Pimlak Charoenkwan

Summary

Affiliation: Chiang Mai University
Country: Thailand

Publications

  1. ncbi request reprint Hematological and molecular characterization of beta-thalassemia/Hb Tak compound heterozygote
    Pimlak Charoenkwan
    Division of Hematology Oncology, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    Southeast Asian J Trop Med Public Health 34:415-9. 2003
  2. doi request reprint Cord blood screening for alpha-thalassemia and hemoglobin variants by isoelectric focusing in northern Thai neonates: correlation with genotypes and hematologic parameters
    Pimlak Charoenkwan
    Division of Hematology, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    Blood Cells Mol Dis 45:53-7. 2010
  3. ncbi request reprint Molecular and clinical features of Hb H disease in northern Thailand
    Pimlak Charoenkwan
    Division of Hematology, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    Hemoglobin 29:133-40. 2005
  4. doi request reprint Outcomes of thalassemia patients undergoing hematopoietic stem cell transplantation by using a standard myeloablative versus a novel reduced-toxicity conditioning regimen according to a new risk stratification
    Usanarat Anurathapan
    Department of Pediatrics, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Biol Blood Marrow Transplant 20:2066-71. 2014
  5. doi request reprint Effectiveness of the model for prenatal control of severe thalassemia
    Theera Tongsong
    Maharaj Nakorn Chiang Mai Hospital, Chiang Mai University, Chiang Mai, Thailand
    Prenat Diagn 33:477-83. 2013
  6. ncbi request reprint Hemoglobin E levels in double heterozygotes of hemoglobin E and SEA-type alpha-thalassemia
    Pimlak Charoenkwan
    Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    Southeast Asian J Trop Med Public Health 36:467-70. 2005
  7. pmc Heart Rate Variability for Early Detection of Cardiac Iron Deposition in Patients with Transfusion-Dependent Thalassemia
    Suchaya Silvilairat
    Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    PLoS ONE 11:e0164300. 2016
  8. ncbi request reprint Anemia and hydrops in a fetus with homozygous hemoglobin constant spring
    Pimlak Charoenkwan
    Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    J Pediatr Hematol Oncol 28:827-30. 2006
  9. doi request reprint A Longitudinal Study of Growth and Relation With Anemia and Iron Overload in Pediatric Patients With Transfusion-dependent Thalassemia
    Kwannapas Nokeaingtong
    Department of Pediatrics, Faculty of Medicine Department of Radiologic Technology, Faculty of Associated Medical Sciences Biomedical Engineering Center, Faculty of Engineering, Chiang Mai University, Chiang Mai, Thailand
    J Pediatr Hematol Oncol 38:457-62. 2016
  10. pmc Heart Rate Variability as an Alternative Indicator for Identifying Cardiac Iron Status in Non-Transfusion Dependent Thalassemia Patients
    Karn Wijarnpreecha
    Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Cardiac Electrophysiology Unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Center of Excellence in Cardiac Electrophysiology, Chiang Mai University, Chiang Mai, Thailand
    PLoS ONE 10:e0130837. 2015

Collaborators

Detail Information

Publications30

  1. ncbi request reprint Hematological and molecular characterization of beta-thalassemia/Hb Tak compound heterozygote
    Pimlak Charoenkwan
    Division of Hematology Oncology, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    Southeast Asian J Trop Med Public Health 34:415-9. 2003
    ..DNA sequencing study demonstrated an AC insertion at the terminal codon of the beta-globin gene. The clinical feature of polycythemia reflected a high oxygen affinity of Hb Tak...
  2. doi request reprint Cord blood screening for alpha-thalassemia and hemoglobin variants by isoelectric focusing in northern Thai neonates: correlation with genotypes and hematologic parameters
    Pimlak Charoenkwan
    Division of Hematology, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    Blood Cells Mol Dis 45:53-7. 2010
    ..IEF was a reliable method for neonatal cord blood screening for alpha-thalassemia and Hb variants...
  3. ncbi request reprint Molecular and clinical features of Hb H disease in northern Thailand
    Pimlak Charoenkwan
    Division of Hematology, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    Hemoglobin 29:133-40. 2005
    ....
  4. doi request reprint Outcomes of thalassemia patients undergoing hematopoietic stem cell transplantation by using a standard myeloablative versus a novel reduced-toxicity conditioning regimen according to a new risk stratification
    Usanarat Anurathapan
    Department of Pediatrics, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Biol Blood Marrow Transplant 20:2066-71. 2014
    ....
  5. doi request reprint Effectiveness of the model for prenatal control of severe thalassemia
    Theera Tongsong
    Maharaj Nakorn Chiang Mai Hospital, Chiang Mai University, Chiang Mai, Thailand
    Prenat Diagn 33:477-83. 2013
    ..The aim of the research was to determine effectiveness of the model for prenatal control in reducing new cases of severe thalassemia...
  6. ncbi request reprint Hemoglobin E levels in double heterozygotes of hemoglobin E and SEA-type alpha-thalassemia
    Pimlak Charoenkwan
    Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    Southeast Asian J Trop Med Public Health 36:467-70. 2005
    ..Our study confirms a lower Hb E level in double heterozygotes with Hb E and SEA-type alpha-thalassemia. Nevertheless, the difference does not provide sufficient discriminatory power for the reliable exclusion of alpha-thalassemia status...
  7. pmc Heart Rate Variability for Early Detection of Cardiac Iron Deposition in Patients with Transfusion-Dependent Thalassemia
    Suchaya Silvilairat
    Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    PLoS ONE 11:e0164300. 2016
    ..Heart rate variability (HRV) has been used to evaluate cardiac autonomic function and is depressed in cases of thalassemia. We evaluated whether HRV could be used as an indicator for early identification of cardiac iron deposition...
  8. ncbi request reprint Anemia and hydrops in a fetus with homozygous hemoglobin constant spring
    Pimlak Charoenkwan
    Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    J Pediatr Hematol Oncol 28:827-30. 2006
    ..Intrauterine transfusions were given which rendered a favorable outcome. This report demonstrates an unusual and serious in utero complication in a fetus with Hb CS/CS...
  9. doi request reprint A Longitudinal Study of Growth and Relation With Anemia and Iron Overload in Pediatric Patients With Transfusion-dependent Thalassemia
    Kwannapas Nokeaingtong
    Department of Pediatrics, Faculty of Medicine Department of Radiologic Technology, Faculty of Associated Medical Sciences Biomedical Engineering Center, Faculty of Engineering, Chiang Mai University, Chiang Mai, Thailand
    J Pediatr Hematol Oncol 38:457-62. 2016
    ..34 to -0.77; P<0.001) were significantly associated with short stature. In conclusion, short stature in patients with TDT is common and relates significantly with increasing age, male sex, hemoglobin level, and iron overload status. ..
  10. pmc Heart Rate Variability as an Alternative Indicator for Identifying Cardiac Iron Status in Non-Transfusion Dependent Thalassemia Patients
    Karn Wijarnpreecha
    Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Cardiac Electrophysiology Unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Center of Excellence in Cardiac Electrophysiology, Chiang Mai University, Chiang Mai, Thailand
    PLoS ONE 10:e0130837. 2015
    ..However, its direct correlation with cardiac iron accumulation has never been investigated. We investigated whether HRV can be used as an alternative indicator for early identification of cardiac iron deposition in thalassemia patients...
  11. ncbi request reprint Carboplatin and doxorubicin in treatment of pediatric osteosarcoma: a 9-year single institute experience in the Northern Region of Thailand
    Worawut Choeyprasert
    Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    Asian Pac J Cancer Prev 14:1101-6. 2013
    ..Carboplatin, a platinum-derived agent, is used as neoadjuvant chemotherapy for pediatric osteosarcoma because of its anti-tumor activity and had low toxicity as compared to cisplatin...
  12. pmc Pretransplant immunosuppression followed by reduced-toxicity conditioning and stem cell transplantation in high-risk thalassemia: a safe approach to disease control
    Usanarat Anurathapan
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Biol Blood Marrow Transplant 19:1259-62. 2013
    ..We conclude that this novel sequential immunoablative pretransplantation conditioning program is safe and effective for patients with high-risk class 3 thalassemia exhibiting additional comorbidities. ..
  13. doi request reprint Iron overload in non-transfusion-dependent thalassemia: association with genotype and clinical risk factors
    Adisak Tantiworawit
    Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand
    Int J Hematol 103:643-8. 2016
    ..001). In conclusion, the prevalence of hepatic iron overload is high in NTDT. Older age, lower hemoglobin level, and higher cumulative RBC transfusion are significant risk factors. SF and LIC show a significant positive correlation. ..
  14. doi request reprint Genotypes and phenotypes of protein S deficiency in Thai children with thromboembolism
    Patcharee Komwilaisak
    Faculty of Medicine, Department of Pediatrics, Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand
    Pediatr Blood Cancer . 2016
    ..PS mutations were identified in four patients: p.R355C, p.G336D, p.E67A, and p.N188KfsX9. p.N188KfsX9 is a novel mutation with less than 20% PS activity noted in heterozygotes...
  15. doi request reprint Use of cardiac markers for monitoring of doxorubixin-induced cardiotoxicity in children with cancer
    Yupada Pongprot
    Division of Pediatric Cardiology, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    J Pediatr Hematol Oncol 34:589-95. 2012
    ..40, P = 0.027). NT-pro-BNP is a sensitive test and has a moderate relationship with the LV systolic and diastolic function, thus making it a useful cardiac marker for the monitoring of early anthracycline cardiotoxicity...
  16. doi request reprint Adverse effects of imatinib in children with chronic myelogenous leukemia
    Worawut Choeyprasert
    Division of Pediatric Hematology Oncology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    Pediatr Int . 2016
    ..Potential side-effects regarding growth failure and bone metabolism have been reported but data are still scarce in pediatric CML...
  17. doi request reprint Hypercoagulable state as demonstrated by thromboelastometry in hemoglobin E/beta-thalassemia patients: Association with clinical severity and splenectomy status
    Rungrote Natesirinilkul
    Department of Pediatrics, Chiang Mai University, Chiang Mai 50200, Thailand Electronic address
    Thromb Res 140:125-31. 2016
    ..The objective was to describe the hemostatic and thromboelastometric changes in pediatric patients with E/β with different clinical severity, in comparison with healthy children as controls...
  18. doi request reprint Coinheritance of Hereditary Elliptocytosis and Deletional Hemoglobin H Disease
    Pimlak Charoenkwan
    Department of Pediatrics, Division of Hematology and Oncology Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    J Pediatr Hematol Oncol . 2017
    ..The red blood cells showed marked poikilocytosis and fragmentation. The parents were α-thalassemia carriers and the father had the typical red blood cell morphology of common hereditary elliptocytosis...
  19. doi request reprint The correlation of α-globin gene mutations and the XmnI polymorphism with clinical severity of Hb E/β-thalassemia
    Pimlak Charoenkwan
    Division of Hematology and Oncology, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    Hemoglobin 38:335-8. 2014
    ..071). This study demonstrates that coinheritance of α⁰-thal alleviates the degree of disease severity in Hb E/β-thal. All our patients with coinherited α⁰-thal have mild disease...
  20. ncbi request reprint Genotyping of beta thalassemia trait by high-resolution DNA melting analysis
    Rattika Saetung
    Department of Pediatrics, Faculty of Medcine, Chiang Mai University, Thailand
    Southeast Asian J Trop Med Public Health 44:1055-64. 2013
    ..Of the total cases, 85.8% of the mutations could be detected by primers B and C. The PCR-HRM method provides a rapid, simple and highly feasible strategy for mutation screening of beta thalassemia traits...
  21. ncbi request reprint Persistent hyperinsulinemic hypoglycemia of infancy associated with congenital neuroblastoma: a case report
    Prapai Dejkhamron
    Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    J Med Assoc Thai 93:745-8. 2010
    ..Spontaneous regression of neuroblastoma was suspected. The pathology of the pancreas was compatible with PHHI...
  22. doi request reprint Heart rate variability in beta-thalassemia patients
    Wasarut Rutjanaprom
    Cardiac Electrophysiology Unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    Eur J Haematol 83:483-9. 2009
    ..We evaluated HRV in TM patients and its relationship with hemodynamics and echocardiographic parameters during a 6-month follow-up...
  23. doi request reprint Health-Related Quality of Life in Adolescents with Thalassemia
    Nonglak Boonchooduang
    Division of Developmental and Behavioral Pediatrics, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    Pediatr Hematol Oncol 32:341-8. 2015
    ..For a better quality of life, thalassemia patients should be monitored for serum ferritin levels and treated for comorbidity as part of their comprehensive health care. ..
  24. doi request reprint Clinical course of dengue in patients with thalassaemia
    Rungrote Natesirinilkul
    Faculty of Medicine, Chiang Mai University, Thailand
    Paediatr Int Child Health 33:32-6. 2013
    ..Dengue and thalassaemia are prevalent in tropical regions. Thalassaemia patients with dengue present with atypical clinical manifestations and may experience more severe disease and complications...
  25. ncbi request reprint Tissue Doppler echocardiography reliably reflects severity of iron overload in pediatric patients with beta thalassemia
    Suchaya Silvilairat
    Division of Pediatric Cardiology, Chiang Mai University, Chiang Mai, Thailand
    Eur J Echocardiogr 9:368-72. 2008
    ..In clinical practice, serum ferritin is commonly used to assess the severity of iron overload. The aim of this study was to determine which Doppler findings correlated with serum ferritin...
  26. ncbi request reprint The effect of polymorphisms of MTHFR C677T, A1298C, MS A2756G and CBS 844ins68bp on plasma total homocysteine level and the risk of ischemic stroke in Thai children
    Nongnuch Sirachainan
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
    Thromb Res 122:33-7. 2008
  27. ncbi request reprint Recombinant-activated factor VII for control and prevention of hemorrhage in nonhemophilic pediatric patients
    Ampaiwan Chuansumrit
    Department of Pediatrics, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Blood Coagul Fibrinolysis 21:354-62. 2010
    ..These results support the safety and potential benefit of rFVIIa for control and prevention of hemorrhage in pediatric patients without congenital hemophilia...
  28. ncbi request reprint Mass spectrometry-based detection of hemoglobin E mutation by allele-specific base extension reaction
    Jason C H Tsang
    Department of Chemical Pathology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR
    Clin Chem 53:2205-9. 2007
    ..Systematic optimization resulted in an alternative protocol, the allele-specific base extension reaction (ASBER)...
  29. pmc MS analysis of single-nucleotide differences in circulating nucleic acids: Application to noninvasive prenatal diagnosis
    Chunming Ding
    Bioinformatics Program and Center for Advanced Biotechnology, Boston University, Boston, MA 02215, USA
    Proc Natl Acad Sci U S A 101:10762-7. 2004
    ..This analytical approach also will have implications for many other applications of circulating nucleic acids in areas such as oncology and transplantation...
  30. ncbi request reprint Significance of p53 expression in immature teratomas
    Pimlak Charoenkwan
    Division of Hematology Oncology, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada, M5G 1X8
    Pediatr Dev Pathol 5:499-507. 2002
    ..The finding of frequent p53-positive cells in immature teratoma should prompt a search for malignant elements within the tumor and affected patients should be followed closely for evidence of recurrence...