Kok Keng Tee

Summary

Publications

  1. doi request reprint Emerging and re-emerging viruses in Malaysia, 1997-2007
    Kok Keng Tee
    Department of Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
    Int J Infect Dis 13:307-18. 2009
  2. ncbi request reprint The evolving molecular epidemiology of HIV type 1 among injecting drug users (IDUs) in Malaysia
    Kok Keng Tee
    Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
    AIDS Res Hum Retroviruses 21:1046-50. 2005
  3. pmc Evolutionary genetics of human enterovirus 71: origin, population dynamics, natural selection, and seasonal periodicity of the VP1 gene
    Kok Keng Tee
    Laboratory of Molecular Virology and Epidemiology, AIDS Research Center, National Institute of Infectious Diseases, 1 23 1 Toyama, Shinjuku ku, Tokyo 162 8640, Japan
    J Virol 84:3339-50. 2010
  4. doi request reprint Reconstructing the epidemic history of HIV-1 circulating recombinant forms CRF07_BC and CRF08_BC in East Asia: the relevance of genetic diversity and phylodynamics for vaccine strategies
    Yutaka Takebe
    Laboratory of Molecular Virology and Epidemiology, AIDS Research Center, National Institute of Infectious Diseases, 1 23 1 Toyama, Shinjuku ku, Tokyo 162 8640, Japan
    Vaccine 28:B39-44. 2010
  5. doi request reprint Phylodynamic analysis of the dissemination of HIV-1 CRF01_AE in Vietnam
    Huanan Liao
    Laboratory of Molecular Virology and Epidemiology, AIDS Research Center, National Institute of Infectious Diseases, 1 23 1 Toyama, Shinjuku ku, Tokyo 162 8640, Japan
    Virology 391:51-6. 2009
  6. doi request reprint Explosive HIV-1 subtype B' epidemics in Asia driven by geographic and risk group founder events
    Yue Li
    Laboratory of Molecular Virology and Epidemiology, AIDS Research Center, National Institute of Infectious Diseases, 1 23 1 Toyama, Shinjuku ku, Tokyo 162 8640, Japan
    Virology 402:223-7. 2010
  7. pmc Temporal and spatial dynamics of human immunodeficiency virus type 1 circulating recombinant forms 08_BC and 07_BC in Asia
    Kok Keng Tee
    Laboratory of Molecular Virology and Epidemiology, AIDS Research Center, National Institute of Infectious Diseases, 1 23 1 Toyama, Shinjuku ku, Tokyo 162 8640, Japan
    J Virol 82:9206-15. 2008
  8. ncbi request reprint Short communication: low prevalence of genotypic drug resistance mutations among antiretroviral-naive HIV type 1 patients in Malaysia
    Kok Keng Tee
    Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
    AIDS Res Hum Retroviruses 22:121-4. 2006
  9. pmc Molecular diversity of HIV-1 among people who inject drugs in Kuala Lumpur, Malaysia: massive expansion of circulating recombinant form (CRF) 33_01B and emergence of multiple unique recombinant clusters
    Wei Zhen Chow
    Centre of Excellence for Research in AIDS CERiA, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    PLoS ONE 8:e62560. 2013
  10. pmc Isolation and characterization of a replication-competent molecular clone of an HIV-1 circulating recombinant form (CRF33_01B)
    Kok Keng Tee
    Laboratory of Molecular Virology and Epidemiology, AIDS Research Center, National Institute of Infectious Diseases, Shinjuku ku, Tokyo, Japan
    PLoS ONE 4:e6666. 2009

Collaborators

  • Kok Gan Chan
  • Yoke Fun Chan
  • Yue Li
  • Yun Fong Ngeow
  • Tommy Tsan Yuk Lam
  • Hong Shang
  • Munusamy Madhaiyan
  • Rosmawati Mohamed
  • Oon Tek Ng
  • Kah Ying Ng
  • Oliver Laeyendecker
  • Nguyen Tran Hien
  • C Y William Tong
  • Y Takebe
  • Ling Lu
  • Adeeba Kamarulzaman
  • Wei Zhen Chow
  • Wai Fong Yin
  • Jack Bee Chook
  • Yan Lue Lim
  • Robson Ee
  • Xiang Yong Oong
  • Delicia Yong
  • Lai Yee Ong
  • Maryam Nabiel Al-Khannaq
  • Nik Sherina Hanafi
  • Yong Kek Pang
  • Hui Ting Cheong
  • Choo Yee Yu
  • Haider Abdulrazzaq Abed Al-Darraji
  • Xueshan Xia
  • Yeat Mei Lee
  • Liang Jie Ng
  • Geik Yong Ang
  • Share Yuan Goh
  • Clayton Koh
  • Yean Kong Yong
  • Xin Yue Chan
  • Huanan Liao
  • Oliver G Pybus
  • Wenhua Zhao
  • Kah Yan How
  • Hazwan Abdul Halim
  • Lianghui Ji
  • Sheila Keating
  • Michael P Busch
  • Fread Anderios
  • Abdul Hamid Bon
  • Saad Ahmed Khan
  • Jian Woon Chen
  • Siti Sarah Nor'e
  • Nuruddin Muhammad Nor
  • Noor Hayaty Abu Kasim
  • Sin How Lim
  • Thiba Krishnan
  • Martin Choo
  • Woon Li Teo
  • Sasheela Sri La Sri Ponnampalavanar
  • Raja Iskandar Azwa
  • Siti Nur Humaira Razak
  • Sharifah Faridah Syed Omar
  • Malarvelli Soorya Prakasa
  • Nur Ezreen Syafina
  • Azureen Azmel
  • Chien Yi Chang
  • Siti Humaira Razak
  • Kar Wai Hong
  • Haider Al-Darraji
  • Saiki Hase
  • Rie Uenishi
  • Pham Hong Thang
  • Shigeru Kusagawa
  • Xiao Jie Li
  • Jing Yu
  • Muhammad Mahmood Mukhtar
  • Yixiong Lin
  • Xiaojie Li
  • Curt H Hagedorn
  • Qihan Li
  • Jianguo Wu
  • Yue Feng

Detail Information

Publications53

  1. doi request reprint Emerging and re-emerging viruses in Malaysia, 1997-2007
    Kok Keng Tee
    Department of Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
    Int J Infect Dis 13:307-18. 2009
    ..Finally, the HIV/AIDS epidemic has seen the emergence of an HIV-1 recombinant form (CRF33_01B) in HIV-infected individuals from various risk groups, with evidence of ongoing and rapid expansion...
  2. ncbi request reprint The evolving molecular epidemiology of HIV type 1 among injecting drug users (IDUs) in Malaysia
    Kok Keng Tee
    Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
    AIDS Res Hum Retroviruses 21:1046-50. 2005
    ..The results showed evidence of changing HIV-1 molecular epidemiology toward the predominance of CRF01_AE/B intersubtype recombinants among IDUs in Kuala Lumpur...
  3. pmc Evolutionary genetics of human enterovirus 71: origin, population dynamics, natural selection, and seasonal periodicity of the VP1 gene
    Kok Keng Tee
    Laboratory of Molecular Virology and Epidemiology, AIDS Research Center, National Institute of Infectious Diseases, 1 23 1 Toyama, Shinjuku ku, Tokyo 162 8640, Japan
    J Virol 84:3339-50. 2010
    ..We discuss the consequences of the evolutionary dynamics of EV-71 for vaccine design and compare its phylodynamic behavior with that of influenza virus...
  4. doi request reprint Reconstructing the epidemic history of HIV-1 circulating recombinant forms CRF07_BC and CRF08_BC in East Asia: the relevance of genetic diversity and phylodynamics for vaccine strategies
    Yutaka Takebe
    Laboratory of Molecular Virology and Epidemiology, AIDS Research Center, National Institute of Infectious Diseases, 1 23 1 Toyama, Shinjuku ku, Tokyo 162 8640, Japan
    Vaccine 28:B39-44. 2010
    ....
  5. doi request reprint Phylodynamic analysis of the dissemination of HIV-1 CRF01_AE in Vietnam
    Huanan Liao
    Laboratory of Molecular Virology and Epidemiology, AIDS Research Center, National Institute of Infectious Diseases, 1 23 1 Toyama, Shinjuku ku, Tokyo 162 8640, Japan
    Virology 391:51-6. 2009
    ..In the late 1980s, the virus spread to IDUs in Southern Vietnam and subsequently in the mid-1990s to IDUs further north. Our results indicate the northward dissemination of CRF01_AE during this time...
  6. doi request reprint Explosive HIV-1 subtype B' epidemics in Asia driven by geographic and risk group founder events
    Yue Li
    Laboratory of Molecular Virology and Epidemiology, AIDS Research Center, National Institute of Infectious Diseases, 1 23 1 Toyama, Shinjuku ku, Tokyo 162 8640, Japan
    Virology 402:223-7. 2010
    ....
  7. pmc Temporal and spatial dynamics of human immunodeficiency virus type 1 circulating recombinant forms 08_BC and 07_BC in Asia
    Kok Keng Tee
    Laboratory of Molecular Virology and Epidemiology, AIDS Research Center, National Institute of Infectious Diseases, 1 23 1 Toyama, Shinjuku ku, Tokyo 162 8640, Japan
    J Virol 82:9206-15. 2008
    ..This is the first phylodynamic study depicting the spatiotemporal dynamics of HIV/AIDS in East Asia...
  8. ncbi request reprint Short communication: low prevalence of genotypic drug resistance mutations among antiretroviral-naive HIV type 1 patients in Malaysia
    Kok Keng Tee
    Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
    AIDS Res Hum Retroviruses 22:121-4. 2006
    ....
  9. pmc Molecular diversity of HIV-1 among people who inject drugs in Kuala Lumpur, Malaysia: massive expansion of circulating recombinant form (CRF) 33_01B and emergence of multiple unique recombinant clusters
    Wei Zhen Chow
    Centre of Excellence for Research in AIDS CERiA, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    PLoS ONE 8:e62560. 2013
    ..The emergence of numerous previously unknown recombinant clades highlights the escalating genetic complexity of HIV-1 in the Southeast Asian region...
  10. pmc Isolation and characterization of a replication-competent molecular clone of an HIV-1 circulating recombinant form (CRF33_01B)
    Kok Keng Tee
    Laboratory of Molecular Virology and Epidemiology, AIDS Research Center, National Institute of Infectious Diseases, Shinjuku ku, Tokyo, Japan
    PLoS ONE 4:e6666. 2009
    ..Availability of a CRF33_01B molecular clone will be useful in facilitating the development of vaccine candidates that match the HIV-1 strains circulating in Southeast Asia...
  11. doi request reprint Estimating the date of origin of an HIV-1 circulating recombinant form
    Kok Keng Tee
    Laboratory of Molecular Virology and Epidemiology, AIDS Research Center, National Institute of Infectious Diseases, 1 23 1 Toyama, Shinjuku ku, Tokyo 162 8640, Japan
    Virology 387:229-34. 2009
    ..The proof-of-concept approach provides a new tool for the investigation of HIV molecular epidemiology and evolution...
  12. pmc Evolutionary history of HIV-1 subtype B and CRF01_AE transmission clusters among men who have sex with men (MSM) in Kuala Lumpur, Malaysia
    Kim Tien Ng
    Centre of Excellence for Research in AIDS CERiA, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    PLoS ONE 8:e67286. 2013
    ....
  13. ncbi request reprint Chronology of the HIV-1 CRF07_BC expansion in East Asia
    Kok Keng Tee
    Laboratory of Molecular Virology and Epidemiology, AIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan
    AIDS 22:156-8. 2008
    ..The separate introduction of CRF07_BC into Xinjiang occurred in 1992-1995. This study illustrates the temporal dynamics of CRF07_BC spread among IDU across east Asia...
  14. ncbi request reprint Identification of a novel circulating recombinant form (CRF33_01B) disseminating widely among various risk populations in Kuala Lumpur, Malaysia
    Kok Keng Tee
    Laboratory of Molecular Virology and Epidemiology, AIDS Research Center, National Institute of Infectious Diseases, 1 23 1 Toyama, Shinjuku ku, Tokyo 162 8640, Japan
    J Acquir Immune Defic Syndr 43:523-9. 2006
    ..6% (3/184) of study subjects, suggesting an ongoing recombination process in Malaysia. This new CRF seems to be bridging viral transmission between different risk populations in this country...
  15. pmc Diversity and Evolutionary Histories of Human Coronaviruses NL63 and 229E Associated with Acute Upper Respiratory Tract Symptoms in Kuala Lumpur, Malaysia
    Maryam Nabiel Al-Khannaq
    Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia AIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan School of Medicine, Yokohama City University, Kanagawa, Japan Department of Health Sciences, Faculty of Health and Life Sciences, Management and Science University, Selangor, Malaysia Department of Primary Care Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    Am J Trop Med Hyg 94:1058-64. 2016
    ..The study described the seasonality, molecular diversity, and evolutionary dynamics of human alphacoronavirus infections in a tropical region. ..
  16. pmc Performance of a Taqman Assay for Improved Detection and Quantification of Human Rhinovirus Viral Load
    Kim Tien Ng
    Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    Sci Rep 6:34855. 2016
    ..001). The availability of such assay is important to facilitate disease management, antiviral development, and infection control...
  17. pmc Genetic diversity, seasonality and transmission network of human metapneumovirus: identification of a unique sub-lineage of the fusion and attachment genes
    Wei Zhen Chow
    Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    Sci Rep 6:27730. 2016
    ..Our findings provide essential information for therapeutic research, prevention strategies, and disease outbreak monitoring of HMPV. ..
  18. pmc Genetic Characterization of a Novel HIV-1 Circulating Recombinant Form (CRF74_01B) Identified among Intravenous Drug Users in Malaysia: Recombination History and Phylogenetic Linkage with Previously Defined Recombinant Lineages
    Hui Ting Cheong
    Centre of Excellence for Research in AIDS CERiA, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    PLoS ONE 10:e0133883. 2015
    ..The characterization of the novel CRF74_01B is of considerable significance towards the understanding of the genetic diversity and population dynamics of HIV-1 circulating in the region. ..
  19. doi request reprint Identification of a novel second-generation circulating recombinant form (CRF48_01B) in Malaysia: a descendant of the previously identified CRF33_01B
    Yue Li
    Laboratory of Molecular Virology and Epidemiology, AIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan
    J Acquir Immune Defic Syndr 54:129-36. 2010
    ..Corroborating these results, Bayesian molecular clock analyses indicated that CRF48_01B emerged in approximately 2001, approximately approximately 8 years after the emergence of CRF33_01B...
  20. pmc Molecular epidemiology and evolutionary histories of human coronavirus OC43 and HKU1 among patients with upper respiratory tract infections in Kuala Lumpur, Malaysia
    Maryam Nabiel Al-Khannaq
    Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    Virol J 13:33. 2016
    ..Despite the worldwide circulation of human coronavirus OC43 (HCoV-OC43) and HKU1 (HCoV-HKU1), data on their molecular epidemiology and evolutionary dynamics in the tropical Southeast Asia region is lacking...
  21. doi request reprint Molecular diversity of HIV-1 and surveillance of transmitted drug resistance variants among treatment Naïve patients, 5 years after active introduction of HAART in Kuala Lumpur, Malaysia
    Lai Yee Ong
    Faculty of Medicine, Centre of Excellence for Research in AIDS CERiA, University of Malaya, Kuala Lumpur, Malaysia
    J Med Virol 86:38-44. 2014
    ..Owing to the high genetic diversity, continued molecular surveillance can identify the persistent emergence of HIV-1 URF and novel CRF with significant epidemiological impact...
  22. ncbi request reprint Emergence of HIV-1 CRF01_AE/B unique recombinant forms in Kuala Lumpur, Malaysia
    Kok Keng Tee
    Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
    AIDS 19:119-26. 2005
    ..To investigate the molecular epidemiology of HIV-1 and to screen for the emergence of intersubtype recombinants in Kuala Lumpur, Malaysia...
  23. pmc Identification and evolutionary dynamics of two novel human coronavirus OC43 genotypes associated with acute respiratory infections: phylogenetic, spatiotemporal and transmission network analyses
    Xiang Yong Oong
    Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
    Emerg Microbes Infect 6:e3. 2017
    ..Finally, a more consistent nomenclature system for non-recombinant and recombinant HCoV-OC43 lineages is proposed, taking into account genetic recombination as an important feature in HCoV evolution and classification...
  24. pmc Impact of HIV-1 Subtype on the Time to CD4+ T-Cell Recovery in Combination Antiretroviral Therapy (cART)-Experienced Patients
    Wei Zhen Chow
    Centre of Excellence for Research in AIDS CERiA, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    PLoS ONE 10:e0137281. 2015
    ..001) and viral load (P = .001) were important predictors for CD4+ T-cell recovery. Immunological recovery correlated significantly with female sex, baseline CD4+ T-cell counts and viral load but not subtype. ..
  25. ncbi request reprint Prevalence and pattern of drug resistance mutations among antiretroviral-treated HIV-1 patients with suboptimal virological response in Malaysia
    Kok Keng Tee
    Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
    Med Microbiol Immunol 195:107-12. 2006
    ..The prevalence of major drug resistance mutations among ARV-treated patients with detectable VL is high in Kuala Lumpur. Genotypic drug resistance testing is therefore important for monitoring patients experiencing ARV regimen failure...
  26. pmc Genome Sequences of Two Multidrug-Resistant Proteus mirabilis Strains Harboring CTX-M-65 Isolated from Malaysia
    Choo Yee Yu
    Division of Genetics and Molecular Biology, Institute of Biological Sciences, University of Malaya, Kuala Lumpur, Malaysia
    Genome Announc 4:. 2016
    ..mirabilis strains, isolated from urine samples in Malaysia, that harbored a CTX-M-type extended-spectrum β-lactamase-encoding gene, as well as a repertoire of other antimicrobial-resistant determinants...
  27. pmc Genome Anatomy of Streptococcus parasanguinis Strain C1A, Isolated from a Patient with Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Reveals Unusual Genomic Features
    Kok Gan Chan
    Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia
    Genome Announc 3:. 2015
    ..parasanguinis C1A, isolated from a patient diagnosed with an acute exacerbation of chronic obstructive pulmonary disease. Several genes that might be associated with pathogenesis are also described. ..
  28. doi request reprint Complete genome sequence of Serratia fonticola DSM 4576 T, a potential plant growth promoting bacterium
    Yan Lue Lim
    Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia
    J Biotechnol 214:43-4. 2015
    ..This genome sequence is valuable for functional genomics and ecological studies which are related to PGP and biocontrol activities. ..
  29. doi request reprint Complete genome of Pandoraea pnomenusa RB-38, an oxalotrophic bacterium isolated from municipal solid waste landfill site
    Yan Lue Lim
    Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia
    J Biotechnol 214:83-4. 2015
    ..pnomenusa RB38 in which an oxalate utilization pathway was identified. The genome analysis suggested the potential of this strain as an effective biocontrol agent against oxalate-producing phytopathogens. ..
  30. doi request reprint Complete genome sequence of Pandoraea thiooxydans DSM 25325(T), a thiosulfate-oxidizing bacterium
    Delicia Yong
    Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    J Biotechnol 217:51-2. 2016
    ..Here, we present the first complete genome of P. thiooxydans DSM 25325(T). Several genes involved in thiosulfate oxidation and biodegradation of aromatic compounds were identified. ..
  31. pmc Molecular detection of HIV-1 subtype B, CRF01_AE, CRF33_01B, and newly emerging recombinant lineages in Malaysia
    Jack Bee Chook
    Centre of Excellence for Research in AIDS CERiA, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia AIDS Research Center, National Institute of Infectious Diseases, Toyama, Shinjuku ku, Tokyo, Japan Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia
    Am J Trop Med Hyg 92:507-12. 2015
    ..The newly developed real-time PCR assay offers a rapid and cost-effective alternative for large-scale molecular epidemiological surveillance for HIV-1. ..
  32. pmc Cross-border sexual transmission of the newly emerging HIV-1 clade CRF51_01B
    Hui Ting Cheong
    Centre of Excellence for Research in AIDS CERiA, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    PLoS ONE 9:e111236. 2014
    ..Understanding the cross-border transmission of HIV-1 involving sexual networks is crucial for effective intervention strategies in the region. ..
  33. pmc Whole-Genome Analysis of Quorum-Sensing Burkholderia sp. Strain A9
    Kok Gan Chan
    Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia
    Genome Announc 3:. 2015
    ..In this work, we present the whole genome of Burkholderia sp. strain A9, which enables the discovery of its N-acyl homoserine lactone synthase gene. ..
  34. pmc Insights of biosurfactant producing Serratia marcescens strain W2.3 isolated from diseased tilapia fish: a draft genome analysis
    Xin Yue Chan
    Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia
    Gut Pathog 5:29. 2013
    ..In this study, for the first time, the genome sequences of S. marcescens strain W2.3 were sequenced using the Illumina MiSeq platform...
  35. pmc Pandoraea sp. Strain E26: Discovery of Its Quorum-Sensing Properties via Whole-Genome Sequence Analysis
    Kok Gan Chan
    Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia
    Genome Announc 3:. 2015
    ..strain E26 isolated from a former landfill site, sequenced by the Illumina MiSeq platform. This genome sequence will be useful to further understand the quorum-sensing system of this isolate. ..
  36. pmc Epidemiological and Evolutionary Dynamics of Influenza B Viruses in Malaysia, 2012-2014
    Xiang Yong Oong
    Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    PLoS ONE 10:e0136254. 2015
    ..This study describes the evolution of influenza B viruses in Malaysia and highlights the importance of continuous surveillance for better vaccination policy in this region...
  37. doi request reprint Complete genome sequence of Serratia multitudinisentens RB-25(T), a novel chitinolytic bacterium
    Yan Lue Lim
    Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia
    J Biotechnol 207:32-3. 2015
    ..To our knowledge, this is the first report of the complete genome sequence of this novel isolate and its chitinase gene discovery. ..
  38. pmc A newly emerging HIV-1 recombinant lineage (CRF58_01B) disseminating among people who inject drugs in Malaysia
    Wei Zhen Chow
    Centre of Excellence for Research in AIDS CERiA, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    PLoS ONE 9:e85250. 2014
    ....
  39. pmc Genome sequences of a novel HIV-1 CRF53_01B identified in Malaysia
    Wei Zhen Chow
    Centre of Excellence for Research in AIDS, Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    J Virol 86:11398-9. 2012
    ..The genome sequences may contribute to HIV-1 molecular surveillance and future vaccine development in the region...
  40. pmc Characterization and Comparative Overview of Complete Sequences of the First Plasmids of Pandoraea across Clinical and Non-clinical Strains
    Delicia Yong
    Department of Medical Microbiology, Faculty of Medicine, University of Malaya Kuala Lumpur, Malaysia
    Front Microbiol 7:1606. 2016
    ..Additionally, genes conferring virulence and antibiotic resistance were identified amongst the plasmids. The observed features in the plasmids shed light on the Pandoraea spp. as opportunistic pathogens...
  41. pmc Extensive Genetic Diversity of HIV-1 in Incident and Prevalent Infections among Malaysian Blood Donors: Multiple Introductions of HIV-1 Genotypes from Highly Prevalent Countries
    Wei Zhen Chow
    Centre of Excellence for Research in AIDS CERiA, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    PLoS ONE 11:e0161853. 2016
    ....
  42. doi request reprint Chania multitudinisentens gen. nov., sp. nov., an N-acyl-homoserine-lactone-producing bacterium in the family Enterobacteriaceae isolated from landfill site soil
    Robson Ee
    1 Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia
    Int J Syst Evol Microbiol 66:2297-304. 2016
    ..Strain RB-25T represents a novel species of a new genus, for which the name Chaniamultitudinisentens gen. nov., sp. nov. is proposed. The type strain is RB-25T (=DSM 28811T=LMG 28304T). ..
  43. pmc Draft Genome Sequence of Aeromonas caviae Strain L12, a Quorum-Sensing Strain Isolated from a Freshwater Lake in Malaysia
    Kok Gan Chan
    Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia
    Genome Announc 3:. 2015
    ..Here, we present the draft genome sequence of Aeromonas caviae strain L12, which shows quorum-sensing activity. The availability of this genome sequence is important to the research of the quorum-sensing regulatory system in this isolate. ..
  44. pmc Draft Genome Perspective of Staphylococcus saprophyticus Strain SU8, an N-Acyl Homoserine Lactone-Degrading Bacterium
    Kok Gan Chan
    Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia
    Genome Announc 3:. 2015
    ..Here we report the draft genome sequence of S. saprophyticus strain SU8 to further understand its quorum quenching abilities. ..
  45. pmc Genome sequence of a novel HIV-1 circulating recombinant form 54_01B from Malaysia
    Kim Tien Ng
    Centre of Excellence for Research in AIDS, Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    J Virol 86:11405-6. 2012
    ....
  46. pmc Transcriptome analysis of Pseudomonas aeruginosa PAO1 grown at both body and elevated temperatures
    Kok Gan Chan
    ISB Genetics and Molecular Biology, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia
    Peerj 4:e2223. 2016
    ..Because the RNA-seq can generate high throughput gene expression profiles, our work reveals many unanticipated genes with further work to be done exploring such genes products. ..
  47. pmc Complete Genome Sequence of Pluralibacter gergoviae FB2, an N-Acyl Homoserine Lactone-Degrading Strain Isolated from Packed Fish Paste
    Kok Gan Chan
    Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia
    Genome Announc 2:. 2014
    ..Hence, we report the first, complete genome of P. gergoviae sequenced using the Pacific Biosciences single-molecule, real-time (SMRT) platform. ..
  48. pmc Universal Primers for Detection and Sequencing of Hepatitis B Virus Genomes across Genotypes A to G
    Jack Bee Chook
    Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    J Clin Microbiol 53:1831-5. 2015
    ....
  49. pmc Quorum sensing activity of Citrobacter amalonaticus L8A, a bacterium isolated from dental plaque
    Share Yuan Goh
    Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia
    Sci Rep 6:20702. 2016
    ....
  50. pmc Phylodynamic profile of HIV-1 subtype B, CRF01_AE and the recently emerging CRF51_01B among men who have sex with men (MSM) in Singapore
    Kim Tien Ng
    Centre of Excellence for Research in AIDS CERiA, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
    PLoS ONE 8:e80884. 2013
    ..Our study provides the first insight on the phylodynamic profiles of HIV-1 subtype B, CRF01_AE and CRF51_01B viral strains circulating among MSM in Singapore. ..
  51. pmc Quorum sensing activity of Serratia fonticola strain RB-25 isolated from an ex-landfill site
    Robson Ee
    Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia
    Sensors (Basel) 14:5136-46. 2014
    ..This is the first report of the production of these AHLs in S. fonticola. ..
  52. doi request reprint Complete genome sequencing and phylogenetic analysis of HCV isolates from China reveals a new subtype, designated 6u
    Xueshan Xia
    Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunan, China
    J Med Virol 80:1740-6. 2008
    ..Because its designation does not meet the criteria described in the updated HCV nomenclature proposal, this "6u" isolate should be reclassified...
  53. pmc The unique HCV genotype distribution and the discovery of a novel subtype 6u among IDUs co-infected with HIV-1 in Yunnan, China
    Xueshan Xia
    Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, China
    J Med Virol 80:1142-52. 2008
    ..Routes of drug trafficking and the resulting high prevalence of HIV-1 infection may have contributed to this pattern of HCV genotype distribution...