Affiliation: Leiden University Medical Center
Country: The Netherlands
- SSRI treatment of borderline personality disorder: a randomized, placebo-controlled clinical trial for female patients with borderline personality disorderThomas Rinne
Department of Psychiatry, Leiden University Medical Center, University of Leiden, PO Box 9600, 2300 RC Leiden, The Netherlands
Am J Psychiatry 159:2048-54. 2002..It was, therefore, decided to conduct a new randomized trial with a larger study group...
- Fluvoxamine reduces responsiveness of HPA axis in adult female BPD patients with a history of sustained childhood abuseThomas Rinne
Leiden University Medical Center, Department of Psychiatry, Netherlands
Neuropsychopharmacology 28:126-32. 2003..In conclusion, Fluvoxamine treatment reduces the hyperresponsiveness of the HPA axis in BPD patients with a history of sustained childhood abuse. This effect is likely to be obtained in the first 6 weeks of treatment...
- Hyperresponsiveness of hypothalamic-pituitary-adrenal axis to combined dexamethasone/corticotropin-releasing hormone challenge in female borderline personality disorder subjects with a history of sustained childhood abuseThomas Rinne
GGZ Buitenamstel, Department of Psychiatry, Free University Amsterdam, The Netherlands
Biol Psychiatry 52:1102-12. 2002..In humans, PTSD and MDD are associated with decreased and increased resistance to glucocorticoid feedback, respectively, which might reflect persistent changes in neuroendocrine sequelae following childhood abuse...
- Trauma exposure and hypothalamic-pituitary- adrenal axis functioning in mentally healthy Dutch peacekeeping veterans, 10-25 years after deploymentEllen R Klaassens
Department of Psychiatry, Leiden University Medical Center LUMC, Leiden, The Netherlands
J Trauma Stress 23:124-31. 2010..The authors concluded that this study does not support the idea that HPA-axis functioning is durably altered by trauma exposure during adulthood in men...