Jim Young

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi Lipid profiles for antiretroviral-naive patients starting PI- and NNRTI-based therapy in the Swiss HIV cohort study
    Jim Young
    Institut für klinisehe Epidemiologie, Universitatsspital Basel, Basel, Switzerland
    Antivir Ther 10:585-91. 2005
  2. ncbi The clinical diagnosis of acute bacterial rhinosinusitis in general practice and its therapeutic consequences
    Jim Young
    Basel Institute for Clinical Epidemiology, University Hospital Basel, Hebelstrasse 10, CH 4031 Basel, Switzerland
    J Clin Epidemiol 56:377-84. 2003
  3. doi Renal function in patients with HIV starting therapy with tenofovir and either efavirenz, lopinavir or atazanavir
    Jim Young
    Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland
    AIDS 26:567-75. 2012
  4. pmc Examining assumptions regarding valid electronic monitoring of medication therapy: development of a validation framework and its application on a European sample of kidney transplant patients
    Kris Denhaerynck
    Institute of Nursing Science, University of Basel, Bernoullistrasse 28, 4056, Basel, Switzerland
    BMC Med Res Methodol 8:5. 2008
  5. doi Efficacy, tolerability and risk factors for virological failure of darunavir-based therapy for treatment-experienced HIV-infected patients: the Swiss HIV Cohort Study
    J Young
    Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland
    HIV Med 12:299-307. 2011
  6. doi Virological and immunological responses to efavirenz or boosted lopinavir as first-line therapy for patients with HIV
    Jim Young
    Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland
    Antivir Ther 14:771-9. 2009
  7. doi Hierarchical modeling gave plausible estimates of associations between metabolic syndrome and components of antiretroviral therapy
    Jim Young
    Basel Institute for Clinical Epidemiology, University Hospital Basel, Switzerland
    J Clin Epidemiol 62:632-41. 2009
  8. doi Antibiotics for adults with clinically diagnosed acute rhinosinusitis: a meta-analysis of individual patient data
    Jim Young
    Basel Institute for Clinical Epidemiology, University Hospital Basel, Basel, Switzerland
    Lancet 371:908-14. 2008
  9. ncbi Patients' expectations about the benefit of antibiotic treatment: lessons from a randomised controlled trial
    Jim Young
    Institut für Klinische Epidemiologie, Universitatsspital Basel, Switzerland
    Forsch Komplementarmed Klass Naturheilkd 12:347-9. 2005
  10. ncbi Occipitomental (Waters' view) radiographs from general practice: are they adequate?
    Jim Young
    Basel Institute for Clinical Epidemiology, Kantonsspital Basel, Switzerland
    Swiss Med Wkly 134:132-5. 2004

Detail Information

Publications27

  1. ncbi Lipid profiles for antiretroviral-naive patients starting PI- and NNRTI-based therapy in the Swiss HIV cohort study
    Jim Young
    Institut für klinisehe Epidemiologie, Universitatsspital Basel, Basel, Switzerland
    Antivir Ther 10:585-91. 2005
    ..We report on medium-term lipid profiles (up to 5 years) for antiretroviral-naive patients starting NNRTI- and PI-based HAART in the Swiss HIV Cohort Study...
  2. ncbi The clinical diagnosis of acute bacterial rhinosinusitis in general practice and its therapeutic consequences
    Jim Young
    Basel Institute for Clinical Epidemiology, University Hospital Basel, Hebelstrasse 10, CH 4031 Basel, Switzerland
    J Clin Epidemiol 56:377-84. 2003
    ..These contradictory results are a salutary reminder that diagnostic indicators need to be evaluated in terms of therapeutic consequences for the patient...
  3. doi Renal function in patients with HIV starting therapy with tenofovir and either efavirenz, lopinavir or atazanavir
    Jim Young
    Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland
    AIDS 26:567-75. 2012
    ....
  4. pmc Examining assumptions regarding valid electronic monitoring of medication therapy: development of a validation framework and its application on a European sample of kidney transplant patients
    Kris Denhaerynck
    Institute of Nursing Science, University of Basel, Bernoullistrasse 28, 4056, Basel, Switzerland
    BMC Med Res Methodol 8:5. 2008
    ..To assess external validity, we examined if there were indications that using EM affected the sample representativeness...
  5. doi Efficacy, tolerability and risk factors for virological failure of darunavir-based therapy for treatment-experienced HIV-infected patients: the Swiss HIV Cohort Study
    J Young
    Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland
    HIV Med 12:299-307. 2011
    ..We assessed the efficacy, tolerability and risk factors for virological failure of darunavir for treatment-experienced patients seen in clinical practice...
  6. doi Virological and immunological responses to efavirenz or boosted lopinavir as first-line therapy for patients with HIV
    Jim Young
    Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland
    Antivir Ther 14:771-9. 2009
    ..It is uncertain which therapy is more effective for patients starting therapy with an advanced infection...
  7. doi Hierarchical modeling gave plausible estimates of associations between metabolic syndrome and components of antiretroviral therapy
    Jim Young
    Basel Institute for Clinical Epidemiology, University Hospital Basel, Switzerland
    J Clin Epidemiol 62:632-41. 2009
    ..Hierarchical modeling has been proposed as a solution to the multiple exposure problem. We estimate associations between metabolic syndrome and different components of antiretroviral therapy using both conventional and hierarchical models...
  8. doi Antibiotics for adults with clinically diagnosed acute rhinosinusitis: a meta-analysis of individual patient data
    Jim Young
    Basel Institute for Clinical Epidemiology, University Hospital Basel, Basel, Switzerland
    Lancet 371:908-14. 2008
    ..We undertook a meta-analysis of randomised trials based on individual patients' data to assess whether common signs and symptoms can be used to identify a subgroup of patients who benefit from antibiotics...
  9. ncbi Patients' expectations about the benefit of antibiotic treatment: lessons from a randomised controlled trial
    Jim Young
    Institut für Klinische Epidemiologie, Universitatsspital Basel, Switzerland
    Forsch Komplementarmed Klass Naturheilkd 12:347-9. 2005
    ..Patient expectations may be an important component of a placebo effect, and yet few studies assess how patients' pre-existing expectations affect subsequent health outcomes...
  10. ncbi Occipitomental (Waters' view) radiographs from general practice: are they adequate?
    Jim Young
    Basel Institute for Clinical Epidemiology, Kantonsspital Basel, Switzerland
    Swiss Med Wkly 134:132-5. 2004
    ..With a radiograph that is hard to read the physician should act as if the disease is present or refer the radiograph to a consulting radiologist...
  11. ncbi Body fat changes among antiretroviral-naive patients on PI- and NNRTI-based HAART in the Swiss HIV cohort study
    Jim Young
    Institut für Klinische Epidemiologie, Universitatsspital Basel, Basel, Switzerland
    Antivir Ther 10:73-81. 2005
    ..Our objective is to show whether such associations are more or less likely for patients on non-nucleoside reverse transcriptase inhibitor (NNRTI)-based HAART...
  12. doi Procalcitonin-guided antibiotic use vs a standard approach for acute respiratory tract infections in primary care
    Matthias Briel
    Department of Internal Medicine, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland
    Arch Intern Med 168:2000-7; discussion 2007-8. 2008
    ..We consider whether antibiotic therapy guided by procalcitonin reduces the use of antibiotics without increasing the restrictions experienced by patients by more than 1 day...
  13. doi The prevalence of erectile dysfunction and its association with antiretroviral therapy in HIV-infected men: the Swiss HIV Cohort Study
    Qing Wang
    Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland
    Antivir Ther 18:337-44. 2013
    ..Here, we aimed to determine the prevalence of erectile dysfunction (ED) among HIV-infected men and its association with components of antiretroviral therapy...
  14. ncbi Shared-decision making in general practice: do patients with respiratory tract infections actually want it?
    Matthias Briel
    Basel Institute for Clinical Epidemiology, University Hospital Basel, Switzerland
    Swiss Med Wkly 137:483-5. 2007
    ..There is conflicting evidence on whether patients wish to be involved in medical decisions...
  15. ncbi Is unsafe sexual behaviour increasing among HIV-infected individuals?
    Tracy R Glass
    Basel Institute for Clinical Epidemiology, University Hospital Basel, Switzerland
    AIDS 18:1707-14. 2004
    ..The number of new diagnoses of HIV infection is rising in the northwestern hemisphere and it is becoming increasingly important to understand the mechanisms behind this trend...
  16. doi Randomized trial of a computerized coronary heart disease risk assessment tool in HIV-infected patients receiving combination antiretroviral therapy
    Heiner C Bucher
    Basel Institute for Clinical Epidemiology and Biostatistics, Basel, Switzerland
    Antivir Ther 15:31-40. 2010
    ..Computerized clinical decision support systems have been advocated to improve the management of patients at risk for CHD but it is unclear whether such systems reduce patients' risk for CHD...
  17. doi Virologic and immunologic responses in treatment-naive patients to ritonavir-boosted atazanavir or efavirenz with a common backbone
    Qing Wang
    Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland
    HIV Clin Trials 15:92-103. 2014
    ..Atazanavir boosted with ritonavir (ATV/r) and efavirenz (EFV) are both recommended as first-line therapies for HIV-infected patients. We compared the 2 therapies for virologic efficacy and immune recovery...
  18. pmc Stable partnership and progression to AIDS or death in HIV infected patients receiving highly active antiretroviral therapy: Swiss HIV cohort study
    Jim Young
    Basel Institute for Clinical Epidemiology, University Hospital Basel, Hebelstrasse 10, Basle, CH 4031, Switzerland
    BMJ 328:15. 2004
    ..To explore the association between a stable partnership and clinical outcome in HIV infected patients receiving highly active antiretroviral therapy (HAART)...
  19. pmc Transient detectable viremia and the risk of viral rebound in patients from the Swiss HIV Cohort Study
    Jim Young
    Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland
    BMC Infect Dis 15:382. 2015
    ..Blips above 500 copies/mL have been associated with subsequent viral rebound. It is not clear if this relationship still holds when measurements are made using newer more sensitive assays...
  20. pmc Pretreatment CD4 cell slope and progression to AIDS or death in HIV-infected patients initiating antiretroviral therapy--the CASCADE collaboration: a collaboration of 23 cohort studies
    Marcel Wolbers
    Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland
    PLoS Med 7:e1000239. 2010
    ..It is not known whether the rate of CD4 cell decline prior to therapy is related to prognosis and should, therefore, influence the decision on when to initiate cART...
  21. ncbi Communication training and antibiotic use in acute respiratory tract infections. A cluster randomised controlled trial in general practice
    Matthias Briel
    Basel Institute for Clinical Epidemiology, University Hospital Basel, Switzerland
    Swiss Med Wkly 136:241-7. 2006
    ..A cluster-randomised controlled trial in general practice..
  22. pmc Procalcitonin-guided antibiotic use versus a standard approach for acute respiratory tract infections in primary care: study protocol for a randomised controlled trial and baseline characteristics of participating general practitioners [ISRCTN73182671]
    Matthias Briel
    Basel Institute for Clinical Epidemiology, University Hospital Basel, CH 4031 Basel, Switzerland
    BMC Fam Pract 6:34. 2005
    ..The aim of this trial is to compare a ProCT-guided antibiotic therapy with a standard approach based on evidence-based guidelines for patients with ARTI in primary care...
  23. doi Effect of Cumulating Exposure to Abacavir on the Risk of Cardiovascular Disease Events in Patients From the Swiss HIV Cohort Study
    Jim Young
    Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland Analysis Group Inc, Montreal, QC, Canada Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada Department of Medicine, Royal Victoria Hospital, McGill University Health Centre, Montreal, QC, Canada Division of Infectious Diseases, Regional Hospital of Lugano, Lugano, Switzerland Division of Infectious Diseases and Hospital Epidemiology, Cantonal Hospital St Gallen, St Gallen, Switzerland Division of Infectious Diseases, University Hospital Geneva, Geneva, Switzerland Division of Infectious Diseases, University Hospital Lausanne, Lausanne, Switzerland Department of Infectious Diseases, Bern University Hospital and University of Bern, Bern, Switzerland Division of Infectious Diseases and Hospital Epidemiology, University Hospital and University of Zurich, Zurich, Switzerland and Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland
    J Acquir Immune Defic Syndr 69:413-21. 2015
    ..There is concern that this association arises because of a channeling bias. Even if exposure is a risk, it is not clear how that risk changes as exposure cumulates...
  24. doi Assessing work ability--a cross-sectional study of interrater agreement between disability claimants, treating physicians, and medical experts
    Salome Dell-Kuster
    Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Hebelstrasse 10, CH 4051 Basel, Switzerland
    Scand J Work Environ Health 40:493-501. 2014
    ..It is unclear to what extent assessments of work ability differ between disability claimants, their treating physicians, and multidisciplinary medical expert teams...
  25. ncbi The value of a Waters' projection
    Jim Young
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 95:512-3; author reply 513. 2003
  26. ncbi Nonadherence with immunosuppressive drugs: U.S. compared with European kidney transplant recipients
    Kris Denhaerynck
    University of Basel, Switzerland
    Prog Transplant 16:206-14. 2006
    ..System factors increasingly are suggested as important yet understudied correlates of nonadherence...