Niels J Driessen

Summary

Affiliation: Eindhoven University of Technology
Country: The Netherlands

Publications

  1. ncbi request reprint Mechanical characterization of anisotropic planar biological soft tissues using finite indentation: experimental feasibility
    Martijn A J Cox
    Department of Biomedical Engineering, Eindhoven University of Technology, P O Box 513, 5600 MB Eindhoven, The Netherlands
    J Biomech 41:422-9. 2008
  2. ncbi request reprint Remodelling of continuously distributed collagen fibres in soft connective tissues
    N J B Driessen
    Department of Biomedical Engineering, Eindhoven University of Technology, W hoog 4 112, PO Box 513, 5600 MB Eindhoven, The Netherlands
    J Biomech 36:1151-8. 2003
  3. ncbi request reprint A structural constitutive model for collagenous cardiovascular tissues incorporating the angular fiber distribution
    Niels J B Driessen
    Eindhoven University of Technology, Department of Biomedical Engineering, PO Box 513, 5600 MB Eindhoven, The Netherlands
    J Biomech Eng 127:494-503. 2005
  4. ncbi request reprint Modeling the mechanics of tissue-engineered human heart valve leaflets
    Niels J B Driessen
    Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
    J Biomech 40:325-34. 2007
  5. ncbi request reprint Mechanical characterization of anisotropic planar biological soft tissues using large indentation: a computational feasibility study
    Martijn A J Cox
    Department of Biomedical Engineering, Eindhoven University of Technology, PO Box 513, 5600 MB Eindhoven, The Netherlands
    J Biomech Eng 128:428-36. 2006
  6. pmc Remodelling of the angular collagen fiber distribution in cardiovascular tissues
    Niels J B Driessen
    Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
    Biomech Model Mechanobiol 7:93-103. 2008
  7. ncbi request reprint Improved prediction of the collagen fiber architecture in the aortic heart valve
    Niels J B Driessen
    Department of Biomedical Engineering, Eindhoven University of Technology, P O Box 513, 5600 MB Eindhoven, The Netherlands
    J Biomech Eng 127:329-36. 2005
  8. ncbi request reprint A computational model for collagen fibre remodelling in the arterial wall
    N J B Driessen
    Department of Biomedical Engineering, Laboratory of Biomechanics and Tissue Engineering, Eindhoven University of Technology, PO Box 513, Building Whoog 4 112, 5600 MB Eindhoven, The Netherlands
    J Theor Biol 226:53-64. 2004
  9. ncbi request reprint Computational analyses of mechanically induced collagen fiber remodeling in the aortic heart valve
    Niels J Driessen
    Eindhoven University of Technology, Department of Biomedical Engineering, Laboratory for Biomechanics and Tissue Engineering, PO Box 513, 5600 MB Eindhoven, The Netherlands
    J Biomech Eng 125:549-57. 2003
  10. doi request reprint Real time, non-invasive assessment of leaflet deformation in heart valve tissue engineering
    J Kortsmit
    Laboratory for Biomechanics and Tissue Engineering, Department of Biomedical Engineering, Eindhoven University of Technology, P O Box 513, Building W hoog 4 105, 5600 MB Eindhoven, The Netherlands
    Ann Biomed Eng 37:532-41. 2009

Detail Information

Publications15

  1. ncbi request reprint Mechanical characterization of anisotropic planar biological soft tissues using finite indentation: experimental feasibility
    Martijn A J Cox
    Department of Biomedical Engineering, Eindhoven University of Technology, P O Box 513, 5600 MB Eindhoven, The Netherlands
    J Biomech 41:422-9. 2008
    ..Digital image correlation (DIC) is used to quantify the anisotropy in the tissue constructs. For both validation steps, material parameters are estimated by inverse fitting of a computational model to the experimental results...
  2. ncbi request reprint Remodelling of continuously distributed collagen fibres in soft connective tissues
    N J B Driessen
    Department of Biomedical Engineering, Eindhoven University of Technology, W hoog 4 112, PO Box 513, 5600 MB Eindhoven, The Netherlands
    J Biomech 36:1151-8. 2003
    ..The model is then applied to analyse remodelling within a closed stented aortic heart valve. The computed preferred fibre orientation runs from commissure to commissure and resembles the fibre directions in the native aortic valve...
  3. ncbi request reprint A structural constitutive model for collagenous cardiovascular tissues incorporating the angular fiber distribution
    Niels J B Driessen
    Eindhoven University of Technology, Department of Biomedical Engineering, PO Box 513, 5600 MB Eindhoven, The Netherlands
    J Biomech Eng 127:494-503. 2005
    ..We expect that the current model offers strong possibilities to further investigate the complex mechanical behavior of cardiovascular tissues, including their response to mechanical stimuli...
  4. ncbi request reprint Modeling the mechanics of tissue-engineered human heart valve leaflets
    Niels J B Driessen
    Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
    J Biomech 40:325-34. 2007
    ..Compared to native porcine leaflets, the mechanical response of the engineered tissues after four weeks of culturing is more linear, stiffer and less anisotropic...
  5. ncbi request reprint Mechanical characterization of anisotropic planar biological soft tissues using large indentation: a computational feasibility study
    Martijn A J Cox
    Department of Biomedical Engineering, Eindhoven University of Technology, PO Box 513, 5600 MB Eindhoven, The Netherlands
    J Biomech Eng 128:428-36. 2006
    ..The aortic valve leaflet is chosen as a typical example. However, the proposed method is expected to apply for the mechanical characterization of planar soft biological materials in general...
  6. pmc Remodelling of the angular collagen fiber distribution in cardiovascular tissues
    Niels J B Driessen
    Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
    Biomech Model Mechanobiol 7:93-103. 2008
    ..It is expected that the proposed model may be of great potential for the design of improved tissue engineering protocols and may give further insight into the pathophysiology of cardiovascular diseases...
  7. ncbi request reprint Improved prediction of the collagen fiber architecture in the aortic heart valve
    Niels J B Driessen
    Department of Biomedical Engineering, Eindhoven University of Technology, P O Box 513, 5600 MB Eindhoven, The Netherlands
    J Biomech Eng 127:329-36. 2005
    ..The results of the present model might be used to gain further insight into the response of tissue engineered constructs during mechanical conditioning...
  8. ncbi request reprint A computational model for collagen fibre remodelling in the arterial wall
    N J B Driessen
    Department of Biomedical Engineering, Laboratory of Biomechanics and Tissue Engineering, Eindhoven University of Technology, PO Box 513, Building Whoog 4 112, 5600 MB Eindhoven, The Netherlands
    J Theor Biol 226:53-64. 2004
    ....
  9. ncbi request reprint Computational analyses of mechanically induced collagen fiber remodeling in the aortic heart valve
    Niels J Driessen
    Eindhoven University of Technology, Department of Biomedical Engineering, Laboratory for Biomechanics and Tissue Engineering, PO Box 513, 5600 MB Eindhoven, The Netherlands
    J Biomech Eng 125:549-57. 2003
    ..The results indicate that the computed preferred fiber directions run from commissure to commissure and show a strong resemblance to experimental data from native aortic heart valves...
  10. doi request reprint Real time, non-invasive assessment of leaflet deformation in heart valve tissue engineering
    J Kortsmit
    Laboratory for Biomechanics and Tissue Engineering, Department of Biomedical Engineering, Eindhoven University of Technology, P O Box 513, Building W hoog 4 105, 5600 MB Eindhoven, The Netherlands
    Ann Biomed Eng 37:532-41. 2009
    ..Tri-leaflet, stented heart valves were cultured in vitro and during mechanical conditioning, realistic values for volumetric and local deformation were obtained...
  11. ncbi request reprint Prediction of collagen orientation in articular cartilage by a collagen remodeling algorithm
    W Wilson
    Department of Biomedical Engineering, Eindhoven University of Technology, P O Box 513, 5600 MB Eindhoven, The Netherlands
    Osteoarthritis Cartilage 14:1196-202. 2006
    ..The goal of the present study is to evaluate whether a collagen remodeling algorithm based on mechanical loading can be corroborated by the collagen orientation in healthy cartilage...
  12. ncbi request reprint Finite element model of mechanically induced collagen fiber synthesis and degradation in the aortic valve
    Ralf A Boerboom
    Laboratory for Biomechanics and Tissue Engineering, Department of Biomedical Engineering, Eindhoven University of Technology, P O Box 513, 5600 MB Eindhoven, The Netherlands
    Ann Biomed Eng 31:1040-53. 2003
    ..The model predicts the evolution in collagen fiber content and the effect of remodeling on the mechanical properties...
  13. ncbi request reprint Tissue engineering of human heart valve leaflets: a novel bioreactor for a strain-based conditioning approach
    Anita Mol
    Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
    Ann Biomed Eng 33:1778-88. 2005
    ....
  14. pmc Effect of strain magnitude on the tissue properties of engineered cardiovascular constructs
    Ralf A Boerboom
    Department of Biomedical Engineering, Soft Tissue Biomechanics and Engineering, Eindhoven University of Technology, PO Box 513, 5600 MB, Eindhoven, The Netherlands
    Ann Biomed Eng 36:244-53. 2008
    ..The presented model system can be used to systematically optimize culture protocols for engineered cardiovascular tissues...
  15. ncbi request reprint Autologous human tissue-engineered heart valves: prospects for systemic application
    Anita Mol
    Clinic for Cardiovascular Surgery, University Hospital Zurich, Zurich, Switzerland
    Circulation 114:I152-8. 2006
    ..In vivo animal studies of tissue-engineered autologous heart valves have focused on pulmonary valve replacements, leaving the challenge to tissue engineer heart valves suitable for systemic application using human cells...