Mark J Geels
Affiliation: Academic Medical Center
Country: The Netherlands
- CTL escape and increased viremia irrespective of HIV-specific CD4+ T-helper responses in two HIV-infected individualsMark J Geels
Department of Human Retrovirology, Academic Medical Centre, University of Amsterdam, The Netherlands
Virology 345:209-19. 2006..This suggests that loss of T-cell reactivity may not be directly linked to HIV-specific CD4(+) T-cell responses but that increased viremia after CTL escape may influence CD4(+) T-helper responses...
- Broad cross-clade T-cell responses to gag in individuals infected with human immunodeficiency virus type 1 non-B clades (A to G): importance of HLA anchor residue conservationMark J Geels
Department of Human Retrovirology, Academisch Medisch Centrum, Amsterdam, The Netherlands
J Virol 79:11247-58. 2005....
- Identification of sequential viral escape mutants associated with altered T-cell responses in a human immunodeficiency virus type 1-infected individualMark J Geels
Department of Human Retrovirology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
J Virol 77:12430-40. 2003..These results demonstrate the sequential accumulation of CTL escape in a patient during disease progression, indicating that multiple combinations of T-cell epitopes are required to control viremia...
- Varied sensitivity to therapy of HIV-1 strains in CD4+ lymphocyte sub-populations upon ART initiationEdwin J Heeregrave
Laboratory of Experimental Virology, Department of Medical Microbiology, Center of Infection and Immunity Amsterdam CINIMA, Academic Medical Center of the University of Amsterdam, The Netherlands
AIDS Res Ther 7:42. 2010..In this study we analyzed the sensitivity to ART of HIV-1 strains in naïve, central memory and effector memory CD4+ lymphocyte subsets...