Chiou Hwa Yuh

Summary

Affiliation: National Health Research Institutes
Country: Taiwan

Publications

  1. pmc Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathway
    Jeng Wei Lu
    Institute of Molecular and Genomic Medicine, National Health Research Institutes, Zhunan, Miaoli, Taiwan Department of Life Sciences, National Central University, Jhongli City, Taoyuan, Taiwan
    PLoS ONE 9:e85318. 2014
  2. pmc Complexity of cis-regulatory organization of six3a during forebrain and eye development in zebrafish
    Chung Hao Chao
    Division of Molecular and Genomic Medicine, National Health Research Institutes, Zhunan Town, Miaoli County, Taiwan
    BMC Dev Biol 10:35. 2010
  3. pmc Liver-specific expressions of HBx and src in the p53 mutant trigger hepatocarcinogenesis in zebrafish
    Jeng Wei Lu
    Institute of Molecular and Genomic Medicine, National Health Research Institutes, Zhunan, Miaoli, Taiwan Department of Life Sciences, National Central University, Jhongli City, Taoyuan, Taiwan
    PLoS ONE 8:e76951. 2013
  4. pmc Nestin is essential for zebrafish brain and eye development through control of progenitor cell apoptosis
    Hua Ling Chen
    Institute of Cellular and System Medicine, National Health Research Institutes, Zhunan, Taiwan
    PLoS ONE 5:e9318. 2010
  5. ncbi request reprint Hepatitis B virus X antigen and aflatoxin B1 synergistically cause hepatitis, steatosis and liver hyperplasia in transgenic zebrafish
    Jeng Wei Lu
    Institute of Molecular and Genomic Medicine, National Health Research Institutes, Zhunan, Miaoli, Taiwan Department of Life Sciences, National Central University, Jhongli City, Taoyuan, Taiwan
    Acta Histochem 115:728-39. 2013
  6. doi request reprint Functional analysis of the evolutionarily conserved cis-regulatory elements on the sox17 gene in zebrafish
    Tzu Min Chan
    Division of Molecular and Genomic Medicine, National Health Research Institutes, Taiwan, ROC
    Dev Biol 326:456-70. 2009
  7. doi request reprint Identification of the common regulators for hepatocellular carcinoma induced by hepatitis B virus X antigen in a mouse model
    Jeng Wei Lu
    Institute of Molecular and Genomic Medicine, National Health Research Institutes, Taiwan
    Carcinogenesis 33:209-19. 2012
  8. doi request reprint Developmental gene regulatory networks in the zebrafish embryo
    Tzu Min Chan
    Division of Molecular and Genomic Medicine, National Health Research Institute, Taiwan, Republic of China
    Biochim Biophys Acta 1789:279-98. 2009
  9. pmc Toll-like receptor 9 and 21 have different ligand recognition profiles and cooperatively mediate activity of CpG-oligodeoxynucleotides in zebrafish
    Da Wei Yeh
    Immunology Research Center, National Health Research Institutes, Miaoli 35053, Taiwan
    Proc Natl Acad Sci U S A 110:20711-6. 2013
  10. doi request reprint Liver development and cancer formation in zebrafish
    Jeng Wei Lu
    Institute of Molecular and Genomic Medicine, National Health Research Institutes, Taiwan, Republic of China
    Birth Defects Res C Embryo Today 93:157-72. 2011

Collaborators

  • Chau Ting Yeh
  • Jeng Fan Lo
  • Wei Chen Lee
  • Isao Matsuura
  • Miin Fu Chen
  • Grace S Shieh
  • Jeng Wei Lu
  • Horng Dar Wang
  • Wan Yu Yang
  • Chung Hao Chao
  • Tzu Min Chan
  • Shiow Lian Catherine Jin
  • Yueh Min Lin
  • Wen Fang Tseng
  • Hua Ling Chen
  • Shiu Feng Huang
  • Da Wei Yeh
  • Hsiao Chen Tu
  • Yu Hsia
  • Yu I Lin
  • Te Hsuan Jang
  • Yu Chang
  • Il Chi Chang
  • Liang Yu Shih
  • Ya Ting Chen
  • Yu Ting Chiu
  • Ming Wei Lai
  • Chung Yi Liao
  • Hong Dar Isaac Wu
  • Pen Heng Chang
  • Jen Leih Wu
  • Tsung Hsien Chuang
  • Yunping Luo
  • Jim Ray Chen
  • Rong Xiang
  • Su Mei Tsai
  • Yi Ling Liu
  • Guann Yi Yu
  • Yin Chiu Lo
  • Shih Feng Tsai
  • Ting Fen Tsai
  • Ko Wei Chang
  • Chao Chin Li
  • Yung Chun Hsiao
  • Chang Ben Huang
  • Kenneth K Wu
  • William Longabaugh
  • Hamid Bolouri
  • Yen Ju Yu
  • Shao Chin Hung

Detail Information

Publications12

  1. pmc Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathway
    Jeng Wei Lu
    Institute of Molecular and Genomic Medicine, National Health Research Institutes, Zhunan, Miaoli, Taiwan Department of Life Sciences, National Central University, Jhongli City, Taoyuan, Taiwan
    PLoS ONE 9:e85318. 2014
    ..In conclusion, our data suggest that EDN1 plays an important role in HCC progression by activating the PI3K/AKT pathway and is regulated by miR-1. ..
  2. pmc Complexity of cis-regulatory organization of six3a during forebrain and eye development in zebrafish
    Chung Hao Chao
    Division of Molecular and Genomic Medicine, National Health Research Institutes, Zhunan Town, Miaoli County, Taiwan
    BMC Dev Biol 10:35. 2010
    ..Though the function of Six3a as a crucial regulator of eye and forebrain development has been thoroughly investigated, the transcriptional regulation of six3a is not well understood...
  3. pmc Liver-specific expressions of HBx and src in the p53 mutant trigger hepatocarcinogenesis in zebrafish
    Jeng Wei Lu
    Institute of Molecular and Genomic Medicine, National Health Research Institutes, Zhunan, Miaoli, Taiwan Department of Life Sciences, National Central University, Jhongli City, Taoyuan, Taiwan
    PLoS ONE 8:e76951. 2013
    ..This phenomenon mimics human HCC formation and provides potential in vivo platforms for drug screening for therapies for human liver cancer. ..
  4. pmc Nestin is essential for zebrafish brain and eye development through control of progenitor cell apoptosis
    Hua Ling Chen
    Institute of Cellular and System Medicine, National Health Research Institutes, Zhunan, Taiwan
    PLoS ONE 5:e9318. 2010
    ..Nestin is expressed in neural progenitor cells (NPC) of developing brain. Despite its wide use as an NPC marker, the function of nestin in embryo development is unclear...
  5. ncbi request reprint Hepatitis B virus X antigen and aflatoxin B1 synergistically cause hepatitis, steatosis and liver hyperplasia in transgenic zebrafish
    Jeng Wei Lu
    Institute of Molecular and Genomic Medicine, National Health Research Institutes, Zhunan, Miaoli, Taiwan Department of Life Sciences, National Central University, Jhongli City, Taoyuan, Taiwan
    Acta Histochem 115:728-39. 2013
    ..Our data demonstrated a synergistic effect of AFB1 and HBx on the regulation of lipid metabolism related genes and cell cycle/division-related genes which might contribute to enhanced steatosis and hyperplasia at 5.75months. ..
  6. doi request reprint Functional analysis of the evolutionarily conserved cis-regulatory elements on the sox17 gene in zebrafish
    Tzu Min Chan
    Division of Molecular and Genomic Medicine, National Health Research Institutes, Taiwan, ROC
    Dev Biol 326:456-70. 2009
    ..This information provides new insight into the complexity of endoderm formation and serves as a valuable resource for the establishment of a complete endoderm gene regulatory network...
  7. doi request reprint Identification of the common regulators for hepatocellular carcinoma induced by hepatitis B virus X antigen in a mouse model
    Jeng Wei Lu
    Institute of Molecular and Genomic Medicine, National Health Research Institutes, Taiwan
    Carcinogenesis 33:209-19. 2012
    ....
  8. doi request reprint Developmental gene regulatory networks in the zebrafish embryo
    Tzu Min Chan
    Division of Molecular and Genomic Medicine, National Health Research Institute, Taiwan, Republic of China
    Biochim Biophys Acta 1789:279-98. 2009
    ..Comparison of GRNs' organizational motifs between different species will provide insights into developmental specification and its evolution. The online version of the zebrafish GRNs can be found at http://www.zebrafishGRNs.org...
  9. pmc Toll-like receptor 9 and 21 have different ligand recognition profiles and cooperatively mediate activity of CpG-oligodeoxynucleotides in zebrafish
    Da Wei Yeh
    Immunology Research Center, National Health Research Institutes, Miaoli 35053, Taiwan
    Proc Natl Acad Sci U S A 110:20711-6. 2013
    ..These results suggest that zebTLR9 and zebTLR21 cooperatively mediate the antimicrobial activities of CpG-ODN. Overall, this study provides a molecular basis for the activities of CpG-ODN in fish. ..
  10. doi request reprint Liver development and cancer formation in zebrafish
    Jeng Wei Lu
    Institute of Molecular and Genomic Medicine, National Health Research Institutes, Taiwan, Republic of China
    Birth Defects Res C Embryo Today 93:157-72. 2011
    ..A better understanding of liver development may aid in the development of new diagnostic and therapeutic approaches to liver cancer...
  11. doi request reprint An evolutionarily conserved kernel of gata5, gata6, otx2 and prdm1a operates in the formation of endoderm in zebrafish
    Wen Fang Tseng
    Institute of Molecular and Genomic Medicine, National Health Research Institutes, Zhunan Town, Miaoli County 350, Taiwan, ROC
    Dev Biol 357:541-57. 2011
    ..This is the first direct evidence for evolutionarily conserved endoderm specification across echinoderms and vertebrates...
  12. pmc Identification of transforming hepatitis B virus S gene nonsense mutations derived from freely replicative viruses in hepatocellular carcinoma
    Shiu Feng Huang
    Institute of Molecular and Genomic Medicine, National Health Research Institutes, Miaoli, Taiwan Department of Pathology, Chang Gung Memorial Hospital, Taoyuan, Taiwan Department of Pathology, Tzu Chi General Hospital, Taipei Branch, Tzu Chi University School of Medicine, Hualien, Taiwan
    PLoS ONE 9:e89753. 2014
    ..Only HBV X gene and nonsense mutations of S gene (C-terminal truncation of HBV surface protein) have been demonstrated to have transforming activity. Whether they play a significant role in hepatocarcinogenesis is still uncertain...