Anouk van de Winkel
Affiliation: Erasmus MC
Country: The Netherlands
- Digestive disease week 2011: highlights of clinical and preclinical research on Barrett's esophagus and associated esophageal adenocarcinomaA van de Winkel
Department of Gastroenterology and Hepatology, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands
Dis Esophagus 26:130-40. 2013..We also discuss the relevance and impact of these findings on the future of BE and EAC research...
- Differential expression of the nuclear receptors farnesoid X receptor (FXR) and pregnane X receptor (PXR) for grading dysplasia in patients with Barrett's oesophagusAnouk van de Winkel
Department of Gastroenterology and Hepatology, Erasmus MC University Medical Centre Rotterdam, Rotterdam, The Netherlands
Histopathology 58:246-53. 2011..To investigate expression of nuclear receptors farnesoid X receptor (FXR) and pregnane X receptor (PXR) as a diagnostic tool to improve grading of dysplasia in Barrett's oesophagus patients...
- Expression, localization and polymorphisms of the nuclear receptor PXR in Barrett's esophagus and esophageal adenocarcinomaAnouk van de Winkel
Department of Gastroenterology and Hepatology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands
BMC Gastroenterol 11:108. 2011..This study aimed to investigate the expression and genetic variation of PXR in reflux esophagitis (RE), Barrett's esophagus (BE) and esophageal adenocarcinoma...
- Bile acid-stimulated expression of the farnesoid X receptor enhances the immune response in Barrett esophagusAstrid Capello
Department of Gastroenterology and Hepatology, Erasmus Universiry Medical Center, Rotterdam, The Netherlands
Am J Gastroenterol 103:1510-6. 2008..FXR activation is also involved in the induction of the innate immune response. This suggests that FXR is involved in the pathogenesis and the inflammation seen in BE...
- Vitamin D Receptor Polymorphisms Are Associated with Reduced Esophageal Vitamin D Receptor Expression and Reduced Esophageal Adenocarcinoma RiskVincent T Janmaat
Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
Mol Med 21:346-54. 2015..We identified a VDR haplotype associated with reduced esophageal VDR expression and a reduced incidence of RE, BE and EAC. This VDR haplotype could be useful in identifying individuals who benefit most from vitamin D chemoprevention. ..