Henriette J Scherpbier

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. ncbi request reprint Liver failure in a child receiving highly active antiretroviral therapy and voriconazole
    Henriette J Scherpbier
    Emma Children s Hospital, Academic Medical Centre, Amsterdam, The Netherlands
    Clin Infect Dis 37:828-30. 2003
  2. ncbi request reprint Long-term experience with combination antiretroviral therapy that contains nelfinavir for up to 7 years in a pediatric cohort
    Henriette J Scherpbier
    Emma Children s Hospital, Academic Medical Center, Amsterdam, The Netherlands
    Pediatrics 117:e528-36. 2006
  3. ncbi request reprint Once-daily highly active antiretroviral therapy for HIV-infected children: safety and efficacy of an efavirenz-containing regimen
    Henriette J Scherpbier
    Emma Children s Hospital, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Pediatrics 119:e705-15. 2007
  4. ncbi request reprint A pharmacokinetic and pharmacogenetic study of efavirenz in children: dosing guidelines can result in subtherapeutic concentrations
    Rob ter Heine
    Department of Pharmacy and Pharmacology, Slotervaart Hospital, Amsterdam, The Netherlands
    Antivir Ther 13:779-87. 2008
  5. ncbi request reprint Cytomegalovirus rather than HIV triggers the outgrowth of effector CD8+CD45RA+CD27- T cells in HIV-1-infected children
    Vincent Bekker
    Emma Children s Hospital, Sanquin Research and Landsteiner Laboratory, Academic Medical Center fInternational Antiviral Therapy Evaluation Center, Amsterdam, The Netherlands
    AIDS 19:1025-34. 2005
  6. ncbi request reprint Population pharmacokinetics and pharmacodynamics of nelfinavir and its active metabolite M8 in HIV-1-infected children
    Kristel M L Crommentuyn
    Department of Pharmacy and Pharmacology, Slotervaart Hospital, Amsterdam, The Netherlands
    Pediatr Infect Dis J 25:538-43. 2006
  7. pmc Neurologic abnormalities in HIV-1 infected children in the era of combination antiretroviral therapy
    Lotus A van Arnhem
    Department of Pediatric Hematology, Immunology and Infectious Diseases, Emma Children s Hospital, Academic Medical Centre AMC, Amsterdam, The Netherlands
    PLoS ONE 8:e64398. 2013
  8. ncbi request reprint Viral dynamics after starting first-line HAART in HIV-1-infected children
    Vincent Bekker
    Emma Children s Hospital, Academic Medical Center, The Netherlands
    AIDS 20:517-23. 2006
  9. pmc Long-Term Changes of Subcutaneous Fat Mass in HIV-Infected Children on Antiretroviral Therapy: A Retrospective Analysis of Longitudinal Data from Two Pediatric HIV-Cohorts
    Sophie Cohen
    Department of Paediatric Haematology, Immunology, and Infectious Diseases, Emma Children s Hospital, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    PLoS ONE 10:e0120927. 2015
  10. ncbi request reprint A neonate with macrosomia, cardiomyopathy and hepatomegaly born to an HIV-infected mother
    Mieke H Godfried
    Department of Internal Medicine, AMC, Amsterdam, The Netherlands
    Eur J Pediatr 164:190-2. 2005

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Liver failure in a child receiving highly active antiretroviral therapy and voriconazole
    Henriette J Scherpbier
    Emma Children s Hospital, Academic Medical Centre, Amsterdam, The Netherlands
    Clin Infect Dis 37:828-30. 2003
    ..We describe a 10-year-old child with vertically transmitted acquired immunodeficiency syndrome who was receiving antiretroviral combination therapy and died of liver failure after beginning voriconazole therapy...
  2. ncbi request reprint Long-term experience with combination antiretroviral therapy that contains nelfinavir for up to 7 years in a pediatric cohort
    Henriette J Scherpbier
    Emma Children s Hospital, Academic Medical Center, Amsterdam, The Netherlands
    Pediatrics 117:e528-36. 2006
    ..We sought to provide long-term data on the clinical, immunologic, and virologic response to highly active antiretroviral therapy in infants and children who are naive to protease inhibitors...
  3. ncbi request reprint Once-daily highly active antiretroviral therapy for HIV-infected children: safety and efficacy of an efavirenz-containing regimen
    Henriette J Scherpbier
    Emma Children s Hospital, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Pediatrics 119:e705-15. 2007
    ....
  4. ncbi request reprint A pharmacokinetic and pharmacogenetic study of efavirenz in children: dosing guidelines can result in subtherapeutic concentrations
    Rob ter Heine
    Department of Pharmacy and Pharmacology, Slotervaart Hospital, Amsterdam, The Netherlands
    Antivir Ther 13:779-87. 2008
    ..Our main objectives were to study the population pharmacokinetics of efavirenz and to explore the adequacy of dosing guidelines...
  5. ncbi request reprint Cytomegalovirus rather than HIV triggers the outgrowth of effector CD8+CD45RA+CD27- T cells in HIV-1-infected children
    Vincent Bekker
    Emma Children s Hospital, Sanquin Research and Landsteiner Laboratory, Academic Medical Center fInternational Antiviral Therapy Evaluation Center, Amsterdam, The Netherlands
    AIDS 19:1025-34. 2005
    ..To analyse the effect of viral coinfections on immune reconstitution in HIV-1-infected children (< 18 years) taking highly active antiretroviral therapy (HAART)...
  6. ncbi request reprint Population pharmacokinetics and pharmacodynamics of nelfinavir and its active metabolite M8 in HIV-1-infected children
    Kristel M L Crommentuyn
    Department of Pharmacy and Pharmacology, Slotervaart Hospital, Amsterdam, The Netherlands
    Pediatr Infect Dis J 25:538-43. 2006
    ....
  7. pmc Neurologic abnormalities in HIV-1 infected children in the era of combination antiretroviral therapy
    Lotus A van Arnhem
    Department of Pediatric Hematology, Immunology and Infectious Diseases, Emma Children s Hospital, Academic Medical Centre AMC, Amsterdam, The Netherlands
    PLoS ONE 8:e64398. 2013
    ..In recent years, the neurological outcome of HIV-1 infected children has substantially improved with combination antiretroviral therapy (cART). However, data regarding the long-term effect of cART and neurologic outcome are limited...
  8. ncbi request reprint Viral dynamics after starting first-line HAART in HIV-1-infected children
    Vincent Bekker
    Emma Children s Hospital, Academic Medical Center, The Netherlands
    AIDS 20:517-23. 2006
    ..Therefore viral decay and time to reach a pVL of < 400 copies/ml during the first weeks after starting HAART were studied in a cohort of HIV-1-infected children...
  9. pmc Long-Term Changes of Subcutaneous Fat Mass in HIV-Infected Children on Antiretroviral Therapy: A Retrospective Analysis of Longitudinal Data from Two Pediatric HIV-Cohorts
    Sophie Cohen
    Department of Paediatric Haematology, Immunology, and Infectious Diseases, Emma Children s Hospital, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    PLoS ONE 10:e0120927. 2015
    ....
  10. ncbi request reprint A neonate with macrosomia, cardiomyopathy and hepatomegaly born to an HIV-infected mother
    Mieke H Godfried
    Department of Internal Medicine, AMC, Amsterdam, The Netherlands
    Eur J Pediatr 164:190-2. 2005
  11. ncbi request reprint The pharmacokinetics of nelfinavir in HIV-1-infected children
    Rolf P G van Heeswijk
    Dept of Pharmacy and Pharmacology, Slotervaart Hospital, Amsterdam, The Netherlands
    Ther Drug Monit 24:487-91. 2002
    ..However, due to a large interpatient variability in the exposure, individual dosage adjustments based on plasma concentrations may be necessary for both dosing regimens to ensure optimal treatment...
  12. ncbi request reprint Haematological parameters of HIV-1-uninfected infants born to HIV-1-infected mothers
    Madeleine J Bunders
    Department of Paediatric Haematology, Immunology and Infectious Diseases, Emma Children s Hospital, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Acta Paediatr 94:1571-7. 2005
    ..To investigate haematological parameters in infants born to HIV-1-infected mothers and exposed to combination antiretroviral therapy (ART) used to prevent mother-to-child transmission (MTCT)...
  13. doi request reprint Cerebral injury in perinatally HIV-infected children compared to matched healthy controls
    Sophie Cohen
    From the Department of Pediatric Hematology, Immunology and Infectious Diseases S C, H J S, T W K, D P, Emma Children s Hospital AMC, Amsterdam the Department of Radiology M W A C, H J M, C B L M M, the Department of Global Health and Amsterdam Institute of Global Health and Development P R, and the Department of Internal Medicine, Division of Infectious Diseases, Center for Infection and Immunity Amsterdam CINIMA P R, Academic Medical Centre, University of Amsterdam and HIV Monitoring Foundation P R, Amsterdam, The Netherlands
    Neurology 86:19-27. 2016
    ..The current study aims to evaluate the neurologic state of perinatally HIV-infected children on combination antiretroviral therapy and to attain a better insight into the pathogenesis of their persistent neurologic and cognitive deficits...
  14. ncbi request reprint Establishment of the CD4+ T-cell pool in healthy children and untreated children infected with HIV-1
    Mette D Hazenberg
    Department of Clinical Viro Immunology, Sanquin Research at CLB, Amsterdam, The Netherlands
    Blood 104:3513-9. 2004
    ..We postulate that in children infected with HIV, similar to adults infected with HIV, continuous activation of naive T cells leads to erosion of the naive T-cell pool and may be a major factor in lowering CD4(+) T-cell numbers...
  15. doi request reprint Health-related quality of life in perinatally HIV-infected children in the Netherlands
    Sophie Cohen
    a Department of Paediatric Hematology, Immunology, and Infectious Diseases, Emma Children s Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    AIDS Care 27:1279-88. 2015
    ..However, the HIV-infected group did contain more children with HRQoL impairment, suggesting that HIV-infected children in the Netherlands are still more vulnerable to a compromised HRQoL. ..
  16. pmc Neurometabolite Alterations Associated With Cognitive Performance in Perinatally HIV-Infected Children
    Yvonne W Van Dalen
    From the Department of Pediatric Hematology, Immunology and Infectious Diseases, YWVD, CB, SC, JATS, HJS, TWK, DP Psychosocial Department JATS, Emma Children s Hospital Academic Medical Center Neurochemistry Laboratory and Biobank CET, Department of Clinical Chemistry, VU University Medical Center and Neurocampus Amsterdam, the Netherlands Neurology JK, Departments of Medicine, Biomedicine and Clinical Research, University Hospital Basel, Basel, Switzerland Department of Experimental Immunology NAK Department of Global Health and Amsterdam Institute of Global Health and Development PR, Academic Medical Center HIV Monitoring Foundation PR Department of Internal Medicine PR, Division of Infectious Diseases, Center for Infection and Immunity Amsterdam CINIMA and Department of Radiology CBLMM, MWAC, Academic Medical Center, Amsterdam, The Netherlands
    Medicine (Baltimore) 95:e3093. 2016
    ..Levels of several neurometabolites were associated with cognitive performance, suggesting that MRS may be a useful method to assess cerebral changes potentially linked to cognitive outcomes. ..
  17. doi request reprint Mannose-binding lectin and the risk of HIV transmission and disease progression in children: a systematic review
    Joël Israëls
    Department of Pediatric Immunology, Hematology and Infectiology, Emma Children s Hospital, Academic Medical Centre, H7 228, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Pediatr Infect Dis J 31:1272-8. 2012
    ..It is unclear whether genetically determined MBL deficiency is related to vertical HIV transmission and disease progression in HIV-infected children...
  18. doi request reprint Bone mineral density increases in HIV-infected children treated with long-term combination antiretroviral therapy
    Madeleine J Bunders
    Department of Paediatric Immunology, Haematology, and Infectious Diseases, Emma Children Hospital, Amsterdam, The Netherlands
    Clin Infect Dis 56:583-6. 2013
    ..Longitudinal data on bone mineral density (BMD) in HIV-infected children showed that cumulative treatment with cART had a positive impact on BMD over time...
  19. doi request reprint Noncirrhotic Portal Hypertension in Perinatally HIV-infected Adolescents Treated With Didanosine-containing Antiretroviral Regimens in Childhood
    Henriette J Scherpbier
    From the Department of Pediatric Hematology, Immunology and Infectious Diseases, and Department of Pathology, Emma Children s Hospital, Academic Medical Center AMC, Amsterdam, The Netherlands Department of Pathology, MCH Bronovo Hospital, The Hague, The Netherlands Faculty of Medicine, Chulalongkorn University and HIVNAT, Thai Red Cross AIDS Research Center, Bangkok, Thailand U S Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, and Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, Department of Infectious Diseases, Imperial College Healthcare NHS Trust, London, United Kingdom Department of Radiodiagnostics and Infectious Diseases, AMC and Department of Pediatric Gastroenterology, Emma Children s Hospital, AMC, Amsterdam, The Netherlands
    Pediatr Infect Dis J 35:e248-52. 2016
    ..Noncirrhotic portal hypertension (NCPH) has been reported in HIV-infected adults. Antiretroviral drugs, as well as genetic and thrombophilic predisposition, have been suggested as possible etiologic factors...
  20. doi request reprint Country of birth does not influence long-term clinical, virologic, and immunological outcome of HIV-infected children living in the Netherlands: a cohort study comparing children born in the Netherlands with children born in Sub-Saharan Africa
    Sophie Cohen
    Department of Pediatric Haematology, Immunology and Infectious Diseases, Emma Children s Hospital, Academic Medical Center, Amsterdam, the Netherlands Dutch HIV Monitoring Foundation, Amsterdam, The Netherlands Department of Pediatrics, Division of Infectious Diseases, Immunology and Rheumatology, Erasmus MC University Hospital Rotterdam Sophia Children s Hospital, Rotterdam, the Netherlands Erasmus MC Viroscience Lab, Erasmus MC, Rotterdam, the Netherlands The Nijmegen Institute for Infection, Inflammation and Immunity, Radboud University Medical Center, Nijmegen, the Netherlands and Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children s Hospital University Medical Center, Utrecht, The Netherlands
    J Acquir Immune Defic Syndr 68:178-85. 2015
    ..We aimed to investigate potential differences in clinical, immunological, and virologic outcome in Dutch HIV-infected children born in the Netherlands (NL) versus born in Sub-Saharan Africa (SSA) in a national cohort analysis...