Marion Cornelissen

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. pmc Gene expression profile of AIDS-related Kaposi's sarcoma
    Marion Cornelissen
    Department of Human Retrovirology, Academic Medical Centre, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands
    BMC Cancer 3:7. 2003
  2. pmc Highly sensitive methods based on seminested real-time reverse transcription-PCR for quantitation of human immunodeficiency virus type 1 unspliced and multiply spliced RNA and proviral DNA
    Alexander O Pasternak
    Department of Medical Microbiology, Laboratory of Experimental Virology, Center for Infection and Immunity Amsterdam, Academic Medical Center, University of Amsterdam, Meibergdreef 15, Amsterdam 1105 AZ, The Netherlands
    J Clin Microbiol 46:2206-11. 2008
  3. pmc Analysis of infectious virus clones from two HIV-1 superinfection cases suggests that the primary strains have lower fitness
    Antoinette C van der Kuyl
    Laboratory of Experimental Virology, Department of Medical Microbiology, Centre for Infection and Immunity Amsterdam CINIMA, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Retrovirology 7:60. 2010
  4. ncbi request reprint Cytomegalovirus and human herpesvirus 8 DNA detection in peripheral blood monocytic cells of AIDS patients: correlations with the presence of Kaposi's sarcoma and CMV disease
    Antoinette C van der Kuyl
    Department of Human Retrovirology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Med Virol 76:541-6. 2005
  5. pmc Severe anaemia is not associated with HIV-1 env gene characteristics in Malawian children
    Job C J Calis
    Emma Children s Hospital, Academic Medical Centre, Amsterdam, The Netherlands
    BMC Infect Dis 8:26. 2008
  6. pmc Generation of representative primary virus isolates from blood plasma after isolation of HIV-1 with CD44 MicroBeads
    Marion Cornelissen
    Laboratory of Experimental Virology, Department of Medical Microbiology, Centre of Infection and Immunity Amsterdam CINIMA, Academic Medical Centre of the University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands
    Arch Virol 155:2017-22. 2010
  7. ncbi request reprint Routine HIV-1 genotyping as a tool to identify dual infections
    Marion Cornelissen
    Laboratory of Experimental Virology, Department of Medical Microbiology, Centre for Infection and Immunity Amsterdam, Academic Medical Centre of the University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands
    AIDS 21:807-11. 2007
  8. ncbi request reprint Retrospective, longitudinal analysis of serum human herpesvirus-8 viral DNA load in AIDS-related Kaposi's sarcoma patients before and after diagnosis
    Abeltje M Polstra
    Department of Human Retrovirology, Academic Medical Centre, University of Amsterdam, Meibergdreef, Amsterdam, The Netherlands
    J Med Virol 74:390-6. 2004
  9. ncbi request reprint An IL-8 gene promoter polymorphism is associated with the risk of the development of AIDS-related Kaposi's sarcoma: a case-control study
    Antoinette C van der Kuyl
    Department of Human Retrovirology, Academic Medical Centre, University of Amsterdam, The Netherlands
    AIDS 18:1206-8. 2004
  10. pmc Primary effect of chemotherapy on the transcription profile of AIDS-related Kaposi's sarcoma
    Antoinette C van der Kuyl
    Department of Human Retrovirology, Academic Medical Center, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands
    BMC Cancer 2:21. 2002

Detail Information

Publications30

  1. pmc Gene expression profile of AIDS-related Kaposi's sarcoma
    Marion Cornelissen
    Department of Human Retrovirology, Academic Medical Centre, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands
    BMC Cancer 3:7. 2003
    ..Its course is aggravated by co-infection with HIV-1, where the timing of infection with HIV-1 and HHV8 is important for the clinical outcome...
  2. pmc Highly sensitive methods based on seminested real-time reverse transcription-PCR for quantitation of human immunodeficiency virus type 1 unspliced and multiply spliced RNA and proviral DNA
    Alexander O Pasternak
    Department of Medical Microbiology, Laboratory of Experimental Virology, Center for Infection and Immunity Amsterdam, Academic Medical Center, University of Amsterdam, Meibergdreef 15, Amsterdam 1105 AZ, The Netherlands
    J Clin Microbiol 46:2206-11. 2008
    ..These easy-to-perform methods can be widely used in research, including clinical studies, to monitor intracellular processes of virus replication...
  3. pmc Analysis of infectious virus clones from two HIV-1 superinfection cases suggests that the primary strains have lower fitness
    Antoinette C van der Kuyl
    Laboratory of Experimental Virology, Department of Medical Microbiology, Centre for Infection and Immunity Amsterdam CINIMA, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Retrovirology 7:60. 2010
    ..The use of isolate-specific primer sets indicated that the primary and secondary strains co-exist in plasma at all time points after the moment of superinfection...
  4. ncbi request reprint Cytomegalovirus and human herpesvirus 8 DNA detection in peripheral blood monocytic cells of AIDS patients: correlations with the presence of Kaposi's sarcoma and CMV disease
    Antoinette C van der Kuyl
    Department of Human Retrovirology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Med Virol 76:541-6. 2005
    ..Therefore, HHV8 and CMV DNA measured in the blood of AIDS patients, are each related mainly to the associated disease, and have no additional predictive value in these patients...
  5. pmc Severe anaemia is not associated with HIV-1 env gene characteristics in Malawian children
    Job C J Calis
    Emma Children s Hospital, Academic Medical Centre, Amsterdam, The Netherlands
    BMC Infect Dis 8:26. 2008
    ..We therefore explored the possibility that alterations in the V1-V2-V3 fragment of HIV-1 were associated with severe anaemia...
  6. pmc Generation of representative primary virus isolates from blood plasma after isolation of HIV-1 with CD44 MicroBeads
    Marion Cornelissen
    Laboratory of Experimental Virology, Department of Medical Microbiology, Centre of Infection and Immunity Amsterdam CINIMA, Academic Medical Centre of the University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands
    Arch Virol 155:2017-22. 2010
    ..CCR5 cultures. Therefore, isolation of primary viruses with CD44 MicroBeads results in a good representation in cell culture of the in vivo divergence...
  7. ncbi request reprint Routine HIV-1 genotyping as a tool to identify dual infections
    Marion Cornelissen
    Laboratory of Experimental Virology, Department of Medical Microbiology, Centre for Infection and Immunity Amsterdam, Academic Medical Centre of the University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands
    AIDS 21:807-11. 2007
    ..Methods to identify HIV-1 dual infections are time consuming and are not routinely performed...
  8. ncbi request reprint Retrospective, longitudinal analysis of serum human herpesvirus-8 viral DNA load in AIDS-related Kaposi's sarcoma patients before and after diagnosis
    Abeltje M Polstra
    Department of Human Retrovirology, Academic Medical Centre, University of Amsterdam, Meibergdreef, Amsterdam, The Netherlands
    J Med Virol 74:390-6. 2004
    ..Longitudinal serum samples from 19 AIDS-Kaposi's sarcoma patients, ranging from 2 years before KS till 2 years after KS diagnosis were tested. No correlation was found between viral load and progression to KS, or disease stage...
  9. ncbi request reprint An IL-8 gene promoter polymorphism is associated with the risk of the development of AIDS-related Kaposi's sarcoma: a case-control study
    Antoinette C van der Kuyl
    Department of Human Retrovirology, Academic Medical Centre, University of Amsterdam, The Netherlands
    AIDS 18:1206-8. 2004
    ..038). Patients with TT genotype were rarely affected with visceral KS (7% versus 36%; P=0.06), which suggests that carriers of the TT genotype are protected from (severe) KS development...
  10. pmc Primary effect of chemotherapy on the transcription profile of AIDS-related Kaposi's sarcoma
    Antoinette C van der Kuyl
    Department of Human Retrovirology, Academic Medical Center, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands
    BMC Cancer 2:21. 2002
    ..From in vitro studies it has become clear that these drugs can affect specific genes, as well as have an effect upon the total transcriptome...
  11. pmc Identification of sequential viral escape mutants associated with altered T-cell responses in a human immunodeficiency virus type 1-infected individual
    Mark J Geels
    Department of Human Retrovirology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Virol 77:12430-40. 2003
    ..These results demonstrate the sequential accumulation of CTL escape in a patient during disease progression, indicating that multiple combinations of T-cell epitopes are required to control viremia...
  12. ncbi request reprint Combination antiretroviral therapy failure and HIV super-infection
    Daniela Bezemer
    HIV Monitoring Foundation, Academic Medical Centre, University of Amsterdam, The Netherlands
    AIDS 22:309-11. 2008
    ..We analysed HIV pol genes obtained before start of initially successful cART and during failure while still on cART in 101 patients. Difference in precART and cART failure sequences were explained by evolution and not by super-infection...
  13. doi request reprint Quantitation of HIV-1 DNA with a sensitive TaqMan assay that has broad subtype specificity
    Renee M van der Sluis
    Laboratory of Experimental Virology, Department of Medical Microbiology, Centre for Infection and Immunity Amsterdam, Academic Medical Centre, University of Amsterdam, Meibergdreef 15, Amsterdam, The Netherlands
    J Virol Methods 187:94-102. 2013
    ..Execution of the pre-amplification step with a second primer set enables for the exclusive quantitation of the 2-LTR circular HIV-1 DNA form...
  14. ncbi request reprint Latent and lytic HHV-8 mRNA expression in PBMCs and Kaposi's sarcoma skin biopsies of AIDS Kaposi's sarcoma patients
    Abeltje M Polstra
    Department of Human Retrovirology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Med Virol 70:624-7. 2003
    ..Thus, the HHV-8 DNA load in the PBMCs increases in more advanced Kaposi's sarcoma, as does the frequency of mRNA detection in PBMCs...
  15. pmc Widespread hepatitis B virus genotype G (HBV-G) infection during the early years of the HIV epidemic in the Netherlands among men who have sex with men
    Marion Cornelissen
    Laboratory of Experimental Virology, Department of Medical Microbiology, Center for Infection and Immunity Amsterdam CINIMA, Academic Medical Center of the University of Amsterdam, Meibergdreef 15, 1105 AZ, Amsterdam, The Netherlands
    BMC Infect Dis 16:268. 2016
    ..The origin and epidemiology of HBV-G remain unresolved, as is the disease association...
  16. doi request reprint From clinical sample to complete genome: Comparing methods for the extraction of HIV-1 RNA for high-throughput deep sequencing
    Marion Cornelissen
    Laboratory of Experimental Virology, Department of Medical Microbiology, Center for Infection and Immunity Amsterdam CINIMA, Academic Medical Center of the University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands
    Virus Res . 2016
    ..A plasma viral load of >100,000 copies/ml resulted in successful amplification of all four amplicons for 86% of the samples, this value dropped to only 46% for samples with viral loads of <20,000 copies/ml...
  17. pmc Absence of seroreversion in 80 HAART-treated HIV-1 seropositive patients with at least five-years undetectable plasma HIV-1 viral load
    Marion Cornelissen
    Department of Human Retrovirology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    AIDS Res Ther 3:3. 2006
    ..So, successful HAART treatment during chronic HIV-1 infection does not induce seroreversion...
  18. pmc A human immunodeficiency virus type 1-infected individual with low viral load harbors a virus variant that exhibits an in vitro RNA dimerization defect
    Hendrik Huthoff
    Department of Human Retrovirology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Virol 78:4907-13. 2004
    ....
  19. pmc Sialoadhesin (CD169) expression in CD14+ cells is upregulated early after HIV-1 infection and increases during disease progression
    Antoinette C van der Kuyl
    Laboratory of Experimental Virology, Department of Medical Microbiology, Centre for Infection and Immunity Amsterdam CINIMA, Academic Medical Centre of the University of Amsterdam, Amsterdam, The Netherlands
    PLoS ONE 2:e257. 2007
    ..CD169 is highly expressed by macrophages present in AIDS-related Kaposi's sarcoma lesions. It is also increased on blood monocytes of HIV-1 infected patients with a high viral load despite antiretroviral treatment...
  20. ncbi request reprint Antiviral activity of HIV type 1 protease inhibitors nelfinavir and indinavir in vivo is not influenced by P-glycoprotein activity on CD4+ T cells
    Sanjay U C Sankatsing
    International Antiviral Therapy Evaluation Center, Amsterdam, The Netherlands
    AIDS Res Hum Retroviruses 23:19-27. 2007
    ..Therefore we conclude that the potential efflux function of P-gp on PIs may be clinically less relevant than the effect of P-gp on intracellular HIV-1 replication...
  21. pmc HIV-1 sequence evolution in vivo after superinfection with three viral strains
    Karolina Kozaczynska
    Laboratory of Experimental Virology, Department of Medical Microbiology, Centre for Infection and Immunity Amsterdam CINIMA, Academic Medical Centre of the University of Amsterdam, Amsterdam, The Netherlands
    Retrovirology 4:59. 2007
    ..All three strains were detected in seminal plasma, suggesting that simultaneous transmission is possible...
  22. pmc Human herpesvirus 8 load in matched serum and plasma samples of patients with AIDS-associated Kaposi's sarcoma
    Abeltje M Polstra
    Department of Human Retrovirology University of Amsterdam, The Netherlands
    J Clin Microbiol 41:5488-91. 2003
    ..Therefore, our results suggest that serum is the preferred material for HHV-8 load testing, since there is less possible hindrance in the amplification than with plasma...
  23. pmc Identifying HIV-1 dual infections
    Antoinette C van der Kuyl
    Laboratory of Experimental Virology, Department of Medical Microbiology, Centre for Infection and Immunity Amsterdam CINIMA, Academic Medical Centre of the University of Amsterdam, Amsterdam, The Netherlands
    Retrovirology 4:67. 2007
    ..The identification of a source partner would of course confirm the authenticity of the second infection...
  24. doi request reprint Incidence of human immunodeficiency virus type 1 dual infections in Amsterdam, The Netherlands, during 2003-2007
    Antoinette C van der Kuyl
    Department of Medical Microbiology, Laboratory of Experimental Virology, Center for Infection and Immunity Amsterdam, Amsterdam, The Netherlands
    Clin Infect Dis 48:973-8. 2009
    ....
  25. ncbi request reprint Recombination of HIV type 1C (C'/C") in Ethiopia: possible link of EthHIV-1C' to subtype C sequences from the high-prevalence epidemics in India and Southern Africa
    Georgios Pollakis
    Department of Human Retrovirology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    AIDS Res Hum Retroviruses 19:999-1008. 2003
    ..The possibility that viruses with a C' envelope have a biological advantage over the viruses with a C" envelope should be further investigated in biological and epidemiological studies...
  26. ncbi request reprint Highly active antiretroviral therapy with or without mycophenolate mofetil in treatment-naive HIV-1 patients
    Sanjay U C Sankatsing
    Department of Internal Medicine, Division of Infectious Diseases, Tropical Medicine and AIDS, University of Amsterdam, The Netherlands
    AIDS 18:1925-31. 2004
    ..To study the effect of mycophenolate mofetil (MMF) on the decay rate of plasma HIV-1 RNA and the latently infected cellular reservoir in treatment-naive patients starting antiretroviral therapy...
  27. ncbi request reprint Triple HIV-1 infection
    Antoinette C van der Kuyl
    N Engl J Med 352:2557-9. 2005
  28. ncbi request reprint A sudden rise in viral load is infrequently associated with HIV-1 superinfection
    Suzanne Jurriaans
    Laboratory of Experimental Virology, Department of Medical Microbiology, Center for Infection and Immunity Amsterdam CINIMA, Amsterdam, The Netherlands
    J Acquir Immune Defic Syndr 47:69-73. 2008
    ....
  29. pmc Lichen planus remission is associated with a decrease of human herpes virus type 7 protein expression in plasmacytoid dendritic cells
    Henry J C de Vries
    Department of Dermatology, Academic Medical Center, University of Amsterdam, P O Box 22700, 1100 DE Amsterdam, The Netherlands
    Arch Dermatol Res 299:213-9. 2007
    ..HHV-7 replicates in plasmacytoid dendritic cells in lesional lichen planus skin and diminishes after remission. This study further supports our hypothesis that HHV-7 is associated with lichen planus pathogenesis...
  30. ncbi request reprint HIV-1 seroreversion in an HIV-1-seropositive patient treated during acute infection with highly active antiretroviral therapy and mycophenolate mofetil
    Suzanne Jurriaans
    AIDS 18:1607-8. 2004