Fu Sung Lo

Summary

Affiliation: Chang Gung Memorial Hospital
Country: Taiwan

Publications

  1. doi request reprint Noonan syndrome caused by germline KRAS mutation in Taiwan: report of two patients and a review of the literature
    Fu Sung Lo
    Department of Pediatrics, Division of Pediatric Endocrinology, Chang Gung Memorial Hospital, Chung Gung University College of Medicine, Kweishan, Taoyuan, Taiwan
    Eur J Pediatr 168:919-23. 2009
  2. ncbi request reprint Auxological, clinical and MRI findings in Taiwanese children with growth hormone deficiency
    Fu Sung Lo
    Department of Pediatrics, National Taiwan University Hospital, Taiwan
    J Pediatr Endocrinol Metab 17:1519-26. 2004
  3. ncbi request reprint Clinical features of type 1 diabetic children at initial diagnosis
    Fu Sung Lo
    Division of Endocrinology, Chang Gung Children Hospital, Taoyuan, Taiwan
    Acta Paediatr Taiwan 45:218-23. 2004
  4. ncbi request reprint Two novel PHEX mutations in Taiwanese patients with X-linked hypophosphatemic rickets
    Fu Sung Lo
    Department of Pediatrics, Division of Endocrinology, Chang Gung Children Hospital, Kweishan, Taoyuan, Taiwan
    Nephron Physiol 103:p157-63. 2006
  5. ncbi request reprint Metabolic disorders in children and adolescents with type 2 diabetes mellitus
    Chi Yu Huang
    Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan
    Acta Paediatr Taiwan 47:187-91. 2006
  6. doi request reprint Association of an IL-4 gene haplotype with Graves disease in children: experimental study and meta-analysis
    Yann Jinn Lee
    Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan
    Hum Immunol 72:256-61. 2011
  7. ncbi request reprint Thyroid function in children with newly diagnosed type 1 diabetes mellitus
    Chao Hsu Lin
    Department of Pediatrics, Mackay Memorial Hospital, No 92, Sec 2, Chung Shan North Road, Taipei 10449, Taiwan
    Acta Paediatr Taiwan 44:145-9. 2003
  8. ncbi request reprint Polymorphism in the transmembrane region of the major histocompatibility complex class I chain-related gene A: association of five GCT repetitions with Graves' disease in children
    Fu Sung Lo
    Department of Pediatrics, Chang Gung Children s Hospital, Tao Yuang, Taiwan
    Thyroid 13:839-43. 2003
  9. ncbi request reprint Mutational analysis of PTPN11 gene in Taiwanese children with Noonan syndrome
    Chia Sui Hung
    Division of Pediatric Endocrinology, Chang Gung Children s Hospital, Taoyuan, Taiwan
    J Formos Med Assoc 106:169-72. 2007
  10. doi request reprint The IL18 gene and Hashimoto thyroiditis in children
    Chi Yu Huang
    Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan
    Hum Immunol 74:120-4. 2013

Collaborators

  • Luan Yin Chang
  • Shih Ming Jung
  • Marie Lin
  • Huei Shyong Wang
  • Shih Hsiang Chen
  • San Ging Shu
  • Pa Chun Wang
  • Tseng tong Kuo
  • Hsien Hsiung Lee
  • Che Ming Wu
  • Chao Hsing Yeh
  • Yann Jinn Lee
  • Chi Yu Huang
  • Wei Hsin Ting
  • Chao Hsu Lin
  • Yang Hau Van
  • Chia Sui Hung
  • Yi Lei Wu
  • Hsin Jung Li
  • Chiung Ling Lin
  • Wei Fang Chen
  • Chia Ching Chen
  • Ju Li Lin
  • Hsin Fu Liu
  • Chiao Fan Chiu
  • Shu Li Lee
  • Tzu Yang Chang
  • Wen Shan Lin
  • Ya Ping Lien
  • Ying Hua Huang
  • Bing Fu Shih
  • An Mei Wang
  • Kai Chieh Chan
  • Chen Mei Hung
  • Shuan Pei Lin
  • Mei Chyn Chao
  • Suei Tsau Tsai
  • Chi Wen Chang
  • Chen Chung Chu
  • Ming Ren Chen
  • Hsing Jung Li
  • Horng Woei Yang
  • Min Hua Tseng
  • Min hui Yang
  • Chao Hung Wang
  • Ming Chou Chiang
  • Bi Wen Cheng
  • Jainn Jim Lin
  • Chon In Chan
  • Ming Nan Chien
  • Bai Hsiun Chen
  • Ruey Hsia Wang
  • Stone Yang
  • Shin Lin Shih
  • Hung Chun Chen
  • Wen Yu Tsai
  • Jeng Daw Tsai
  • Hui Pin Hsiao
  • Daw Yang Hwang
  • Hui Wen Chan
  • Wan Ling Ho
  • Yau Yau Wai
  • Wen Ling Guo
  • Chi Kai Chen
  • Takakuni Tanizawa
  • Ya Ting Chang
  • Zen Chong Wang
  • Yuan Chieh Yeh
  • Chia Jung Chan
  • Iou Jih Hung
  • Jeng Chang Chen
  • Yi Li Shih
  • Hsun Hui Sui
  • Ting Chao
  • Fu Yuan Huang
  • Ching Cheng Tsang
  • Ching Wen Dang
  • Hsin An Kao
  • Chen Sheng Hwang
  • Shiu Feng Huang
  • Huoli Chuang
  • Chih Cheng Luo
  • Jer Nan Lin
  • Ching Horng Lai

Detail Information

Publications33

  1. doi request reprint Noonan syndrome caused by germline KRAS mutation in Taiwan: report of two patients and a review of the literature
    Fu Sung Lo
    Department of Pediatrics, Division of Pediatric Endocrinology, Chang Gung Memorial Hospital, Chung Gung University College of Medicine, Kweishan, Taoyuan, Taiwan
    Eur J Pediatr 168:919-23. 2009
    ..In conclusion, this investigation demonstrates that KRAS mutations are the cause in a minority of cases of Chinese patients with Noonan syndrome in Taiwan...
  2. ncbi request reprint Auxological, clinical and MRI findings in Taiwanese children with growth hormone deficiency
    Fu Sung Lo
    Department of Pediatrics, National Taiwan University Hospital, Taiwan
    J Pediatr Endocrinol Metab 17:1519-26. 2004
    ..Meticulous evaluation of auxological, clinical and MRI findings can help evaluation of the severity of hypopituitarism and facilitate appropriate treatment in children with GHD...
  3. ncbi request reprint Clinical features of type 1 diabetic children at initial diagnosis
    Fu Sung Lo
    Division of Endocrinology, Chang Gung Children Hospital, Taoyuan, Taiwan
    Acta Paediatr Taiwan 45:218-23. 2004
    ..Young age at diabetes onset and preceding febrile illness may provoke severe DKA. High alertness is necessary for prompt diagnosis and management...
  4. ncbi request reprint Two novel PHEX mutations in Taiwanese patients with X-linked hypophosphatemic rickets
    Fu Sung Lo
    Department of Pediatrics, Division of Endocrinology, Chang Gung Children Hospital, Kweishan, Taoyuan, Taiwan
    Nephron Physiol 103:p157-63. 2006
    ..The disease is caused by mutations in the PHEX gene (phosphate-regulating gene with homologies to endopeptidases on the X-chromosome) located at Xp22.1. To date, a variety of PHEX mutations have been identified in these patients...
  5. ncbi request reprint Metabolic disorders in children and adolescents with type 2 diabetes mellitus
    Chi Yu Huang
    Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan
    Acta Paediatr Taiwan 47:187-91. 2006
    ..It is the leading type of newly diagnosed diabetes in Taiwan among school children. T2DM is associated with metabolic syndrome in adults, so we tried to find out if these metabolic disorders are present in children...
  6. doi request reprint Association of an IL-4 gene haplotype with Graves disease in children: experimental study and meta-analysis
    Yann Jinn Lee
    Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan
    Hum Immunol 72:256-61. 2011
    ..Our study showed an association between the IL-4 gene and GD in children, but only using a haplotype-based method, suggesting that this might be a better approach than evaluating individual SNPs...
  7. ncbi request reprint Thyroid function in children with newly diagnosed type 1 diabetes mellitus
    Chao Hsu Lin
    Department of Pediatrics, Mackay Memorial Hospital, No 92, Sec 2, Chung Shan North Road, Taipei 10449, Taiwan
    Acta Paediatr Taiwan 44:145-9. 2003
    ..We suggest that thyroid function tests should be restricted to those patients suspected of having thyroid disorders at the initial diagnosis of type 1 diabetes...
  8. ncbi request reprint Polymorphism in the transmembrane region of the major histocompatibility complex class I chain-related gene A: association of five GCT repetitions with Graves' disease in children
    Fu Sung Lo
    Department of Pediatrics, Chang Gung Children s Hospital, Tao Yuang, Taiwan
    Thyroid 13:839-43. 2003
    ..12; 95% CI = 1.59-2.82; p = 1.9 x 10(-7); pc = 9.5 x 10(-7)). This study demonstrates that MICA allele A5 confers the risk for Graves' disease...
  9. ncbi request reprint Mutational analysis of PTPN11 gene in Taiwanese children with Noonan syndrome
    Chia Sui Hung
    Division of Pediatric Endocrinology, Chang Gung Children s Hospital, Taoyuan, Taiwan
    J Formos Med Assoc 106:169-72. 2007
    ..In conclusion, this study provides further support that PTPN11 mutations are responsible for Noonan syndrome in Taiwanese patients...
  10. doi request reprint The IL18 gene and Hashimoto thyroiditis in children
    Chi Yu Huang
    Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan
    Hum Immunol 74:120-4. 2013
    ..76; 95% CI, 1.24-2.49; Pc, 0.0049). We concluded that the IL18 gene was associated with HT in children. The rs187238C allele and CT haplotype conferred a risk of HT...
  11. pmc Association of Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) Gene Polymorphisms with Autoimmune Thyroid Disease in Children and Adults: Case-Control Study
    Wei Hsin Ting
    Department of Pediatrics, MacKay Children s Hospital, Taipei, Taiwan
    PLoS ONE 11:e0154394. 2016
    ..92). Our results showed that CTLA4 was associated with both GD and HD and played an equivalent role in both adult and pediatric GD in Han Chinese population. ..
  12. ncbi request reprint Primitive neuroectodermal tumor of the brain in a girl with Turner syndrome diagnosed after 4 years of growth hormone therapy
    Shih Hsiang Chen
    Division of Hematology and Oncology, Department of Medicine, Chang Gung Children s Hospital, 5 7 Fushing Street, Gueishan, Taoyuan, Taiwan
    Eur J Pediatr 165:344-5. 2006
  13. ncbi request reprint The CBLB gene and Graves' disease in children
    Chia Ching Chen
    Department of Pediatrics, Chiayi Christian Hospital, Chiayi, Taiwan
    J Pediatr Endocrinol Metab 18:1119-26. 2005
    ..This study demonstrates that the C/T polymorphism in exon 10 of the CBLB gene is not associated with Graves' disease in children...
  14. ncbi request reprint Insulin resistance in obese adolescents
    Hsing Jung Li
    Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan
    Acta Paediatr Taiwan 46:61-6. 2005
    ..8% of the degree of acanthosis nigricans (P<0.0001). Acanthosis nigricans thus may be a marker of insulin resistance and should be carefully looked for in obese adolescents...
  15. doi request reprint High resolution melting analysis for mutation detection for PTPN11 gene: applications of this method for diagnosis of Noonan syndrome
    Fu Sung Lo
    Division of Pediatric Endocrinology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    Clin Chim Acta 409:75-7. 2009
    ..Molecular diagnosis is useful for differential diagnosis. PTPN11 gene mutation is the most common mutation associated with NS and hence is a suitable target for molecular diagnostics...
  16. ncbi request reprint Clinical and laboratory findings at initial diagnosis in pediatric Graves' disease in Taiwan
    Chia Sui Hung
    Division of Pediatric Endocrinology and Metabolism, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung Children s Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
    Acta Paediatr Taiwan 47:77-82. 2006
    ..An awareness of symptoms is necessary for prompt diagnosis and management of Graves' disease because the disease can seriously interfere with children's growth and development...
  17. ncbi request reprint Pituitary apoplexy due to prolactinoma in a Taiwanese boy: patient report and review of the literature
    Min hui Yang
    Division of Endocrinology, Chang Gung Children s Hospital, Taoyuan, Taiwan
    J Pediatr Endocrinol Metab 16:1301-5. 2003
    ..Brain MRI is preferred for diagnosis. Dopaminergic agonists should be given if residual tumor or recurrence of prolactinoma is found after transsphenoidal surgery...
  18. doi request reprint Effect of growth hormone therapy on Taiwanese children with growth hormone deficiency
    Ying Hua Huang
    Department of Pediatrics, Chang Gung Memorial Hospital, Chung Gung University College of Medicine, Taoyuan, Taiwan
    J Formos Med Assoc 111:355-63. 2012
    ..Human growth hormone (GH) has been successfully used in children with GH deficiency (GHD). However, there are few published data on the effect of GH in Taiwanese children with GHD...
  19. pmc Mutations in pseudohypoparathyroidism 1a and pseudopseudohypoparathyroidism in ethnic Chinese
    Yi Lei Wu
    Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan Department of Pediatrics, Changhua Christian Hospital, Changhua, Taiwan
    PLoS ONE 9:e90640. 2014
    ..Mutation c.840-2A>G destroyed a spice acceptor site and caused exon skipping. Regular monitoring and adjustment in therapy are mandatory to achieve optimal therapeutic effects and avoid nephrolithiasis in patients with PHP1A. ..
  20. doi request reprint Hodgkin's lymphoma in a patient with Noonan syndrome with germ-line PTPN11 mutations
    Fu Sung Lo
    Department of Pediatrics, Chang Gung Memorial Hospital, Chung Gung University College of Medicine, Taoyuan, Taiwan
    Int J Hematol 88:287-90. 2008
    ..Mutational analysis of PTPN11 gene in cancer cells and understanding how SHP-2 contributes to oncogenesis will provide new insight into the pathogenesis of Hodgkin's lymphoma...
  21. ncbi request reprint Clinical and laboratory characteristics of type 1 diabetes in children and adolescents: experience from a medical center
    Wei Hsin Ting
    Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan
    Acta Paediatr Taiwan 48:119-24. 2007
    ..We developed a checklist of all symptoms of T1D reported in the literature and compared the completeness of the recording of symptoms at initial presentation before and after the checklist was adopted...
  22. ncbi request reprint Novel point mutations in complete androgen insensitivity syndrome with incomplete m├╝llerian regression: two Taiwanese patients
    Yang Hau Van
    Division of Endocrinology, Department of Paediatrics, Chang Gung Children s Hospital, 5 Fu Shing Street, Kweishan, 333 Taoyuan, Taiwan
    Eur J Pediatr 162:781-4. 2003
    ..Both patients received bilateral gonadectomy and inguinal hernia repair. The excised gonads proved to be testes with incomplete regression of the m├╝llerian structures...
  23. ncbi request reprint Coexistence of megaloblastic anemia and iron deficiency anemia in a young woman with chronic lymphocytic thyroiditis
    Shih Hsiang Chen
    Division of Pediatric Hematology Oncology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Chang Gung Children s Hospital, Taoyuan, Taiwan
    Int J Hematol 84:238-41. 2006
    ..After intramuscular injections of hydroxycobalamine 100 microg daily for 10 days, and monthly later, her blood counts returned to normal...
  24. doi request reprint Otologic and audiologic features of ethnic Chinese patients with Turner syndrome in Taiwan
    Kai Chieh Chan
    Division of Otology, Department of Otolaryngology Head and Neck Surgery, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
    J Formos Med Assoc 111:94-100. 2012
    ..We report these features and possible causative factors for hearing loss in ethnic Chinese TS patients in Taiwan...
  25. ncbi request reprint Association of CT60 polymorphism of the CTLA4 gene with Graves' disease in Taiwanese children
    Suei Tsau Tsai
    Department of Pediatrics, Taiwan Adventist Hospital, Taipei, Taiwan
    J Pediatr Endocrinol Metab 21:665-72. 2008
    ..The CTLA4 gene is involved in the activity of T cells...
  26. doi request reprint Nonketotic Hyperglycinemia of Infants in Taiwan
    Chiao Fan Chiu
    Department of Pediatrics, Chang Gang Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
    Pediatr neonatol 57:420-426. 2016
    ..1058+3A>C, in the intron 7 of the glycine decarboxylase (GLDC) gene. Furthermore, this study aimed to delineate the estimated incidence and clinical characteristics of NKH in the Taiwanese population...
  27. doi request reprint Predictors of Glycemic Control in Adolescents of Various Age Groups With Type 1 Diabetes
    Shu Li Lee
    1MSN, RN, Instructor, College of Nursing, Kaohsiung Medical University, and Doctoral Student, School of Nursing, Kaohsiung Medical University 2MD, MS, Attending Physician, Division of Endocrinology, Department of Pediatrics, Chang Gung Memorial Hospital 3MD, Attending Physician, Division of Endocrinology, Department of Pediatrics, Mackay Memorial Hospital 4MD, PhD, Attending Physician, Department of Pediatrics, Kaohsiung Medical University Hospital 5PhD, RN, Professor, College of Nursing, Kaohsiung Medical University
    J Nurs Res 23:271-9. 2015
    ..However, research has rarely addressed this issue, particularly in the context of Asian populations...
  28. doi request reprint Moyamoya disease in two patients with Noonan-like syndrome with loose anagen hair
    Fu Sung Lo
    Division of Pediatric Endocrinology and Genetics, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan
    Am J Med Genet A 167:1285-8. 2015
    ..Mutations in SHOC2 have been reported to underlie NSLH. In this paper, we describe two individuals with NSLH who also have moyamoya disease and in whom heterozygous germline mutation in SHOC2 was found...
  29. ncbi request reprint Pheochromocytoma presenting as stroke in two Taiwanese children
    Yang Hau Van
    Division of Endocrinology, Chang Gung Children s Hospital, Taoyuan, Taiwan
    J Pediatr Endocrinol Metab 15:1563-7. 2002
    ..They have been free from hypertension for 4 years (patient 1) and 2 years (patient 2)...
  30. ncbi request reprint Isolated Langerhans cell histiocytosis of the thyroid in a female infant
    Chia Sui Hung
    Department of Pediatrics, Chang Gung Children s Hospital, Chung Gung University College of Medicine, Taoyuan, Taiwan
    Eur J Pediatr 166:1151-3. 2007
    ..In conclusion, isolated LCH of the thyroid is rare, and its diagnosis can be challenging for a clinician and typically requires appropriate awareness. Local excision is the treatment of choice, and prolonged follow-up is recommended...
  31. ncbi request reprint Low frequency of the CYP21A2 deletion in ethnic Chinese (Taiwanese) patients with 21-hydroxylase deficiency
    Hsien Hsiung Lee
    Department of Medical Research, Mackay Memorial Hospital, 45 Min Sheng Road, Tanshui 251, Taipei County, Taiwan
    Mol Genet Metab 93:450-7. 2008
    ....
  32. ncbi request reprint Adherence behaviours in Taiwanese children and adolescents with type 1 diabetes mellitus
    Chi Wen Chang
    School of Nursing, Chang Gung University, 5 Fu Shing Street, Taoyuan 333, Taiwan
    J Clin Nurs 16:207-14. 2007
    ..aims and objective: To describe the current non-adherence behaviours of Taiwanese children with type 1 diabetes mellitus...
  33. ncbi request reprint Duplication of 111 bases in exon 1 of the CYP21 gene is combined with deletion of CYP21P-C4B genes in steroid 21-hydroxylase deficiency
    Hsien Hsiung Lee
    King Car Food Industrial Co, Yuan Shan Research Institute, No 326 Yuan Shan Rd, Sec 2, Yuan Shan, Ilan 264, Taiwan, Republic of China
    Mol Genet Metab 79:214-20. 2003
    ..Possibly, the additional 111-base duplicated coding sequence may be generated by multiple intergenic recombinations, while there seems to be no relationship with deletion of the CYP21P-C4B regions...