Image Sciences Institute

Summary

Organization: Image Sciences Institute
Country: The Netherlands

Top Publications

  1. doi Semi-automatic construction of reference standards for evaluation of image registration
    K Murphy
    Image Sciences Institute, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands
    Med Image Anal 15:71-84. 2011
  2. ncbi A computer-aided diagnosis system for detection of lung nodules in chest radiographs with an evaluation on a public database
    Arnold M R Schilham
    Image Sciences Institute, University Medical Center Utrecht, The Netherlands
    Med Image Anal 10:247-58. 2006
  3. ncbi Level set based cerebral vasculature segmentation and diameter quantification in CT angiography
    R Manniesing
    Department of Radiology, Image Sciences Institute, University Medical Center Utrecht, Heidelberglaan 100, Room E01 335, 3584 CX Utrecht, The Netherlands
    Med Image Anal 10:200-14. 2006
  4. ncbi Accuracy evaluation of direct navigation with an isocentric 3D rotational X-ray system
    Everine B van de Kraats
    Image Sciences Institute, University Medical Center Utrecht, Q0S 459, P O Box 85500, 3508 GA Utrecht, The Netherlands
    Med Image Anal 10:113-24. 2006
  5. ncbi Toward automated segmentation of the pathological lung in CT
    Ingrid Sluimer
    Image Sciences Institute, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands
    IEEE Trans Med Imaging 24:1025-38. 2005
  6. ncbi Probabilistic segmentation of brain tissue in MR imaging
    Petronella Anbeek
    Department of Radiology, Image Sciences Institute, University Medical Center Utrecht, Heidelberglaan 100, rm E01 335, 3584 CX Utrecht, The Netherlands
    Neuroimage 27:795-804. 2005
  7. ncbi Automatic detection of red lesions in digital color fundus photographs
    Meindert Niemeijer
    Image Sciences Institute Q0S 459, Heidelberglaan 100, 3584CX, Utrecht, The Netherlands
    IEEE Trans Med Imaging 24:584-92. 2005
  8. ncbi Segmentation of thrombus in abdominal aortic aneurysms from CTA with nonparametric statistical grey level appearance modeling
    Silvia D Olabarriaga
    University Medical Center Utrecht, Image Sciences Institute, Q S 459, Heidelberglaan 100, 3584CX Utrecht, The Netherlands
    IEEE Trans Med Imaging 24:477-85. 2005
  9. ncbi Brain shift estimation in image-guided neurosurgery using 3-D ultrasound
    Marloes M J Letteboer
    Image Sciences Institute, University Medical Center, 3584 CX Utrecht, The Netherlands
    IEEE Trans Biomed Eng 52:268-76. 2005
  10. ncbi Analysis and correction of gradient nonlinearity and B0 inhomogeneity related scaling errors in two-dimensional phase contrast flow measurements
    Johannes M Peeters
    Image Sciences Institute, Department of Radiology, University Medical Center Utrecht, Room E01 335, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Magn Reson Med 53:126-33. 2005

Scientific Experts

  • Bram van Ginneken
  • Meindert Niemeijer
  • Remko van der Weide
  • Rashindra Manniesing
  • Ingrid Sluimer
  • Ivana Isgum
  • Joes Staal
  • Evert Jan Vonken
  • Marius Staring
  • Stefan Klein
  • Marco Loog
  • Cynthia Jongen
  • Onno Wink
  • Yulia Arzhaeva
  • Brendan Vastenhouw
  • M Kluytmans
  • Tanja Alderliesten
  • M A Viergever
  • Matthias J P van Osch
  • Max A Viergever
  • Chris J G Bakker
  • Jeroen van der Grond
  • Petronella Anbeek
  • K Murphy
  • W J Niessen
  • Wiro J Niessen
  • Paul A M Smeets
  • Johannes M Peeters
  • Arnold M R Schilham
  • Jan Henry Seppenwoolde
  • Lambertus W Bartels
  • Koen L Vincken
  • M D Abramoff
  • Sandra A P Cornelissen
  • B J de Hoop
  • Tos T J M Berendschot
  • Sara M Sprinkhuizen
  • Mathias Prokop
  • Annette Stafleu
  • Cees de Graaf
  • Wojciech Zbijewski
  • Everine B van de Kraats
  • C J Bakker
  • Marloes M J Letteboer
  • Silvia D Olabarriaga
  • G P Penney
  • Robertus H C Bisschops
  • Cornelis M van Bemmel
  • Shirley A M Baert
  • F J Beekman
  • Dirk van Norren
  • M J P van Osch
  • Michael D Abramoff
  • Niels P A Zagers
  • B M ter Haar Romeny
  • A F Frangi
  • C Bos
  • M J van Osch
  • T J Berendschot
  • E H Meijering
  • W P Mali
  • J P W Pluim
  • Miraude E Adriaensen
  • Hence J Verhagen
  • Martijn J van der Bom
  • Maurits K Konings
  • Frans L Moll
  • M K Konings
  • A M R Schilham
  • H A Gietema
  • R Stokking
  • M Prokop
  • Solrun Vidarsdottir
  • Ernst E H van Faassen
  • Hanno Pijl
  • Freek J Beekman
  • Lance Kendrick
  • Rutger A J Nievelstein
  • Theo van Walsum
  • Hester Gietema
  • Niels J Noordhoek
  • C Kamphuis
  • Marcel Breeuwer
  • Johannes F W Nijsen
  • Jean Michel Rouet
  • Glenda S van Bochove
  • Peter W A Willems
  • Clemens Bos
  • Sander W Zielhuis
  • Alfred D van Het Schip

Detail Information

Publications62

  1. doi Semi-automatic construction of reference standards for evaluation of image registration
    K Murphy
    Image Sciences Institute, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands
    Med Image Anal 15:71-84. 2011
    ..The utility of the reference standard data as a tool in evaluating registration is shown by the comparison of six sets of registration results on the 47 pairs of thoracic CT data...
  2. ncbi A computer-aided diagnosis system for detection of lung nodules in chest radiographs with an evaluation on a public database
    Arnold M R Schilham
    Image Sciences Institute, University Medical Center Utrecht, The Netherlands
    Med Image Anal 10:247-58. 2006
    ..For four false positives, this increases to 67%. This is close to the previously reported 70% detection rate of the radiologists...
  3. ncbi Level set based cerebral vasculature segmentation and diameter quantification in CT angiography
    R Manniesing
    Department of Radiology, Image Sciences Institute, University Medical Center Utrecht, Heidelberglaan 100, Room E01 335, 3584 CX Utrecht, The Netherlands
    Med Image Anal 10:200-14. 2006
    ....
  4. ncbi Accuracy evaluation of direct navigation with an isocentric 3D rotational X-ray system
    Everine B van de Kraats
    Image Sciences Institute, University Medical Center Utrecht, Q0S 459, P O Box 85500, 3508 GA Utrecht, The Netherlands
    Med Image Anal 10:113-24. 2006
    ..The individual steps in the registration procedure are explained and evaluated. The acquired navigation accuracy using this coupling is approximately one millimeter...
  5. ncbi Toward automated segmentation of the pathological lung in CT
    Ingrid Sluimer
    Image Sciences Institute, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands
    IEEE Trans Med Imaging 24:1025-38. 2005
    ..The refined registration scheme enjoys the additional benefit that it does not require pathological (hand-segmented) training data...
  6. ncbi Probabilistic segmentation of brain tissue in MR imaging
    Petronella Anbeek
    Department of Radiology, Image Sciences Institute, University Medical Center Utrecht, Heidelberglaan 100, rm E01 335, 3584 CX Utrecht, The Netherlands
    Neuroimage 27:795-804. 2005
    ..Evaluation with respect to the gold standard showed that the SI-values for all tissues exceeded 0.8 and all PSI-values exceeded 0.7, implying an excellent agreement...
  7. ncbi Automatic detection of red lesions in digital color fundus photographs
    Meindert Niemeijer
    Image Sciences Institute Q0S 459, Heidelberglaan 100, 3584CX, Utrecht, The Netherlands
    IEEE Trans Med Imaging 24:584-92. 2005
    ..The method is compared with several different automatic systems and is shown to outperform them all. Performance is close to that of a human expert examining the images for the presence of red lesions...
  8. ncbi Segmentation of thrombus in abdominal aortic aneurysms from CTA with nonparametric statistical grey level appearance modeling
    Silvia D Olabarriaga
    University Medical Center Utrecht, Image Sciences Institute, Q S 459, Heidelberglaan 100, 3584CX Utrecht, The Netherlands
    IEEE Trans Med Imaging 24:477-85. 2005
    ..Results obtained in a study of 17 patients show that the agreement with respect to manual segmentations is comparable to previous values reported in the literature, with considerable less user interaction...
  9. ncbi Brain shift estimation in image-guided neurosurgery using 3-D ultrasound
    Marloes M J Letteboer
    Image Sciences Institute, University Medical Center, 3584 CX Utrecht, The Netherlands
    IEEE Trans Biomed Eng 52:268-76. 2005
    ..Brain shift can be detected by acquiring 3-D ultrasound data during image-guided neurosurgery. Therefore, it can be used as a basis for correcting image data and preoperative planning for intraoperative deformations...
  10. ncbi Analysis and correction of gradient nonlinearity and B0 inhomogeneity related scaling errors in two-dimensional phase contrast flow measurements
    Johannes M Peeters
    Image Sciences Institute, Department of Radiology, University Medical Center Utrecht, Room E01 335, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Magn Reson Med 53:126-33. 2005
    ..Correction of the off-center flow values with the local scaling factors and the concomitant gradient phase improves the measurement accuracy substantially, both in the flow phantom and in a volunteer study...
  11. ncbi Internal radiation therapy of liver tumors: qualitative and quantitative magnetic resonance imaging of the biodistribution of holmium-loaded microspheres in animal models
    Jan Henry Seppenwoolde
    Image Sciences Institute, Department of Radiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Magn Reson Med 53:76-84. 2005
    ..The observed underestimation is tentatively attributed to accumulations of HoMS in larger liver vessels. The exploratory quantification experiments suggest the feasibility of MR dosimetry...
  12. ncbi Construction and evaluation of an average CT brain image for inter-subject registration
    Cynthia Jongen
    Image Sciences Institute, University Medical Center Utrecht, Room E01 335, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Comput Biol Med 34:647-62. 2004
    ..Registration of new images to the average CT is more consistent than registration to a single CT image. The use of the average CT image is illustrated...
  13. ncbi Automatic segmentation of different-sized white matter lesions by voxel probability estimation
    Petronella Anbeek
    Department of Radiology, Image Sciences Institute, University Medical Center Utrecht, Heidelberglaan 100, rm E01 335, 3584 CX Utrecht, The Netherlands
    Med Image Anal 8:205-15. 2004
    ..Furthermore, it is suitable for detection of WMLs in large and longitudinal population studies...
  14. ncbi Objective determination of the macular pigment optical density using fundus reflectance spectroscopy
    Tos T J M Berendschot
    Department of Ophthalmology, University Medical Center Utrecht, The Netherlands
    Arch Biochem Biophys 430:149-55. 2004
    ..This paper discusses the technique and reviews measurements, including the observed absence of an age effect...
  15. ncbi Local noise weighted filtering for emphysema scoring of low-dose CT images
    Arnold M R Schilham
    Image Sciences Institute, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    IEEE Trans Med Imaging 25:451-63. 2006
    ..NOVA filtering of a CT image of typically 400 x 512 x 512 voxels takes only a couple of minutes which makes it suitable for routine use in clinical practice...
  16. ncbi Effect of satiety on brain activation during chocolate tasting in men and women
    Paul A M Smeets
    Image Sciences Institute and the Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands
    Am J Clin Nutr 83:1297-305. 2006
    ..A key factor controlling food intake is selective satiety, ie, the phenomenon that the motivation to eat more of a food decreases more than does the motivation to eat foods not eaten...
  17. ncbi Efficient Monte Carlo based scatter artifact reduction in cone-beam micro-CT
    Wojciech Zbijewski
    Department of Nuclear Medicine, Image Sciences Institute, Rudolf Magnus Institute of Neuroscience, STR5 203 3584 CG Utrecht, The Netherlands
    IEEE Trans Med Imaging 25:817-27. 2006
    ..In conclusion, a general, accurate, and efficient scatter correction algorithm is developed that requires no mechanical modifications of the scanning equipment and results in only a moderate increase in the total reconstruction time...
  18. doi Temperature-induced tissue susceptibility changes lead to significant temperature errors in PRFS-based MR thermometry during thermal interventions
    Sara M Sprinkhuizen
    Image Sciences Institute Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Magn Reson Med 64:1360-72. 2010
    ..The results of the experiments and simulations showed that the temperature-induced susceptibility changes of water and fat lead to significant errors in proton resonance frequency shift-based MR thermometry...
  19. doi Detection of occult endoleaks after endovascular treatment of abdominal aortic aneurysm using magnetic resonance imaging with a blood pool contrast agent: preliminary observations
    Sandra A P Cornelissen
    Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Invest Radiol 45:548-53. 2010
    ..To determine whether blood pool contrast agent-enhanced magnetic resonance imaging (MRI) can visualize endoleaks that are occult on computed tomography (CT) in patients with nonshrinking aneurysms after endovascular aneurysm repair...
  20. ncbi Automated aortic calcium scoring on low-dose chest computed tomography
    Ivana Isgum
    Image Sciences Institute, University Medical Center Utrecht, Utrecht 3584 CX, The Netherlands
    Med Phys 37:714-23. 2010
    ..The authors developed and evaluated a computer-aided system for automatic detection and quantification of aortic calcifications in low-dose noncontrast-enhanced chest CT...
  21. pmc Fast detection of the optic disc and fovea in color fundus photographs
    Meindert Niemeijer
    Department of Ophthalmology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Med Image Anal 13:859-70. 2009
    ..The method found the optic disc in 99.4% and the fovea in 96.8% of regular screening images and for the images with abnormalities these numbers were 93.0% and 89.0% respectively...
  22. doi A large-scale evaluation of automatic pulmonary nodule detection in chest CT using local image features and k-nearest-neighbour classification
    K Murphy
    Image Sciences Institute, University Medical Center, Utrecht, The Netherlands
    Med Image Anal 13:757-70. 2009
    ..2 false-positives per scan is achieved. The detection results presented are a realistic measure of a CAD system performance in a low-dose screening study which includes a diverse array of nodules of many varying sizes, types and textures...
  23. doi Information fusion for diabetic retinopathy CAD in digital color fundus photographs
    Meindert Niemeijer
    Department of Electrical and Computer Engineering, University of Iowa, Iowa City, IA 52242 USA
    IEEE Trans Med Imaging 28:775-85. 2009
    ..The best performing fusion method obtained an area under the receiver operator characteristic curve of 0.881. This indicates that automated prescreening could be applied in diabetic retinopathy screening programs...
  24. doi Multi-atlas-based segmentation with local decision fusion--application to cardiac and aortic segmentation in CT scans
    Ivana Isgum
    Department of Radiology, Image Sciences Institute, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands
    IEEE Trans Med Imaging 28:1000-10. 2009
    ..Moreover, the additional atlas selection step led to a faster segmentation at a comparable performance...
  25. doi Linear dimensionality reduction via a heteroscedastic extension of LDA: the Chernoff criterion
    Marco Loog
    Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands
    IEEE Trans Pattern Anal Mach Intell 26:732-9. 2004
    ..This criterion combines separation information present in the class mean as well as the class covariance matrices. Extensive experiments and a comparison with similar dimension reduction techniques are presented...
  26. ncbi Nonrigid registration with tissue-dependent filtering of the deformation field
    Marius Staring
    Image Sciences Institute, University Medical Center Utrecht, PO Box 85500, 3508 GA, Room Q0S 459, Utrecht, The Netherlands
    Phys Med Biol 52:6879-92. 2007
    ..The results show that tissue-dependent filtering of the deformation field leads to improved registration results: tumour volumes and vessel widths are preserved rather than affected...
  27. ncbi Oral glucose intake inhibits hypothalamic neuronal activity more effectively than glucose infusion
    Paul A M Smeets
    University Medical Center Utrecht, Image Sciences Institute, Heidelberglaan 100, Rm Q0S 459, 3584 CX Utrecht, The Netherlands
    Am J Physiol Endocrinol Metab 293:E754-8. 2007
    ..1). We infer that neural and endocrine signals emanating from the gastrointestinal tract are critical for the hypothalamic response to nutrient ingestion...
  28. ncbi Image structure clustering for image quality verification of color retina images in diabetic retinopathy screening
    Meindert Niemeijer
    University Medical Center Utrecht, Image Sciences Institute, Q0S 459, Heidelberglaan 100, 3584CX, Utrecht, The Netherlands
    Med Image Anal 10:888-98. 2006
    ..The best system, based on a Support Vector Machine, has performance close to optimal with an area under the ROC curve of 0.9968...
  29. ncbi Automatic rib segmentation and labeling in computed tomography scans using a general framework for detection, recognition and segmentation of objects in volumetric data
    Joes Staal
    Image Sciences Institute, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Med Image Anal 11:35-46. 2007
    ..8%, specificity is 97.8%). After grouping, 98.4% of the ribs are recognized. The final segmentation is qualitatively evaluated and is very accurate for over 80% of all ribs, with slight errors otherwise...
  30. ncbi Magnetic resonance imaging of phase transitions in nitinol
    Johannes M Peeters
    Department of Radiology, Image Sciences Institute, University Medical Center Utrecht, Heidelberglaan 100, Rm Q0S 459, 3584 CX Utrecht, The Netherlands
    J Biomed Mater Res A 80:938-45. 2007
    ..The results indicate the potential of magnetic resonance imaging to provide direct feedback of the thermomechanical state of the alloy...
  31. ncbi Analysis of cerebral infarction pattern in computed tomography images of patients with internal carotid artery stenosis
    Cynthia Jongen
    Image Sciences Institute, University Medical Center Utrecht, The Netherlands
    Invest Radiol 39:462-9. 2004
    ..An unbiased and quantitative analysis of lesion patterns in patient groups is described and applied to the analysis of infarction patterns...
  32. ncbi Registration-based interpolation
    G P Penney
    Image Sciences Institute, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands
    IEEE Trans Med Imaging 23:922-6. 2004
    ..Results show that the proposed method statistically significantly outperforms both linear and shape-based interpolation...
  33. ncbi Correcting partial volume artifacts of the arterial input function in quantitative cerebral perfusion MRI
    M J van Osch
    Department of Radiology, Image Sciences Institute, University Hospital Utrecht, Utrecht, The Netherlands
    Magn Reson Med 45:477-85. 2001
    ..This correction is shown to be accurate at low spatial resolutions for phantom data and to improve the AIF determination in a clinical example. Magn Reson Med 45:477-485, 2001...
  34. ncbi Quantitative analysis of vascular morphology from 3D MR angiograms: In vitro and in vivo results
    A F Frangi
    Image Sciences Institute, University Medical Center, Utrecht, The Netherlands
    Magn Reson Med 45:311-22. 2001
    ..001) between the manual scores and DSA. From the results it can be concluded that the approach is a promising objective technique to assess geometrical vascular parameters, including degree of stenosis. Magn Reson Med 45:311-322, 2001...
  35. ncbi Registration, segmentation, and visualization of multimodal brain images
    M A Viergever
    Image Sciences Institute, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Comput Med Imaging Graph 25:147-51. 2001
    ..The state-of-the-art in these areas is discussed and suggestions for future research are given...
  36. ncbi Objective quantification of the motion of soft tissues in the orbit
    M D Abramoff
    Department of Ophthalmology and the Image Sciences Institute, University Medical Center Utrecht, The Netherlands
    IEEE Trans Med Imaging 19:986-95. 2000
    ..Motion in the orbit ranged between 0.05 and 0.25 mm/degree gaze. Color-coding was found to be attractive as a visualization technique, because it shows both magnitude and orientation of all flow vectors without cluttering...
  37. ncbi Automatic segmentation of lung fields in chest radiographs
    B van Ginneken
    Image Sciences Institute, Utrecht University, The Netherlands
    Med Phys 27:2445-55. 2000
    ..The average accuracy of the scheme is 0.969 +/- 0.0080, which is close to the interobserver variability of 0.984 +/- 0.0048. The methods are fast, and implemented on a standard PC platform...
  38. ncbi On-line flow quantification by low-resolution phase-contrast MR imaging and model-based postprocessing
    R van der Weide
    Image Sciences Institute, Department of Radiology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands
    J Magn Reson Imaging 12:623-31. 2000
    ..The capabilities of the presented approach are illustrated by the results of several hypercapnia experiments and carotid compression tests performed on healthy volunteers...
  39. ncbi Heating around intravascular guidewires by resonating RF waves
    M K Konings
    Department of Radiology, Image Sciences Institute, University Hospital Utrecht, The Netherlands
    J Magn Reson Imaging 12:79-85. 2000
    ..The capricious dependencies of this resonance phenomenon on environmental factors have severe consequences for predictability and safety guidelines...
  40. ncbi Fast delineation and visualization of vessels in 3-D angiographic images
    O Wink
    Image Sciences Institute, University Medical Center Utrecht, The Netherlands
    IEEE Trans Med Imaging 19:337-46. 2000
    ..In all applications, a long stretch of vessels with varying width is tracked, delineated, and visualized, in less than 10 s on a standard clinical workstation...
  41. ncbi Simultaneous quantitative cerebral perfusion and Gd-DTPA extravasation measurement with dual-echo dynamic susceptibility contrast MRI
    E P Vonken
    Image Sciences Institute, University Hospital Utrecht, Utrecht, The Netherlands
    Magn Reson Med 43:820-7. 2000
    ..It is applicable whether extravasation occurs or not. When extravasation is present, application of the proposed method is mandatory for accurate cerebral blood volume measurements. Magn Reson Med 43:820-827, 2000...
  42. ncbi Estimation of the depth-dependent component of the point spread function of SPECT
    F J Beekman
    Imaging Sciences Institute, University Hospital Utrecht, The Netherlands
    Med Phys 26:2311-22. 1999
    ..The corrected responses have the desired shapes and simulated responses closely resemble measured responses. The proposed methodology may, consequently, serve as a basis for accurate three-dimensional (3D) SPECT reconstruction...
  43. ncbi Accelerated iterative transmission CT reconstruction using an ordered subsets convex algorithm
    C Kamphuis
    Image Sciences Institute, University Hospital Utrecht, The Netherlands
    IEEE Trans Med Imaging 17:1101-5. 1998
    ..Images and image profiles of the reconstructions were in good agreement. In conclusion, OSC and the convex algorithm result in similar image quality but OSC is more than an order of magnitude faster...
  44. pmc Advances in three-dimensional diagnostic radiology
    B M ter Haar Romeny
    Image Sciences Institute, Utrecht University, The Netherlands
    J Anat 193:363-71. 1998
    ..This paper reviews recent work in this area from the Image Sciences Institute at Utrecht University. The processes that yield a useful visual presentation are sequential...
  45. ncbi CTA-based angle selection for diagnostic and interventional angiography of saccular intracranial aneurysms
    R van der Weide
    Image Sciences Institute, University Hospital Utrecht, The Netherlands
    IEEE Trans Med Imaging 17:831-41. 1998
    ....
  46. ncbi MRA of hemodialysis access grafts and fistulae using selective contrast injection and flow interruption
    C Bos
    Department of Radiology, Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands
    Magn Reson Med 45:557-61. 2001
    ..When filling is satisfactory, a 3D acquisition is started. The feasibility of this selective contrast-enhanced MR angiography technique is demonstrated in four Cimino-fistulae and four PTFE grafts. Magn Reson Med 45:557-561, 2001...
  47. ncbi Wavelength dependence of the Stiles-Crawford effect explained by perception of backscattered light from the choroid
    T J Berendschot
    Department of Ophthalmology, University Medical Center Utrecht, The Netherlands
    J Opt Soc Am A Opt Image Sci Vis 18:1445-51. 2001
    ..The wavelength dependence of the Stiles-Crawford effect could be well described with the geometrical optics model. Essential elements are self-screening and the inclusion of backscattered choroidal light for perception...
  48. ncbi Quantitative evaluation of convolution-based methods for medical image interpolation
    E H Meijering
    Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands
    Med Image Anal 5:111-26. 2001
    ..In the evaluation we use images from a wide variety of medical image modalities. The results show that spline interpolation is to be preferred over all other methods, both for its accuracy and its relatively low computational cost...
  49. ncbi The MDF discrimination measure: Fisher in disguise
    Marco Loog
    Image Sciences Institute, University Medical Center Utrecht, HP E01 334, P O Box 85500, 3508 GA Utrecht, The Netherlands
    Neural Netw 17:563-6. 2004
    ..The effect of unequal priors on the efficiency of the measures is also discussed...
  50. ncbi Semiautomatic segmentation and stenosis quantification of 3D contrast-enhanced MR angiograms of the internal carotid artery
    Cornelis M van Bemmel
    Image Sciences Institute, University Medical Center, Utrecht, The Netherlands
    Magn Reson Med 51:753-60. 2004
    ..The technique was applied to 20 ICAs. The variation in measurements obtained by this method in comparison with manual observations was 8.7%, which is smaller than the interobserver variability among three experts (11.0%)...
  51. ncbi Probabilistic segmentation of white matter lesions in MR imaging
    Petronella Anbeek
    Department of Radiology, Image Sciences Institute, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands
    Neuroimage 21:1037-44. 2004
    ..This method for automated WML segmentation reaches an accuracy that is comparable to methods for multiple sclerosis (MS) lesion segmentation and is suitable for detection of WMLs in large and longitudinal population studies...
  52. ncbi Passive tracking exploiting local signal conservation: the white marker phenomenon
    Jan Henry Seppenwoolde
    Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands
    Magn Reson Med 50:784-90. 2003
    ....
  53. ncbi Model of the human vasculature for studying the influence of contrast injection speed on cerebral perfusion MRI
    Matthias J P van Osch
    Department of Radiology, Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands
    Magn Reson Med 50:614-22. 2003
    ..Additionally, it was determined that decreasing the temporal resolution of the acquisition results in an underestimation of the CBF values, and an increase of the standard deviation (SD) of CBF measurements...
  54. ncbi Guide-wire tracking during endovascular interventions
    Shirley A M Baert
    Image Sciences Institute, University Medical Center Utrecht, Heidelberglaan 100, Room E 01 334, 3584 CX Utrecht, The Netherlands
    IEEE Trans Med Imaging 22:965-72. 2003
    ..Using the automatic method, the guide wire could be tracked in 96% of the frames, with a similar accuracy to three observers, although the position of the tip was estimated less accurately...
  55. ncbi Measuring the arterial input function with gradient echo sequences
    Matthias J P van Osch
    Department of Radiology, Image Sciences Institute, University Medical Center Utrecht, The Netherlands
    Magn Reson Med 49:1067-76. 2003
    ....
  56. ncbi Quantitative cerebral perfusion MRI and CO2 reactivity measurements in patients with symptomatic internal carotid artery occlusion
    M J P van Osch
    Image Sciences Institute, Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Neuroimage 17:469-78. 2002
    ..Our results indicate that an increase in TBP reflects a poor development of collateral flow, which is supported by a relatively low CO2 reactivity in these patients...
  57. ncbi Simultaneous measurement of foveal spectral reflectance and cone-photoreceptor directionality
    Niels P A Zagers
    Department of Ophthalmology, University Medical Center Utrecht, The Netherlands
    Appl Opt 41:4686-96. 2002
    ..As an example, macular pigment and melanin are discussed in more detail. Spatial profiles exhibited the optical Stiles-Crawford effect, reflecting cone-photoreceptor directionality...
  58. ncbi Rectus extraocular muscle paths and decompression surgery for Graves orbitopathy: mechanism of motility disturbances
    Michael D Abramoff
    Department of Ophthalmology, University Medical Center Utrecht, Utrecht, The Netherlands
    Invest Ophthalmol Vis Sci 43:300-7. 2002
    ..To study possible causes of motility disturbances that may result from orbital decompression surgery in patients with Graves orbitopathy and especially the role of rectus extraocular muscle paths...
  59. ncbi Computer-aided diagnosis in chest radiography: a survey
    B van Ginneken
    Image Sciences Institute, University Medical Center Utrecht, The Netherlands
    IEEE Trans Med Imaging 20:1228-41. 2001
    ..Remaining challenges are indicated and some directions for future research are given...
  60. ncbi Localization of intravascular devices with paramagnetic markers in MR images
    R van der Weide
    Image Sciences Institute, Department of Radiology, University Medical Center Utrecht, The Netherlands
    IEEE Trans Med Imaging 20:1061-71. 2001
    ..Results of an animal experiment and of a clinical application are demonstrated. Validation in phantom experiments shows that the method is able to localize the device in 95% of the cases...
  61. ncbi Patients with persistent pain after enucleation studied by MRI dynamic color mapping and histopathology
    M D Abramoff
    Department of Ophthalmology, University Medical Center Utrecht, The Netherlands
    Invest Ophthalmol Vis Sci 42:2188-92. 2001
    ..To study possible causes of persistent pain in patients who underwent enucleation of the globe and in whom all other noninvasively detectable causes of pain had been ruled out...
  62. ncbi Geodesic deformable models for medical image analysis
    W J Niessen
    Image Sciences Institute, University Hospital Utrecht, The Netherlands
    IEEE Trans Med Imaging 17:634-41. 1998
    ..g. due to partial volume effects, noise, or motion artifacts, they do not perform well, since the approach is completely data-driven...