Maarten R Soeters

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. ncbi request reprint Gender-related differences in the metabolic response to fasting
    Maarten R Soeters
    Department of Endocrinology and Metabolism, Laboratory of Endocrinology, Academic Medical Center, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    J Clin Endocrinol Metab 92:3646-52. 2007
  2. doi request reprint Adaptive reciprocity of lipid and glucose metabolism in human short-term starvation
    Maarten R Soeters
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Am J Physiol Endocrinol Metab 303:E1397-407. 2012
  3. doi request reprint The evolutionary benefit of insulin resistance
    Maarten R Soeters
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    Clin Nutr 31:1002-7. 2012
  4. doi request reprint Characterization of D-3-hydroxybutyrylcarnitine (ketocarnitine): an identified ketosis-induced metabolite
    Maarten R Soeters
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, PO Box 22660, 1100 DD, Amsterdam, The Netherlands
    Metabolism 61:966-73. 2012
  5. ncbi request reprint Optimal management of Graves orbitopathy: a multidisciplinary approach
    M R Soeters
    Departments of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, The Netherlands
    Neth J Med 69:302-8. 2011
  6. ncbi request reprint [HbA1c: target value should remain 7%]
    Maarten R Soeters
    Academisch Medisch Centrum, afd Inwendige Geneeskunde, Amsterdam, The Netherlands
    Ned Tijdschr Geneeskd 154:A2113. 2010
  7. doi request reprint Extended metabolic evaluation of suspected symptomatic hypoglycemia: the prolonged fast and beyond
    Maarten R Soeters
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Metabolism 59:1543-50. 2010
  8. doi request reprint Intermittent fasting does not affect whole-body glucose, lipid, or protein metabolism
    Maarten R Soeters
    Department of Endocrinology and Metabolism, University of Amsterdam, Amsterdam, Netherlands
    Am J Clin Nutr 90:1244-51. 2009
  9. doi request reprint Effects of insulin on ketogenesis following fasting in lean and obese men
    Maarten R Soeters
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Obesity (Silver Spring) 17:1326-31. 2009
  10. doi request reprint Muscle acylcarnitines during short-term fasting in lean healthy men
    Maarten R Soeters
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam 1105 AZ, The Netherlands
    Clin Sci (Lond) 116:585-92. 2009

Collaborators

Detail Information

Publications28

  1. ncbi request reprint Gender-related differences in the metabolic response to fasting
    Maarten R Soeters
    Department of Endocrinology and Metabolism, Laboratory of Endocrinology, Academic Medical Center, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    J Clin Endocrinol Metab 92:3646-52. 2007
    ..During fasting, women have lower plasma glucose levels than men despite higher plasma FFA, suggesting protection from FFA-induced insulin resistance...
  2. doi request reprint Adaptive reciprocity of lipid and glucose metabolism in human short-term starvation
    Maarten R Soeters
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Am J Physiol Endocrinol Metab 303:E1397-407. 2012
    ..The importance of reciprocity in lipid and glucose metabolism during human starvation should be taken into account when studying lipid and glucose metabolism in general and in pathophysiological conditions in particular...
  3. doi request reprint The evolutionary benefit of insulin resistance
    Maarten R Soeters
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    Clin Nutr 31:1002-7. 2012
    ..The metabolic pathways discussed here, should be integrated in the accepted and valid mechanistic events of insulin resistance before interfering with them to promote insulin sensitivity at any cost...
  4. doi request reprint Characterization of D-3-hydroxybutyrylcarnitine (ketocarnitine): an identified ketosis-induced metabolite
    Maarten R Soeters
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, PO Box 22660, 1100 DD, Amsterdam, The Netherlands
    Metabolism 61:966-73. 2012
    ..During fasting, HB-carnitine in muscle is derived mainly from the ketone body D-3HB. The role of D-3HB-carnitine synthesis in metabolism remains to be elucidated...
  5. ncbi request reprint Optimal management of Graves orbitopathy: a multidisciplinary approach
    M R Soeters
    Departments of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, The Netherlands
    Neth J Med 69:302-8. 2011
    ....
  6. ncbi request reprint [HbA1c: target value should remain 7%]
    Maarten R Soeters
    Academisch Medisch Centrum, afd Inwendige Geneeskunde, Amsterdam, The Netherlands
    Ned Tijdschr Geneeskd 154:A2113. 2010
    ..Taking into account historic prospective studies such as the United Kingdom Prospective Diabetes Study, we think the target HbA(1c) should remain 7% or lower in the treatment of diabetes mellitus...
  7. doi request reprint Extended metabolic evaluation of suspected symptomatic hypoglycemia: the prolonged fast and beyond
    Maarten R Soeters
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Metabolism 59:1543-50. 2010
    ..Therefore, the observation of low plasma glucose values in this subgroup of patients probably does not warrant extensive metabolic evaluation...
  8. doi request reprint Intermittent fasting does not affect whole-body glucose, lipid, or protein metabolism
    Maarten R Soeters
    Department of Endocrinology and Metabolism, University of Amsterdam, Amsterdam, Netherlands
    Am J Clin Nutr 90:1244-51. 2009
    ..Such selectivity might be advantageous when adapting to periods of food abundance and food shortage...
  9. doi request reprint Effects of insulin on ketogenesis following fasting in lean and obese men
    Maarten R Soeters
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Obesity (Silver Spring) 17:1326-31. 2009
    ..This implies differential insulin sensitivity of intermediary metabolism in obesity...
  10. doi request reprint Muscle acylcarnitines during short-term fasting in lean healthy men
    Maarten R Soeters
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam 1105 AZ, The Netherlands
    Clin Sci (Lond) 116:585-92. 2009
    ..The higher fatty acid oxidation during hyperinsulinaemia after 62 h compared with 14 h of fasting, although the absolute decrease in fatty acid oxidation was not different, suggests a different set point...
  11. doi request reprint Muscle adaptation to short-term fasting in healthy lean humans
    Maarten R Soeters
    Department of Endocrinology and Metabolism, Academic Medical Center, Amsterdam, The Netherlands
    J Clin Endocrinol Metab 93:2900-3. 2008
    ..Intramyocellular sphingolipids (i.e. ceramide) have been suggested to induce insulin resistance by interfering with the insulin signaling cascade in obesity...
  12. doi request reprint Plasma acylcarnitines inadequately reflect tissue acylcarnitine metabolism
    Marieke G Schooneman
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands Department of Clinical Chemistry, Laboratory Genetic Metabolic Diseases, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Biochim Biophys Acta 1841:987-94. 2014
    ..Therefore, plasma acylcarnitine levels do not reflect tissue levels and should be interpreted with caution. A focus on tissue acylcarnitine levels is warranted in metabolic studies. ..
  13. doi request reprint Combining 123I-metaiodobenzylguanidine SPECT/CT and 18F-FDG PET/CT for the assessment of brown adipose tissue activity in humans during cold exposure
    Wanda M Admiraal
    Department of Internal Medicine, Academic Medical Center, 1100DD Amsterdam, The Netherlands
    J Nucl Med 54:208-12. 2013
    ..Finally, we tried to establish the optimal time interval between (123)I-MIBG administration and subsequent SPECT/CT acquisition to visualize sympathetic stimulation of BAT...
  14. doi request reprint (18)F-fluorodeoxyglucose uptake in brown adipose tissue during insulin-induced hypoglycemia and mild cold exposure in non-diabetic adults
    Josefine E Schopman
    Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands Electronic address
    Metabolism 63:1280-6. 2014
    ..We therefore examined the effect of hypoglycemia on uptake of the labeled glucose analogue (18)F-fluorodeoxyglucose in brown adipose tissue using positron emission tomography and computer tomography...
  15. doi request reprint A short-term high fat diet increases exposure to midazolam and omeprazole in healthy subjects
    Roos Achterbergh
    a Department of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Expert Opin Drug Metab Toxicol 12:715-20. 2016
    ....
  16. doi request reprint Differences in Sympathetic Nervous Stimulation of Brown Adipose Tissue Between the Young and Old, and the Lean and Obese
    Lonneke Bahler
    Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
    J Nucl Med 57:372-7. 2016
    ..We aimed to determine whether this lower metabolic BAT activity in older or overweight individuals can be explained by a lower SNS response to cold...
  17. doi request reprint Impaired insulin action in the liver, but not in adipose tissue or muscle, is a distinct metabolic feature of impaired fasting glucose in obese humans
    Kasper W ter Horst
    Department of Endocrinology and Metabolism, Academic Medical Center, Meibergdreef 9, 1105AZ Amsterdam, The Netherlands
    Metabolism 65:757-63. 2016
    ..We aimed to determine the contribution of these processes to impaired fasting glucose (IFG) levels in obese non-diabetic adults...
  18. doi request reprint Postprandial Plasma Concentrations of Individual Bile Acids and FGF-19 in Patients With Type 2 Diabetes
    David P Sonne
    Center for Diabetes Research D P S, T V, F K K, Gentofte Hospital, University of Copenhagen, 2900 Hellerup, Denmark Department of Endocrinology and Metabolism F S v N, M R S, Academic Medical Center, University of Amsterdam, 1105AZ Amsterdam, The Netherlands Department of Clinical Chemistry W K, Laboratory Genetic Metabolic Diseases, Academic Medical Center, University of Amsterdam, 1012WX Amsterdam, The Netherlands and Novo Nordisk Foundation Center for Basic Metabolic Research and Department of Biomedical Sciences F K K, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark
    J Clin Endocrinol Metab 101:3002-9. 2016
    ..Postprandial activation of ileal FXR leads to secretion of fibroblast growth factor 19 (FGF-19), a gut hormone that may be implicated in postprandial glucose metabolism...
  19. doi request reprint The impact of altered carnitine availability on acylcarnitine metabolism, energy expenditure and glucose tolerance in diet-induced obese mice
    Marieke G Schooneman
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105AZ Amsterdam, The Netherlands Department of Clinical Chemistry, Laboratory Genetic Metabolic Diseases, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105AZ Amsterdam, The Netherlands
    Biochim Biophys Acta 1862:1375-82. 2016
    ..We hypothesized that increasing free carnitine levels by administration of the carnitine precursor γ-butyrobetaine (γBB) could facilitate FAO, thereby improving insulin sensitivity...
  20. doi request reprint Effects of acute dietary weight loss on postprandial plasma bile acid responses in obese insulin resistant subjects
    F Samuel van Nierop
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands
    Clin Nutr . 2016
    ..The BA pool composition is altered in patients with type 2 diabetes and obesity. In this study we used a 2-week very-low-calorie diet (VLCD) to investigate the effects of weight loss on BA pool composition and postprandial dynamics...
  21. doi request reprint Fasting and postprandial activity of brown adipose tissue in healthy men
    Anne Vrieze
    Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
    J Nucl Med 53:1407-10. 2012
    ..The role of brown adipose tissue (BAT) in adult metabolism is poorly understood. This study aimed to examine the differential effects of an overnight fast and the postprandial state on BAT activity...
  22. doi request reprint Transorgan fluxes in a porcine model reveal a central role for liver in acylcarnitine metabolism
    Marieke G Schooneman
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands Department of Clinical Chemistry, Laboratory Genetic Metabolic Diseases, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Am J Physiol Endocrinol Metab 309:E256-64. 2015
    ..These results further clarify the role of different organ compartments in the metabolism of different acylcarnitine species. ..
  23. doi request reprint Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity
    Anne Vrieze
    Department of Medicine, Academic Medical Center, Amsterdam, The Netherlands
    J Hepatol 60:824-31. 2014
    ..Hence, we hypothesized that short term administration of oral antibiotics in humans would affect fecal microbiota composition and subsequently bile acid and glucose metabolism...
  24. ncbi request reprint The added value of oral glucose tolerance testing in pre-diabetes
    Yoeri M Luijf
    Department of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Curr Diabetes Rev 7:56-60. 2011
    ....
  25. doi request reprint Assessment of plasma acylcarnitines before and after weight loss in obese subjects
    Marieke G Schooneman
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands Department of Clinical Chemistry, Laboratory Genetic Metabolic Diseases, Academic Medical Center, University of Amsterdam, The Netherlands Electronic address
    Arch Biochem Biophys 606:73-80. 2016
    ..001). Acylcarnitines did not correlate with clinical parameters of glucose metabolism during weight loss, questioning their role in insulin resistance and type 2 diabetes mellitus. ..
  26. doi request reprint Clinical relevance of the bile acid receptor TGR5 in metabolism
    F Samuel van Nierop
    Department of Endocrinology and Metabolism, Academic Medical Center, Amsterdam, Netherlands
    Lancet Diabetes Endocrinol . 2016
    ..However, evidence of effects on these processes from human studies is less convincing. Ultimately, safe and selective human TGR5 agonists are needed to test the therapeutic potential of TGR5...
  27. doi request reprint Short-term fasting alters cytochrome P450-mediated drug metabolism in humans
    Laureen A Lammers
    Departments of Hospital Pharmacy L A L, R A A M, Medicine R A, J A R, Endocrinology and Metabolism E M d V, F S v N, M R S, A B, and Medical Oncology H J K, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Drug Metab Dispos 43:819-28. 2015
    ..These results demonstrate that short-term fasting alters cytochrome P450-mediated drug metabolism in a nonuniform pattern. Therefore, short-term fasting is another factor affecting cytochrome P450-mediated drug metabolism in humans. ..