Giovanni Solinas

Summary

Affiliation: University of Fribourg
Country: Switzerland

Publications

  1. doi request reprint Molecular pathways linking metabolic inflammation and thermogenesis
    G Solinas
    Laboratory of Metabolic Stress Biology, Division of Physiology, Department of Medicine, University of Fribourg, Chemin du Musee 5, Fribourg, Switzerland
    Obes Rev 13:69-82. 2012
  2. doi request reprint JNK1 and IKKbeta: molecular links between obesity and metabolic dysfunction
    Giovanni Solinas
    Laboratory of Metabolic Stress Biology, Department of Medicine, Physiology, University of Fribourg, Chemin du Musee 5, CH 1700 Fribourg, Switzerland
    FASEB J 24:2596-611. 2010
  3. pmc A role for adipose tissue de novo lipogenesis in glucose homeostasis during catch-up growth: a Randle cycle favoring fat storage
    Helena Marcelino
    Department of Medicine Physiology, University of Fribourg, Fribourg, Switzerland
    Diabetes 62:362-72. 2013
  4. pmc Adipose tissue plasticity during catch-up fat driven by thrifty metabolism: relevance for muscle-adipose glucose redistribution during catch-up growth
    Serge Summermatter
    Department of Medicine Physiology, University of Fribourg, Fribourg, Switzerland
    Diabetes 58:2228-37. 2009
  5. pmc PI3Kγ within a nonhematopoietic cell type negatively regulates diet-induced thermogenesis and promotes obesity and insulin resistance
    Barbara Becattini
    Laboratory of Metabolic Stress Biology, Division of Physiology, Department of Medicine, University of Fribourg, CH 1700 Fribourg, Switzerland
    Proc Natl Acad Sci U S A 108:E854-63. 2011
  6. ncbi request reprint The direct effect of leptin on skeletal muscle thermogenesis is mediated by substrate cycling between de novo lipogenesis and lipid oxidation
    Giovanni Solinas
    Department of Medicine, Division of Physiology, University of Fribourg, Switzerland
    FEBS Lett 577:539-44. 2004
  7. ncbi request reprint JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity
    Giovanni Solinas
    Department of Medicine, University of Fribourg, Chemin du Musee 5, CH 1700 Fribourg, Switzerland
    Cell Metab 6:386-97. 2007
  8. ncbi request reprint Leptin directly stimulates thermogenesis in skeletal muscle
    Abdul G Dulloo
    Institute of Physiology, Department of Medicine, University of Fribourg, Chemin du Musee 5, CH 1700, Fribourg, Switzerland
    FEBS Lett 515:109-13. 2002
  9. doi request reprint High identification rates of endogenous neuropeptides from mouse brain
    Xiaozhe Zhang
    Department of Medicine, University of Fribourg, Fribourg, CH 1700, Switzerland
    J Proteome Res 11:2819-27. 2012

Collaborators

Detail Information

Publications9

  1. doi request reprint Molecular pathways linking metabolic inflammation and thermogenesis
    G Solinas
    Laboratory of Metabolic Stress Biology, Division of Physiology, Department of Medicine, University of Fribourg, Chemin du Musee 5, Fribourg, Switzerland
    Obes Rev 13:69-82. 2012
    ....
  2. doi request reprint JNK1 and IKKbeta: molecular links between obesity and metabolic dysfunction
    Giovanni Solinas
    Laboratory of Metabolic Stress Biology, Department of Medicine, Physiology, University of Fribourg, Chemin du Musee 5, CH 1700 Fribourg, Switzerland
    FASEB J 24:2596-611. 2010
    ..Understanding the molecular mechanisms by which JNK1 and IKKbeta mediate obesity-induced metabolic stress is likely to be of importance for the development of new treatments for a variety of obesity-associated diseases...
  3. pmc A role for adipose tissue de novo lipogenesis in glucose homeostasis during catch-up growth: a Randle cycle favoring fat storage
    Helena Marcelino
    Department of Medicine Physiology, University of Fribourg, Fribourg, Switzerland
    Diabetes 62:362-72. 2013
    ....
  4. pmc Adipose tissue plasticity during catch-up fat driven by thrifty metabolism: relevance for muscle-adipose glucose redistribution during catch-up growth
    Serge Summermatter
    Department of Medicine Physiology, University of Fribourg, Fribourg, Switzerland
    Diabetes 58:2228-37. 2009
    ..Our objective was to characterize the determinants of enhanced glucose utilization in adipose tissue during catch-up fat...
  5. pmc PI3Kγ within a nonhematopoietic cell type negatively regulates diet-induced thermogenesis and promotes obesity and insulin resistance
    Barbara Becattini
    Laboratory of Metabolic Stress Biology, Division of Physiology, Department of Medicine, University of Fribourg, CH 1700 Fribourg, Switzerland
    Proc Natl Acad Sci U S A 108:E854-63. 2011
    ..Thus, PI3Kγ is an unexpected but promising drug target for the treatment of obesity and its complications...
  6. ncbi request reprint The direct effect of leptin on skeletal muscle thermogenesis is mediated by substrate cycling between de novo lipogenesis and lipid oxidation
    Giovanni Solinas
    Department of Medicine, Division of Physiology, University of Fribourg, Switzerland
    FEBS Lett 577:539-44. 2004
    ..This substrate cycling linking glucose and lipid metabolism to thermogenesis provides a novel thermogenic mechanism by which leptin protects skeletal muscle from excessive fat storage and lipotoxicity...
  7. ncbi request reprint JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity
    Giovanni Solinas
    Department of Medicine, University of Fribourg, Chemin du Musee 5, CH 1700 Fribourg, Switzerland
    Cell Metab 6:386-97. 2007
    ..By contrast, Jnk1 removal from hematopoietic cells has no effect on adiposity but confers protection against HFD-induced insulin resistance by decreasing obesity-induced inflammation...
  8. ncbi request reprint Leptin directly stimulates thermogenesis in skeletal muscle
    Abdul G Dulloo
    Institute of Physiology, Department of Medicine, University of Fribourg, Chemin du Musee 5, CH 1700, Fribourg, Switzerland
    FEBS Lett 515:109-13. 2002
    ..These findings indicate that leptin has direct thermogenic effects in skeletal muscle, and that these effects require both the long form of leptin receptors and phosphatidylinositol 3-kinase signalling...
  9. doi request reprint High identification rates of endogenous neuropeptides from mouse brain
    Xiaozhe Zhang
    Department of Medicine, University of Fribourg, Fribourg, CH 1700, Switzerland
    J Proteome Res 11:2819-27. 2012
    ..This will advance our understanding of the roles of diverse peptides and their links in the brain functions...