Oscar H Franco

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. pmc The Polymeal: a more natural, safer, and probably tastier (than the Polypill) strategy to reduce cardiovascular disease by more than 75%
    Oscar H Franco
    Department of Public Health, Erasmus MC University Medical Centre Rotterdam, PO Box 1738, 3000 DR Rotterdam, Netherlands
    BMJ 329:1447-50. 2004
  2. pmc The polypill: at what price would it become cost effective?
    Oscar H Franco
    Department of Public Health, Erasmus MC, University Medical Centre Rotterdam, 3000 DR Rotterdam, Netherlands
    J Epidemiol Community Health 60:213-7. 2006
  3. ncbi Effects of physical activity on life expectancy with cardiovascular disease
    Oscar H Franco
    Department of Public Health, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
    Arch Intern Med 165:2355-60. 2005
  4. pmc Cost effectiveness of statins in coronary heart disease
    Oscar H Franco
    Department of Public Health, Erasmus MC, University Medical Centre Rotterdam, PO Box 1738, office Ee 2006, 3000 DR Rotterdam, Netherlands
    J Epidemiol Community Health 59:927-33. 2005
  5. ncbi Blood pressure in adulthood and life expectancy with cardiovascular disease in men and women: life course analysis
    Oscar H Franco
    Department of Public Health, Erasmus MC, University Medical Center Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    Hypertension 46:280-6. 2005
  6. doi The Rotterdam Study: 2014 objectives and design update
    Albert Hofman
    Department of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Eur J Epidemiol 28:889-926. 2013
  7. doi Arterial stiffness is associated with carotid intraplaque hemorrhage in the general population: the Rotterdam study
    Mariana Selwaness
    From the Departments of Epidemiology M S, G C V, A H, O H F, J C M W, M W V, Radiology Q v d B, A v d L, M W V, Internal Medicine F U S M R, and Cardiology, Biomedical Engineering J J W, Erasmus MC, Rotterdam, The Netherlands
    Arterioscler Thromb Vasc Biol 34:927-32. 2014
  8. doi Comparison of prognosis in unrecognized versus recognized myocardial infarction in men versus women >55 years of age (from the Rotterdam Study)
    Abbas Dehghan
    Department of Epidemiology, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands Electronic address
    Am J Cardiol 113:1-6. 2014
  9. doi Development of a Healthy Aging Score in the Population-Based Rotterdam Study: Evaluating Age and Sex Differences
    Loes Jaspers
    Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands
    J Am Med Dir Assoc . 2017
  10. doi Carotid Atherosclerotic Plaque Characteristics on Magnetic Resonance Imaging Relate With History of Stroke and Coronary Heart Disease
    Mariana Selwaness
    From the Departments of Epidemiology M S, D B, Q v d B, M L P P, M A I, A H, O H F, M W V, Radiology D B, Q v d B, M A I, A v d L, M W V, and Neurology M A I, Erasmus MC, Rotterdam, the Netherlands and Department of Cardiology, Biomedical Engineering, Erasmus MC, Rotterdam, The Netherlands J J W
    Stroke 47:1542-7. 2016

Detail Information

Publications130 found, 100 shown here

  1. pmc The Polymeal: a more natural, safer, and probably tastier (than the Polypill) strategy to reduce cardiovascular disease by more than 75%
    Oscar H Franco
    Department of Public Health, Erasmus MC University Medical Centre Rotterdam, PO Box 1738, 3000 DR Rotterdam, Netherlands
    BMJ 329:1447-50. 2004
    ..The objective of this study was to identify a tastier and safer alternative to the Polypill: the Polymeal...
  2. pmc The polypill: at what price would it become cost effective?
    Oscar H Franco
    Department of Public Health, Erasmus MC, University Medical Centre Rotterdam, 3000 DR Rotterdam, Netherlands
    J Epidemiol Community Health 60:213-7. 2006
    ..The aim of this study was to determine the maximum price of the polypill for it to be a cost effective alternative in the primary prevention of cardiovascular disease...
  3. ncbi Effects of physical activity on life expectancy with cardiovascular disease
    Oscar H Franco
    Department of Public Health, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
    Arch Intern Med 165:2355-60. 2005
    ..Our objective was to calculate the consequences of different physical activity levels after age 50 years on total life expectancy and life expectancy with and without cardiovascular disease...
  4. pmc Cost effectiveness of statins in coronary heart disease
    Oscar H Franco
    Department of Public Health, Erasmus MC, University Medical Centre Rotterdam, PO Box 1738, office Ee 2006, 3000 DR Rotterdam, Netherlands
    J Epidemiol Community Health 59:927-33. 2005
    ..This article reviewed cost effectiveness analyses of statins and sought to synthesise cost effectiveness ratios for categories of risk of coronary heart disease and age...
  5. ncbi Blood pressure in adulthood and life expectancy with cardiovascular disease in men and women: life course analysis
    Oscar H Franco
    Department of Public Health, Erasmus MC, University Medical Center Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    Hypertension 46:280-6. 2005
    ..This effect is larger than estimated previously and affects both sexes similarly. Our findings underline the tremendous importance of preventing high blood pressure and its consequences in the population...
  6. doi The Rotterdam Study: 2014 objectives and design update
    Albert Hofman
    Department of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Eur J Epidemiol 28:889-926. 2013
    ..erasmus-epidemiology.nl/rotterdamstudy ). This article gives the rationale of the study and its design. It also presents a summary of the major findings and an update of the objectives and methods...
  7. doi Arterial stiffness is associated with carotid intraplaque hemorrhage in the general population: the Rotterdam study
    Mariana Selwaness
    From the Departments of Epidemiology M S, G C V, A H, O H F, J C M W, M W V, Radiology Q v d B, A v d L, M W V, Internal Medicine F U S M R, and Cardiology, Biomedical Engineering J J W, Erasmus MC, Rotterdam, The Netherlands
    Arterioscler Thromb Vasc Biol 34:927-32. 2014
    ..In a population-based study, we investigated the association between arterial stiffness and the presence and composition of carotid atherosclerotic plaques...
  8. doi Comparison of prognosis in unrecognized versus recognized myocardial infarction in men versus women >55 years of age (from the Rotterdam Study)
    Abbas Dehghan
    Department of Epidemiology, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands Electronic address
    Am J Cardiol 113:1-6. 2014
    ..In men, the prognosis is as unfavorable as that of patients with recognized MIs. ..
  9. doi Development of a Healthy Aging Score in the Population-Based Rotterdam Study: Evaluating Age and Sex Differences
    Loes Jaspers
    Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands
    J Am Med Dir Assoc . 2017
    ..To develop a healthy aging score (HAS), to assess age and sex differences in HAS, and to evaluate the association of the HAS with survival...
  10. doi Carotid Atherosclerotic Plaque Characteristics on Magnetic Resonance Imaging Relate With History of Stroke and Coronary Heart Disease
    Mariana Selwaness
    From the Departments of Epidemiology M S, D B, Q v d B, M L P P, M A I, A H, O H F, M W V, Radiology D B, Q v d B, M A I, A v d L, M W V, and Neurology M A I, Erasmus MC, Rotterdam, the Netherlands and Department of Cardiology, Biomedical Engineering, Erasmus MC, Rotterdam, The Netherlands J J W
    Stroke 47:1542-7. 2016
    ..We examined whether carotid atherosclerotic wall thickness, stenosis, and plaque composition are related to history of ischemic stroke and coronary heart disease (CHD)...
  11. pmc Serum Magnesium and the Risk of Death From Coronary Heart Disease and Sudden Cardiac Death
    Brenda C T Kieboom
    Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands B T K, M N N, M G L, O H F, A H, B H S Department of Internal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands B T K, R Z, B H S, E J H Inspectorate for Health Care, Utrecht, The Netherlands B T K, B H S
    J Am Heart Assoc 5:. 2016
    ..We studied the association of serum magnesium with coronary heart disease (CHD) mortality and sudden cardiac death (SCD) within the prospective population-based Rotterdam Study, with adjudicated end points and long-term follow-up...
  12. doi The role of DNA methylation in dyslipidaemia: A systematic review
    Kim V E Braun
    Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands Electronic address
    Prog Lipid Res 64:178-191. 2016
    ....
  13. pmc The global impact of non-communicable diseases on macro-economic productivity: a systematic review
    Layal Chaker
    Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Office NA29 16, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Eur J Epidemiol 30:357-95. 2015
    ..The absolute global impact in terms of dollars and DALYs remains an elusive challenge due to the wide heterogeneity in the included studies as well as limited information from low- and middle-income countries. ..
  14. doi The global impact of non-communicable diseases on healthcare spending and national income: a systematic review
    Taulant Muka
    Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Office NA29 16, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Eur J Epidemiol 30:251-77. 2015
    ..However further work is required to standardize more consistently the methods available to assess the economic impact of NCDs and to involve (hitherto under-addressed) LMI populations across the globe...
  15. doi Intracranial carotid artery atherosclerosis and the risk of stroke in whites: the Rotterdam Study
    Daniel Bos
    Department of Radiology, Erasmus Medical Center, Rotterdam, the Netherlands2Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    JAMA Neurol 71:405-11. 2014
    ..Intracranial atherosclerosis represents a relatively unexplored, but potentially important, cause of stroke in a white population...
  16. doi Comparison of application of the ACC/AHA guidelines, Adult Treatment Panel III guidelines, and European Society of Cardiology guidelines for cardiovascular disease prevention in a European cohort
    Maryam Kavousi
    Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
    JAMA 311:1416-23. 2014
    ..5% 10-year hard atherosclerotic cardiovascular disease (ASCVD) risk. Implications of the new guideline's threshold and model have not been addressed in non-US populations or compared with previous guidelines...
  17. pmc Effectiveness calculation in economic analysis: the case of statins for cardiovascular disease prevention
    Oscar H Franco
    Department of Public Health, Erasmus MC, University Medical Centre Rotterdam, Netherlands
    J Epidemiol Community Health 60:839-45. 2006
    ..This report aimed to evaluate the calculation of estimates of effectiveness in cost effectiveness analyses of statins for cardiovascular disease prevention...
  18. doi PROP taster status, food preferences and consumption of high-calorie snacks and sweet beverages among 6-year-old ethnically diverse children
    Anne I Wijtzes
    The Generation R Study Group, Erasmus Medical Center, Rotterdam, The Netherlands
    Matern Child Nutr . 2016
    ..06; 95% CI: 0.92,1.23). Other factors relating to the family food environment may be more important for young children's food preferences and consumption of high-calorie snacks and sweet beverages than their innate taste sensitivity...
  19. ncbi Dietary mineral intake and lung cancer risk: the Rotterdam Study
    Taulant Muka
    Department of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Eur J Nutr . 2016
    ..Limited data are available on the role of mineral intake in the development of lung cancer (LC). We investigated whether dietary calcium, copper, iron, magnesium, selenium and zinc intake were associated with LC risk...
  20. doi Sex Steroids, Sex Hormone-Binding Globulin and Cardiovascular Health in Men and Postmenopausal Women: The Rotterdam Study
    Loes Jaspers
    Department of Epidemiology L J, K D, T M, J C K d J, O H F, A H, M K, Erasmus University Medical Centre, Rotterdam, 3000 CA The Netherlands Division of Reproductive Medicine C M, J S E L, Department of Obstetrics and Gynaecology, Erasmus University Medical Centre, Rotterdam, 3000 CA The Netherlands Leiden University College J C K d J, The Hague, 3595 DG The Netherlands and Department of Epidemiology A H, Harvard T H Chan School of Public Health, Boston, Massachusetts 02138
    J Clin Endocrinol Metab 101:2844-52. 2016
    ..The concept of cardiovascular health was recently introduced. Sex steroids and sex hormone-binding globulin (SHBG) influence different health domains, but no studies assessed their role in cardiovascular health...
  21. pmc The Generation R Study: design and cohort update 2017
    Marjolein N Kooijman
    The Generation R Study Group NA 2915, Erasmus Medical Center, University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Eur J Epidemiol . 2017
    ..Genome and epigenome wide association screens are available. Eventually, results from the Generation R Study contribute to the development of strategies for optimizing health and healthcare for pregnant women and children...
  22. doi Vitamin D and body composition in the elderly
    Anna Vitezova
    Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, The Netherlands Electronic address
    Clin Nutr . 2016
    ..To investigate the association between vitamin D status and body composition in the elderly...
  23. doi The functions of estrogen receptor beta in the female brain: A systematic review
    Kris G Vargas
    Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands
    Maturitas 93:41-57. 2016
    ..However, to establish potential therapeutic and preventive strategies targeting ERβ, future studies should be conducted in humans to further our understanding of the importance of ERβ in women's mental and cognitive health...
  24. doi ABCB1 gene variants, digoxin and risk of sudden cardiac death in a general population
    Maartje N Niemeijer
    Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
    Heart 101:1973-9. 2015
    ..We aimed to investigate the interaction between variants within the ABCB1 gene and digoxin on the risk of sudden cardiac death (SCD)...
  25. pmc The Rotterdam Study: 2016 objectives and design update
    Albert Hofman
    Department of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Eur J Epidemiol 30:661-708. 2015
    ..erasmus-epidemiology.nl/rotterdamstudy ). This article gives the rationale of the study and its design. It also presents a summary of the major findings and an update of the objectives and methods...
  26. doi Subclinical Abnormalities in Echocardiographic Parameters and Risk of Sudden Cardiac Death in a General Population: The Rotterdam Study
    Maartje N Niemeijer
    Department of Epidemiology, Erasmus Medical Center University Medical Center Rotterdam, Rotterdam, The Netherlands
    J Card Fail 22:17-23. 2016
    ..Less well known is whether subclinical cardiac dysfunction is also a risk factor for SCD. Our objective was to assess the association between echocardiographic parameters and SCD in a community-dwelling population free of heart failure...
  27. pmc The Association between Metabolic Syndrome, Bone Mineral Density, Hip Bone Geometry and Fracture Risk: The Rotterdam Study
    Taulant Muka
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    PLoS ONE 10:e0129116. 2015
    ..In conclusion, women with MS had higher FN-BMD independent of BMI. The glucose component of MS was associated with high FN-BMD in both genders, highlighting the need to preserve glycemic control to prevent skeletal complications. ..
  28. pmc Sex differences in lifetime risk and first manifestation of cardiovascular disease: prospective population based cohort study
    Maarten J G Leening
    Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands Department of Cardiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands Department of Epidemiology, Harvard School of Public Health, Boston, MA, US
    BMJ 349:g5992. 2014
    ..To evaluate differences in first manifestations of cardiovascular disease between men and women in a competing risks framework...
  29. doi Serum potassium levels and the risk of atrial fibrillation: the Rotterdam Study
    Bouwe P Krijthe
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands Netherlands Consortium for Healthy Aging NCHA, The Netherlands
    Int J Cardiol 168:5411-5. 2013
    ..Little is known about the association of serum potassium with atrial fibrillation. The objective of this study was to investigate the association of serum potassium and the risk of atrial fibrillation in a population based setting...
  30. ncbi Physical activity and life expectancy with and without diabetes: life table analysis of the Framingham Heart Study
    Jacqueline T Jonker
    Department of Public Health, Erasmus Medical Center, P O Box 1738, 3000 DR, Rotterdam, Netherlands
    Diabetes Care 29:38-43. 2006
    ..Our aim is to calculate the differences in life expectancy with and without type 2 diabetes associated with different levels of physical activity...
  31. doi Comparison of ACC/AHA and ESC Guideline Recommendations Following Trial Evidence for Statin Use in Primary Prevention of Cardiovascular Disease: Results From the Population-Based Rotterdam Study
    Jelena Pavlovic
    Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
    JAMA Cardiol 1:708-13. 2016
    ..However, randomized clinical trials (RCTs) for statin use have included participants with specific risk-factor profiles...
  32. doi Thyroid Function Characteristics and Determinants: The Rotterdam Study
    Layal Chaker
    1 Rotterdam Thyroid Center, Erasmus University Medical Center, Rotterdam, The Netherlands
    Thyroid 26:1195-204. 2016
    ....
  33. doi Use of Plant-Based Therapies and Menopausal Symptoms: A Systematic Review and Meta-analysis
    Oscar H Franco
    Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands
    JAMA 315:2554-63. 2016
    ..Between 40% and 50% of women in Western countries use complementary therapies to manage menopausal symptoms...
  34. ncbi ADAMTS13 activity as a novel risk factor for incident type 2 diabetes mellitus: a population-based cohort study
    Paul S de Vries
    Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands
    Diabetologia . 2016
    ..VWF has been associated with an increased risk of incident type 2 diabetes mellitus. Here, we determine whether ADAMTS13 activity and VWF antigen are associated with incident diabetes...
  35. pmc Gait patterns associated with thyroid function: The Rotterdam Study
    Arjola Bano
    Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands
    Sci Rep 6:38912. 2016
    ..In euthyroid participants, higher thyroid function was associated with worse gait patterns. In conclusion, both low and high thyroid function are associated with alterations in Global gait, Tandem, Base of support and velocity...
  36. doi 25-Hydroxyvitamin D concentrations, asthma and eczema in childhood: The generation R study
    Ilse I M Tromp
    From The Generation R Study Group, The Netherlands Departments of Pediatrics, Erasmus University, Rotterdam, The Netherlands
    Clin Nutr . 2016
    ....
  37. doi Maternal weight status, diet, and supplement use as determinants of breastfeeding and complementary feeding: a systematic review and meta-analysis
    Audry H Garcia
    A H Garcia, T Voortman, C P Baena, T Muka, L Jaspers, M J Tielemans, J Troup, O H Franco, and E H van den Hooven are with the Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, the Netherlands C P Baena is with the Pontifical Catholic University of Parana, Curitiba, Brazil R Chowdhurry and S Warnakula are with the Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom W M Bramer is with the Medical Library, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Nutr Rev 74:490-516. 2016
    ..Infant feeding practices are influenced by maternal factors...
  38. ncbi Aortic Valve Calcification and the Risk of dementia: A Population-Based Study
    Frank J Wolters
    Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands
    J Alzheimers Dis 55:893-897. 2016
    ..89 (95% confidence interval (CI):0.63;1.26)]. Presence of AVC was not associated with cognitive decline on any of the cognitive tests, nor with a measure of global cognition...
  39. ncbi Physical activity types and life expectancy with and without cardiovascular disease: the Rotterdam Study
    Klodian Dhana
    Department of Epidemiology, University Medical Center Rotterdam, Rotterdam, The Netherlands Department of Nutrition, Harvard T H Chan School of Public Health, Boston, MA, USA
    J Public Health (Oxf) . 2016
    ..We aimed to determine the contribution of specific physical activity (PA) types (i.e. walking, cycling, domestic work, sports and gardening) on total life expectancy (LE) and LE with and without cardiovascular disease (CVD)...
  40. doi von Willebrand Factor, ADAMTS13 Activity, and Decline in Kidney Function: A Population-Based Cohort Study
    Sanaz Sedaghat
    Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands
    Am J Kidney Dis 68:726-732. 2016
    ..Altered levels of von Willebrand factor (vWF) and ADAMTS13 can promote thrombosis and disturb blood flow in kidney microcirculations. We investigated the association of serum vWF:ADAMTS13 ratio in relation to decline in kidney function...
  41. pmc Obesity and Life Expectancy with and without Diabetes in Adults Aged 55 Years and Older in the Netherlands: A Prospective Cohort Study
    Klodian Dhana
    Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    PLoS Med 13:e1002086. 2016
    ..We aimed to determine the association of overweight and obesity with the number of years lived with and without diabetes in a middle-aged and elderly population...
  42. pmc A priori and a posteriori dietary patterns at the age of 1 year and body composition at the age of 6 years: the Generation R Study
    Trudy Voortman
    The Generation R Study Group, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    Eur J Epidemiol 31:775-83. 2016
    ..Our results suggest that different a priori- and a posteriori-derived health-conscious dietary patterns in early childhood are associated with a higher fat-free mass, but not with fat mass, in later childhood. ..
  43. doi Comparison of Atherosclerotic Calcification in Major Vessel Beds on the Risk of All-Cause and Cause-Specific Mortality: The Rotterdam Study
    Daniel Bos
    From the Departments of Radiology D B, A L, M W V, M A I, Epidemiology D B, M J G L, M K, A H, O H F, M W V, M A I, Cardiology M J G L, and Neurology M A I, Erasmus MC, Rotterdam, The Netherlands
    Circ Cardiovasc Imaging 8:. 2015
    ..Atherosclerosis is a major contributor to global morbidity and mortality. Although atherosclerosis is a systemic disease, its burden varies considerably across vessel beds, which may translate into differences in mortality risk...
  44. pmc Association of Vasomotor and Other Menopausal Symptoms with Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis
    Taulant Muka
    Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    PLoS ONE 11:e0157417. 2016
    ..Vasomotor symptoms (hot flushes and night sweats) and other symptoms, including depression, anxiety and panic attacks, are commonly experienced by menopausal women and have been associated with an unfavourable cardiovascular risk profile...
  45. doi Thyroid Function and the Risk of Nonalcoholic Fatty Liver Disease: The Rotterdam Study
    Arjola Bano
    Department of Internal Medicine A B, L C, R P P, Erasmus University Medical Center, 3015 GE, Rotterdam, The Netherlands Rotterdam Thyroid Center A B, L C, R P P, Erasmus University Medical Center, 3015 GE, Rotterdam, The Netherlands Department of Epidemiology A B, L C, E P C P, A H, A D, O H F, S d M, R P P, Erasmus University Medical Center, 3015 GE, Rotterdam, The Netherlands Department of Gastroenterology and Hepatology E P C P, H L A J, S d M, Erasmus University Medical Center, 3015 GE, Rotterdam, The Netherlands and Toronto Centre for Liver Disease H L A J, Toronto Western and General Hospital, University Health Network, Toronto, Ontario, M5G 2C4 Canada
    J Clin Endocrinol Metab 101:3204-11. 2016
    ..Although thyroid function is associated with several risk factors of nonalcoholic fatty liver disease (NAFLD), its role in NAFLD development remains unclear...
  46. doi Dietary polyunsaturated fatty acids intake modifies the positive association between serum total cholesterol and colorectal cancer risk: the Rotterdam Study
    Taulant Muka
    Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands
    J Epidemiol Community Health 70:881-7. 2016
    ..We aimed to investigate the association between serum total cholesterol with CRC. Furthermore, we investigated whether this association was modified by intake of dietary polyunsaturated fatty acids (PUFAs)...
  47. doi Serum Levels of Apolipoproteins and Incident Type 2 Diabetes: A Prospective Cohort Study
    Adela Brahimaj
    Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands
    Diabetes Care . 2016
    ..We aimed to investigate the role of serum levels of various apolipoproteins on the risk for type 2 diabetes (T2D)...
  48. doi Bone health and coronary artery calcification: The Rotterdam Study
    Natalia Campos-Obando
    Department of Internal Medicine, Erasmus MC, 3000 CA Rotterdam, The Netherlands
    Atherosclerosis 241:278-83. 2015
    ..The aims of the present study were to investigate the associations between coronary artery calcification (CAC) and BMD change, BMD and fracture risk in elderly subjects of the population-based Rotterdam Study...
  49. pmc Vitamin D and C-Reactive Protein: A Mendelian Randomization Study
    Marte C Liefaard
    Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands Netherlands Institute for Health Sciences, Rotterdam, The Netherlands
    PLoS ONE 10:e0131740. 2015
    ..001; p = 0.998). In conclusion, higher levels of Vitamin D are associated with lower levels of C-reactive protein. In this study we did not find evidence for this to be the result of a causal relationship. ..
  50. pmc Protein intake in infancy and kidney size and function at the age of 6 years: The Generation R Study
    Trudy Voortman
    The Generation R Study Group, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    Pediatr Nephrol 30:1825-33. 2015
    ..High protein intake has been linked to kidney growth and function. Whether protein intake is related to kidney outcomes in healthy children is unclear...
  51. doi Coexistence of Calcification, Intraplaque Hemorrhage and Lipid Core within the Asymptomatic Atherosclerotic Carotid Plaque: The Rotterdam Study
    Quirijn J A van den Bouwhuijsen
    Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands
    Cerebrovasc Dis 39:319-24. 2015
    ..Therefore, in this study we set out to investigate the coexistence of intraplaque calcification, hemorrhage and lipid core within the carotid artery using a multi-modality imaging approach...
  52. doi Effects of choline on health across the life course: a systematic review
    Elisabeth T M Leermakers
    E T M Leermakers, E M Moreira, J C Kiefte de Jong, S K L Darweesh, T Visser, T Voortman, P K Bautista, J F Felix, and O H Franco are with the Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, the Netherlands R Chowdhury and D Gorman are with the Department of Public Health and Primary Care, Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, CB1 8RN, United Kingdom W M Bramer is with the Medical Library, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    Nutr Rev 73:500-22. 2015
    ..There has been concern, however, that it may influence blood lipid levels because it is an essential component of very-low-density lipoproteins...
  53. doi Drugs and ventricular repolarization in a general population: the Rotterdam Study
    Maartje N Niemeijer
    Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
    Pharmacoepidemiol Drug Saf 24:1036-41. 2015
    ..Regulatory agencies recommend avoiding concomitant use of multiple QTc-prolonging drugs, but evidence is lacking to what degree ventricular repolarization is influenced by concomitant use of these drugs...
  54. doi Early origins of ethnic disparities in cardiovascular risk factors
    Olta Gishti
    The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands Department of Epidemiology, Rotterdam, The Netherlands Department of Pediatrics, Erasmus University Medical Center, Rotterdam, The Netherlands
    Prev Med 76:84-91. 2015
    ..Not much is known about the ethnic differences in cardiovascular risk factors during childhood in European countries. We examined the ethnic differences in childhood cardiovascular risk factors in the Netherlands...
  55. doi Meal-Skipping Behaviors and Body Fat in 6-Year-Old Children
    Anne I Wijtzes
    Generation R Study Group, Erasmus Medical Center, Rotterdam, The Netherlands Department of Public Health, Erasmus Medical Center, Rotterdam, The Netherlands Electronic address
    J Pediatr 168:118-25.e2. 2016
    ..To assess the prospective associations of breakfast, lunch, and dinner skipping at age 4 years with body fat (ie, percent fat mass, body mass index [BMI], and weight status) at age 6 years...
  56. doi Lifetime risk of developing impaired glucose metabolism and eventual progression from prediabetes to type 2 diabetes: a prospective cohort study
    Symen Ligthart
    Department of Epidemiology, Erasmus University Medical Center, Rotterdam, Netherlands
    Lancet Diabetes Endocrinol 4:44-51. 2016
    ..We aimed to calculate the lifetime risk of the full range of glucose impairments, from normoglycaemia to prediabetes, type 2 diabetes, and eventual insulin use...
  57. doi Atherosclerotic calcification is related to a higher risk of dementia and cognitive decline
    Daniel Bos
    Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Alzheimers Dement 11:639-47.e1. 2015
    ..Longitudinal data on the role of atherosclerosis in different vessel beds in the etiology of cognitive impairment and dementia are scarce and inconsistent...
  58. doi Heritability and Genome-Wide Association Analyses of Intracranial Carotid Artery Calcification: The Rotterdam Study
    Hieab H H Adams
    From the Departments of Epidemiology H H H A, M A I, M W V, A H, A G U, C M v D, O H F, D B, Radiology M A I, M W V, A C v D, A v d L, D B, Neurology M A I, A C v D, P J K, and Internal Medicine A G U, Erasmus MC, Rotterdam, The Netherlands and Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, MA A H
    Stroke 47:912-7. 2016
    ..Intracranial carotid artery calcification (ICAC) is one of the most important risk factors for stroke. Although several environmental risk factors for ICAC have been identified, its genetic background remains unclear...
  59. doi Kidney function and microstructural integrity of brain white matter
    Sanaz Sedaghat
    From the Departments of Epidemiology S S, L G M C, M D G, A H, O H F, M W V, A D, M A I, Radiology L G M C, M D G, A v d L, M W V, M A I, Medical informatics M d G, Internal Medicine E J H, and Neurology M A I, Erasmus University Medical Center, Rotterdam, The Netherlands
    Neurology 85:154-61. 2015
    ..To investigate the association of kidney function with white matter microstructural integrity...
  60. doi Bidirectional associations between fussy eating and functional constipation in preschool children
    Anne Tharner
    Department of Epidemiology, Erasmus Medical Center, Erasmus University Rotterdam, Rotterdam, The Netherlands Department of Child and Adolescent Psychiatry Psychology, Erasmus Medical Center, Erasmus University Rotterdam, Rotterdam, The Netherlands Electronic address
    J Pediatr 166:91-6. 2015
    ..To examine bidirectional associations between a child's fussy eating behavior and functional constipation...
  61. doi The Generation R Study: Biobank update 2015
    Claudia J Kruithof
    The Generation R Study Group NA 2915, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Eur J Epidemiol 29:911-27. 2014
    ....
  62. pmc Serum uric acid and chronic kidney disease: the role of hypertension
    Sanaz Sedaghat
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    PLoS ONE 8:e76827. 2013
    ..In this population-based study we investigated the association between serum uric acid and decline in renal function and tested whether hypertension moderates this association...
  63. doi Bone mineral density and chronic lung disease mortality: the rotterdam study
    Natalia Campos-Obando
    Departments of Internal Medicine N C O, M C C B, L O, B H C S, H T, F R, A G U, M C Z and Epidemiology M C C B, O H F, B H C S, G G B, L L, A H, F R, A G U, M C Z, Erasmus MC, 3000 CA Rotterdam, The Netherlands Department of Respiratory Medicine G G B, L L, Ghent University Hospital, B 9000 Ghent, Belgium Departments of Respiratory Medicine G G B and Psychiatric Epidemiology H T, Erasmus MC, 3000 CA Rotterdam, The Netherlands and Netherlands Genomics Initiative Sponsored Netherlands Consortium for Healthy Ageing M C C B, L O, O H F, A H, F R, A G U, M C Z, 2300 RC Leiden, The Netherlands
    J Clin Endocrinol Metab 99:1834-42. 2014
    ..Low bone mineral density (BMD) has been associated with increased all-cause mortality. Cause-specific mortality studies have been controversial...
  64. doi Risk scores of common genetic variants for lipid levels influence atherosclerosis and incident coronary heart disease
    Aaron Isaacs
    Genetic Epidemiology Unit, Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Arterioscler Thromb Vasc Biol 33:2233-9. 2013
    ..We tested the hypothesis that the cumulative effects of common genetic variants for lipids are collectively associated with subclinical atherosclerosis and incident coronary heart disease...
  65. doi Psoriasis is not associated with atherosclerosis and incident cardiovascular events: the Rotterdam Study
    Emmilia A Dowlatshahi
    Department of Dermatology, Erasmus University Medical Center, Rotterdam, The Netherlands
    J Invest Dermatol 133:2347-54. 2013
    ..Psoriasis patients with predominantly mild disease from the general population are as likely to develop atherosclerosis and cardiovascular events as subjects without psoriasis. ..
  66. pmc Living healthier for longer: comparative effects of three heart-healthy behaviors on life expectancy with and without cardiovascular disease
    Wilma J Nusselder
    Department of Public Health, Erasmus MC, University Medical Center Rotterdam, PO Box 2040, 3000 CA Rotterdam, Rotterdam, The Netherlands
    BMC Public Health 9:487. 2009
    ..We aimed to calculate and compare the effects of non-smoking, normal weight and physical activity in middle-aged populations on life expectancy with and without cardiovascular disease...
  67. ncbi Associations of diabetes mellitus with total life expectancy and life expectancy with and without cardiovascular disease
    Oscar H Franco
    Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Arch Intern Med 167:1145-51. 2007
    ..We aimed to calculate the association of diabetes after age 50 years with life expectancy and the number of years lived with and without CVD...
  68. pmc Prevalence of Pulmonary Hypertension in the General Population: The Rotterdam Study
    Eduardo M Moreira
    Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands School of Medicine, Pontifical Catholic University of Parana, Curitiba, Brazil
    PLoS ONE 10:e0130072. 2015
    ..We aimed to describe the distribution of echocardiographically-assessed pulmonary artery systolic pressure (ePASP) in the general population, to estimate the prevalence of pulmonary hypertension, and to identify associated factors...
  69. pmc Development of a Food Group-Based Diet Score and Its Association with Bone Mineral Density in the Elderly: The Rotterdam Study
    Ester A L de Jonge
    Department of Epidemiology, Erasmus MC, University Medical Centre, P O Box 2040, 3000 CA, Rotterdam, The Netherlands
    Nutrients 7:6974-90. 2015
    ..The food groups included in our BMD-Diet Score could be considered in the development of future dietary guidelines for healthy ageing. ..
  70. doi Incremental predictive value of 152 single nucleotide polymorphisms in the 10-year risk prediction of incident coronary heart disease: the Rotterdam Study
    Paul S de Vries
    Department of Epidemiology, and Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
    Int J Epidemiol 44:682-8. 2015
    ..To examine the incremental predictive value of genetic risk scores of coronary heart disease (CHD) in the 10-year risk prediction of incident CHD...
  71. doi The N-terminal pro B-type natriuretic peptide, and risk of dementia and cognitive decline: a 10-year follow-up study in the general population
    Saira Saeed Mirza
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    J Neurol Neurosurg Psychiatry 87:356-62. 2016
    ..However, how NT-proBNP relates to incident dementia and cognitive-decline in community-dwelling persons is unknown...
  72. pmc A Priori and a Posteriori Dietary Patterns during Pregnancy and Gestational Weight Gain: The Generation R Study
    Myrte J Tielemans
    Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    Nutrients 7:9383-99. 2015
    ..01 (95% CI -0.02; -0.00) per SD). The a priori-defined pattern was not associated with GWG. To conclude, specific dietary patterns may play a role in early pregnancy but are not consistently associated with GWG. ..
  73. doi Breastfeeding duration and non-verbal IQ in children
    Ayesha Sajjad
    The Generation R Study Group, Erasmus MC, Rotterdam, The Netherlands Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands
    J Epidemiol Community Health 69:775-81. 2015
    ..However, due to methodological challenges, such as confounding, recall bias or insufficient power, the mechanism and nature of the relation remains subject to debate...
  74. doi Role of Prestroke Vascular Pathology in Long-Term Prognosis After Stroke: The Rotterdam Study
    Marileen L P Portegies
    From the Department of Epidemiology M L P P, M J B, A H, J H, O H F, M A I, Neurology M L P P, P J K, M A I, and Radiology M A I, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Stroke 47:80-7. 2016
    ..Within the population-based Rotterdam Study, we examined the proportion of deaths after stroke that are attributable to pre-existent cardiovascular risk factors before stroke (the population attributable risk)...
  75. doi Proton pump inhibitors and hypomagnesemia in the general population: a population-based cohort study
    Brenda C T Kieboom
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands Inspectorate of Health Care, Utrecht, The Netherlands
    Am J Kidney Dis 66:775-82. 2015
    ..Our objective was to determine whether PPI use is associated with hypomagnesemia in the general population and whether this is also found in histamine 2 receptor antagonist (H2RA) users...
  76. pmc The potential for prevention of dementia across two decades: the prospective, population-based Rotterdam Study
    Renée F A G de Bruijn
    Department of Epidemiology, Erasmus University Medical Center, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands
    BMC Med 13:132. 2015
    ..e., population attributable risk (PAR). Furthermore, we studied whether the PAR has changed across the last two decades...
  77. doi Associations of breast-feeding patterns and introduction of solid foods with childhood bone mass: The Generation R Study
    Edith H van den Hooven
    1Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Br J Nutr 115:1024-32. 2016
    ....
  78. doi Association of uric acid genetic risk score with blood pressure: the Rotterdam study
    Sanaz Sedaghat
    Departments of Epidemiology S S, R P, A G U, A H, B H Ch S, O H F, A D, M A I, Internal Medicine A G U, Radiology M A I, and Neurology M A I, Erasmus University Medical Center, Rotterdam, The Netherlands
    Hypertension 64:1061-6. 2014
    ..Our study suggests that genome wide association study's findings can be associated with an intermediate factor or have a pleiotropic role and, therefore, should be applied for Mendelian Randomization with caution. ..
  79. doi Sedentary behaviors, physical activity behaviors, and body fat in 6-year-old children: the Generation R Study
    Anne I Wijtzes
    The Generation R Study Group, Erasmus Medical Center, Rotterdam, The Netherlands
    Int J Behav Nutr Phys Act 11:96. 2014
    ..e., percent fat mass, body mass index (BMI) standard deviation scores, and weight status (normal weight, overweight)...
  80. doi Atherosclerotic plaque in the left carotid artery is more vulnerable than in the right
    Mariana Selwaness
    From the Departments of Epidemiology M S, Q v d B, R S v O, A H, O H F, M V, Radiology Q v d B, A v d L, M V, and Cardiology J J W, Erasmus MC, Rotterdam, The Netherlands
    Stroke 45:3226-30. 2014
    ..It is unknown whether this asymmetrical prevalence relates to differences in carotid atherosclerosis. We compared atherosclerotic plaque prevalence, severity, and composition between left and right carotid arteries...
  81. pmc Thyroid function and age-related macular degeneration: a prospective population-based cohort study--the Rotterdam Study
    Layal Chaker
    Rotterdam Thyroid Center, Erasmus University Medical Center, Rotterdam, The Netherlands
    BMC Med 13:94. 2015
    ..The association between thyroid function and age-related macular degeneration (AMD) has not been investigated in the general population...
  82. doi Association of renal function with vascular stiffness in older adults: the Rotterdam study
    Sanaz Sedaghat
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Age Ageing 43:827-33. 2014
    ..A potential mechanism linking cardiovascular disease to chronic kidney disease might be the change in arterial elasticity. We aim to determine the association between renal function and arterial stiffness in older subjects...
  83. pmc Toward an operative diagnosis of fussy/picky eating: a latent profile approach in a population-based cohort
    Anne Tharner
    Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands
    Int J Behav Nutr Phys Act 11:14. 2014
    ..Definitions and assessment methods of fussy/picky eating are heterogeneous and remain unclear.We aimed to identify an eating behavior profile reflecting fussy/picky eating in children and to describe characteristics of fussy eaters...
  84. doi Performance of Framingham cardiovascular disease (CVD) predictions in the Rotterdam Study taking into account competing risks and disentangling CVD into coronary heart disease (CHD) and stroke
    Bob J H van Kempen
    Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands Department of Radiology, Erasmus MC, Rotterdam, The Netherlands
    Int J Cardiol 171:413-8. 2014
    ....
  85. pmc First trimester fetal growth restriction and cardiovascular risk factors in school age children: population based cohort study
    Vincent W V Jaddoe
    The Generation R Study Group, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, Netherlands
    BMJ 348:g14. 2014
    ..To examine whether first trimester fetal growth restriction correlates with cardiovascular outcomes in childhood...
  86. doi Fish consumption in infancy and asthma-like symptoms at preschool age
    Jessica C Kiefte-de Jong
    The Generation R Study Group, Erasmus Medical Center, Rotterdam, The Netherlands
    Pediatrics 130:1060-8. 2012
    ..To assess whether timing of introduction of fish and the amount of fish consumption in infancy were associated with asthmalike symptoms at preschool age...
  87. ncbi Primary prevention of cardiovascular disease: cost-effectiveness comparison
    Oscar H Franco
    Department of Public Health, University Medical Center Rotterdam, 50 Dr Molewaterplein, 3000 CA Rotterdam, Zuid Holland
    Int J Technol Assess Health Care 23:71-9. 2007
    ..The aim of this study was to evaluate the cost-effectiveness of four risk-lowering interventions (smoking cessation, antihypertensives, aspirin, and statins) in primary prevention of cardiovascular disease...
  88. pmc Longitudinal association between preschool fussy eating and body composition at 6 years of age: The Generation R Study
    Lisanne M de Barse
    The Generation R Study Group, Erasmus MC University Medical Center, PO Box 2040, 3000, CA, Rotterdam, The Netherlands
    Int J Behav Nutr Phys Act 12:153. 2015
    ..We aimed to examine whether fussy eating at age 4 years is longitudinally related to body mass index (BMI), fat mass index (FMI) and fat-free mass index (FFMI) at 6 years of age...
  89. doi Estrogen receptor β actions in the female cardiovascular system: A systematic review of animal and human studies
    Taulant Muka
    Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands Electronic address
    Maturitas 86:28-43. 2016
    ..ERβ seems to possess multiple functions in the female cardiovascular system. Further studies are needed to evaluate whether isoform-selective ERβ-ligands might contribute to cardiovascular disease prevention. ..
  90. doi Association Between Atrial Fibrillation and Dementia in the General Population
    Renée F A G de Bruijn
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands2Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
    JAMA Neurol 72:1288-94. 2015
    ..However, longitudinal studies assessing the association between AF and dementia have shown inconsistent results...
  91. doi Coffee consumption and incident dementia
    Saira Saeed Mirza
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Eur J Epidemiol 29:735-41. 2014
    ..Our data suggest that coffee consumption is not associated with incident dementia during long-term. The protective association observed in the short-term might be driven by reverse causality. ..
  92. pmc Associations of heart failure with sleep quality: the Rotterdam Study
    Lisette A Zuurbier
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    J Clin Sleep Med 11:117-21. 2015
    ..The prevalence of sleep disturbances and heart failure increases with age. We aimed to evaluate the associations of incident heart failure and cardiac dysfunction with changes in sleep quality...
  93. doi Effects of protein intake on blood pressure, insulin sensitivity and blood lipids in children: a systematic review
    Trudy Voortman
    Department of Epidemiology, Erasmus MC, University Medical Center, PO Box 2040, 3000CA, Rotterdam, The Netherlands
    Br J Nutr 113:383-402. 2015
    ..Future studies could be improved by adequately adjusting for key confounders such as energy intake and obesity. ..
  94. doi Declining incidence of sudden cardiac death from 1990-2010 in a general middle-aged and elderly population: The Rotterdam Study
    Maartje N Niemeijer
    Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
    Heart Rhythm 12:123-9. 2015
    ..Although sudden cardiac death (SCD) is relatively common, contemporary data on its incidence are lacking...
  95. doi First-trimester maternal protein intake and childhood kidney outcomes: the Generation R Study
    Kozeta Miliku
    The Generation R Study Group and the Departments of Epidemiology and Pediatrics, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    Am J Clin Nutr 102:123-9. 2015
    ..Nutritional exposures during in utero development may have long-lasting consequences for postnatal renal health. Animal studies suggest that specifically maternal dietary protein intake during pregnancy influences childhood kidney function...
  96. pmc Predictive value of updating Framingham risk scores with novel risk markers in the U.S. general population
    Bart S Ferket
    Department of Epidemiology, Erasmus MC, Rotterdam, The Netherlands Department of Radiology, Erasmus MC, Rotterdam, The Netherlands
    PLoS ONE 9:e88312. 2014
    ..Their impact in the U.S. general population is however uncertain. Our aim was to estimate the predictive value of four novel cardiovascular risk markers for the U.S. general population...
  97. doi Unrecognized myocardial infarction and risk of atrial fibrillation: the Rotterdam Study
    Bouwe P Krijthe
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands Netherlands Consortium for Healthy Aging NCHA, The Netherlands
    Int J Cardiol 168:1453-7. 2013
    ..The objective of this study was to investigate whether unrecognized myocardial infarction was associated with an increased risk of atrial fibrillation in a prospective population-based cohort study...
  98. doi The association between physical activity and dementia in an elderly population: the Rotterdam Study
    Renée F A G de Bruijn
    Department of Epidemiology, Erasmus MC University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Eur J Epidemiol 28:277-83. 2013
    ..This association was confined to follow-up for up to 4 years and not to longer follow-up, suggesting either a role for reverse causality or only a short term effect of late-life physical activity in an elderly population...
  99. doi Maternal first-trimester diet and childhood bone mass: the Generation R Study
    Denise H M Heppe
    Generation R Study Group and the Department of Paediatrics, Erasmus Medical Center, Rotterdam, The Netherlands
    Am J Clin Nutr 98:224-32. 2013
    ..Maternal diet during pregnancy has been suggested to influence bone health in later life...
  100. doi Comparing a marginal structural model with a Cox proportional hazard model to estimate the effect of time-dependent drug use in observational studies: statin use for primary prevention of cardiovascular disease as an example from the Rotterdam Study
    Catherine E de Keyser
    Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, P O Box 2040, 3000 CA, Rotterdam, The Netherlands
    Eur J Epidemiol 29:841-50. 2014
    ..Confounding remains a hurdle in observational effectiveness research on preventive drugs with a multitude of prescription determinants...
  101. doi Vitamin D deficiency in school-age children is associated with sociodemographic and lifestyle factors
    Trudy Voortman
    Departments of Epidemiology and The Generation R Study Group, Erasmus MC, University Medical Center, Rotterdam, The Netherlands and
    J Nutr 145:791-8. 2015
    ..There is concern about a reemergence of vitamin D deficiency in children in developed countries...