Madhuri Thakar

Summary

Publications

  1. pmc CD4 estimating reagents in dry format are compatible with conventional flow cytometer; FACSCalibur for estimation of absolute CD4 count & percentages
    Madhuri Thakar
    National AIDS Research Institute ICMR, Pune, India
    Indian J Med Res 137:346-55. 2013
  2. pmc Mortality in HIV infected individuals in Pune, India
    Manisha Ghate
    National AIDS Research Institute ICMR, Pune, India
    Indian J Med Res 133:414-20. 2011
  3. pmc Use of first line antiretroviral therapy from a free ART programme clinic in Pune, India - a preliminary report
    Manisha Ghate
    National AIDS Research Institute ICMR, Pune, India
    Indian J Med Res 137:942-9. 2013
  4. doi Short communication: HIV antigen-specific reactivation of HIV infection from cellular reservoirs: implications in the settings of therapeutic vaccinations
    Ashwini Shete
    National AIDS Research Institute, Pune, India
    AIDS Res Hum Retroviruses 28:835-43. 2012
  5. doi Incidence of common opportunistic infections in HIV-infected individuals in Pune, India: analysis by stages of immunosuppression represented by CD4 counts
    Manisha Ghate
    National AIDS Research Institute, Pune, India
    Int J Infect Dis 13:e1-8. 2009
  6. pmc A single amino acid substitution in the C4 region in gp120 confers enhanced neutralization of HIV-1 by modulating CD4 binding sites and V3 loop
    Rajesh Ringe
    Department of Molecular Virology, National AIDS Research Institute, Pune, India
    Virology 418:123-32. 2011
  7. doi Differential modulation of phenotypic composition of HIV-infected and -uninfected PBMCs during cryopreservation
    Ashwini Shete
    National AIDS Research Institute, Bhosari, Pune, India
    J Immunoassay Immunochem 34:333-45. 2013
  8. doi Short communication: genital tumor growth factor-β1 levels in HIV-infected Indian women are associated with reduced levels of innate antimicrobial products and increased HIV shedding
    Madhuri Thakar
    National AIDS Research Institute, MIDC Bhosari, Pune, Maharashtra, India
    AIDS Res Hum Retroviruses 30:648-53. 2014
  9. ncbi Safety & immunogenicity of tgAAC09, a recombinant adeno-associated virus type 2 HIV-1 subtype C vaccine in India
    Sanjay Mehendale
    National AIDS Research Institute ICMR, Pune, India
    Indian J Med Res 132:168-75. 2010
  10. pmc A review on peripheral blood CD4+ T lymphocyte counts in healthy adult Indians
    Ashwini Shete
    National AIDS Research Institute ICMR, Pune, India
    Indian J Med Res 132:667-75. 2010

Collaborators

Detail Information

Publications20

  1. pmc CD4 estimating reagents in dry format are compatible with conventional flow cytometer; FACSCalibur for estimation of absolute CD4 count & percentages
    Madhuri Thakar
    National AIDS Research Institute ICMR, Pune, India
    Indian J Med Res 137:346-55. 2013
    ..An attempt was made in this study to validate the ReaPan and Rea T Count dry reagents developed by ReaMetrix against the original BD Biosciences liquid reagents...
  2. pmc Mortality in HIV infected individuals in Pune, India
    Manisha Ghate
    National AIDS Research Institute ICMR, Pune, India
    Indian J Med Res 133:414-20. 2011
    ..Data on mortality in HIV infected individuals from prospective studies are scanty in India. We report here data on mortality in a systematically followed cohort of HIV infected individuals at Pune, Maharashtra, India...
  3. pmc Use of first line antiretroviral therapy from a free ART programme clinic in Pune, India - a preliminary report
    Manisha Ghate
    National AIDS Research Institute ICMR, Pune, India
    Indian J Med Res 137:942-9. 2013
    ..We carried out this study to analyze the impact of first line antiretroviral therapy in HIV infected patients attending a free ART roll out national programme clinic in Pune, India...
  4. doi Short communication: HIV antigen-specific reactivation of HIV infection from cellular reservoirs: implications in the settings of therapeutic vaccinations
    Ashwini Shete
    National AIDS Research Institute, Pune, India
    AIDS Res Hum Retroviruses 28:835-43. 2012
    ....
  5. doi Incidence of common opportunistic infections in HIV-infected individuals in Pune, India: analysis by stages of immunosuppression represented by CD4 counts
    Manisha Ghate
    National AIDS Research Institute, Pune, India
    Int J Infect Dis 13:e1-8. 2009
    ..Opportunistic infections (OIs) influence the morbidity and mortality due to HIV infections. Data from India on the incidence of OIs among HIV-infected individuals by stages of immunodeficiency are scarce...
  6. pmc A single amino acid substitution in the C4 region in gp120 confers enhanced neutralization of HIV-1 by modulating CD4 binding sites and V3 loop
    Rajesh Ringe
    Department of Molecular Virology, National AIDS Research Institute, Pune, India
    Virology 418:123-32. 2011
    ..Substitution of I424M in unrelated Envs also showed similar neutralization phenotype, indicating that M424 in C4 region induces exposure of neutralizing epitopes particularly in CD4 binding sites and V3 loop...
  7. doi Differential modulation of phenotypic composition of HIV-infected and -uninfected PBMCs during cryopreservation
    Ashwini Shete
    National AIDS Research Institute, Bhosari, Pune, India
    J Immunoassay Immunochem 34:333-45. 2013
    ..Thus, cryopreservation resulted in differential effect on phenotypic composition of PBMCs in HIV-infected and -uninfected individuals. ..
  8. doi Short communication: genital tumor growth factor-β1 levels in HIV-infected Indian women are associated with reduced levels of innate antimicrobial products and increased HIV shedding
    Madhuri Thakar
    National AIDS Research Institute, MIDC Bhosari, Pune, Maharashtra, India
    AIDS Res Hum Retroviruses 30:648-53. 2014
    ..Considering the known association of HIV and cervical cancers, it will also be important to assess the predictive capacity of TGF-β1 levels in HIV-associated cervical malignancies...
  9. ncbi Safety & immunogenicity of tgAAC09, a recombinant adeno-associated virus type 2 HIV-1 subtype C vaccine in India
    Sanjay Mehendale
    National AIDS Research Institute ICMR, Pune, India
    Indian J Med Res 132:168-75. 2010
    ..This paper reports the safety and immunogenicity of tgAAC09 in healthy adult Indian volunteers...
  10. pmc A review on peripheral blood CD4+ T lymphocyte counts in healthy adult Indians
    Ashwini Shete
    National AIDS Research Institute ICMR, Pune, India
    Indian J Med Res 132:667-75. 2010
    ..The published data on the CD4+ T cells count in healthy Indian adult population have been reviewed, analyzed and discussed in this review article. The requirement of establishment of reference ranges in Indian population is discussed...
  11. pmc The effects of antiretroviral treatment initiation on cognition in HIV-infected individuals with advanced disease in Pune, India
    Manisha Ghate
    National AIDS Research Institute, Post Box 1895, G 73, MIDC, Bhosari, Pune, Maharashtra, 411026, India
    J Neurovirol 21:391-8. 2015
    ..Overall, the degree of improvement associated with the magnitude of rise in CD4 suggests the possibility that early, mild subclinical deficits may also benefit from treatment...
  12. pmc Clinical profile of HIV infected patients attending a HIV referral clinic in Pune, India
    Megha Antwal
    National AIDS Research Institute ICMR, Pune, India
    Indian J Med Res 140:271-7. 2014
    ..This has progressively changed the clinical profile of HIV infected individuals and this study documents the clinical presentation of individuals positive for HIV in 2010, in Pune, Maharashtra, India...
  13. doi Heparin and EDTA anticoagulants differentially affect the plasma cytokine levels in humans
    Rahul Patil
    Division of Immunology, National AIDS Research Institute, Pune, Maharashtra, India
    Scand J Clin Lab Invest 73:452-5. 2013
    ..Hence, it is important to choose an appropriate anticoagulant before the estimation of cytokines for reliable use of plasma cytokines as biomarkers in patient management...
  14. pmc In vitro sensitization of T cells with DC-associated/delivered HIV constructs can induce a polyfunctional CTL response, memory T-cell response, and virus suppression
    Swarali Kurle
    Department of Immunology, National AIDS Research Institute, Bhosari, Pune, India
    Viral Immunol 25:45-54. 2012
    ....
  15. pmc Colposcopically observed vascular changes in the cervix in relation to the hormonal levels and menstrual cycle
    Smita N Joshi
    National AIDS Research Institute, Pune, India
    J Low Genit Tract Dis 12:293-9. 2008
    ..We assessed colposcopically observed vascular changes occurring in the cervix in relation to cyclical hormonal variation in healthy women...
  16. pmc Utility of the point of care CD4 analyzer, PIMA, to enumerate CD4 counts in the field settings in India
    Madhuri Thakar
    Department of Immunology, National AIDS Research Institute, G 73, MIDC, Bhosari, Pune, 411 026, India
    AIDS Res Ther 9:26. 2012
    ..abstract:..
  17. pmc Variations in autologous neutralization and CD4 dependence of b12 resistant HIV-1 clade C env clones obtained at different time points from antiretroviral naïve Indian patients with recent infection
    Rajesh Ringe
    Department of Molecular Virology, National AIDS Research Institute, Indian Council of Medical Research, G 73 MIDC, Bhosari, Pune, India
    Retrovirology 7:76. 2010
    ....
  18. ncbi Cervical squamous intra-epithelial changes and human papillomavirus infection in women infected with human immunodeficiency virus in Pune, India
    Smita N Joshi
    National AIDS Research Institute, Pune, India
    J Med Virol 76:470-5. 2005
    ..5 per 100 person year of follow-up. In order to prevent thousands of deaths due to cervical cancer in India, there is a need for strengthening the Pap smear screening program and HPV vaccine development...
  19. doi Expansion of defective NK cells in early HIV type 1C infection: a consequence of reduced CD161 expression
    Archana Kulkarni
    National AIDS Research Institute, Pune Indian Council of Medical Research, Bhosari, Pune, India
    AIDS Res Hum Retroviruses 28:100-5. 2012
    ..The reduction in CD161 expression on the defective NK cells in early HIV infection is thus indicative of the role of innate immune cells in early control of HIV infection...
  20. doi A phase 1 study to evaluate the safety and immunogenicity of a recombinant HIV type 1 subtype C adeno-associated virus vaccine
    Sanjay Mehendale
    National AIDS Research Institute, Pune, India
    AIDS Res Hum Retroviruses 24:873-80. 2008
    ..All responses were to Gag epitopes. tgAAC09 appears to be safe, well-tolerated, and modestly immunogenic. Further evaluation of higher doses of tgAAC09 and boost injections is ongoing in Africa...