Aad van der Lugt

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. pmc MR CLEAN, a multicenter randomized clinical trial of endovascular treatment for acute ischemic stroke in the Netherlands: study protocol for a randomized controlled trial
    Puck S S Fransen
    Department of Neurology, Erasmus MC University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Trials 15:343. 2014
  2. ncbi request reprint Accuracy of CT angiography in the assessment of a fetal origin of the posterior cerebral artery
    A van der Lugt
    Department of Radiology, Erasmus MC, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Eur Radiol 14:1627-33. 2004
  3. pmc Atherosclerotic plaque volume and composition in symptomatic carotid arteries assessed with multidetector CT angiography; relationship with severity of stenosis and cardiovascular risk factors
    S Rozie
    Departments of Radiology, Erasmus MC, University Medical Center Rotterdam, s Gravendijkwal 230, Rotterdam 3015 CE, The Netherlands
    Eur Radiol 19:2294-301. 2009
  4. pmc Effects of intima stiffness and plaque morphology on peak cap stress
    Ali C Akyildiz
    Department of Biomedical Engineering, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    Biomed Eng Online 10:25. 2011
  5. ncbi request reprint Statistical analysis of structural brain connectivity
    Renske de Boer
    Biomedical Imaging Group Rotterdam, Department of Radiology, Erasmus MC, Rotterdam, The Netherlands
    Med Image Comput Comput Assist Interv 13:101-8. 2010
  6. doi request reprint Atherosclerotic calcification relates to cognitive function and to brain changes on magnetic resonance imaging
    Daniel Bos
    Department of Radiology, Erasmus MC, Rotterdam, The Netherlands
    Alzheimers Dement 8:S104-11. 2012
  7. ncbi request reprint Intravenous contrast material administration at 16-detector row helical CT coronary angiography: test bolus versus bolus-tracking technique
    Filippo Cademartiri
    Department of Radiology, Erasmus Medical Center, Dr Molenwaterplein 40, 3015 GD Rotterdam, The Netherlands
    Radiology 233:817-23. 2004
  8. doi request reprint Semiautomatic carotid lumen segmentation for quantification of lumen geometry in multispectral MRI
    Hui Tang
    Biomedical Imaging Group Rotterdam, Departments of Radiology and Medical Informatics, Erasmus MC, Rotterdam, The Netherlands
    Med Image Anal 16:1202-15. 2012
  9. pmc Assessment of atherosclerotic carotid plaque volume with multidetector computed tomography angiography
    Thomas T de Weert
    Department of Radiology, Erasmus MC, University Medical Center Rotterdam, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Int J Cardiovasc Imaging 24:751-9. 2008
  10. ncbi request reprint High iodine concentration contrast material for noninvasive multislice computed tomography coronary angiography: iopromide 370 versus iomeprol 400
    Filippo Cademartiri
    Department of Radiology, Thoraxcentrum, Erasmus Medical Center, Rotterdam, The Netherlands
    Invest Radiol 41:349-53. 2006

Collaborators

Detail Information

Publications97

  1. pmc MR CLEAN, a multicenter randomized clinical trial of endovascular treatment for acute ischemic stroke in the Netherlands: study protocol for a randomized controlled trial
    Puck S S Fransen
    Department of Neurology, Erasmus MC University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Trials 15:343. 2014
    ..Additionally, we aim to assess the safety of IAT, and the effect on recanalization of different mechanical treatment modalities...
  2. ncbi request reprint Accuracy of CT angiography in the assessment of a fetal origin of the posterior cerebral artery
    A van der Lugt
    Department of Radiology, Erasmus MC, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Eur Radiol 14:1627-33. 2004
    ..Positive and negative predictive values were 77 and 100%, respectively. CTA can be considered a valid diagnostic tool for the assessment of a fetal origin of the PCA in patients with a cerebral ischemic event in the territory of the PCA...
  3. pmc Atherosclerotic plaque volume and composition in symptomatic carotid arteries assessed with multidetector CT angiography; relationship with severity of stenosis and cardiovascular risk factors
    S Rozie
    Departments of Radiology, Erasmus MC, University Medical Center Rotterdam, s Gravendijkwal 230, Rotterdam 3015 CE, The Netherlands
    Eur Radiol 19:2294-301. 2009
    ..Luminal stenosis of the carotid artery partly reflects the amount of atherosclerotic carotid disease. Plaque volume and plaque composition are associated with cardiovascular risk factors...
  4. pmc Effects of intima stiffness and plaque morphology on peak cap stress
    Ali C Akyildiz
    Department of Biomedical Engineering, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    Biomed Eng Online 10:25. 2011
    ..A parametric study was conducted to assess the effect of intima stiffness and plaque morphology on peak cap stress...
  5. ncbi request reprint Statistical analysis of structural brain connectivity
    Renske de Boer
    Biomedical Imaging Group Rotterdam, Department of Radiology, Erasmus MC, Rotterdam, The Netherlands
    Med Image Comput Comput Assist Interv 13:101-8. 2010
    ..Principal component regression outperformed all other prediction models, demonstrating the age and gender information encoded in the connectivity network...
  6. doi request reprint Atherosclerotic calcification relates to cognitive function and to brain changes on magnetic resonance imaging
    Daniel Bos
    Department of Radiology, Erasmus MC, Rotterdam, The Netherlands
    Alzheimers Dement 8:S104-11. 2012
    ..This study investigates associations of atherosclerosis (measured using CT) at four locations with cognition and brain changes on magnetic resonance imaging (MRI)...
  7. ncbi request reprint Intravenous contrast material administration at 16-detector row helical CT coronary angiography: test bolus versus bolus-tracking technique
    Filippo Cademartiri
    Department of Radiology, Erasmus Medical Center, Dr Molenwaterplein 40, 3015 GD Rotterdam, The Netherlands
    Radiology 233:817-23. 2004
    ..To compare test bolus and bolus-tracking techniques for intravenous contrast material administration at 16-detector row computed tomographic (CT) coronary angiography...
  8. doi request reprint Semiautomatic carotid lumen segmentation for quantification of lumen geometry in multispectral MRI
    Hui Tang
    Biomedical Imaging Group Rotterdam, Departments of Radiology and Medical Informatics, Erasmus MC, Rotterdam, The Netherlands
    Med Image Anal 16:1202-15. 2012
    ..This demonstrates that the automated method can be used for replacing manual centerline annotation and manual contour drawing for lumen segmentation in MRIs data prior to quantifying the carotid bifurcation geometry...
  9. pmc Assessment of atherosclerotic carotid plaque volume with multidetector computed tomography angiography
    Thomas T de Weert
    Department of Radiology, Erasmus MC, University Medical Center Rotterdam, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Int J Cardiovasc Imaging 24:751-9. 2008
    ..Therefore, we evaluated a dedicated software tool for volume measurements of atherosclerotic carotid plaque and its components in multidetector computed tomography angiography (MDCTA) images...
  10. ncbi request reprint High iodine concentration contrast material for noninvasive multislice computed tomography coronary angiography: iopromide 370 versus iomeprol 400
    Filippo Cademartiri
    Department of Radiology, Thoraxcentrum, Erasmus Medical Center, Rotterdam, The Netherlands
    Invest Radiol 41:349-53. 2006
    ..The objective of this study was to compare intracoronary attenuation on 16-row multislice computed tomography (16-MSCT) coronary angiography using 2 contrast materials (CM) with high iodine concentration...
  11. doi request reprint Assessment of feasibility of endovascular treatment of ruptured intracranial aneurysms with 16-detector row CT angiography
    Mathieu van der Jagt
    Department of Neurology, Erasmus MC, Rotterdam, The Netherlands
    Cerebrovasc Dis 26:482-8. 2008
    ..It is unclear whether 16-detector row CT angiography (CTA) can replace digital subtraction angiography (DSA) to assess the feasibility of endovascular treatment (EVT) in the acute phase after aneurysmal subarachnoid hemorrhage...
  12. doi request reprint Robust CTA lumen segmentation of the atherosclerotic carotid artery bifurcation in a large patient population
    Rashindra Manniesing
    Biomedical Imaging Group Rotterdam, Departments of Medical Informatics and Radiology, Erasmus MC, Rotterdam, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    Med Image Anal 14:759-69. 2010
    ..87% and for the intra-observer set 94% vs. 94%). Therefore the method has potential to replace the manual procedure of lumen segmentation of the atherosclerotic bifurcation in CTA...
  13. doi request reprint Intracranial carotid artery atherosclerosis and the risk of stroke in whites: the Rotterdam Study
    Daniel Bos
    Department of Radiology, Erasmus Medical Center, Rotterdam, the Netherlands2Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    JAMA Neurol 71:405-11. 2014
    ..Intracranial atherosclerosis represents a relatively unexplored, but potentially important, cause of stroke in a white population...
  14. doi request reprint Vascular risk factors, apolipoprotein E, and hippocampal decline on magnetic resonance imaging over a 10-year follow-up
    Tom den Heijer
    Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands
    Alzheimers Dement 8:417-25. 2012
    ..We studied potential risk factors for decline of hippocampal volume...
  15. ncbi request reprint In vivo characterization and quantification of atherosclerotic carotid plaque components with multidetector computed tomography and histopathological correlation
    Thomas T de Weert
    Department of Radiology, Erasmus MC, University Medical Center Rotterdam, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Arterioscler Thromb Vasc Biol 26:2366-72. 2006
    ..Now we evaluated the use of MDCT in vivo to characterize and quantify atherosclerotic carotid plaque components compared with histology as reference standard...
  16. doi request reprint Intracranial carotid artery atherosclerosis: prevalence and risk factors in the general population
    Daniel Bos
    Department of Radiology, Erasmus MC, PO Box 2040, 3000CA Rotterdam, The Netherlands
    Stroke 43:1878-84. 2012
    ..In this study, we determined the prevalence and investigated risk factors of intracranial internal carotid artery calcification (ICAC) as a marker of intracranial atherosclerosis...
  17. doi request reprint Automated brain structure segmentation based on atlas registration and appearance models
    Fedde van der Lijn
    Departments of Medical Informatics and Radiology, Erasmus MC, 3000 CA Rotterdam, The Netherlands
    IEEE Trans Med Imaging 31:276-86. 2012
    ..95 for the cerebellum, and 0.87 for the hippocampus. This was comparable to or better than the other methods, whereas the proposed technique is more widely applicable and robust...
  18. doi request reprint Intracranial aneurysm segmentation in 3D CT angiography: method and quantitative validation with and without prior noise filtering
    Azadeh Firouzian
    Department of Medical Informatics, Erasmus MC, University Medical Centre Rotterdam, The Netherlands
    Eur J Radiol 79:299-304. 2011
    ..Smoothing by nonlinear diffusion with appropriate parameter settings prior to segmentation, slightly improves segmentation accuracy...
  19. ncbi request reprint A semi-automatic method for segmentation of the carotid bifurcation and bifurcation angle quantification on black blood MRA
    Hui Tang
    Department of Radiology, Erasmus MC University Medical Center Rotterdam, The Netherlands
    Med Image Comput Comput Assist Interv 13:97-104. 2010
    ....
  20. doi request reprint Calcification in major vessel beds relates to vascular brain disease
    Daniel Bos
    Department of Radiology, Erasmus MC, Rotterdam, The Netherlands
    Arterioscler Thromb Vasc Biol 31:2331-7. 2011
    ..However, its relationship with cerebrovascular disease has not been investigated extensively. We investigated the relationship between calcification in various vessel beds outside the brain and imaging markers of vascular brain disease...
  21. doi request reprint Accuracy and reproducibility study of automatic MRI brain tissue segmentation methods
    Renske de Boer
    Department of Radiology and Medical Informatics, Erasmus MC, Rotterdam, The Netherlands
    Neuroimage 51:1047-56. 2010
    ..Example sample size calculations demonstrate a rather large effect of the choice of segmentation method on the required number of subjects...
  22. doi request reprint Cerebral microbleeds are related to loss of white matter structural integrity
    Saloua Akoudad
    From the Departments of Epidemiology S A, M D G, A H, M A I, M W V, Radiology S A, M D G, A v d L, W J N, M A I, M W V, Neurology S A, P J K, M A I, and Medical Informatics M d G, W J N, Erasmus MC, University Medical Center Rotterdam and Imaging Science and Technology W J N, Faculty of Applied Sciences, Delft University of Technology, The Netherlands
    Neurology 81:1930-7. 2013
    ..To investigate whether the presence of cerebral microbleeds, which present as focal lesions on imaging, is associated with a diffuse loss of white matter microstructural integrity in the brain...
  23. doi request reprint Genetic loci for coronary calcification and serum lipids relate to aortic and carotid calcification
    Daniel Bos
    Departments of Radiology, Erasmus MC, Rotterdam, The Netherlands
    Circ Cardiovasc Genet 6:47-53. 2013
    ..Hence, for the current study genetic loci for coronary artery calcification and serum lipid levels, one of the strongest risk factors for atherosclerosis, were used to assess their relation with atherosclerosis in different vessel beds...
  24. doi request reprint Changes in normal-appearing white matter precede development of white matter lesions
    Marius de Groot
    Department of Radiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Stroke 44:1037-42. 2013
    ..We therefore investigated whether development of WML is preceded by quantifiable changes in normal-appearing white matter (NAWM)...
  25. doi request reprint Rating method for dilated Virchow-Robin spaces on magnetic resonance imaging
    Hieab H H Adams
    Department of Epidemiology, Erasmus MC, Dr Molewaterplein 50, 3015GE Rotterdam, The Netherlands
    Stroke 44:1732-5. 2013
    ..Dilated Virchow-Robin spaces are an emerging neuroimaging biomarker, but their assessment on MRI needs standardization...
  26. doi request reprint Is a fetal origin of the posterior cerebral artery a risk factor for TIA or ischemic stroke? A study with 16-multidetector-row CT angiography
    Cecile de Monye
    Department of Radiology, Erasmus MC, University Medical Center, s Gravendijkwal 230, Rotterdam, The Netherlands
    J Neurol 255:239-45. 2008
    ..This study assessed the frequency of a fetal origin of the PCA in patients with a TIA or infarct in the territory of the PCA with 16-multidetector-row CT angiography (CTA)...
  27. ncbi request reprint Evaluation of an improved technique for lumen path definition and lumen segmentation of atherosclerotic vessels in CT angiography
    Evert F S van Velsen
    Department of Radiology, Biomedical Imaging Group Rotterdam, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Eur Radiol 17:1738-45. 2007
    ..92). The evaluation shows that the improved definition of a lumen path requires minimal user interaction, and that using this path as initialization leads to good automatic lumen segmentation results...
  28. doi request reprint Statistical analysis of minimum cost path based structural brain connectivity
    Renske de Boer
    Biomedical Imaging Group Rotterdam, Department of Radiology, Erasmus MC, Rotterdam, The Netherlands
    Neuroimage 55:557-65. 2011
    ....
  29. ncbi request reprint Iterative co-linearity filtering and parameterization of fiber tracts in the entire cingulum
    Marius de Groot
    Biomedical Imaging Group Rotterdam, Department of Radiology, Erasmus MC, Rotterdam, The Netherlands
    Med Image Comput Comput Assist Interv 12:853-60. 2009
    ..Our asymmetry analysis shows a higher fractional anisotropy in the left anterior part of the cingulum compared to the right side, and the opposite effect in the posterior part...
  30. doi request reprint Carotid Atherosclerotic Plaque Characteristics on Magnetic Resonance Imaging Relate With History of Stroke and Coronary Heart Disease
    Mariana Selwaness
    From the Departments of Epidemiology M S, D B, Q v d B, M L P P, M A I, A H, O H F, M W V, Radiology D B, Q v d B, M A I, A v d L, M W V, and Neurology M A I, Erasmus MC, Rotterdam, the Netherlands and Department of Cardiology, Biomedical Engineering, Erasmus MC, Rotterdam, The Netherlands J J W
    Stroke 47:1542-7. 2016
    ..We examined whether carotid atherosclerotic wall thickness, stenosis, and plaque composition are related to history of ischemic stroke and coronary heart disease (CHD)...
  31. doi request reprint Arterial stiffness is associated with carotid intraplaque hemorrhage in the general population: the Rotterdam study
    Mariana Selwaness
    From the Departments of Epidemiology M S, G C V, A H, O H F, J C M W, M W V, Radiology Q v d B, A v d L, M W V, Internal Medicine F U S M R, and Cardiology, Biomedical Engineering J J W, Erasmus MC, Rotterdam, The Netherlands
    Arterioscler Thromb Vasc Biol 34:927-32. 2014
    ..In a population-based study, we investigated the association between arterial stiffness and the presence and composition of carotid atherosclerotic plaques...
  32. doi request reprint Joint intensity-and-point based registration of free-hand B-mode ultrasound and MRI of the carotid artery
    Diego D B Carvalho
    Department of Radiology and Department of Medical Informatics, Biomedical Imaging Group Rotterdam, Erasmus MC, Rotterdam 3015 CE, The Netherlands
    Med Phys 41:052904. 2014
    ..To introduce a semiautomatic algorithm to perform the registration of free-hand B-Mode ultrasound (US) and magnetic resonance imaging (MRI) of the carotid artery...
  33. doi request reprint Association between carotid artery plaque ulceration and plaque composition evaluated with multidetector CT angiography
    Philip J Homburg
    Department of Radiology, Erasmus MC, University Medical Center Rotterdam, 3015 CE Rotterdam, The Netherlands
    Stroke 42:367-72. 2011
    ..We evaluated the associations between carotid artery plaque ulceration and plaque characteristics in ischemic stroke patients with ≥50% stenosis, as well as in those with a low degree of stenosis (0% to 49%)...
  34. doi request reprint A 10-year follow-up of hippocampal volume on magnetic resonance imaging in early dementia and cognitive decline
    Tom den Heijer
    Department of Neurology, Erasmus MC, Rotterdam, The Netherlands
    Brain 133:1163-72. 2010
    ....
  35. doi request reprint MRI-based quantification of outflow boundary conditions for computational fluid dynamics of stenosed human carotid arteries
    Harald C Groen
    Biomechanics Laboratory, Biomedical Engineering, Ee2322, Erasmus MC, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    J Biomech 43:2332-8. 2010
    ..If patient-specific flow measurements of the carotid bifurcation are unavailable, estimation of the outflow ratio by the presented empirical relation will result in a good approximation of calculated WSS using CFD...
  36. doi request reprint White matter lesion extension to automatic brain tissue segmentation on MRI
    Renske de Boer
    Biomedical Imaging Group Rotterdam, Departments of Radiology and Medical Informatics, Erasmus MC, Rotterdam, The Netherlands
    Neuroimage 45:1151-61. 2009
    ..The results indicated that the automatic segmentation accuracy is close to the interobserver variability of manual segmentations...
  37. doi request reprint Prevalence and calcification of intracranial arterial stenotic lesions as assessed with multidetector computed tomography angiography
    Philip J Homburg
    Department of Radiology, Erasmus MC, University Medical Center Rotterdam, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    Stroke 42:1244-50. 2011
    ..We evaluated the prevalence, distribution, calcification, and the risk factors predisposing ICAS in a European stroke population...
  38. doi request reprint Genetic loci for serum lipid fractions and intracerebral hemorrhage
    Saloua Akoudad
    Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, The Netherlands Department of Radiology, Erasmus MC, University Medical Center Rotterdam, The Netherlands Department of Neurology, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Atherosclerosis 246:287-92. 2016
    ..To ascertain whether there is a genetic basis for this inverse association, we studied established genetic loci for serum total, LDL, and HDL cholesterol, and triglycerides in their association with ICH and microbleeds...
  39. doi request reprint TMEM106B influences volume of left-sided temporal lobe and interhemispheric structures in the general population
    Hieab H H Adams
    Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands Department of Radiology, Erasmus MC, Rotterdam, The Netherlands
    Biol Psychiatry 76:503-8. 2014
    ..The TMEM106B rs1990622 polymorphism is associated with frontotemporal lobar degeneration, but little is known about how it affects the brain...
  40. ncbi request reprint Carotid artery lumen segmentation in 3D free-hand ultrasound images using surface graph cuts
    Andrés M Arias Lorza
    Department of Radiology, Erasmus MC, The Netherlands
    Med Image Comput Comput Assist Interv 16:542-9. 2013
    ..Our method successfully segmented the lumen in all cases. We obtained an average dice overlap with respect to a manual segmentation of 84% for healthy volunteers. For the patient data, we obtained a dice overlap of 66.7%...
  41. doi request reprint Cerebral microbleeds and the risk of mortality in the general population
    Saloua Akoudad
    Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Office secretariat Epidemiology Na 28 18, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Eur J Epidemiol 28:815-21. 2013
    ..Our data suggest that microbleeds may mark severe underlying vascular pathology associated with poorer survival. ..
  42. ncbi request reprint Optimization of CT angiography of the carotid artery with a 16-MDCT scanner: craniocaudal scan direction reduces contrast material-related perivenous artifacts
    Cecile de Monye
    Department of Radiology, Erasmus University Medical Center, Dr Molewaterplein 40, Rotterdam, The Netherlands, 3015 GD
    AJR Am J Roentgenol 186:1737-45. 2006
    ..The objective of our study was to compare the effect of a caudocranial scan direction versus a craniocaudal scan direction on arterial enhancement and perivenous artifacts in 16-MDCT angiography of the supraaortic arteries...
  43. doi request reprint Cortical and cerebellar activation induced by reflexive and voluntary saccades
    Caroline K L Schraa-Tam
    Department of Radiology, Erasmus MC, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Exp Brain Res 192:175-87. 2009
    ..Our results suggest that the alleged separate mechanisms for saccadic control of reflexive and self-paced voluntary are mainly observed in cerebral rather than cerebellar areas...
  44. ncbi request reprint Sixteen-detector row CT angiography of carotid arteries: comparison of different volumes of contrast material with and without a bolus chaser
    Cecile de Monye
    Department of Radiology, Erasmus Medical Center, 3015 GD Rotterdam, The Netherlands
    Radiology 237:555-62. 2005
    ..To prospectively compare different volumes of intravenously administered contrast material with and without a bolus chaser at 16-detector row computed tomographic (CT) angiography of the carotid arteries...
  45. doi request reprint Atherosclerotic plaque surface morphology in the carotid bifurcation assessed with multidetector computed tomography angiography
    Thomas T de Weert
    Department of Radiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Stroke 40:1334-40. 2009
    ..We analyzed the frequency and location of plaque irregularities in a large cohort of patients with ischemic cerebrovascular disease and the relation with severity of stenosis, cardiovascular risk factors, and symptomatology...
  46. ncbi request reprint Intravenous contrast material administration at helical 16-detector row CT coronary angiography: effect of iodine concentration on vascular attenuation
    Filippo Cademartiri
    Department of Radiology, Erasmus Medical Center, Dr Molewaterplein 40, 3015GD Rotterdam, The Netherlands
    Radiology 236:661-5. 2005
    ..The same pattern was observed in the coronary arteries. Contrast materials with higher iodine concentrations yield significantly higher attenuation in the descending aorta and coronary arteries...
  47. pmc Structural and functional brain abnormalities place phenocopy frontotemporal dementia (FTD) in the FTD spectrum
    Rebecca M E Steketee
    Department of Radiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Neuroimage Clin 11:595-605. 2016
    ..We aimed to identify abnormalities in gray matter (GM) volume and perfusion in phFTD and to assess whether phFTD belongs to the FTD spectrum. We compared phFTD patients with both healthy controls and bvFTD patients...
  48. doi request reprint Comparison of Atherosclerotic Calcification in Major Vessel Beds on the Risk of All-Cause and Cause-Specific Mortality: The Rotterdam Study
    Daniel Bos
    From the Departments of Radiology D B, A L, M W V, M A I, Epidemiology D B, M J G L, M K, A H, O H F, M W V, M A I, Cardiology M J G L, and Neurology M A I, Erasmus MC, Rotterdam, The Netherlands
    Circ Cardiovasc Imaging 8:. 2015
    ..Atherosclerosis is a major contributor to global morbidity and mortality. Although atherosclerosis is a systemic disease, its burden varies considerably across vessel beds, which may translate into differences in mortality risk...
  49. doi request reprint Concurrent white and gray matter degeneration of disease-specific networks in early-stage Alzheimer's disease and behavioral variant frontotemporal dementia
    Rebecca M E Steketee
    Department of Radiology, Erasmus MC University Medical Centre Rotterdam, Rotterdam, The Netherlands
    Neurobiol Aging 43:119-28. 2016
    ..This indicates concurrent degeneration in disease-specific networks. Our methodology allows for the detection of incipient abnormalities that go undetected in conventional between-group analyses. ..
  50. pmc Early-stage differentiation between presenile Alzheimer's disease and frontotemporal dementia using arterial spin labeling MRI
    Rebecca M E Steketee
    Department of Radiology, Erasmus MC University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Eur Radiol 26:244-53. 2016
    ....
  51. doi request reprint Coexistence of Calcification, Intraplaque Hemorrhage and Lipid Core within the Asymptomatic Atherosclerotic Carotid Plaque: The Rotterdam Study
    Quirijn J A van den Bouwhuijsen
    Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands
    Cerebrovasc Dis 39:319-24. 2015
    ..Therefore, in this study we set out to investigate the coexistence of intraplaque calcification, hemorrhage and lipid core within the carotid artery using a multi-modality imaging approach...
  52. doi request reprint Epicardial fat volume is related to atherosclerotic calcification in multiple vessel beds
    Daniel Bos
    Department of Radiology, Erasmus MC, PO Box 2040, Rotterdam 3000CA, The Netherlands Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands
    Eur Heart J Cardiovasc Imaging 16:1264-9. 2015
    ..To investigate relationships between epicardial fat volume and atherosclerosis in multiple major vessel beds...
  53. doi request reprint Tract-specific white matter degeneration in aging: the Rotterdam Study
    Marius de Groot
    Department of Radiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands Department of Medical Informatics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Alzheimers Dement 11:321-30. 2015
    ..Loss of brain white matter microstructure is presumed to be an early sign of neurodegenerative disease. Yet, little is known on microstructural changes of various white matter tracts with normal aging...
  54. doi request reprint Differences between smooth pursuit and optokinetic eye movements using limited lifetime dot stimulation: a functional magnetic resonance imaging study
    Caroline K L Schraa-Tam
    Department of Radiology, Erasmus MC, Rotterdam, The Netherlands
    Clin Physiol Funct Imaging 29:245-54. 2009
    ..These results showed that the smooth pursuit and optokinetic eye movement systems can be differentiated with fMRI using limited lifetime dots as an effective OKR stimulus...
  55. doi request reprint Suspected carotid artery stenosis: cost-effectiveness of CT angiography in work-up of patients with recent TIA or minor ischemic stroke
    Aletta T R Tholen
    Department of Radiology, Erasmus University Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Radiology 256:585-97. 2010
    ..To assess the effectiveness and cost-effectiveness of state-of-the-art noninvasive diagnostic imaging strategies in patients with a transient ischemic attack (TIA) or minor stroke who are suspected of having carotid artery stenosis (CAS)...
  56. doi request reprint Segmentation of the outer vessel wall of the common carotid artery in CTA
    Danijela Vukadinovic
    Biomedical Imaging Group Rotterdam, Department of Radiology, Erasmus MC, 3015GE Rotterdam, The Netherlands
    IEEE Trans Med Imaging 29:65-76. 2010
    ..The method has been validated on a dataset of 60 CTA images. The experimental results show that the accuracy of the method is comparable to the interobserver variability...
  57. doi request reprint Atherosclerotic plaque ulceration in the symptomatic internal carotid artery is associated with nonlacunar ischemic stroke
    Philip J Homburg
    Department of Radiology, Erasmus MC, University Medical Center Rotterdam, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    Stroke 41:1151-6. 2010
    ..It can be accurately detected with multidetector CTA. We hypothesized that atherosclerotic plaque ulceration is associated with nonlacunar ischemic stroke rather than lacunar stroke...
  58. doi request reprint Fine-mapping the effects of Alzheimer's disease risk loci on brain morphology
    Gennady V Roshchupkin
    Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands Department of Medical Informatics, Erasmus MC, Rotterdam, The Netherlands
    Neurobiol Aging 48:204-211. 2016
    ..nl/ADSNPs/. In this single largest imaging genetics data set worldwide, we found that AD risk loci affect cortical gray matter in several brain regions known to be involved in AD, as well as regions that have not been implicated before...
  59. doi request reprint Association of Cerebral Microbleeds With Cognitive Decline and Dementia
    Saloua Akoudad
    Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands2Department of Radiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands3Department of Neurology, Erasmus MC, University Me
    JAMA Neurol 73:934-43. 2016
    ..To date, whether their presence is associated with cognitive deterioration in the general population remains unclear...
  60. doi request reprint Atherosclerotic calcification is related to a higher risk of dementia and cognitive decline
    Daniel Bos
    Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Alzheimers Dement 11:639-47.e1. 2015
    ..Longitudinal data on the role of atherosclerosis in different vessel beds in the etiology of cognitive impairment and dementia are scarce and inconsistent...
  61. doi request reprint Altered tract-specific white matter microstructure is related to poorer cognitive performance: The Rotterdam Study
    Lotte G M Cremers
    Department of Radiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Neurobiol Aging 39:108-17. 2016
    ..Tract-specific microstructural changes may aid in better understanding the mechanism of cognitive impairment and neurodegenerative diseases. ..
  62. doi request reprint Atherosclerotic plaque in the left carotid artery is more vulnerable than in the right
    Mariana Selwaness
    From the Departments of Epidemiology M S, Q v d B, R S v O, A H, O H F, M V, Radiology Q v d B, A v d L, M V, and Cardiology J J W, Erasmus MC, Rotterdam, The Netherlands
    Stroke 45:3226-30. 2014
    ..It is unknown whether this asymmetrical prevalence relates to differences in carotid atherosclerosis. We compared atherosclerotic plaque prevalence, severity, and composition between left and right carotid arteries...
  63. doi request reprint Cerebral Microbleeds Are Associated With an Increased Risk of Stroke: The Rotterdam Study
    Saloua Akoudad
    From Departments of Epidemiology S A, M L P P, A H, M A I, M W V, Radiology S A, A v d L, M A I, M W V, and Neurology S A, M L P P, P J K, M A I, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Circulation 132:509-16. 2015
    ..Microbleeds are also frequently found in healthy elderly, a population in which the clinical implication of microbleeds is unknown...
  64. doi request reprint Semi-automatic MRI segmentation and volume quantification of intra-plaque hemorrhage
    Hui Tang
    Biomedical Imaging Group Rotterdam, Department of Medical Informatics, Erasmus MC, P O Box 2040, 3000 CA, Rotterdam, The Netherlands
    Int J Comput Assist Radiol Surg 10:67-74. 2015
    ..The aim of our work was to develop and evaluate a method for semi-automatic IPH segmentation in T1-weighted (T1w)-magnetic resonance imaging (MRI)...
  65. pmc Cerebral microbleeds are associated with the progression of ischemic vascular lesions
    Saloua Akoudad
    Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    Cerebrovasc Dis 37:382-8. 2014
    ..We therefore aimed to investigate whether pre-existing and incident cerebral microbleeds (CMBs) are related to the progression of ischemic lesions in the general population...
  66. ncbi request reprint Carotid plaque composition and cerebral infarction: MR imaging study
    Mohamed Ouhlous
    Department of Radiology, Erasmus MC, Rotterdam, The Netherlands
    AJNR Am J Neuroradiol 26:1044-9. 2005
    ..We analyzed the relationship between the composition of the atherosclerotic plaque at the carotid artery bifurcation and ipsilateral ischemic cerebral lesions on MR imaging...
  67. doi request reprint Automated measurement of local white matter lesion volume
    Fedde van der Lijn
    Department of Medical Informatics, Erasmus MC, Rotterdam, The Netherlands
    Neuroimage 59:3901-8. 2012
    ..But the proposed method can localize the region of association with greater precision than techniques that distinguish between periventricular and subcortical lesions only...
  68. doi request reprint Estimating 3D lumen centerlines of carotid arteries in free-hand acquisition ultrasound
    Diego D B Carvalho
    Department of Radiology and Med Informatics, Biomedical Imaging Group Rotterdam, Erasmus MC, Rotterdam, The Netherlands
    Int J Comput Assist Radiol Surg 7:207-15. 2012
    ..Challenging aspects here are speckle noise in US images, artifacts, and the lack of contrast in the direction orthogonal to the US beam direction...
  69. ncbi request reprint Histogram-based selective deblurring to improve computed tomography imaging of calcifications
    Empar Rollano-Hijarrubia
    Department of Radiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
    Invest Radiol 42:8-22. 2007
    ..This study aims to deconvolve calcifications in the transverse and longitudinal directions while avoiding noise amplification and edge-ringing artifacts in the surrounding low-density structures...
  70. ncbi request reprint Kidney function is related to cerebral small vessel disease
    M Arfan Ikram
    Department of Epidemiology and Biostatistics, Erasmus MC, P O Box 2040, 3000 CA, Rotterdam, The Netherlands
    Stroke 39:55-61. 2008
    ..We investigated this association in a population-based study of elderly persons...
  71. doi request reprint Incidence of cerebral microbleeds in the general population: the Rotterdam Scan Study
    Mariëlle M F Poels
    Department of Radiology, Erasmus MC, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Stroke 42:656-61. 2011
    ..Cerebral microbleeds are frequently seen in the general elderly population, but it is unknown at what rate they occur with aging and whether once present can disappear over time...
  72. pmc Atherosclerotic plaque component segmentation in combined carotid MRI and CTA data incorporating class label uncertainty
    Arna van Engelen
    Biomedical Imaging Group Rotterdam, Departments of Medical Informatics and Radiology, Erasmus MC, Rotterdam, The Netherlands
    PLoS ONE 9:e94840. 2014
    ....
  73. ncbi request reprint In vitro characterization of atherosclerotic carotid plaque with multidetector computed tomography and histopathological correlation
    Thomas T de Weert
    Department of Radiology, Erasmus MC, Dr Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands
    Eur Radiol 15:1906-14. 2005
    ..83 and R2=0.68, respectively). The mean difference in lipid area was 0.1 mm2 (95% CI=-2.1-2.3 mm2). This in vitro study showed that MDCT is capable of characterizing and quantifying the lipid rich portion of the atherosclerotic plaque...
  74. ncbi request reprint Sixteen-row multislice computed tomography: basic concepts, protocols, and enhanced clinical applications
    Filippo Cademartiri
    Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Semin Ultrasound CT MR 25:2-16. 2004
    ..The technical foundations of spiral CT imaging and the main scan and reconstruction parameters are described in this article. Updated protocols and clinical examples of the latest applications are also discussed...
  75. ncbi request reprint MDCT detection of fibromuscular dysplasia of the internal carotid artery
    Cecile de Monye
    Department of Radiology, Erasmus University Medical Center, Dr Molewaterplein 40, Rotterdam 3015 GD, The Netherlands
    AJR Am J Roentgenol 188:W367-9. 2007
    ..If patients with cerebrovascular symptoms undergo screening with CT angiography of the supraaortic vessels, more cases of fibromuscular dysplasia will be recognized as a cause of neurologic symptoms...
  76. ncbi request reprint Quadrature coil design for high-resolution carotid artery imaging scores better than a dual phased-array coil design with the same volume coverage
    Mohamed Ouhlous
    Department of Radiology, Erasmus MC, University Medical Center, Erasmus Medical Centre, 3015 GD Rotterdam, The Netherlands
    J Magn Reson Imaging 25:1079-84. 2007
    ..To evaluate the ability of a custom-built coil design to provide improved signal-to-noise ratio (SNR) and less signal drop with increasing depth at the carotid artery...
  77. doi request reprint Postconcussion syndrome after minor head injury: brain activation of working memory and attention
    Marion Smits
    Department of Radiology, Erasmus MC University Medical Centre Rotterdam, Rotterdam, The Netherlands
    Hum Brain Mapp 30:2789-803. 2009
    ....
  78. doi request reprint Automated bone removal in CT angiography: comparison of methods based on single energy and dual energy scans
    Marcel van Straten
    Department of Radiology, Erasmus MC University Medical Center, CA Rotterdam, The Netherlands
    Med Phys 38:6128-37. 2011
    ..To evaluate dual energy based methods for bone removal in computed tomography angiography (CTA) images and compare these with single energy based methods that use an additional, nonenhanced, CT scan...
  79. doi request reprint Long-term changes in cerebellar activation during functional recovery from transient peripheral motor paralysis
    Albertine Smit
    Department of Neuroscience, Erasmus MC, Rotterdam, The Netherlands
    Exp Neurol 226:33-9. 2010
    ....
  80. ncbi request reprint Non-invasive 16-row multislice CT coronary angiography: usefulness of saline chaser
    Filippo Cademartiri
    Department of Radiology, Erasmus Medical Center, Dr Molenwaterplein 40, 3015 Rotterdam, The Netherlands
    Eur Radiol 14:178-83. 2004
    ..05), for groups 1 and 2, respectively. One hundred milliliters of CM with 40 ml of saline chaser provides the same attenuation as 140 ml of CM (35% less) with decreased hyper-attenuation in the superior vena cava...
  81. ncbi request reprint Diffusion-weighted imaging to compare different cerebral protection devices in carotid artery stenting
    Zwenneke H Flach
    Department of Radiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    EuroIntervention 3:243-8. 2007
    ....
  82. doi request reprint Remedial action and feedback processing in a time-estimation task: evidence for a role of the rostral cingulate zone in behavioral adjustments without learning
    Frederik M van der Veen
    Department of Psychiatry, Erasmus MC, Rotterdam, The Netherlands
    Neuroimage 54:447-54. 2011
    ..Both findings can be explained in terms of the RCZ being involved in facilitating remedial action as opposed to the suggested signaling function (outcome is worse than expected) proposed by the reinforcement learning theory...
  83. ncbi request reprint [Evaluation of newer risk markers for coronary heart disease: the Rotterdam Study]
    Maarten J G Leening
    afd Epidemiologie, Erasmus MC, Rotterdam, The Netherlands
    Ned Tijdschr Geneeskd 157:A6123. 2013
    ..Prospective cohort study in the general population of Rotterdam, the Netherlands (The Rotterdam Study)...
  84. ncbi request reprint Noninvasive detection of a ruptured aneurysm at a basilar artery fenestration with submillimeter multisection CT angiography
    Filippo Cademartiri
    Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands
    AJNR Am J Neuroradiol 24:2009-10. 2003
    ..The diagnosis was assessed with 16-row multisection CT angiography and was confirmed by using digital subtraction angiography. The patient was successfully treated with coil placement...
  85. ncbi request reprint Cerebral ischemia after carotid intervention
    H Zwenneke Flach
    Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands
    J Endovasc Ther 11:251-7. 2004
    ..To determine the incidence of symptomatic and asymptomatic cerebral ischemic lesions found on diffusion-weighted magnetic resonance imaging (DW-MRI) after carotid interventions...
  86. doi request reprint Advanced magnetic resonance neuroimaging of language function recovery after aphasic stroke: a technical review
    Marion Smits
    Department of Radiology, Erasmus MC University Medical Centre Rotterdam, Rotterdam, The Netherlands
    Arch Phys Med Rehabil 93:S4-14. 2012
    ..The purpose of this article is to discuss the methodologic challenges of fMRI and DTI in the assessment of language recovery after aphasic stroke...
  87. ncbi request reprint Evaluation of a dedicated dual phased-array surface coil using a black-blood FSE sequence for high resolution MRI of the carotid vessel wall
    Mohamed Ouhlous
    Department of Radiology, University Hospital Rotterdam, Rotterdam, The Netherlands
    J Magn Reson Imaging 15:344-51. 2002
    ..To investigate the ability of magnetic resonance imaging (MRI) to visualize the carotid vessel wall using a phased-array coil and a black-blood (BB) fast spin-echo (FSE) sequence...
  88. doi request reprint Withdrawal of statins and risk of subarachnoid hemorrhage
    Roelof Risselada
    Department of Medical Informatics, Erasmus MC, room Ee 2159, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    Stroke 40:2887-92. 2009
    ..Vascular endothelium, which can be affected by statins, is believed to play a substantial role in subarachnoid hemorrhage (SAH). Our objective was to estimate the association between use and withdrawal of statins and the risk of SAH...
  89. pmc Frequency of ubiquitin and FUS-positive, TDP-43-negative frontotemporal lobar degeneration
    Harro Seelaar
    Department of Neurology, Erasmus MC, University Medical Center Rotterdam, Room Hs 611, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    J Neurol 257:747-53. 2010
    ..The existence of this pathological subtype can be predicted with reasonable certainty by age at onset <or=40 years, negative family history, bvFTD and caudate atrophy on MRI...
  90. ncbi request reprint Plaque rupture in the carotid artery is localized at the high shear stress region: a case report
    Harald C Groen
    Biomedical Engineering, Biomechanics Laboratory, Erasmus MC, CA Rotterdam, The Netherlands
    Stroke 38:2379-81. 2007
    ..Our data suggest that high WSS influences plaque vulnerability and therefore may become a potential parameter for predicting future events...
  91. doi request reprint Inadequate acoustical temporal bone window in patients with a transient ischemic attack or minor stroke: role of skull thickness and bone density
    Annemarie D Wijnhoud
    Department of Neurology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    Ultrasound Med Biol 34:923-9. 2008
    ..This may help to select patients with ischemic stroke for diagnostic TCD screening and to facilitate targeted delivery of ultrasound-enhanced thrombolysis...
  92. doi request reprint fMRI of optokinetic eye movements with and without a contribution of smooth pursuit
    Caroline K L Schraa-Tam
    Department of Radiology, Erasmus MC, Rotterdam, The Netherlands
    J Neuroimaging 18:158-67. 2008
    ..A moving pattern of limited-lifetime-dot stimulation does not target the smooth pursuit eye movement system...
  93. ncbi request reprint Brain tissue volumes in the general elderly population. The Rotterdam Scan Study
    M Arfan Ikram
    Department of Epidemiology and Biostatistics, Erasmus MC, Dr Molewaterplein 50, 3015 GE Rotterdam, The Netherlands
    Neurobiol Aging 29:882-90. 2008
    ..In the elderly, higher age, small vessel disease and cardiovascular risk factors are associated with smaller brain volume, especially WM volume...
  94. ncbi request reprint Functional MR imaging of language processing: an overview of easy-to-implement paradigms for patient care and clinical research
    Marion Smits
    Department of Radiology, Erasmus MC University Medical Center Rotterdam, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Radiographics 26:S145-58. 2006
    ....
  95. ncbi request reprint An fMRI study on smooth pursuit and fixation suppression of the optokinetic reflex using similar visual stimulation
    Caroline K L Schraa-Tam
    Department of Radiology, Erasmus MC, Rotterdam, The Netherlands
    Exp Brain Res 185:535-44. 2008
    ..The increased activity in the oculomotor areas of the cerebellum during smooth pursuit is probably due to the presence of an active eye movement component...
  96. ncbi request reprint Parameters affecting bolus geometry in CTA: a review
    Filippo Cademartiri
    Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands
    J Comput Assist Tomogr 26:598-607. 2002
    ..Important parameters of bolus geometry and methods of bolus timing (test bolus and bolus tracking) are described. Recommendations are given for an optimal CTA protocol...