Michiel E Adriaens

Summary

Affiliation: Maastricht University
Country: The Netherlands

Publications

  1. pmc Computational modelling of cancerous mutations in the EGFR/ERK signalling pathway
    Richard J Orton
    Institute of Comparative Medicine, Faculty of Veterinary Medicine, University of Glasgow, Glasgow, UK
    BMC Syst Biol 3:100. 2009
  2. pmc The public road to high-quality curated biological pathways
    Michiel E Adriaens
    Department of Bioinformatics BiGCaT, Maastricht University, Universiteitssingel 40, 6229ER Maastricht, The Netherlands
    Drug Discov Today 13:856-62. 2008
  3. pmc User-friendly solutions for microarray quality control and pre-processing on ArrayAnalysis.org
    Lars M T Eijssen
    Department of Bioinformatics BiGCaT, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    Nucleic Acids Res 41:W71-6. 2013
  4. pmc A user-friendly workflow for analysis of Illumina gene expression bead array data available at the arrayanalysis.org portal
    Lars M T Eijssen
    Department of Bioinformatics BiGCaT, Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands
    BMC Genomics 16:482. 2015
  5. pmc Molecular pathways involved in prostate carcinogenesis: insights from public microarray datasets
    Sarah C Baetke
    Department of Bioinformatics BiGCaT, Maastricht University, Maastricht, The Netherlands
    PLoS ONE 7:e49831. 2012
  6. pmc Quantitative analysis of ChIP-seq data uncovers dynamic and sustained H3K4me3 and H3K27me3 modulation in cancer cells under hypoxia
    Michiel E Adriaens
    Maastricht Centre for Systems Biology MaCSBio, Maastricht University, Maastricht, The Netherlands Department of Bioinformatics BiGCaT, Maastricht University, Maastricht, The Netherlands
    Epigenetics Chromatin 9:48. 2016
  7. pmc An evaluation of two-channel ChIP-on-chip and DNA methylation microarray normalization strategies
    Michiel E Adriaens
    Department of Bioinformatics BiGCaT, Maastricht University, Maastricht, The Netherlands
    BMC Genomics 13:42. 2012

Collaborators

  • S L M Coort
  • Thomas Kelder
  • Lars M T Eijssen
  • Chris T Evelo
  • Sarah C Baetke
  • Richard J Orton
  • Varshna S Goelela
  • Marijana Radonjic
  • Magali Jaillard
  • Stan Gaj
  • Philip J de Groot
  • Michael Muller
  • Renaud Seigneuric
  • Walter Kolch
  • David R Gilbert
  • Oliver E Sturm
  • Amelie Gormand

Detail Information

Publications7

  1. pmc Computational modelling of cancerous mutations in the EGFR/ERK signalling pathway
    Richard J Orton
    Institute of Comparative Medicine, Faculty of Veterinary Medicine, University of Glasgow, Glasgow, UK
    BMC Syst Biol 3:100. 2009
    ..In this study, we have used computational modelling techniques to investigate what effects various cancerous alterations have on the signalling flow through the ERK pathway...
  2. pmc The public road to high-quality curated biological pathways
    Michiel E Adriaens
    Department of Bioinformatics BiGCaT, Maastricht University, Universiteitssingel 40, 6229ER Maastricht, The Netherlands
    Drug Discov Today 13:856-62. 2008
    ..We applied this procedure to construct high-quality curated biological pathways involved in human fatty acid metabolism...
  3. pmc User-friendly solutions for microarray quality control and pre-processing on ArrayAnalysis.org
    Lars M T Eijssen
    Department of Bioinformatics BiGCaT, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    Nucleic Acids Res 41:W71-6. 2013
    ..Providing the scientific community with this easily accessible tool will allow improving data quality and reuse and adoption of standards. ..
  4. pmc A user-friendly workflow for analysis of Illumina gene expression bead array data available at the arrayanalysis.org portal
    Lars M T Eijssen
    Department of Bioinformatics BiGCaT, Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands
    BMC Genomics 16:482. 2015
    ..As a modular open source project, it allows developers to contribute modules that provide support for additional types of data or extend workflows...
  5. pmc Molecular pathways involved in prostate carcinogenesis: insights from public microarray datasets
    Sarah C Baetke
    Department of Bioinformatics BiGCaT, Maastricht University, Maastricht, The Netherlands
    PLoS ONE 7:e49831. 2012
    ....
  6. pmc Quantitative analysis of ChIP-seq data uncovers dynamic and sustained H3K4me3 and H3K27me3 modulation in cancer cells under hypoxia
    Michiel E Adriaens
    Maastricht Centre for Systems Biology MaCSBio, Maastricht University, Maastricht, The Netherlands Department of Bioinformatics BiGCaT, Maastricht University, Maastricht, The Netherlands
    Epigenetics Chromatin 9:48. 2016
    ..Where traditionally ChIP-seq data are often treated as dichotomous data, the model and experiment here necessitate a quantitative, data-driven analysis of both datasets...
  7. pmc An evaluation of two-channel ChIP-on-chip and DNA methylation microarray normalization strategies
    Michiel E Adriaens
    Department of Bioinformatics BiGCaT, Maastricht University, Maastricht, The Netherlands
    BMC Genomics 13:42. 2012
    ....