Sornchai Looareesuwan

Summary

Affiliation: Mahidol University
Country: Thailand

Publications

  1. ncbi request reprint Haematinic treatment of anaemia increases the risk of Plasmodium vivax malaria in pregnancy
    Mathieu Nacher
    Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Road, Bangkok 10400, Thailand
    Trans R Soc Trop Med Hyg 97:273-6. 2003
  2. pmc Differences in genetic population structures of Plasmodium falciparum isolates from patients along Thai-Myanmar border with severe or uncomplicated malaria
    Pannapa Susomboon
    Department of Appropriate Technology Development and Transfer Research Institute, International Medical Center of Japan, Shinjuku, Tokyo, Japan
    Malar J 7:212. 2008
  3. ncbi request reprint The rational use of qinghaosu and its derivatives: what is the future of new compounds?
    S Looareesuwan
    Hospital for Tropical Disease, Faculty of Tropical Medicine Mahidol University, Bangkok, Thailand
    Med Trop (Mars) 58:89-92. 1998
  4. ncbi request reprint Chlorproguanil-dapsone for malaria in Africa
    Sornchai Looareesuwan
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand
    Lancet 363:1838-9. 2004
  5. ncbi request reprint Artesunate and mefloquine given simultaneously for three days via a prepacked blister is equally effective and tolerated as a standard sequential treatment of uncomplicated acute Plasmodium falciparum malaria: randomized, double-blind study in Thailand
    S Krudsood
    Bangkok Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 67:465-72. 2002
  6. pmc Clinical trial of oral artesunate with or without high-dose primaquine for the treatment of vivax malaria in Thailand
    Udomsak Silachamroon
    Department of Clinical Tropical Medicine and Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 69:14-8. 2003
  7. pmc Limited polymorphism in the dihydropteroate synthetase gene (dhps) of Plasmodium vivax isolates from Thailand
    Mallika Imwong
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Antimicrob Agents Chemother 49:4393-5. 2005
  8. pmc In vitro antimalarial activity of azithromycin, artesunate, and quinine in combination and correlation with clinical outcome
    Harald Noedl
    Department of Specific Prophylaxis and Tropical Medicine, Center for Physiology and Pathophysiology, Medical University of Vienna, Austria, and Hospital for Tropical Diseases, Bangkok, Thailand
    Antimicrob Agents Chemother 51:651-6. 2007
  9. pmc Clinical efficacy of chloroquine versus artemether-lumefantrine for Plasmodium vivax treatment in Thailand
    Srivicha Krudsood
    Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand
    Korean J Parasitol 45:111-4. 2007
  10. pmc Genetic analysis of the dihydrofolate reductase-thymidylate synthase gene from geographically diverse isolates of Plasmodium malariae
    Naowarat Tanomsing
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Antimicrob Agents Chemother 51:3523-30. 2007

Collaborators

Detail Information

Publications153 found, 100 shown here

  1. ncbi request reprint Haematinic treatment of anaemia increases the risk of Plasmodium vivax malaria in pregnancy
    Mathieu Nacher
    Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Road, Bangkok 10400, Thailand
    Trans R Soc Trop Med Hyg 97:273-6. 2003
    ..vivax malaria. In P. vivax-endemic areas, systematic iron and folate supplementation confers both benefit and risk in pregnancy...
  2. pmc Differences in genetic population structures of Plasmodium falciparum isolates from patients along Thai-Myanmar border with severe or uncomplicated malaria
    Pannapa Susomboon
    Department of Appropriate Technology Development and Transfer Research Institute, International Medical Center of Japan, Shinjuku, Tokyo, Japan
    Malar J 7:212. 2008
    ..The population genetic structures of P. falciparum isolates from patients with either severe or uncomplicated malaria were examined...
  3. ncbi request reprint The rational use of qinghaosu and its derivatives: what is the future of new compounds?
    S Looareesuwan
    Hospital for Tropical Disease, Faculty of Tropical Medicine Mahidol University, Bangkok, Thailand
    Med Trop (Mars) 58:89-92. 1998
    ..We found that the three preparations are well tolerated, safe, and efficacious...
  4. ncbi request reprint Chlorproguanil-dapsone for malaria in Africa
    Sornchai Looareesuwan
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand
    Lancet 363:1838-9. 2004
  5. ncbi request reprint Artesunate and mefloquine given simultaneously for three days via a prepacked blister is equally effective and tolerated as a standard sequential treatment of uncomplicated acute Plasmodium falciparum malaria: randomized, double-blind study in Thailand
    S Krudsood
    Bangkok Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 67:465-72. 2002
    ..falciparum malaria. It is likely that the prepacked blister approach translates clinically into a better patient compliance, thereby contributing to limit the development of drug resistance...
  6. pmc Clinical trial of oral artesunate with or without high-dose primaquine for the treatment of vivax malaria in Thailand
    Udomsak Silachamroon
    Department of Clinical Tropical Medicine and Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 69:14-8. 2003
    ..The combination of five days of artesunate and 14 days of primaquine is a highly effective and generally well-tolerated treatment regimen for vivax malaria in Thailand...
  7. pmc Limited polymorphism in the dihydropteroate synthetase gene (dhps) of Plasmodium vivax isolates from Thailand
    Mallika Imwong
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Antimicrob Agents Chemother 49:4393-5. 2005
    ..Mutations of Pvdhps and Pvdhfr were correlated. Multiple mutations were associated with high-grade sulfadoxine-pyrimethamine resistance...
  8. pmc In vitro antimalarial activity of azithromycin, artesunate, and quinine in combination and correlation with clinical outcome
    Harald Noedl
    Department of Specific Prophylaxis and Tropical Medicine, Center for Physiology and Pathophysiology, Medical University of Vienna, Austria, and Hospital for Tropical Diseases, Bangkok, Thailand
    Antimicrob Agents Chemother 51:651-6. 2007
    ....
  9. pmc Clinical efficacy of chloroquine versus artemether-lumefantrine for Plasmodium vivax treatment in Thailand
    Srivicha Krudsood
    Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand
    Korean J Parasitol 45:111-4. 2007
    ....
  10. pmc Genetic analysis of the dihydrofolate reductase-thymidylate synthase gene from geographically diverse isolates of Plasmodium malariae
    Naowarat Tanomsing
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Antimicrob Agents Chemother 51:3523-30. 2007
    ..Five isolates with the wild-type DHFR could be assayed for drug susceptibility in vitro and were found to be sensitive to pyrimethamine (mean 50% inhibitory concentration, 2.24 ng/ml [95% confidence interval, 0.4 to 3.1])...
  11. ncbi request reprint Artesunate-dapsone-proguanil treatment of falciparum malaria: genotypic determinants of therapeutic response
    Sivicha Krudsood
    Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Road, Bangkok 10400, Thailand
    Trans R Soc Trop Med Hyg 99:142-9. 2005
    ..The addition of artesunate considerably augments the antimalarial activity of the biguanide-dapsone combination, but this is insufficient for infections with parasites carrying the highly antifol-resistant Pfdhfr I164L mutation...
  12. pmc Intravenous ibuprofen (IV-ibuprofen) controls fever effectively in adults with acute uncomplicated Plasmodium falciparum malaria but prolongs parasitemia
    Srivicha Krudsood
    Department of Tropical Hygiene, Department of Clinical Tropical Medicine, Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 83:51-5. 2010
    ..0024]). This difference did not appear to be clinically important Adverse events, none considered severe, occurred equally in both groups. IV-ibuprofen was effective and well tolerated in reducing fever in febrile inpatients with malaria...
  13. ncbi request reprint Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites
    Mallika Imwong
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Infect Dis 195:927-33. 2007
    ..Thus, reappearance of parasitemia after treatment can result from relapse, recrudescence, or reinfection. It has been assumed that parasites causing relapse would be a subset of the parasites that caused the primary infection...
  14. pmc Clinical experience with intravenous quinine, intramuscular artemether and intravenous artesunate for the treatment of severe malaria in Thailand
    Srivicha Krudsood
    Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 34:54-61. 2003
    ..Effective therapy for severe falciparum malaria can be provided by either intravenous artesunate followed by mefloquine or by intravenous quinine followed by tetracycline...
  15. pmc Efficacy of Artequick versus artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria in Thailand
    Noppadon Tangpukdee
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 39:1-8. 2008
    ..We conclude that Artequick was as effective and well tolerated as artesunate-mefloquine and could be used as an alternative treatment for multidrug-resistant Plasmodium falciparum malaria in Southeast Asia...
  16. pmc Minor liver profile dysfunctions in Plasmodium vivax, P. malaria and P. ovale patients and normalization after treatment
    Noppadon Tangpukdee
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Korean J Parasitol 44:295-302. 2006
    ..These minor abnormalities returned to normal within a few weeks after treatment with therapies based on artemisinin derivatives...
  17. pmc Hyponatraemia and hypokalaemia in adults with uncomplicated malaria in Thailand
    Vipa Thanachartwet
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Ratchathevee, Bangkok, Thailand
    Trop Doct 38:155-7. 2008
    ..001). Other independent predictors for hypokalaemia were Plasmodium vivax infection, female gender; and for hyponatraemia, P. falciparum infection, male gender, concentrations of G-6-PD and serum bicarbonate...
  18. ncbi request reprint Are extensive T cell epitope polymorphisms in the Plasmodium falciparum circumsporozoite antigen, a leading sporozoite vaccine candidate, selected by immune pressure?
    Chutima Kumkhaek
    Department of Microbiology and Immunology, Mahidol University, Bangkok, Thailand
    J Immunol 175:3935-9. 2005
    ..We provide evidence that polymorphisms in the T cell epitopes of a malaria vaccine candidate are unlikely to have been selected by immune pressure in the human host...
  19. pmc Practical PCR genotyping protocols for Plasmodium vivax using Pvcs and Pvmsp1
    Mallika Imwong
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Malar J 4:20. 2005
    ..P. vivax resistance to drugs has more recently emerged and monitoring the situation would be helped, as for P. falciparum, by molecular methods that can be used to characterize parasites in field studies and drug efficacy trials...
  20. pmc Transmission-blocking activities of quinine, primaquine, and artesunate
    Kesinee Chotivanich
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Antimicrob Agents Chemother 50:1927-30. 2006
    ..Artesunate both prevents the maturation of immature P. falciparum gametocytes and reduces the transmission potential of mature gametocytes. Both of these effects may contribute to reducing malaria transmission...
  21. pmc Pharmacokinetics of oral doxycycline during combination treatment of severe falciparum malaria
    Paul N Newton
    Mae Sot, Tak and Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Rd, Bangkok 10400, Thailand
    Antimicrob Agents Chemother 49:1622-5. 2005
    ..The data suggest that the doses of doxycycline currently recommended (circa 3.5 mg/kg of body weight daily) may not be optimal...
  22. ncbi request reprint Randomized, controlled dose-optimization studies of dihydroartemisinin-piperaquine for the treatment of uncomplicated multidrug-resistant falciparum malaria in Thailand
    Elizabeth A Ashley
    Shoklo Malaria Research Unit, Mae Sot, and Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Infect Dis 190:1773-82. 2004
    ..This raised the possibility that the efficacy of the current coformulation may not be optimal in the treatment of multidrug-resistant falciparum malaria...
  23. pmc Dose ranging studies of new artemisinin-piperaquine fixed combinations compared to standard regimens of artemisisnin combination therapies for acute uncomplicated falciparum malaria
    Srivicha Krudsood
    Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, 420 6 Ratchawithi Road, Bangkok 10400, Thailand
    Southeast Asian J Trop Med Public Health 38:971-8. 2007
    ..These results suggest that a 3-day course of artemisinin-piperaquine at 3.2 mg/kg and 16.0 mg/kg, respectively, deserve further evaluation as an alternative treatment for multidrug-resistant P. falciparum malaria...
  24. ncbi request reprint In vitro efficacy of antimalarial drugs against Plasmodium vivax on the western border of Thailand
    Kesinee Chotivanich
    Faculty of Tropical Medicine, and Department of Pathobiology, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 70:395-7. 2004
    ..5 ng/mL. Compared with P. falciparum in this area, P. vivax was more sensitive to chloroquine and artesunate, equally sensitive to quinine, and more resistant to mefloquine...
  25. ncbi request reprint Randomized comparison of artesunate and quinine in the treatment of severe falciparum malaria
    Paul N Newton
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Clin Infect Dis 37:7-16. 2003
    ..03). Artesunate is at least as effective as quinine in the treatment of adults with severe malaria. Larger trials are required to determine whether mortality is reduced among patients treated with artesunate...
  26. ncbi request reprint Azithromycin combination therapy with artesunate or quinine for the treatment of uncomplicated Plasmodium falciparum malaria in adults: a randomized, phase 2 clinical trial in Thailand
    Harald Noedl
    1Department of Immunology and Medicine, USAMC AFRIMS, Bangkok, Thailand
    Clin Infect Dis 43:1264-71. 2006
    ..Azithromycin is a macrolide antibiotic that is particularly attractive as an antimalarial because of its safety in children and the extensive experience with its use during pregnancy...
  27. ncbi request reprint Recrudescence in artesunate-treated patients with falciparum malaria is dependent on parasite burden not on parasite factors
    Wanida Ittarat
    Department of Clinical Microscopy, Faculty of Medical Technology, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 68:147-52. 2003
    ..This study suggests (1) recrudescence after treatment with artesunate is not the result of inherent parasite resistance, and (2) admission parasitemia may be useful in choosing therapeutic options...
  28. pmc Safety and tolerability of elubaquine (bulaquine, CDRI 80/53) for treatment of Plasmidium vivax malaria in Thailand
    Srivicha Krudsood
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Korean J Parasitol 44:221-8. 2006
    ..In conclusion, elubaquine, as anti-relapse therapy for P. vivax malaria, was as safe and well tolerated as primaquine and did not cause clinically significant hemolysis...
  29. ncbi request reprint Early treatment failure in severe malaria resulting from abnormally low plasma quinine concentrations
    Paul N Newton
    Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand
    Trans R Soc Trop Med Hyg 100:184-6. 2006
    ..Plasma quinine concentrations were subtherapeutic. Abnormal quinine pharmacokinetics may explain sporadic reports of quinine treatment failures in severe malaria...
  30. pmc Activities of artesunate and primaquine against asexual- and sexual-stage parasites in falciparum malaria
    Sasithon Pukrittayakamee
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Antimicrob Agents Chemother 48:1329-34. 2004
    ..038). These results suggest that artesunate predominantly inhibits gametocyte development whereas primaquine accelerates gametocyte clearance in P. falciparum malaria...
  31. pmc High-dose primaquine regimens against relapse of Plasmodium vivax malaria
    Srivicha Krudsood
    Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 78:736-40. 2008
    ..Treatment of P. vivax malaria with artesunate for 5 days followed by high-dose primaquine, 30 mg twice a day for 7 days, was highly effective, well-tolerated, and equivalent or superior to the standard regimen of primaquine therapy...
  32. ncbi request reprint Randomized trial of 3-dose regimens of tafenoquine (WR238605) versus low-dose primaquine for preventing Plasmodium vivax malaria relapse
    Douglas S Walsh
    Department of Immunology and Medicine, US Army Medical Component, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Clin Infect Dis 39:1095-103. 2004
    ....
  33. ncbi request reprint Efficacy of atovaquone-proguanil for treatment of acute multidrug-resistant Plasmodium falciparum malaria in Thailand
    Srivicha Krudsood
    Bangkok Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 76:655-8. 2007
    ..These data indicate that atovaquone-proguanil remains highly efficacious for the treatment of multidrug-resistant P. falciparum malaria in Thailand...
  34. ncbi request reprint The future outlook of antimalarial drugs and recent work on the treatment of malaria
    Polrat Wilairatana
    Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Arch Med Res 33:416-21. 2002
    ..In treatment of severe malaria, antimalarial drugs of choice are intravenous quinine or artemisinin derivatives...
  35. ncbi request reprint Monocyte chemoattractant protein 1 (MCP-1) gene polymorphism is not associated with severe and cerebral malaria in Thailand
    Naowarut Dechkum
    Department of Microbiology and Immunology, Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol Univeristy, Bangkok 10400, Thailand
    Jpn J Infect Dis 59:239-44. 2006
    ..The most common haplotype was GGAC. The results indicated that MCP-1 gene polymorphisms were not associated with malaria severity, implying that MCP-1 was not a cause of malaria severity in this Thai population...
  36. doi request reprint Dynamic changes in white blood cell counts in uncomplicated Plasmodium falciparum and P. vivax malaria
    Noppadon Tangpukdee
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Parasitol Int 57:490-4. 2008
    ..falciparum and P. vivax malaria are significantly lower than previously assumed for estimating malaria-parasite density. However, these abnormalities returned to normal within several weeks after artemisinin-derivative-based treatment...
  37. ncbi request reprint A survey of the Th2R and Th3R allelic variants in the circumsporozoite protein gene of P. falciparum parasites from western Thailand
    Chutima Kumkhaek
    Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 35:281-7. 2004
    ..However, the Th2R*05 and the Th3R*01 allelic variants predominated, as they were found in more than 70% of the 101 sequences obtained...
  38. ncbi request reprint Association of intestinal helminths with decreased liver size and sCD23 concentration during falciparum malaria
    Mathieu Nacher
    Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 35:31-4. 2004
    ..40, p < 0.0001). All the above results remained significant after controlling for potential confounders. These results are compatible with a CD23/NO-mediated decrease in liver size in helminth-infected patients...
  39. ncbi request reprint Risk factors for Plasmodium vivax gametocyte carriage in Thailand
    Mathieu Nacher
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 71:693-5. 2004
    ..97-0.99, P = 0.006), albumin (AOR = 0.67 per 10 g/mL increase, 95% CI = 0.5-0.9, P = 0.007), and anion gap (AOR = 1.1 per unit increase, 95% CI = 1.02-1.14, P = 0.009). The possible significance of these observations is discussed...
  40. ncbi request reprint The use of flow cytometry as a diagnostic test for malaria parasites
    Varee Wongchotigul
    Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 35:552-9. 2004
    ..Further improvement, by eliminating this interference, will make the FCM one of the most promising tests for malaria diagnosis...
  41. ncbi request reprint Suppressive effects of the anti-oxidant N-acetylcysteine on the anti-malarial activity of artesunate
    Peera Arreesrisom
    Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand
    Parasitol Int 56:221-6. 2007
    ..The results herein caution the use of adjunctive treatment for malaria infection. Combination of antagonistic drugs may lead to adverse effects...
  42. ncbi request reprint Emergence and clearance of gametocytes in uncomplicated Plasmodium falciparum malaria
    Watcharapong Piyaphanee
    Department of Clinical Tropical Medicine and Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 74:432-5. 2006
    ..However, 21 patients (9.8%) still had gametocytemia on discharge. Gametocytemia generally is present within the first 24 hours after admission, and emerges in only 1.9% of patients later on during treatment with artemisinin...
  43. ncbi request reprint Expression of toll-like receptors on antigen-presenting cells in patients with falciparum malaria
    Somying Loharungsikul
    Department of Clinical Microbiology, Faculty of Medical Technology, Mahidol University, 2 Prannok Road, Bangkok Noi, Bangkok 10700, Thailand
    Acta Trop 105:10-5. 2008
    ..These findings suggested that TLRs might play role in innate immune recognition in which the differential expression of TLRs on APCs could be regulated by the P. falciparum parasite...
  44. pmc Suppression of Plasmodium falciparum by serum collected from a case of Plasmodium vivax infection
    Yoshiro Nagao
    Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Road, Bangkok, 10400, Thailand
    Malar J 7:113. 2008
    ..The authors investigate the hypothesis that immunological responses stimulated by P. vivax may play a role in suppressing co-infecting P. falciparum...
  45. pmc Defective erythropoietin production and reticulocyte response in acute Plasmodium falciparum malaria-associated anemia
    Wattana Leowattana
    Department of Clinical Tropical Medicine, Mahidol University, 420 6 Ratchawithi Road, Bangkok 10400, Thailand
    Southeast Asian J Trop Med Public Health 39:581-8. 2008
    ..Our findings may provide the basis for further study into the choice of therapeutic strategies to treat acute P. falciparum malaria-associated anemia with recombinant human Epo to correct refractory anemia due to malaria...
  46. ncbi request reprint Six-years monitoring the efficacy of the combination of artesunate and mefloquine for the treatment of uncomplicated falciparum malaria
    Yupaporn Wattanakoon
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 34:542-5. 2003
    ..The adverse effects of anorexia, nausea, vomiting and diarrhea were mild and transient for mefloquine. The combination can be used as stand by treatment in areas of multi-drug resistant falciparum malaria...
  47. ncbi request reprint Open randomized trial of oral artemether alone and a sequential combination with mefloquine for acute uncomplicated falciparum malaria
    S Looareesuwan
    Department of Clinical Tropical Medicine, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 56:613-7. 1997
    ..A seven-day regimen of artemether alone (750 mg) is also very effective, yet requires prolonged administration of drug after malaria symptoms disappear...
  48. ncbi request reprint Quantitation of cell-derived microparticles in plasma using flow rate based calibration
    Duangdao Nantakomol
    Department of Tropical Pathology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 39:146-53. 2008
    ..There was no significant correlation between the total number of MPs and parasitemia. Flow rate based calibration is a simple, reliable, reproducible method and more affordable to quantitate MPs...
  49. pmc N-acetylcysteine in severe falciparum malaria in Thailand
    Sombat Treeprasertsuk
    Bangkok Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 34:37-42. 2003
    ..The excellent results with NAC, the lack of adverse effects, and the rationale for NAC benefit supports the need for a large, double blind trial of NAC as an adjunctive therapy for severe malaria...
  50. pmc Predictive score of uncomplicated falciparum malaria patients turning to severe malaria
    Noppadon Tangpukdee
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Korean J Parasitol 45:273-82. 2007
    ..However, the MSPS may need revalidation in different geographical areas before utilized at specific places...
  51. ncbi request reprint Platelet-induced autoagglutination of Plasmodium falciparum-infected red blood cells and disease severity in Thailand
    Kesinee Chotivanich
    Faculty of Tropical Medicine, Faculty of Science, Mahidol University, Bangkok, Thailand
    J Infect Dis 189:1052-5. 2004
    ..01). In multivariate analyses, high parasitemia and cerebral malaria were associated independently with parasite agglutination...
  52. pmc Travelers' malaria among foreigners at the Hospital for Tropical Diseases, Bangkok, Thailand - a 6-year review (2000-2005)
    Watcharapong Piyaphanee
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Korean J Parasitol 44:229-32. 2006
    ..Only 1 P. falciparum case had complications. All cases were successfully treated with standard antimalarial drugs. Only 3 of the 21 cases were thought to be acquired in Thailand, the rest were regarded to be imported...
  53. ncbi request reprint Efficacy of ivermectin treatment of cutaneous gnathostomiasis evaluated by placebo-controlled trial
    Valai Bussaratid
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, 420 6 Ratchawithi Road, Bangkok 10400, Thailand
    Southeast Asian J Trop Med Public Health 37:433-40. 2006
    ..Further studies with different doses of ivermectin and larger sample sizes, and close monitoring for ivermectin tolerability and treatment response are necessary to confirm an efficacy of ivermectin...
  54. ncbi request reprint Relative levels of IL4 and IFN-gamma in complicated malaria: association with IL4 polymorphism and peripheral parasitemia
    Piyatida Tangteerawatana
    Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Road, Bangkok 10400, Thailand
    Acta Trop 101:258-65. 2007
    ..283, p=0.046). These results suggest that the IL4-590 C/T polymorphism may play a role in the balance between IL4 and IFN-gamma, as well as in the control of parasitemia, which in turn may alter the severity of malaria...
  55. ncbi request reprint IgG antibody profile to c-terminal region of Plasmodium vivax merozoite surface protein-1 in Thai individuals exposed to malaria
    Nada Pitabut
    Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 38:1-7. 2007
    ..Our data indicate that individuals exposed to vivax malaria in Thailand developed antibodies to the potential candidate vaccine antigen, PvMSP1 (C-terminal)...
  56. ncbi request reprint A randomized, double-blind, comparative trial of a new oral combination of artemether and benflumetol (CGP 56697) with mefloquine in the treatment of acute Plasmodium falciparum malaria in Thailand
    S Looareesuwan
    Department of Clinical Tropical Medicine and Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Thailand
    Am J Trop Med Hyg 60:238-43. 1999
    ..001). This study revealed that CGP 56697 is effective against multidrug-resistant Plasmodium falciparum malaria in Thailand, but higher doses will probably be needed to improve the cure rate...
  57. ncbi request reprint An open randomized clinical trial of Artekin vs artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria
    N Tangpukdee
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 36:1085-91. 2005
    ..We conclude that Artekin was as effective and well-tolerated as artesunate-mefloquine, and can be used alternatively as the current treatment for multidrug-resistant P. falciparum malaria...
  58. ncbi request reprint The epidemiology of patients with severe malaria who died at the Hospital for Tropical Diseases, 1991-2004
    Suparp Vannaphan
    Intensive Care Unit, Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 36:385-9. 2005
    ..The most common complication of malaria was cerebral malaria (77.1%). The socioeconomic and demographic characteristics of those who died are examined here, as well as the cost of their treatment...
  59. ncbi request reprint Central role of the spleen in malaria parasite clearance
    Kesinee Chotivanich
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Infect Dis 185:1538-41. 2002
    ..Current criteria for high-grade antimalarial drug resistance that are based on changes in parasitemia are not appropriate for asplenic patients...
  60. ncbi request reprint Blood stage Plasmodium falciparum antigens induce immunoglobulin class switching in human enriched B cell culture
    Pachuen Potup
    Department of Tropical Radioisotopes, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 40:651-64. 2009
    ..falciparum-stimulated B cells...
  61. ncbi request reprint The effects of quinine and chloroquine antimalarial treatments in the first trimester of pregnancy
    Rose McGready
    Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand
    Trans R Soc Trop Med Hyg 96:180-4. 2002
    ..These results suggest that therapeutic doses of quinine and chloroquine are safe to use in the first trimester of pregnancy...
  62. ncbi request reprint Hemoglobin E: a balanced polymorphism protective against high parasitemias and thus severe P falciparum malaria
    Kesinee Chotivanich
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Blood 100:1172-6. 2002
    ....
  63. ncbi request reprint Treatment of acute, uncomplicated, falciparum malaria with oral dihydroartemisinin
    S Looareesuwan
    Department of Clinical Tropical Medicine, Mahidol University, Bangkok, Thailand
    Ann Trop Med Parasitol 90:21-28. 1996
    ..Comparisons with other conventional antimalarial drugs in a large, double-blind, randomized trial and studies of dihydroartemisinin in combination with other, long-acting antimalarials are needed...
  64. ncbi request reprint Clinical trial of artesunate and artemether on multidrug resistant falciparum malaria in Thailand. A preliminary report
    D Bunnag
    Department of Clinical Tropical Medicine, Bangkok Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Thailand
    Southeast Asian J Trop Med Public Health 22:380-5. 1991
    ..Slight reduction of neutrophil leucocytes and reticulocytes was observed. Further studies of artesunate and artemether should be carried out to find the optimum dosage regimen and to clarify the hematological effects...
  65. ncbi request reprint A comparison of artesunate alone with combined artesunate and quinine in the parenteral treatment of acute falciparum malaria
    P N Newton
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Trans R Soc Trop Med Hyg 95:519-23. 2001
    ..There is no benefit evident from combining parenteral administration of these 2 antimalarial drugs in the acute phase of treatment...
  66. ncbi request reprint A systematic overview of published antimalarial drug trials
    Hla Yin Myint
    Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Rd, Bangkok 10400, Thailand
    Trans R Soc Trop Med Hyg 98:73-81. 2004
    ..The quality of safety and efficacy data for recently evaluated drugs contrasts with a relative paucity of data for older 'established' compounds...
  67. pmc Longitudinal study of Plasmodium falciparum and Plasmodium vivax in a Karen population in Thailand
    Waraphon Phimpraphi
    Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Malar J 7:99. 2008
    ..falciparum prevalence and incidence rates, but has been less successful for P. vivax. The high transmissibility of P. vivax and its capacity to relapse have been suggested to make it a harder parasite species to control...
  68. pmc Febrile temperatures induce cytoadherence of ring-stage Plasmodium falciparum-infected erythrocytes
    Rachanee Udomsangpetch
    Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand
    Proc Natl Acad Sci U S A 99:11825-9. 2002
    ..Fever induced cytoadherence is likely to have important pathological consequences and may explain both clinical deterioration with fever in severe malaria and the effects of antipyretics on parasite clearance...
  69. pmc Management of malaria in Thailand
    Udomsak Silachamroon
    Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand
    Korean J Parasitol 40:1-7. 2002
    ..Oral mefloquine (25 mg/kg divided into two doses 8 hrs apart) should be given at the end of the artemisinin treatment course to reduce recrudescence...
  70. ncbi request reprint Neuropathologic toxicity of artemisinin derivatives in a mouse model
    Apichart Nontprasert
    Department of Clinical Tropical Medicine and Bangkok Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 67:423-9. 2002
    ..Thus clinical assessment was a sensitive measure of neurotoxicity. There may be a reversible component to artemether neurotoxicity...
  71. ncbi request reprint Plasmodium falciparum: effect of anti-malarial drugs on the production and secretion characteristics of histidine-rich protein II
    Harald Noedl
    Department of Immunology and Medicine, Armed Forces Research Institute of Medical Sciences USAMC AFRIMS, Bangkok Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Exp Parasitol 102:157-63. 2002
    ..HRP2 therefore allows for a very accurate estimation of parasite development and its inhibition and may therefore be ideally suited for use in drug sensitivity or bioassays...
  72. ncbi request reprint Factors associated with acute renal failure in severe falciparum [corrected] malaria patients
    Suparp Vannaphan
    Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, 420 6 Ratchawithi Road, Bangkok 10400, Thailand
    Southeast Asian J Trop Med Public Health 41:1042-7. 2010
    ..05). Patients who have ARF and any of these clinical or laboratory manifestations of severe malaria should be monitored and managed properly, since early detection and treatment may reduce morbidity and mortality...
  73. ncbi request reprint Malaria and amphetamine 'horse tablets' in Thailand
    Paul N Newton
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Trop Med Int Health 8:17-8. 2003
    ..This comorbidity may cause diagnostic confusion, alter malaria pathophysiology and lead to drug interactions...
  74. pmc In vivo assessment of drug efficacy against Plasmodium falciparum malaria: duration of follow-up
    Kasia Stepniewska
    Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Rd, Bangkok 10400, Thailand
    Antimicrob Agents Chemother 48:4271-80. 2004
    ..94) or if the entomological inoculation rate was known. In the assessment of drug efficacy against falciparum malaria, 28 days should be the minimum period of follow-up...
  75. ncbi request reprint Evaluation of the KAT-Quick Malaria Rapid Test for rapid diagnosis of falciparum malaria in Thailand
    Kasinee Buchachart
    Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 35:35-7. 2004
    ..5), the specificity was 92% (95% CI = 80-99), the accuracy was 94% and the reliability was 85%. These findings suggest that the KAT test is of potential interest in the diagnosis of falciparum malaria in Thailand...
  76. pmc Peripheral gangrene in patients with severe falciparum malaria: report of 3 cases
    Vipa Thanachartwet
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand
    Korean J Parasitol 44:139-43. 2006
    ..These patients were diagnosed as having severe malaria with peripheral gangrene. The resolution of gangrene was successfully achieved by treatment with artesunate and conservative treatment in 2 of 3 cases...
  77. ncbi request reprint An ultrastructural study of the brain in fatal Plasmodium falciparum malaria
    Emsri Pongponratn
    Department of Tropical Pathology, and Wellcome Trust Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 69:345-59. 2003
    ..7) than in NCM patients (median = 6.9) (P = 0.042). The degree of sequestration of P. falciparum-infected erythrocytes in cerebral microvessels is quantitatively associated with pre-mortem coma...
  78. ncbi request reprint Down-regulation of tight junction mRNAs in human endothelial cells co-cultured with Plasmodium falciparum-infected erythrocytes
    Pannapa Susomboon
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, 420 6 Ratchavithi Road, Bangkok 10400, Thailand
    Parasitol Int 55:107-12. 2006
    ..Although the mechanisms underlying these phenomena are not clear, our results suggest that PRBCs can alter expression of tight junction proteins in endothelial cells at the site of sequestration and thereby influence disease severity...
  79. ncbi request reprint Efficacy and tolerability of a sequential, artesunate suppository plus mefloquine, treatment of severe falciparum malaria
    S Looareesuwan
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Ann Trop Med Parasitol 89:469-75. 1995
    ..The combination is suitable as an alternative treatment for severe malaria, particularly in children. Further, large-scale studies are required...
  80. ncbi request reprint Contribution of humoral immunity to the therapeutic response in falciparum malaria
    M Mayxay
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 65:918-23. 2001
    ..7 [0.1-3.5] versus 2.6 [0.1-12.1]; P < 0.001). These results suggest that antimalarial antibodies may play an important supportive role in the therapeutic response to antimalarial drugs during acute falciparum malaria...
  81. ncbi request reprint Randomized trial of mefloquine alone and artesunate followed by mefloquine for the treatment of acute uncomplicated falciparum malaria
    S Looareesuwan
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Ann Trop Med Parasitol 88:131-6. 1994
    ..Only four patients who were treated with mefloquine alone had parasitaemia persisting to day 7 (RII), thus requiring alternative follow-up treatment.(ABSTRACT TRUNCATED AT 250 WORDS)..
  82. ncbi request reprint Poor efficacy of antimalarial biguanide-dapsone combinations in the treatment of acute, uncomplicated, falciparum malaria in Thailand
    P Wilairatana
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Thailand
    Ann Trop Med Parasitol 91:125-32. 1997
    ..The results demonstrate that short-course treatment with dapsone plus either proguanil or chlorproguanil is ineffective for the treatment of falciparum malaria in Thailand...
  83. pmc Can treatment of P. vivax lead to a unexpected appearance of falciparum malaria?
    D P Mason
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 32:57-63. 2001
    ..Both clinical results and features of the model suggest that such "hidden infections" may be quite common, and that the appearance of P. falciparum may be stimulated by treatment of P. vivax...
  84. ncbi request reprint Randomized dose-ranging study of the safety and efficacy of WR 238605 (Tafenoquine) in the prevention of relapse of Plasmodium vivax malaria in Thailand
    D S Walsh
    Department of Immunology, US Army Medical Component, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    J Infect Dis 180:1282-7. 1999
    ..Among patients treated with chloroquine only, there were 4 relapses (days 40, 43, 49, and 84). WR 238605 was safe, well tolerated, and effective in preventing P. vivax relapse...
  85. ncbi request reprint Paroxysm serum from a case of Plasmodium vivax malaria inhibits the maturation of P. falciparum schizonts in vitro
    Y Nagao
    Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Road, Bangkok, 10400 Thailand
    Ann Trop Med Parasitol 97:587-92. 2003
    ..vivax have been shown to inhibit the maturation of P. falciparum schizonts. The role of this mechanism in intra- and inter-specific competition is discussed...
  86. pmc New fixed-dose artesunate-mefloquine formulation against multidrug-resistant Plasmodium falciparum in adults: a comparative phase IIb safety and pharmacokinetic study with standard-dose nonfixed artesunate plus mefloquine
    S Krudsood
    Hospital for Tropical Disease, Bangkok, Thailand
    Antimicrob Agents Chemother 54:3730-7. 2010
    ..8 ng/ml. Fixed-dose AS-MQ was well tolerated, had pharmacokinetic (PK) profiles broadly similar to those of nonfixed AS plus MQ, and is a suitable replacement...
  87. ncbi request reprint Artemisinin antimalarials in pregnancy: a prospective treatment study of 539 episodes of multidrug-resistant Plasmodium falciparum
    R McGready
    Shoklo Malaria Research Unit, Mae Sot, Mahidol University, Bangkok, Thailand
    Clin Infect Dis 33:2009-16. 2001
    ..These results are reassuring, but further information about the safety of these valuable antimalarials in pregnancy is needed...
  88. ncbi request reprint Overview of clinical studies on artemisinin derivatives in Thailand
    S Looareesuwan
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Trans R Soc Trop Med Hyg 88:S9-11. 1994
    ..These drugs have proved rapidly effective and safe. Combination regimens with mefloquine have proved highly effective against multi-drug resistant Plasmodium falciparum infections. Both drugs are now licensed in Thailand...
  89. ncbi request reprint Tolerability of ivermectin in gnathostomiasis
    Valai Bussaratid
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Road, Bangkok 10400, Thailand
    Southeast Asian J Trop Med Public Health 36:644-9. 2005
    ..Ivermectin single dose, of 50,100, 150, and 200 microg/kg bodyweight, is considered safe in Thai patients. Future trials of ivermectin on human gnathostomiasis may be performed using dosages up to 200 microg/kg bodyweight...
  90. ncbi request reprint Short report: detection of Orientia tsutsugamushi in clinical samples by quantitative real-time polymerase chain reaction
    Tasawan Singhsilarak
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 72:640-1. 2005
    ..The assay was unreactive in all 12 individuals without scrub typhus infection. This is the first demonstration of a sensitive and specific real-time qPCR assay for human scrub typhus infection...
  91. pmc Comparison of oral artesunate and dihydroartemisinin antimalarial bioavailabilities in acute falciparum malaria
    Paul N Newton
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Antimicrob Agents Chemother 46:1125-7. 2002
    ..The mean antimalarial activity in terms of the bioavailability of DHA relative to that of artesunate did not differ significantly from 1, suggesting that DHA can be formulated to be an acceptable oral alternative to artesunate...
  92. ncbi request reprint Reduced levels of transforming growth factor-beta1, interleukin-12 and increased migration inhibitory factor are associated with severe malaria
    Sansanee C Chaiyaroj
    Department of Microbiology, Faculty of Science, Mahidol University, 10400, Bangkok, Thailand
    Acta Trop 89:319-27. 2004
    ..05). MIF, therefore, may play an important role in the local immune response to placental P. falciparum infection...
  93. ncbi request reprint An open, randomized trial of three-day treatment with artesunate combined with a standard dose of mefloquine divided over either two or three days, for acute, uncomplicated falciparum malaria
    U Silachamroon
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Road, Bangkok 10400, Thailand
    Southeast Asian J Trop Med Public Health 36:591-6. 2005
    ..These results suggest that a 3-day regimen of mefloquine administered with artesunate is effective and well tolerated. This practical regimen could improve patient compliance...
  94. ncbi request reprint Cytokines associated with pathology in the brain tissue of fatal malaria
    Y Maneerat
    Department of Tropical Pathology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 30:643-9. 1999
    ..No tissue-localized cytokine was observed in the brain of P. vivax infection or of the car accident control cases...
  95. ncbi request reprint Monotherapy with sodium artesunate for uncomplicated falciparum malaria in Thailand: a comparison of 5- and 7-day regimens
    S Looareesuwan
    Department of Clinical Tropical Medicine, Bangkok Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Thailand
    Acta Trop 67:197-205. 1997
    ..We conclude that 5- or 7-day regimens of sodium artesunate with a total dose of 1200-1600 mg are effective and safe in treating falciparum malaria acquired in Thailand...
  96. ncbi request reprint Prognostic significance of skin and subcutaneous fat sequestration of parasites in severe falciparum malaria
    P Wilairatana
    Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 31:203-12. 2000
    ..Results of the study suggest that histopathology and immunohistology of skin and subcutaneous fatty tissue may indicate prognostic severity of malaria and may be associated with focal accumulation of cytokines...
  97. ncbi request reprint The effects of quinine and artesunate treatment on plasma tumor necrosis factor levels in malaria-infected patients
    W Ittarat
    Department of Clinical Microscopy, Faculty of Medical Technology, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 30:7-10. 1999
    ..The rapid clearance of plasma TNF in quinine treated patients might be due to the drug's TNF-suppressive activity...
  98. ncbi request reprint Chloroquine sensitivity of Plasmodium vivax in Thailand
    S Looareesuwan
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Ann Trop Med Parasitol 93:225-30. 1999
    ..These data indicate that virtually all acute (i.e. blood-stage) P. vivax infections acquired in Thailand can still be successfully treated with chloroquine...
  99. ncbi request reprint A comparative clinical trial of combinations of dihydroartemisinin plus azithromycin and dihydroartemisinin plus mefloquine for treatment of multidrug resistant falciparum malaria
    S Krudsood
    Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 33:525-31. 2002
    ..01). We conclude that a combination of dihydroartemisnin and azithromycin was safe and effective and may be another interesting regimen of the treatment of uncomplicated multidrug resistant Plasmodium falciparum malaria in Thailand...
  100. ncbi request reprint A cross-sectional study of intestinal parasitic infections among schoolchildren in Nan Province, Northern Thailand
    J Waikagul
    Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 33:218-23. 2002
    ..Health promotion, by means of a school-based educational approach is recommended; regular check-ups should be implemented, and a continuos program of treatment should be considered...
  101. ncbi request reprint Effect of primaquine standard dose (15 mg/day for 14 days) in the treatment of vivax malaria patients in Thailand
    K Buchachart
    Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 32:720-6. 2001
    ..Daily doses of 15 mg of primaquine for 14 days following a full course of chloroquine when prescribed to Thai G6PD deficient patients where Mahidol variant is predominant, are relatively safe...