Inge Marie Obdeijn
Affiliation: Erasmus MC
Country: The Netherlands
- Should we screen BRCA1 mutation carriers only with MRI? A multicenter studyInge Marie Obdeijn
Department of Radiology, Erasmus University Medical Center Rotterdam, Groene Hilledijk 301, 3075, EA, Rotterdam, The Netherlands
Breast Cancer Res Treat 144:577-82. 2014..Given the potential risk of radiation-induced breast cancer in young mutation carriers, we propose to screen BRCA1 mutation carriers yearly with MRI from age 25 onwards and to start with mammographic screening not earlier than age 40...
- Preoperative breast MRI can reduce the rate of tumor-positive resection margins and reoperations in patients undergoing breast-conserving surgeryInge Marie Obdeijn
Department of Radiology, Erasmus MC Rotterdam, Groene Hilledijk 301, 3075 EA Rotterdam, The Netherlands
AJR Am J Roentgenol 200:304-10. 2013..In breast cancer patients eligible for breast-conserving surgery, we evaluated whether the information provided by preoperative MRI of the breast would result in fewer tumor-positive resection margins and fewer reoperations...
- Breast density as indicator for the use of mammography or MRI to screen women with familial risk for breast cancer (FaMRIsc): a multicentre randomized controlled trialSepideh Saadatmand
Department of Surgery, Erasmus University Medical Centre, Rotterdam, Netherlands
BMC Cancer 12:440. 2012..The aim of the Familial MRI Screening Study (FaMRIsc) is to compare the efficacy of MRI screening to mammography for women with a familial risk. Furthermore, we will assess the influence of breast density...
- BRCA1-associated breast cancers present differently from BRCA2-associated and familial cases: long-term follow-up of the Dutch MRISC Screening StudyAdriana J Rijnsburger
Erasmus MC, Daniel den Hoed Cancer Center, Groene Hilledijk 301, 3075 EA, Rotterdam, The Netherlands
J Clin Oncol 28:5265-73. 2010..The Dutch MRI Screening Study on early detection of hereditary breast cancer started in 1999. We evaluated the long-term results including separate analyses of BRCA1 and BRCA2 mutation carriers and first results on survival...
- Hereditary breast cancer growth rates and its impact on screening policyMadeleine M A Tilanus-Linthorst
Department of Surgical Oncology, Erasmus University Medical Centre, Rotterdam, The Netherlands
Eur J Cancer 41:1610-7. 2005..It is recommended that the screening frequency should be adjusted according to a woman's age and a high-sensitive biannual test may be appropriate before the age of 40 years...
- Factors affecting sensitivity and specificity of screening mammography and MRI in women with an inherited risk for breast cancerMieke Kriege
Family Cancer Clinic, Department of Medical Oncology, Erasmus MC Daniel den Hoed Cancer Center, Groene Hilledijk 301, 3075 EA Rotterdam, The Netherlands
Breast Cancer Res Treat 100:109-19. 2006..In the current subsequent study we investigated whether these results are influenced by age, a BRCA1/2 mutation, menopausal status and breast density...
- A BRCA1/2 mutation, high breast density and prominent pushing margins of a tumor independently contribute to a frequent false-negative mammographyMadeleine Tilanus-Linthorst
Department of Surgery, Erasmus University Medical Center Rotterdam, The Netherlands
Int J Cancer 102:91-5. 2002..Pushing margins of the tumor partly explain these results. For early BC detection in mutation carriers additional methods like MRI may be needed. This may not be necessary in other young women with breast symptoms...
- BRCA1 mutation and young age predict fast breast cancer growth in the Dutch, United Kingdom, and Canadian magnetic resonance imaging screening trialsMadeleine M A Tilanus-Linthorst
Department of Surgery, Erasmus University Medical Centre, Rotterdam, The Netherlands
Clin Cancer Res 13:7357-62. 2007..We investigated the effect of a BRCA1 or BRCA2 mutation and age on the growth rate of breast cancers, as this may influence the optimal screening frequency...
- Magnetic resonance imaging improves breast screening sensitivity in BRCA mutation carriers age ≥ 50 years: evidence from an individual patient data meta-analysisXuan Anh Phi
Xuan Anh Phi, Edwin R Van den Heuvel, and Geertruida H de Bock, University of Groningen, University Medical Center Groningen, Groningen Inge Marie Obdeijn, Madeleine M A Tilanus Linthorst, and Harry J de Koning, Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands Nehmat Houssami, School of Public Health, Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia Ellen Warner and Rodica Mandel, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario Isabelle Trop, Hospital of Montreal, Montreal, Quebec, Canada Francesco Sardanelli, University of Milan School of Medicine, Istituto Di Ricovero e Cura a Carattere Scientifico Policlinico San Donato, Milan Filippo Santoro, Istituto Superiore di Sanita, Rome, Italy Martin O Leach and Gek Kwan Lim, Institute of Cancer Research and Royal Marsden National Health Service Foundation Trust, London, United Kingdom and Christopher C Riedl and Thomas H Helbich, Medical University Vienna, Vienna, Austria
J Clin Oncol 33:349-56. 2015..Therefore, we investigated the evidence on age-related screening accuracy in women with BRCA1/2 mutations using individual patient data (IPD) meta-analysis...
- Survival benefit in women with BRCA1 mutation or familial risk in the MRI screening study (MRISC)Sepideh Saadatmand
Department of Surgery, Erasmus Medical Center Cancer Institute, Rotterdam, The Netherlands
Int J Cancer 137:1729-38. 2015..064, HR 0.51, CI 0.24-1.06). Annual screening with MRI and mammography improves metastasis free survival in women with BRCA1 mutation or familial predisposition. ..
- Efficacy of MRI and mammography for breast-cancer screening in women with a familial or genetic predispositionMieke Kriege
Rotterdam Family Cancer Clinic, Department of Medical Oncology, Erasmus Medical Center Daniel den Hoed Cancer Center, Rotterdam, The Netherlands
N Engl J Med 351:427-37. 2004..We compared the efficacy of magnetic resonance imaging (MRI) with that of mammography for screening in this group of high-risk women...