urology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Urol Int 82:256-61. 2009
    ..It is unknown whether obesity affects the surgical and oncological outcomes following open radical retropubic prostatectomy (RRP). Knowledge concerning this issue is relevant when counselling obese patients with PCa for RRP...
  15. doi request reprint A single institution experience with biochemical recurrence after radical prostatectomy for tumors that on pathology are of small volume or "insignificant"
    I M van Oort
    Department of Urology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Urol Oncol 27:509-13. 2009
    ..5 cc and Gleason scores <7, InsigPC) are considered clinically insignificant by some investigators. The aim of this study is to determine the biochemical recurrence rate (BCR) of svPC and InsigPC in prostatectomy specimens...
  16. ncbi request reprint DD3(PCA3)-based molecular urine analysis for the diagnosis of prostate cancer
    Daphne Hessels
    Department of Experimental Urology, Nijmegen Center for Molecular Life Sciences, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Eur Urol 44:8-15; discussion 15-6. 2003
    ..DD3(PCA3) is the most prostate cancer-specific gene described to date. To assess the clinical utility of DD3(PCA3) a time-resolved fluorescence-based, quantitative RT-PCR analysis for DD3(PCA3) was developed...
  17. doi request reprint Body mass index is not a prognostic marker for prostate-specific antigen failure and survival in Dutch men treated with brachytherapy
    Joep G H van Roermund
    Department of Urology, University Medical Center Utrecht, University Medical Center Utrecht, Utrecht, The Netherlands
    BJU Int 105:42-8. 2010
    ....
  18. doi request reprint Clinical epidemiology of nonurothelial bladder cancer: analysis of the Netherlands Cancer Registry
    Martine Ploeg
    Department of Urology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Urol 183:915-20. 2010
    ..Nonurothelial malignancies represent a small fraction of bladder malignancies and are less extensively studied, resulting in sparse empirical data on these tumors. We sought insight into tumor characteristics and survival...
  19. ncbi request reprint Prediction of recurrence in Ta urothelial cell carcinoma by real-time quantitative PCR analysis: a microarray validation study
    Iman J Schultz
    Department of Clinical Chemistry, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Int J Cancer 119:1915-9. 2006
    ..In conclusion, we were not able to confirm the microarray gene expression pattern of the 26 genes shown by Dyrskjøt et al. The discovery of accurate recurrence predictive markers, therefore, remains a challenge...
  20. pmc Periprostatic fat measured on computed tomography as a marker for prostate cancer aggressiveness
    Joep G H van Roermund
    Department of Urology, University Medical Center Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands
    World J Urol 28:699-704. 2010
    ....
  21. pmc Independent Replication of Published Germline Polymorphisms Associated with Urinary Bladder Cancer Prognosis and Treatment Response
    Anne J Grotenhuis
    Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands
    Bladder Cancer 2:77-89. 2016
    ..Most published SNP associations have never been replicated in independent patient series...
  22. doi request reprint Self-reported acne is not associated with prostate cancer
    Ruben G Cremers
    Department for Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands
    Urol Oncol 32:941-5. 2014
    ..This study aimed to evaluate the association between self-reported acne and PCa in a large case-referent study...
  23. ncbi request reprint Polymorphisms in the E-cadherin (CDH1) gene promoter and the risk of bladder cancer
    Lambertus A Kiemeney
    Department of Urology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands Department of Epidemiology and Biostatistics, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB, Nijmegen, The Netherlands
    Eur J Cancer 42:3219-27. 2006
    ..We studied the association between both polymorphisms and the risk of bladder cancer...
  24. ncbi request reprint CDC91L1 (PIG-U) mRNA expression in urothelial cell carcinomas
    Iman J Schultz
    Department of Clinical Chemistry, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Int J Cancer 116:282-4. 2005
    ..Our results suggest, in contrast to those of Guo et al. (Nat Med 2004;10:374-81), that the oncogene CDC91L1 is not overexpressed at the mRNA level in urothelial cell carcinomas and cannot be used to predict the course of the disease...
  25. pmc The clinical phenotype of hereditary versus sporadic prostate cancer: HPC definition revisited
    Ruben G Cremers
    Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands
    Prostate 76:897-904. 2016
    ..Intuitively, HPC is a serious subtype of prostate cancer but there are only limited data on the clinical phenotype of HPC. Here, we aimed to compare the prognosis of HPC to the sporadic form of prostate cancer (SPC)...
  26. doi request reprint Known susceptibility SNPs for sporadic prostate cancer show a similar association with "hereditary" prostate cancer
    Ruben G Cremers
    Department for Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands Department of Urology, Radboud University Medical Center, Nijmegen, The Netherlands The Netherlands Foundation for the Detection of Hereditary Tumours, Leiden, The Netherlands
    Prostate 75:474-83. 2015
    ..Previous studies have suggested similar associations between a selection of these SNPs and hereditary PC (HPC). Our aim was to evaluate the effect of all known PC risk SNPs and their discriminative value for SPC and HPC...
  27. pmc Prognostic relevance of urinary bladder cancer susceptibility loci
    Anne J Grotenhuis
    Department for Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands
    PLoS ONE 9:e89164. 2014
    ..Elucidation of the causal variant(s) could further our understanding of the mechanism of disease, could point to new therapeutic targets, and might aid in improvement of prognostic tools...
  28. ncbi request reprint Allelic imbalance in hereditary and sporadic prostate cancer
    Bas A J Verhage
    Department of Urology, University Medical Center Nijmegen, The Netherlands
    Prostate 54:50-7. 2003
    ....
  29. ncbi request reprint Plasma carotenoids and vitamin C concentrations and risk of urothelial cell carcinoma in the European Prospective Investigation into Cancer and Nutrition
    Martine M Ros
    National Institute for Public Health and the Environment, Bilthoven, Netherlands
    Am J Clin Nutr 96:902-10. 2012
    ..Published associations between dietary carotenoids and vitamin C and bladder cancer risk are inconsistent. Biomarkers may provide more accurate measures of nutrient status...
  30. doi request reprint Androgenic alopecia is not useful as an indicator of men at high risk of prostate cancer
    Ruben G Cremers
    Department of Epidemiology, Biostatistics and HTA, Radboud University Nijmegen Medical Centre, The Netherlands
    Eur J Cancer 46:3294-9. 2010
    ..A correlation between the two phenotypes may be relevant for identification of men at high risk of PC. We evaluated the association between AA at different ages and PC in a large case-control study...
  31. ncbi request reprint Spouse controls in family case-control studies: a methodological consideration
    Bas A J Verhage
    Department of Epidemiology and Biostatistics, University Medical Centre Nijmegen, Nijmegen, The Netherlands
    Fam Cancer 2:101-8. 2003
    ..Using a simulation study it is illustrated that even strong assortative mating on a factor, which is strongly correlated with a true risk factor under study, will have a negligible effect on the observed extent of familial aggregation...
  32. doi request reprint The role of the prostate cancer gene 3 urine test in addition to serum prostate-specific antigen level in prostate cancer screening among breast cancer, early-onset gene mutation carriers
    Ruben G Cremers
    Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands
    Urol Oncol 33:202.e19-28. 2015
    ..This study was performed among the Dutch participants of IMPACT, a large international study on the effectiveness of PSA screening among BRCA mutation carriers...
  33. doi request reprint The effect of smoking and timing of smoking cessation on clinical outcome in non-muscle-invasive bladder cancer
    Anne J Grotenhuis
    Department for Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands
    Urol Oncol 33:65.e9-17. 2015
    ..We evaluated the effect of smoking status and intensity, and timing of smoking cessation, on NMIBC prognosis...
  34. ncbi request reprint Survivin mRNA copy number in bladder washings predicts tumor recurrence in patients with superficial urothelial cell carcinomas
    Iman J Schultz
    Department of Clinical Chemistry, University Medical Center Nijmegen, Nijmegen, The Netherlands
    Clin Chem 50:1425-8. 2004
  35. doi request reprint Body mass index as a prognostic marker for biochemical recurrence in Dutch men treated with radical prostatectomy
    Joep G H van Roermund
    Department of Urology, University Medical Center Utrecht, The Netherlands
    BJU Int 104:321-5. 2009
    ....
  36. ncbi request reprint Single-nucleotide polymorphism in the E-cadherin gene promoter modifies the risk of prostate cancer
    Bas A J Verhage
    Department of Urology 252 EPIB, University Medical Centre Nijmegen, NL 6500 HB Nijmegen, The Netherlands
    Int J Cancer 100:683-5. 2002
    ..6, 95% CI 2.0-6.4) compared to C-only carriers. AC and AA genotypes had an increased risk of PCa (OR = 3.8, 95% CI 2.1-6.8 and OR = 1.7, 95% CI 0.4-6.6, respectively) compared to CC genotypes...
  37. pmc Personal hair dye use and the risk of bladder cancer: a case-control study from The Netherlands
    Martine M Ros
    Department of Epidemiology, Biostatistics and HTA, Radboud University Medical Centre, Nijmegen, The Netherlands
    Cancer Causes Control 23:1139-48. 2012
    ..There has also been concern about a possible increased risk of bladder cancer among users of hair dyes. However, the association between personal hair dye use and bladder cancer risk remains inconclusive...
  38. doi request reprint Prognostic factors for survival in patients with recurrence of muscle invasive bladder cancer after treatment with curative intent
    Martine Ploeg
    Department of Urology, Radboud University Nijmegen Medical Centre, The Netherlands
    Clin Genitourin Cancer 9:14-21. 2011
    ..Multivariable survival analyses were performed. Clinicopathological factors that predict survival after recurrence are recurrence location, treatment for recurrence and age at recurrence diagnosis...
  39. pmc Sequence variant on 8q24 confers susceptibility to urinary bladder cancer
    Lambertus A Kiemeney
    Department of Epidemiology and Biostatistics, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands
    Nat Genet 40:1307-12. 2008
    ..A weaker signal, but nonetheless of genome-wide significance, was captured by rs710521[A] located near TP63 on chromosome 3q28 (allele-specific OR = 1.19; P = 1. 15 x 10(-7))...
  40. doi request reprint Genome-wide association studies in bladder cancer: first results and potential relevance
    Lambertus A Kiemeney
    Department of Epidemiology, Biostatistics and HTA, The Netherlands
    Curr Opin Urol 19:540-6. 2009
    ..All GWASs have been published in high-impact journals and the strengths of the design are acknowledged by all experts, but there is criticism about the relevance of the results. Late 2008, the first GWAS in bladder cancer was published...
  41. ncbi request reprint Phenotypic characteristics of male subfertility and its familial occurrence
    Ron J T van Golde
    Department of Obstetrics and Gynecology, University Medical Centre Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    J Androl 25:819-23. 2004
    ..Furthermore, examination of the data suggests that subfertile men with a familial occurrence of male subfertility more often have normal levels of FSH and LH and a lower percentage of motile sperm...
  42. pmc The prognostic value of family history among patients with urinary bladder cancer
    Lieke Egbers
    Department for Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands
    Int J Cancer 136:1117-24. 2015
    ..This study shows that a first-degree family history of UBC is not clearly associated with NMIBC prognosis. Family history does not aid in prediction of NMIBC recurrence or progression. ..
  43. doi request reprint Combining risk markers improves cardiovascular risk prediction in women
    Suzanne Holewijn
    Department of General Internal Medicine, Division of Vascular Medicine, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB, Nijmegen, The Netherlands
    Clin Sci (Lond) 126:139-46. 2014
    ..The additive value of individual and combined non-invasive risk markers in men is limited to men at intermediate risk only, and to a lesser extent than in women...
  44. ncbi request reprint The efficacy of different follow-up strategies in clinical stage I Non-seminomatous Germ Cell Cancer: a Markov simulation study
    Jesse Roan Spermon
    Department of Urology, Radboud University Nijmegen Medical Center, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Eur Urol 48:258-67; discussion 267-8. 2005
    ..In this study, we constructed a Markov model to evaluate the impact of different follow-up strategies on disease-specific mortality (DSM) and life expectancy (LE) of patients with CS I NSGCT...
  45. ncbi request reprint Ultrasound-guided transrectal implantation of gold markers for prostate localization during external beam radiotherapy: complication rate and risk factors
    Johan F Langenhuijsen
    Department of Urology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Int J Radiat Oncol Biol Phys 69:671-6. 2007
    ..To report the complication rate and risk factors of transrectally implanted gold markers, used for prostate position verification and correction procedures...
  46. ncbi request reprint The prevalence of urinary incontinence in community-dwelling married women: a matter of definition
    Vera Vandoninck
    Department of Urology, University Medical Center, Nijmegen, The Netherlands
    BJU Int 94:1291-5. 2004
    ..To determine the prevalence of female urinary incontinence (UI) and its impact on quality of life...
  47. doi request reprint Germline genetic markers for urinary bladder cancer risk, prognosis and treatment response
    Anne J Grotenhuis
    Department of Epidemiology, Biostatistics and HTA, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Future Oncol 6:1433-60. 2010
    ....
  48. ncbi request reprint Underestimation of subfertility among relatives when using a family history: taboo bias
    Irene A M van der Avoort
    Department of Obstetrics and Gynaecology, University Medical Centre Nijmegen, Nijmegen, The Netherlands
    J Androl 24:285-8. 2003
    ..Therefore, researchers and clinicians should be aware that an inquiry of family history is likely to lead to underestimation of subfertility among relatives...
  49. ncbi request reprint Baseline prostatic specific antigen does not predict the outcome of high energy transurethral microwave thermotherapy
    M Pilar Laguna
    Department of Urology, University Medical Centre St Radboud, Nijmegen, The Netherlands
    J Urol 167:1727-30. 2002
    ..We assessed the prognostic value of baseline prostate specific antigen (PSA) for outcome after high energy transurethral thermotherapy in patients with lower urinary tract symptoms...
  50. doi request reprint Underestimation of effect of thyroid function parameters on morbidity and mortality due to intra-individual variation
    Annenienke C van de Ven
    Department of Endocrinology 471, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    J Clin Endocrinol Metab 96:E2014-7. 2011
    ....
  51. pmc The present and future burden of urinary bladder cancer in the world
    Martine Ploeg
    Department of Urology, Radboud University Nijmegen Medical Centre, PO Box 9101, Nijmegen 6500 HB, The Netherlands
    World J Urol 27:289-93. 2009
    ..But the burden of UBC will increase in less developed areas of the world. These changes can be attributed to global changes in exposure to risk factors for UBC and growth and aging of the world population...
  52. pmc Multicenter analysis of the SLC6A3/DAT1 VNTR haplotype in persistent ADHD suggests differential involvement of the gene in childhood and persistent ADHD
    Barbara Franke
    Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Neuropsychopharmacology 35:656-64. 2010
    ..However, the data might also imply that DAT1 has a modulatory rather than causative role in ADHD...
  53. doi request reprint The effect on pain experienced by male patients of watching their office-based flexible cystoscopy
    Erik B Cornel
    Department of Urology, Ziekenhuis Groep Twente, Hengelo, The Netherlands
    BJU Int 102:1445-6. 2008
    ..To confirm the recently published positive effect on visual analogue pain (VAS) scale levels for men watching their flexible cystoscopy...
  54. ncbi request reprint Alcohol consumption and risk of prostate cancer in middle-aged men
    W Marieke Schoonen
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Int J Cancer 113:133-40. 2005
    ..There may be, however, a reduced relative risk associated with increasing level of red wine consumption. Further research is needed to evaluate the potential negative association between red wine intake and prostate cancer risk...
  55. ncbi request reprint Familial aggregation of urothelial cell carcinoma
    Katja K H Aben
    Department of Epidemiology and Biostatistics, University Medical Centre Nijmegen, Nijmegen, The Netherlands
    Int J Cancer 98:274-8. 2002
    ..Future segregation analyses may indicate whether this clustering can be attributed to genetic susceptibility...
  56. ncbi request reprint A comparison of the diagnostic performance of systematic versus ultrasound-guided biopsies of prostate cancer
    Stijn W T P J Heijmink
    Department of Radiology, Radboud University Nijmegen Medical Centre, The Netherlands
    Eur Radiol 16:927-38. 2006
    ..Performing colour or contrast-enhanced Doppler biopsy or adding these techniques to systematic biopsies improves diagnostic performance, particularly by increasing sensitivity...
  57. ncbi request reprint Thyroid function and prevalence of anti-thyroperoxidase antibodies in a population with borderline sufficient iodine intake: influences of age and sex
    Elizabeth H Hoogendoorn
    Department of Endocrinology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Clin Chem 52:104-11. 2006
    ..We present a large European population-based study of thyroid function, performed in a population with longstanding borderline sufficient iodine intake...
  58. ncbi request reprint Hypertension, antihypertensives and mutations in the Von Hippel-Lindau gene in renal cell carcinoma: results from the Netherlands Cohort Study
    Leo J Schouten
    Department of Epidemiology, NUTRIM, Maastricht University, The Netherlands
    J Hypertens 23:1997-2004. 2005
    ..Hypertension and/or antihypertensive medication are reported to be risk factors of renal cell carcinoma (RCC). We investigated whether these risk factors are associated with von Hippel-Lindau gene (VHL) mutations in RCC...
  59. ncbi request reprint Vegetable and fruit consumption and risk of renal cell carcinoma: results from the Netherlands cohort study
    Boukje A C van Dijk
    Department of Epidemiology, NUTRIM, Maastricht University, The Netherlands
    Int J Cancer 117:648-54. 2005
    ..76; 95% CI 1.28-2.42), which must be regarded cautiously because of multiple testing. These results suggest the absence of an association between vegetable and/or fruit consumption and RCC risk...
  60. ncbi request reprint Relation of height, body mass, energy intake, and physical activity to risk of renal cell carcinoma: results from the Netherlands Cohort Study
    Boukje A C van Dijk
    Department of Epidemiology, Nutrition and Toxicology Research Institute Maastricht NUTRIM, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    Am J Epidemiol 160:1159-67. 2004
    ..These results suggest that body mass index and gain in body mass index since age 20 are associated with increased risk of RCC...
  61. ncbi request reprint Prognosis of muscle-invasive bladder cancer: difference between primary and progressive tumours and implications for therapy
    Barthold Ph Schrier
    Department of Urology 426, University Medical Centre, St Radboud, Geert Grooteplein 10, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Eur Urol 45:292-6. 2004
    ..To evaluate the difference in prognosis between progressive and primary muscle-invasive bladder cancer...
  62. ncbi request reprint Routine bladder biopsies in men with bladder outlet obstruction?
    Thomas Horn
    Department of Pathology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark
    Urology 63:451-6. 2004
    ....
  63. ncbi request reprint Inherited predisposition to prostate cancer
    Bas A J Verhage
    Centre for Prevention and Health Services Research PZO, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    Eur J Epidemiol 18:1027-36. 2003
    ..Here, we aim to review the genetic epidemiological research and the mapping efforts in the field of hereditary PCa and the consequent problems that are encountered...
  64. ncbi request reprint Segregation analysis of 389 Icelandic pedigrees with Breast and prostate cancer
    Agnes B Baffoe-Bonnie
    Department of Epidemiology, Johns Hopkins School of Hygiene and Public Health, Baltimore, Maryland 21205, USA
    Genet Epidemiol 23:349-63. 2002
    ....
  65. ncbi request reprint PSA velocity in conservatively managed BPH: can it predict the need for BPH-related invasive therapy?
    Chaidir A Mochtar
    Department of Urology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Prostate 66:1407-12. 2006
    ..To study the value of PSA velocity (PSAV) to predict benign prostatic hyperplasia (BPH) progression in patients managed with alpha(1)-blockers or watchful waiting (WW)...
  66. ncbi request reprint Risk factors for hypospadias
    Marijn M Brouwers
    Department of Epidemiology and Biostatistics 133, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB, Nijmegen, The Netherlands
    Eur J Pediatr 166:671-8. 2007
    ..The associations found in this study support the hypothesis that genetic predisposition, placental insufficiency, and substances that interfere with natural hormones play a role in the etiology of hypospadias...
  67. ncbi request reprint Polymorphisms in genes related to activation or detoxification of carcinogens might interact with smoking to increase renal cancer risk: results from The Netherlands Cohort Study on diet and cancer
    Kim M Smits
    Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
    World J Urol 26:103-10. 2008
    ..This could indicate that RCC risk among smokers might be more increased with the CYP1A1*2C genotype, GSTmicro1 null, or both a CYP1A1 variant and GSTmicro1 null...
  68. ncbi request reprint Carotenoid and vitamin intake, von Hippel-Lindau gene mutations and sporadic renal cell carcinoma
    Boukje A C van Dijk
    Department of Epidemiology, NUTRIM, Maastricht University, Maastricht, The Netherlands
    Cancer Causes Control 19:125-34. 2008
    ..We investigated whether dietary carotenoid and vitamin intake and supplemental vitamin use were inversely associated with RCC risk and with Von Hippel-Lindau (VHL)-gene mutations in clear-cell renal cell carcinoma (RCC)...
  69. doi request reprint Components of the plasminogen activator system and their complexes in renal cell and bladder cancer: comparison between normal and matched cancerous tissues
    Paul N Span
    Department of Chemical Endocrinology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    BJU Int 102:177-82. 2008
    ....
  70. ncbi request reprint Prostate cancer: body-array versus endorectal coil MR imaging at 3 T--comparison of image quality, localization, and staging performance
    Stijn W T P J Heijmink
    Department of Radiology, Radboud University Nijmegen Medical Centre, Geert Grooteplein zuid 10, NL 6500 HB, Nijmegen, The Netherlands
    Radiology 244:184-95. 2007
    ....
  71. ncbi request reprint Durability of 30-minute high-energy transurethral microwave therapy for treatment of benign prostatic hyperplasia: a study of 213 patients with and without urinary retention
    Stavros Gravas
    Department of Urology, University Hospital of Larissa, Larissa, Greece
    Urology 69:854-8. 2007
    ..To evaluate the durability of transurethral microwave therapy (TUMT) Prostasoft 3.5 for the treatment of patients with benign prostatic hyperplasia treated with the 30-minute protocol...
  72. doi request reprint The prognostic role of the pathological T2 subclassification for prostate cancer in the 2002 Tumour-Nodes-Metastasis staging system
    Inge M van Oort
    Department of Urology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    BJU Int 102:438-41. 2008
    ..To evaluate the prognostic role of the 2002 Tumour-Nodes-Metastasis (TNM) pT2 subclassification for biochemical recurrence (BCR) after radical prostatectomy (RP) for prostate cancer...
  73. ncbi request reprint Percutaneous tibial nerve stimulation in the treatment of overactive bladder: urodynamic data
    Vera Vandoninck
    Department of Urology, University Medical Center Nijmegen, The Netherlands
    Neurourol Urodyn 22:227-32. 2003
    ..The aim of this study was to evaluate urodynamic changes after percutaneous tibial nerve stimulation (PTNS) for the treatment of complaints related to overactive bladder syndrome and to search for urodynamic-based predictive factors...
  74. ncbi request reprint Fertility in men with testicular germ cell tumors
    J Roan Spermon
    Department of Urology, University Medical Center Nijmegen, The, Nijmegen, Netherlands
    Fertil Steril 79:1543-9. 2003
    ..To assess the prevalence of fertility or infertility in men before and after treatment for unilateral testicular cancer. The results were compared with the lifetime prevalence of infertility in the general population (20%-28%)...
  75. ncbi request reprint Genetic susceptibility to prostate cancer: a review
    Bas A J Verhage
    Department of Epidemiology and Urology 252 EPIB, University Medical Centre, St Radboud, Nijmegen, The Netherlands
    Fam Cancer 2:57-67. 2003
    ..Here, we aim to review the genetic epidemiological and molecular biological research in the field of hereditary prostate cancer and the problems that are encountered with this research...
  76. ncbi request reprint Long-term risk of re-treatment of patients using alpha-blockers for lower urinary tract symptoms
    Jean J M C H de la Rosette
    Department of Urology, University Medical Centre St Radboud, Nijmegen, The Netherlands
    J Urol 167:1734-9. 2002
    ..We investigated the long-term risk of re-treatment in patients using alpha-adrenoceptor blockers for lower urinary tract symptoms and the parameters that influence this risk...
  77. ncbi request reprint Human papilloma virus DNA and p53 mutation analysis on bladder washes in relation to clinical outcome of bladder cancer
    Paula M J Moonen
    Department of Urology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Eur Urol 52:464-8. 2007
    ..We aimed to study the association between presence of (high-risk) HPV DNA, p53 status, and clinical outcome in bladder cancer patients. This study must be seen as a preliminary study to investigate this potentially important problem...
  78. ncbi request reprint Posterior tibial nerve stimulation in the treatment of voiding dysfunction: urodynamic data
    Vera Vandoninck
    Department of Urology, University Medical Center Nijmegen, PO Box 9101, NL 6500 HB Nijmegen, The Netherlands
    Neurourol Urodyn 23:246-51. 2004
    ..To determine urodynamic changes and predictive factors in patients with voiding dysfunction who underwent 12 percutaneous tibial nerve stimulations...
  79. ncbi request reprint Urodynamic effects of alpha-adrenoceptor blockers: a review of clinical trials
    Barbara B M Kortmann
    Department of Urology, University Medical Center St Raboud, Nijmegen, The Netherlands
    Urology 62:1-9. 2003
  80. ncbi request reprint How strong is the association between CAG and GGN repeat length polymorphisms in the androgen receptor gene and prostate cancer risk?
    Maurice P Zeegers
    Department of Public Health and Epidemiology, School of Medicine, Public Health Building, University of Birmingham, Birmingham B15 2TT, United Kingdom
    Cancer Epidemiol Biomarkers Prev 13:1765-71. 2004
    ..The purpose of this meta-analysis was to provide relative and absolute quantitative summary estimates with sufficient power...
  81. ncbi request reprint Coal tar in dermatology
    Judith H J Roelofzen
    Department of Epidemiology and Biostatistics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Dermatolog Treat 18:329-34. 2007
    ..New, well-designed, epidemiological studies are necessary to assess the risk of skin tumors and other malignancies after dermatological use of coal tar...
  82. ncbi request reprint Treatment policy for psoriasis and eczema: a survey among dermatologists in the Netherlands and Belgian Flanders
    Judith H J Roelofzen
    Department of Epidemiology and Biostatistics, Radboud University Nijmegen Medical Centre P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Eur J Dermatol 17:416-21. 2007
    ..Despite the carcinogenicity of PUVA, this photochemotherapy is frequently prescribed by dermatologists, mainly in Flanders...
  83. ncbi request reprint Uncommon breast tumors in perspective: incidence, treatment and survival in the Netherlands
    Marieke W J Louwman
    Eindhoven Cancer Registry, Comprehensive Cancer Centre South IKZ, Eindhoven, The Netherlands
    Int J Cancer 121:127-35. 2007
    ..Communication to patients with these specific histological types should reflect this...
  84. ncbi request reprint The predictive value of p53, p27(kip1), and alpha-catenin for progression in superficial bladder carcinoma
    Barthold Ph Schrier
    Department of Urology, Radboud University Nijmegen, Medical Centre, Geert Grooteplein 10, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Eur Urol 50:76-82. 2006
    ..The aim of the study was to confirm the predictive value of cell cycle regulatory proteins, p53 and p27(kip1), and the cell adhesion complex protein alpha-catenin, for progression in patients with superficial bladder carcinoma...
  85. ncbi request reprint Polymorphisms in the alpha1A-adrenoceptor gene do not modify the short- and long-term efficacy of alpha1-adrenoceptor antagonists in the treatment of benign prostatic hyperplasia
    Chaidir A Mochtar
    Department of Urology G4 105 1, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    BJU Int 97:852-5. 2006
    ..There was a small effect on perceived quality of life but this was not reflected in other variables that measured the treatment response more directly...
  86. ncbi request reprint Relevance of positive patch-test reactions to fragrance mix
    Steven A Devos
    Department of Dermatology, Hospital H Serruys, Ostend, Belgium
    Dermatitis 19:43-7. 2008
    ..We presume that the traditional fragrance mix (FM) detects 70 to 80% of fragrance-allergic patients. FM has an irritant potential. Weak positive reactions may have a greater chance of being irrelevant than strong reactions...