Frank van Drogen
Affiliation: University of Lausanne
- MAP kinase cascades: scaffolding signal specificityFrank van Drogen
Swiss Institute for Experimental Cancer Research ISREC, Ch des Boveresses 155, 1066, Epalinges VD, Switzerland
Curr Biol 12:R53-5. 2002..Recent studies suggest that scaffold proteins provide local activation platforms that contribute to signal specificity by insulating different MAP kinase pathways...
- Cell cycle-dependent nuclear export of Cdh1p may contribute to the inactivation of APC/C(Cdh1)Malika Jaquenoud
Swiss Institute for Experimental Cancer Research ISREC, Chemin des Boveresses 155, 1066 Epalinges VD, Switzerland
EMBO J 21:6515-26. 2002..Taken together, these results suggest that phosphorylation-dependent nuclear export of Cdh1p by Msn5p contributes to efficient inactivation of APC/C(Cdh1)...
- Spa2p functions as a scaffold-like protein to recruit the Mpk1p MAP kinase module to sites of polarized growthFrank van Drogen
Swiss Institute for Experimental Cancer Research, Chemin des Boveresses 155, 1066, Epalinges VD, Switzerland
Curr Biol 12:1698-703. 2002..Taken together, these results suggest that Spa2p functions as a scaffold-like protein for the cell wall integrity pathway during polarized growth...
- Revealing protein dynamics by photobleaching techniquesFrank van Drogen
Department of Molecular Biology, The Scripps Research Institute, La Jolla, CA, USA
Methods Mol Biol 284:287-306. 2004..Here, we discuss these photobleaching fluorescent imaging techniques, illustrated with examples of these techniques applied to proteins of the Saccharomyces cerevisiae pheromone response MAPK pathway...