Dasja Pajkrt

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. pmc Inadequate vancomycin therapy in term and preterm neonates: a retrospective analysis of trough serum concentrations in relation to minimal inhibitory concentrations
    Fleur S Sinkeler
    Academic Medical Center Department of Clinical Pharmacy, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    BMC Pediatr 14:193. 2014
  2. ncbi request reprint Pyelonephritis caused by Actinobaculum schaalii in a child with pyeloureteral junction obstruction
    D Pajkrt
    Department of Paediatrics, Academic Medical Center, Meibergdreef 9, 1005 AZ Amsterdam, The Netherlands
    Eur J Clin Microbiol Infect Dis 22:438-40. 2003
  3. doi request reprint Clinical characteristics of human parechoviruses 4-6 infections in young children
    Dasja Pajkrt
    Department of Pediatric Infectious Diseases, Emma Children s Hospital, Amsterdam, The Netherlands
    Pediatr Infect Dis J 28:1008-10. 2009
  4. ncbi request reprint Once-daily highly active antiretroviral therapy for HIV-infected children: safety and efficacy of an efavirenz-containing regimen
    Henriette J Scherpbier
    Emma Children s Hospital, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Pediatrics 119:e705-15. 2007
  5. pmc Long-Term Changes of Subcutaneous Fat Mass in HIV-Infected Children on Antiretroviral Therapy: A Retrospective Analysis of Longitudinal Data from Two Pediatric HIV-Cohorts
    Sophie Cohen
    Department of Paediatric Haematology, Immunology, and Infectious Diseases, Emma Children s Hospital, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    PLoS ONE 10:e0120927. 2015
  6. pmc Neurologic abnormalities in HIV-1 infected children in the era of combination antiretroviral therapy
    Lotus A van Arnhem
    Department of Pediatric Hematology, Immunology and Infectious Diseases, Emma Children s Hospital, Academic Medical Centre AMC, Amsterdam, The Netherlands
    PLoS ONE 8:e64398. 2013
  7. doi request reprint Specific cell tropism and neutralization of human parechovirus types 1 and 3: implications for pathogenesis and therapy development
    Brenda M Westerhuis
    Laboratory of Clinical Virology, Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands
    J Gen Virol 93:2363-70. 2012
  8. doi request reprint Cerebral injury in perinatally HIV-infected children compared to matched healthy controls
    Sophie Cohen
    From the Department of Pediatric Hematology, Immunology and Infectious Diseases S C, H J S, T W K, D P, Emma Children s Hospital AMC, Amsterdam the Department of Radiology M W A C, H J M, C B L M M, the Department of Global Health and Amsterdam Institute of Global Health and Development P R, and the Department of Internal Medicine, Division of Infectious Diseases, Center for Infection and Immunity Amsterdam CINIMA P R, Academic Medical Centre, University of Amsterdam and HIV Monitoring Foundation P R, Amsterdam, The Netherlands
    Neurology 86:19-27. 2016
  9. doi request reprint Clinical, virological and epidemiological characteristics of rhinovirus infections in early childhood: A comparison between non-hospitalised and hospitalised children
    Andrea H L Bruning
    Department of Pediatric Infectious Diseases, Emma Children s Hospital, Academic Medical Center, Amsterdam, The Netherlands Electronic address
    J Clin Virol 73:120-6. 2015
  10. doi request reprint Health-related quality of life in perinatally HIV-infected children in the Netherlands
    Sophie Cohen
    a Department of Paediatric Hematology, Immunology, and Infectious Diseases, Emma Children s Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    AIDS Care 27:1279-88. 2015

Collaborators

Detail Information

Publications33

  1. pmc Inadequate vancomycin therapy in term and preterm neonates: a retrospective analysis of trough serum concentrations in relation to minimal inhibitory concentrations
    Fleur S Sinkeler
    Academic Medical Center Department of Clinical Pharmacy, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    BMC Pediatr 14:193. 2014
    ....
  2. ncbi request reprint Pyelonephritis caused by Actinobaculum schaalii in a child with pyeloureteral junction obstruction
    D Pajkrt
    Department of Paediatrics, Academic Medical Center, Meibergdreef 9, 1005 AZ Amsterdam, The Netherlands
    Eur J Clin Microbiol Infect Dis 22:438-40. 2003
    ..Pyelonephritis or any other urinary tract infection caused by Actinobaculum schaalii has not been described in children before. The patient responded well to pyeloplasty in combination with antibiotic treatment...
  3. doi request reprint Clinical characteristics of human parechoviruses 4-6 infections in young children
    Dasja Pajkrt
    Department of Pediatric Infectious Diseases, Emma Children s Hospital, Amsterdam, The Netherlands
    Pediatr Infect Dis J 28:1008-10. 2009
    ..HPeV1 and 2 have been associated with mild gastrointestinal or respiratory symptoms in young children. HPeV3 is associated with more severe neonatal infection. Little is known about the epidemiology and pathology of HPeV4-6 in children...
  4. ncbi request reprint Once-daily highly active antiretroviral therapy for HIV-infected children: safety and efficacy of an efavirenz-containing regimen
    Henriette J Scherpbier
    Emma Children s Hospital, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Pediatrics 119:e705-15. 2007
    ....
  5. pmc Long-Term Changes of Subcutaneous Fat Mass in HIV-Infected Children on Antiretroviral Therapy: A Retrospective Analysis of Longitudinal Data from Two Pediatric HIV-Cohorts
    Sophie Cohen
    Department of Paediatric Haematology, Immunology, and Infectious Diseases, Emma Children s Hospital, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    PLoS ONE 10:e0120927. 2015
    ....
  6. pmc Neurologic abnormalities in HIV-1 infected children in the era of combination antiretroviral therapy
    Lotus A van Arnhem
    Department of Pediatric Hematology, Immunology and Infectious Diseases, Emma Children s Hospital, Academic Medical Centre AMC, Amsterdam, The Netherlands
    PLoS ONE 8:e64398. 2013
    ..In recent years, the neurological outcome of HIV-1 infected children has substantially improved with combination antiretroviral therapy (cART). However, data regarding the long-term effect of cART and neurologic outcome are limited...
  7. doi request reprint Specific cell tropism and neutralization of human parechovirus types 1 and 3: implications for pathogenesis and therapy development
    Brenda M Westerhuis
    Laboratory of Clinical Virology, Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands
    J Gen Virol 93:2363-70. 2012
    ....
  8. doi request reprint Cerebral injury in perinatally HIV-infected children compared to matched healthy controls
    Sophie Cohen
    From the Department of Pediatric Hematology, Immunology and Infectious Diseases S C, H J S, T W K, D P, Emma Children s Hospital AMC, Amsterdam the Department of Radiology M W A C, H J M, C B L M M, the Department of Global Health and Amsterdam Institute of Global Health and Development P R, and the Department of Internal Medicine, Division of Infectious Diseases, Center for Infection and Immunity Amsterdam CINIMA P R, Academic Medical Centre, University of Amsterdam and HIV Monitoring Foundation P R, Amsterdam, The Netherlands
    Neurology 86:19-27. 2016
    ..The current study aims to evaluate the neurologic state of perinatally HIV-infected children on combination antiretroviral therapy and to attain a better insight into the pathogenesis of their persistent neurologic and cognitive deficits...
  9. doi request reprint Clinical, virological and epidemiological characteristics of rhinovirus infections in early childhood: A comparison between non-hospitalised and hospitalised children
    Andrea H L Bruning
    Department of Pediatric Infectious Diseases, Emma Children s Hospital, Academic Medical Center, Amsterdam, The Netherlands Electronic address
    J Clin Virol 73:120-6. 2015
    ....
  10. doi request reprint Health-related quality of life in perinatally HIV-infected children in the Netherlands
    Sophie Cohen
    a Department of Paediatric Hematology, Immunology, and Infectious Diseases, Emma Children s Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    AIDS Care 27:1279-88. 2015
    ..However, the HIV-infected group did contain more children with HRQoL impairment, suggesting that HIV-infected children in the Netherlands are still more vulnerable to a compromised HRQoL. ..
  11. pmc Neurometabolite Alterations Associated With Cognitive Performance in Perinatally HIV-Infected Children
    Yvonne W Van Dalen
    From the Department of Pediatric Hematology, Immunology and Infectious Diseases, YWVD, CB, SC, JATS, HJS, TWK, DP Psychosocial Department JATS, Emma Children s Hospital Academic Medical Center Neurochemistry Laboratory and Biobank CET, Department of Clinical Chemistry, VU University Medical Center and Neurocampus Amsterdam, the Netherlands Neurology JK, Departments of Medicine, Biomedicine and Clinical Research, University Hospital Basel, Basel, Switzerland Department of Experimental Immunology NAK Department of Global Health and Amsterdam Institute of Global Health and Development PR, Academic Medical Center HIV Monitoring Foundation PR Department of Internal Medicine PR, Division of Infectious Diseases, Center for Infection and Immunity Amsterdam CINIMA and Department of Radiology CBLMM, MWAC, Academic Medical Center, Amsterdam, The Netherlands
    Medicine (Baltimore) 95:e3093. 2016
    ..Levels of several neurometabolites were associated with cognitive performance, suggesting that MRS may be a useful method to assess cerebral changes potentially linked to cognitive outcomes. ..
  12. doi request reprint Development and evaluation of a four-tube real time multiplex PCR assay covering fourteen respiratory viruses, and comparison to its corresponding single target counterparts
    Rogier R Jansen
    Laboratory of Clinical Virology, Department of Medical Microbiology, Academic Medical Centre, University of Amsterdam, PO Box 22600, 1100 DD, Amsterdam, The Netherlands
    J Clin Virol 51:179-85. 2011
    ..However, comprehensive data on sensitivity, specificity and performance of the multiplex PCR compared to the single target PCR's is limited for most published respiratory multiplex real time PCR assays...
  13. doi request reprint Human parechoviruses as an important viral cause of sepsislike illness and meningitis in young children
    Katja C Wolthers
    Department of Medical Microbiology, Laboratory of Clinical Virology, Emma Children s Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Clin Infect Dis 47:358-63. 2008
    ..Six HPeV genotypes are currently known, of which HPeV3 is associated with neonatal sepsis and meningitis...
  14. doi request reprint Successful IVIG treatment of human parechovirus-associated dilated cardiomyopathy in an infant
    Joanne G Wildenbeest
    Department of Pediatric Infectious Diseases and Immunology, Emma Children s Hospital, Academic Medical Center, Amsterdam, The Netherlands
    Pediatrics 132:e243-7. 2013
    ..More research combining virological and clinical data is needed to see whether this hypothesis is true. ..
  15. doi request reprint The need for treatment against human parechoviruses: how, why and when?
    Joanne G Wildenbeest
    Department of Medical Microbiology, Laboratory of Clinical Virology, K1 121, Academic Medical Center, Meibergdreef 15, 1105 AZ, Amsterdam, The Netherlands
    Expert Rev Anti Infect Ther 8:1417-29. 2010
    ....
  16. doi request reprint Quantitation of respiratory viruses in relation to clinical course in children with acute respiratory tract infections
    Rogier R Jansen
    Department of Medical Microbiology, Academical Medical Centre, University of Amsterdam, Room L1 245, Meibergdreef 9, 1105 AZ Amsterdam, TheNetherlands
    Pediatr Infect Dis J 29:82-4. 2010
    ..Clinical improvement was associated with reduction of viral quantity after 3 days of hospitalization...
  17. doi request reprint Multiple-azole-resistant Aspergillus fumigatus osteomyelitis in a patient with chronic granulomatous disease successfully treated with long-term oral posaconazole and surgery
    Caspar J Hodiamont
    Department of Medical Microbiology, Academic Medical Center, Amsterdam
    Med Mycol 47:217-20. 2009
    ..He made a complete recovery and did not experience any side effects. Long-term posaconazole proved to be a safe and effective treatment for multi-azole resistant A. fumigatus osteomyelitis in this immunocompromised patient...
  18. ncbi request reprint Alterations in lipoprotein homeostasis during human experimental endotoxemia and clinical sepsis
    Johannes H M Levels
    Department of Experimental Vascular Medicine, University of Amsterdam, Amsterdam, The Netherlands
    Biochim Biophys Acta 1771:1429-38. 2007
    ..This may be explained, at least in part, by the fact that PLTP as a positive acute phase protein, can accelerate the alterations in (phospho)lipid homeostasis thereby playing a role in the attenuation of the acute phase response...
  19. ncbi request reprint Monocyte-derived dendritic cells from chronic HCV patients are not infected but show an immature phenotype and aberrant cytokine profile
    Huub C Gelderblom
    Department of Gastroenterology and Hepatology, AMC Liver Center, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Liver Int 27:944-53. 2007
    ..Therefore, we studied the presence of HCV RNA in monocytes and monocyte-derived DCs from chronic HCV patients...
  20. doi request reprint Prolonged Shedding of Human Parechovirus in Feces of Young Children after Symptomatic Infection
    Joanne G Wildenbeest
    From the Department of Pediatric Infectious Diseases and Immunology, Emma Children s Hospital, Academic Medical Center AMC, Amsterdam, The Netherlands Laboratory of Clinical Virology, Department of Medical Microbiology, AMC, Amsterdam, The Netherlands Department of Pediatrics, Amstelland Hospital, Amsterdam, The Netherlands
    Pediatr Infect Dis J 35:580-3. 2016
    ....
  21. doi request reprint Virological and Social Outcomes of HIV-Infected Adolescents and Young Adults in The Netherlands Before and After Transition to Adult Care
    Annouschka M Weijsenfeld
    Department of Pediatric Infectious Diseases, Emma Children s Hospital, Academic Medical Centre AMC
    Clin Infect Dis 63:1105-12. 2016
    ..We aimed to evaluate virological and social outcomes of HIV-infected adolescents and young adults (AYAs) before and after transition, and explore which factors are associated with virological failure...
  22. doi request reprint Retinal Structure and Function in Perinatally HIV-Infected and cART-Treated Children: A Matched Case-Control Study
    Nazli Demirkaya
    Department of Ophthalmology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Invest Ophthalmol Vis Sci 56:3945-54. 2015
    ..This study aimed to assess the presence of (neuro)retinal functional and structural differences between a group of perinatally HIV-infected children on cART and age-, sex-, ethnicity-, and socioeconomically matched healthy controls...
  23. doi request reprint Noncirrhotic Portal Hypertension in Perinatally HIV-infected Adolescents Treated With Didanosine-containing Antiretroviral Regimens in Childhood
    Henriette J Scherpbier
    From the Department of Pediatric Hematology, Immunology and Infectious Diseases, and Department of Pathology, Emma Children s Hospital, Academic Medical Center AMC, Amsterdam, The Netherlands Department of Pathology, MCH Bronovo Hospital, The Hague, The Netherlands Faculty of Medicine, Chulalongkorn University and HIVNAT, Thai Red Cross AIDS Research Center, Bangkok, Thailand U S Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, and Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, Department of Infectious Diseases, Imperial College Healthcare NHS Trust, London, United Kingdom Department of Radiodiagnostics and Infectious Diseases, AMC and Department of Pediatric Gastroenterology, Emma Children s Hospital, AMC, Amsterdam, The Netherlands
    Pediatr Infect Dis J 35:e248-52. 2016
    ..Noncirrhotic portal hypertension (NCPH) has been reported in HIV-infected adults. Antiretroviral drugs, as well as genetic and thrombophilic predisposition, have been suggested as possible etiologic factors...
  24. doi request reprint Bone mineral density increases in HIV-infected children treated with long-term combination antiretroviral therapy
    Madeleine J Bunders
    Department of Paediatric Immunology, Haematology, and Infectious Diseases, Emma Children Hospital, Amsterdam, The Netherlands
    Clin Infect Dis 56:583-6. 2013
    ..Longitudinal data on bone mineral density (BMD) in HIV-infected children showed that cumulative treatment with cART had a positive impact on BMD over time...
  25. pmc Neonatal gram negative and Candida sepsis survival and neurodevelopmental outcome at the corrected age of 24 months
    Timo R de Haan
    Department of Neonatology, Emma Children s Hospital, Academic Medical Center Amsterdam, The Netherlands
    PLoS ONE 8:e59214. 2013
    ..To evaluate the long term neurodevelopmental outcome of premature infants exposed to either gram- negative sepsis (GNS) or neonatal Candida sepsis (NCS), and to compare their outcome with premature infants without sepsis...
  26. ncbi request reprint Persistent humoral immune defect in highly active antiretroviral therapy-treated children with HIV-1 infection: loss of specific antibodies against attenuated vaccine strains and natural viral infection
    Vincent Bekker
    Emma Children s Hospital, Academic Medical Center, Room G8 205, Meibergdreef 9, 1105 AZ Amsterdam, Netherlands
    Pediatrics 118:e315-22. 2006
    ..In the pre-highly active antiretroviral therapy era, a loss of specific antibodies was seen. Our objective with this study was to describe the loss of specific antibodies during treatment with highly active antiretroviral therapy...
  27. doi request reprint Neonate with Mycoplasma hominis meningoencephalitis given moxifloxacin
    Joanne G Wildenbeest
    Department of Paediatric Haematology, Immunology and Infectious Diseases, Emma Children s Hospital, Academic Medical Center, Amsterdam, Netherlands Department of Paediatrics, Onze Lieve Vrouwe Gasthuis, Amsterdam, Netherlands Electronic address
    Lancet Infect Dis 16:e261-e266. 2016
    ....
  28. doi request reprint Human immunodeficiency virus type 1 gp120 envelope characteristics associated with disease progression differ in family members infected with genetically similar viruses
    Elly Baan
    Laboratory of Experimental Virology LEV, Department of Medical Microbiology, Center for Infection and Immunity Amsterdam CINIMA, Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands
    J Gen Virol 94:20-9. 2013
    ....
  29. doi request reprint Country of birth does not influence long-term clinical, virologic, and immunological outcome of HIV-infected children living in the Netherlands: a cohort study comparing children born in the Netherlands with children born in Sub-Saharan Africa
    Sophie Cohen
    Department of Pediatric Haematology, Immunology and Infectious Diseases, Emma Children s Hospital, Academic Medical Center, Amsterdam, the Netherlands Dutch HIV Monitoring Foundation, Amsterdam, The Netherlands Department of Pediatrics, Division of Infectious Diseases, Immunology and Rheumatology, Erasmus MC University Hospital Rotterdam Sophia Children s Hospital, Rotterdam, the Netherlands Erasmus MC Viroscience Lab, Erasmus MC, Rotterdam, the Netherlands The Nijmegen Institute for Infection, Inflammation and Immunity, Radboud University Medical Center, Nijmegen, the Netherlands and Department of Pediatric Infectious Diseases and Immunology, Wilhelmina Children s Hospital University Medical Center, Utrecht, The Netherlands
    J Acquir Immune Defic Syndr 68:178-85. 2015
    ..We aimed to investigate potential differences in clinical, immunological, and virologic outcome in Dutch HIV-infected children born in the Netherlands (NL) versus born in Sub-Saharan Africa (SSA) in a national cohort analysis...
  30. doi request reprint An atypical course of coxsackievirus A6 associated hand, foot and mouth disease in extremely low birth weight preterm twins
    Andrea H L Bruning
    Department of Pediatric Infectious Diseases, Emma Children s Hospital, Academic Medical Center, Amsterdam, The Netherlands Electronic address
    J Clin Virol 65:20-2. 2015
    ..We here describe an atypical course of CV-A6-associated HFMD in extremely low birth weight twins. The CV-A6-strains are genetically closely related to international strains isolated from HFMD outbreaks. ..
  31. doi request reprint The effect of different intervention programs on treatment adherence of HIV-infected children, a retrospective study
    Atie van der Plas
    Academic Medical Centre, Department of Paediatric Infectious Diseases, Emma Children s Hospital, Amsterdam, The Netherlands
    AIDS Care 25:738-43. 2013
    ..Further prospective studies are needed to evaluate the long-term effect of this new treatment intervention program...
  32. pmc Effect of HIV and chlamydia infection on rectal inflammation and cytokine concentrations in men who have sex with men
    Marlies Heiligenberg
    Cluster of Infectious Diseases, Health Service Amsterdam, Amsterdam, The Netherlands
    Clin Vaccine Immunol 20:1517-23. 2013
    ..The extent of mucosal damage was comparable in all patient groups. The apparent reduced neutrophil response to IL-8 in HIV-infected patients with C. trachomatis infection is in accordance with its asymptomatic course. ..
  33. ncbi request reprint Diagnosis and treatment of cutaneous zygomycosis
    Douwe H Visser
    Department of Pediatric Surgery, VU University Medical Center, Amsterdam, The Netherlands
    Pediatr Infect Dis J 26:1165-6. 2007
    ..We present case reports of 2 patients...