Affiliation: Erasmus MC Rotterdam
Location: Rotterdam, Netherlands
Vice-Chairman / Vice-Head Residency Training Program
Depts. of Anesthesiology and Emergency medicine
Chairman Medical Incident Committee Erasmus MC
Chairman Dutch Society of Neuroanesthesiology
Editor in Chief Dutch Anesthesia Journal
Fields of interest:
Awake brain surgery
Patient safety and comfort
- The influence of various anesthetics on the release and metabolism of thyroid hormones: results of two clinical studiesU Borner
Department of Anesthesiology, Medical Faculty, University of Cologne, Germany
Anesth Analg 81:612-8. 1995..Hence we assume the increase to be due to hormone release from thyroid and/or extrathyroidal stores--an intercompartmental shifting...
- Reversal of rocuronium-induced (1.2 mg kg-1) profound neuromuscular block by accidental high dose of sugammadex (40 mg kg-1)A L Molina
Department of Anaesthesiology, Erasmus University Medical Centre, Rotterdam, and Martini Hospital Groningen, The Netherlands
Br J Anaesth 98:624-7. 2007..2 mg kg-1) profound neuromuscular block. A fast and efficient recovery from profound neuromuscular block was achieved and no adverse events or other safety concerns were reported...
- Reversal of rocuronium-induced (1.2 mg/kg) profound neuromuscular block by sugammadex: a multicenter, dose-finding and safety studyHans D de Boer
Department of Anesthesiology, Radboud University Medical Center Nijmegen, The Netherlands
Anesthesiology 107:239-44. 2007..This study investigated the efficacy and safety of sugammadex in reversing rocuronium-induced profound neuromuscular blockade at 5 min in American Society of Anesthesiologists physical status I and II patients...
- B and T cell imbalances in CSF of patients with Hu-antibody associated PNSMarieke de Graaf
Department of Medical Oncology, Erasmus University Medical Center, Rotterdam, The Netherlands
J Neuroimmunol 195:164-70. 2008..In addition, the autoimmune hypothesis of Hu-PNS is supported by the relative NKT cell deficiency...
- [Perioperative care for the older patient]E Blommers
Erasmus MC Centrum, afd Anesthesiologie, H 12 Noord, Postbus 2040, 3000 CA Rotterdam
Ned Tijdschr Geneeskd 152:1513-7. 2008..Recent developments focus on multimodal perioperative care of the older patient to shorten hospital stay, using minimal invasive surgery, postoperative anaesthesiology rounds and early geriatric consultation...
- Protocol compliance and time management in blunt trauma resuscitationW R Spanjersberg
Erasmus MC, University Medical Center Rotterdam, Department of Surgery Traumatology, PO Box 2040, 3000 CA Rotterdam, The Netherlands
Emerg Med J 26:23-7. 2009....
- Train-of-four ratio recovery often precedes twitch recovery when neuromuscular block is reversed by sugammadexL M Staals
Department of Anaesthesiology, Erasmus University Medical Centre, Sophia Children s Hospital, Rotterdam, The Netherlands
Acta Anaesthesiol Scand 55:700-7. 2011..9. The recovery time of T1 was not described. This retrospective investigation describes the recovery of T1 vs. TOF ratio after the reversal of NMB with sugammadex...
- Perioperative care of the older patientE Blommers
Department of Anesthesiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
Z Gerontol Geriatr 44:187-91. 2011..Recent developments focus on multimodal perioperative care of the older patient, using minimally invasive surgery, postoperative anesthesiology rounds, and early geriatric consultation...
- A randomised study of perioperative esmolol infusion for haemodynamic stability during major vascular surgery; rationale and design of DECREASE-XIIIE J Bakker
Department of Anesthesiology, Erasmus Medical Centre, Rotterdam, The Netherlands
Eur J Vasc Endovasc Surg 42:317-23. 2011....
- [Physostigmine for the immediate treatment of a patient with the central anticholinergic syndrome induced by cocaine cut with atropine]W P Ridder
Erasmus MC, afd Anesthesiologie, Dr Molewaterplein 40, 3015 GD, Rotterdam
Ned Tijdschr Geneeskd 149:1701-3. 2005..In the presence of indications for such an intoxication, physostigmine is the antidote of first choice...
- Trends but not individual values of central venous oxygen saturation agree with mixed venous oxygen saturation during varying hemodynamic conditionsMichael H Dueck
Department of Anesthesiology, University of Cologne, Cologne, Germany
Anesthesiology 103:249-57. 2005..The inconsistency of study results may result from different study designs and different, partly questionable, statistical approaches...
- A survey of autologous blood transfusion practices in GermanyJ Kaufmann
Department of Anaesthesiology, University of Cologne, Germany
Transfus Med 14:335-41. 2004..The use of PABD did not change significantly, the use of haemodilution declined markedly and the use of peri-operative cell salvage increased markedly during the past 5 years before the survey...
- [Early extubation following intracranial procedures: contra]U Borner
Klinik fur Anasthesiologie und Operative Intensivmedizin, Universitat, Koln
Anasthesiol Intensivmed Notfallmed Schmerzther 33:336-7. 1998
- Does an analysis of exhaled air indicate the metabolic state of critically ill patients?U Borner
Intensive Care Med 24:403-4. 1998
- Efficacy of oral iron supplementation is not enhanced by additional intravenous iron during autologous blood donationS M Kasper
Department of Anesthesiology, University of Cologne, Germany
Transfusion 38:764-70. 1998....
- Postoperative analgesia with no motor block by continuous epidural infusion of ropivacaine 0.1% and sufentanil after total hip replacementS Kampe
Department of Anesthesiology, University of Cologne, Germany
Anesth Analg 89:395-8. 1999..1% in treating pain after hip replacement. We found that ropivacaine 0.1% and sufentanil 1 microgram/mL led to a sixfold reduction in opioid requirements after total hip replacement by producing a negligible motor block...
- Surgery of intrinsic cerebral neoplasms in eloquent areas under local anesthesiaH Ebel
Department of Neurosurgery, University of Cologne, Germany
Minim Invasive Neurosurg 43:192-6. 2000....
- [A cerebral watershed infarction after general anaesthesia in a patient with increased anti-cardiolipin antibody level]S J C Verbrugge
Afdeling Anesthesiologie, Erasmus MC, Rotterdam, Netherlands
Anaesthesist 53:341-6. 2004..Patients with increased anti-cardiolipin antibody levels and who suffer from epileptic attacks have an increased risk of thromboembolic events...
- Awake craniotomy for glioblastoma in a 9-year-old childM Klimek
Department of Anaesthesiology, Erasmus MC, University Medical Centre, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
Anaesthesia 59:607-9. 2004..We believe that it is the individual level of development of the child that determines suitability for this type of surgery...
- A simulation model for determining the optimal size of emergency teams on call in the operating room at nightJeroen M van Oostrum
Department of Operating Rooms, Erasmus University Medical Center, Room NH 4A, P O Box 2040, 3000 CA Rotterdam, The Netherlands
Anesth Analg 107:1655-62. 2008..We developed a process to determine the optimal OR team composition during the night, such that staffing costs are minimized, while providing adequate resources to start surgery within the safety interval...
- Awake craniotomy induces fewer changes in the plasma amino acid profile than craniotomy under general anesthesiaJaap W Hol
Department of Anesthesiology, Erasmus MC, Rotterdam, The Netherlands
J Neurosurg Anesthesiol 21:98-107. 2009..62 days; P=0.012. This study demonstrates that awake craniotomy is likely to be physically and emotionally less stressful than general anesthesia and that amino acid profiling holds promise for monitoring postoperative pain and recovery...
- Inflammatory profile of awake function-controlled craniotomy and craniotomy under general anesthesiaMarkus Klimek
Department of Anesthesiology, Erasmus MC, P O Box 2040, 3000 CA Rotterdam, The Netherlands
Mediators Inflamm 2009:670480. 2009..Awake craniotomy and craniotomy performed under general anesthesia may be associated with different levels of stress. Our aim was to investigate whether those procedures cause different inflammatory responses...
- Antiepileptic drug therapy in the perioperative course of neurosurgical patientsMarkus Klimek
Department of Anesthesiology, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands
Curr Opin Anaesthesiol 23:564-7. 2010..However, the evidence supporting their use is extremely small and adverse events are common. This review highlights the current controversies...
- Can the laryngeal mask airway replace endotracheal tubation for airway control? The argument against the laryngeal mask airwayMarkus Klimek
Centre Location, Erasmus MC University Medical Center, Rotterdam, The Netherlands
Isr Med Assoc J 6:242-4; discussion 244-5. 2004
- Pain in neurosurgically treated patients: a prospective observational studyMarkus Klimek
Department of Anesthesiology, Erasmus University Medical Centre Rotterdam, The Netherlands
J Neurosurg 104:350-9. 2006..This is the first observational study to compare perioperative pain character and intensity in patients undergoing different types of elective neurosurgical procedures...
- [Awake craniotomy for brain tumor resection - what does the anaesthesist do?]Markus Klimek
Kliniken für Anästhesiologie und Notfallmedizin am Erasmus MC, Universitätsklinikum Rotterdam, Niederlande
Anasthesiol Intensivmed Notfallmed Schmerzther 46:386-91. 2011..This article describes the anaesthesiological management at Erasmus MC, University Medical Centre Rotterdam, The Netherlands, in detail...