A M Schoepfer
Affiliation: University Hospital
- Colonoscopic findings of symptomatic patients aged 50 to 80 years suggest that work-up of tumour suspicious symptoms hardly reduces cancer-induced mortalityAlain Schoepfer
Department of Gastroenterology, University Hospital Insel, Berne, Switzerland
Swiss Med Wkly 135:679-83. 2005..These data are of interest to validate the necessity of screening programmes, to define the target population and to interpret results of screening studies in asymptomatic people...
- Discriminating IBD from IBS: comparison of the test performance of fecal markers, blood leukocytes, CRP, and IBD antibodiesAlain M Schoepfer
Department of Gastroenterology, Inselspital University of Bern, Switzerland
Inflamm Bowel Dis 14:32-9. 2008..We aimed to determine the accuracy of fecal markers, C-reactive protein (CRP), blood leukocytes, and antibody panels for discriminating IBD from IBS and to define a "best test."..
- Phenotypic associations of Crohn's disease with antibodies to flagellins A4-Fla2 and Fla-X, ASCA, p-ANCA, PAB, and NOD2 mutations in a Swiss CohortAlain M Schoepfer
Department of Gastroenterology, Inselspital Bern University Hospital, Bern, Switzerland
Inflamm Bowel Dis 15:1358-67. 2009....
- Antibodies to flagellin indicate reactivity to bacterial antigens in IBS patientsA M Schoepfer
Department of Gastroenterology, Inselspital, Bern University Hospital, Bern, Switzerland
Neurogastroenterol Motil 20:1110-8. 2008..This observation supports the concept that immune reactivity to luminal antigens has a putative role in the development of IBS, at least in a subset of patients...
- [Chronic diarrhea: etiologies and diagnostic evaluation]A Schoepfer
Klinik fur Gastroenterologie, Inselspital, Bern
Praxis (Bern 1994) 97:495-500. 2008..The endoscopy is well established in the workup of chronic diarrhea. This article gives an overview about the main causes and mechanisms leading to chronic diarrhea and proposes an algorithm for the diagnostic evalution...
- Esophageal strictures in adult eosinophilic esophagitis: dilation is an effective and safe alternative after failure of topical corticosteroidsA M Schoepfer
Department of Gastroenterology, University of Bern Inselspital, Switzerland
Endoscopy 40:161-4. 2008..Bougienage led to prompt symptom relief. Apart from transient postprocedural odynophagia, no severe complications occurred. During the follow-up (mean 6 months; range 2 - 11 months), all patients enjoyed sustained treatment response...
- Accuracy of four fecal assays in the diagnosis of colitisAlain M Schoepfer
Department of Gastroenterology, University Hospital Inselspital, Bern, Switzerland
Dis Colon Rectum 50:1697-706. 2007....
- Quality of life: a potentially useful measure to indicate subclinical flares in Crohn diseaseR J A Cámara
Department of General Internal Medicine, Division of Psychosomatic Medicine, Inselspital, Bern University Hospital, Bern, Switzerland
Intern Med J 42:e145-51. 2012..If QoL measures were to be associated with intestinal inflammatory activity, they might be useful for early detection of subclinical flares...
- Corticosteroid-dependent eosinophilic oesophagitis: azathioprine and 6-mercaptopurine can induce and maintain long-term remissionPeter Netzer
Department of Gastroenterology, University of Berne, Berne, Switzerland
Eur J Gastroenterol Hepatol 19:865-9. 2007..Although systemic and topical corticosteroids are effective in treating EO, some patients develop corticosteroid dependency. Alternative therapeutic approaches that avoid corticosteroids are scarce...
- Anti-Saccharomyces cerevisiae mannan antibodies (ASCA) of Crohn's patients crossreact with mannan from other yeast strains, and murine ASCA IgM can be experimentally induced with Candida albicansThomas Schaffer
Department of Clinical Research, Division of Gastroenterology, University Hospital Bern, University of Bern, Bern, Switzerland
Inflamm Bowel Dis 13:1339-46. 2007..The present study aimed to determine crossreactivities of ASCA with cell wall mannans from other yeasts, including the opportunistic pathogen C. albicans, and to define the requirements for (crossreactive) ASCA in experimental mice...
- Partial overlap of anti-mycobacterial, and anti-Saccharomyces cerevisiae mannan antibodies in Crohn's diseaseStefan Muller
Department of Clinical Research, Division of Gastroenterology, University of Bern, Bern CH 3010, Switzerland
World J Gastroenterol 14:3650-61. 2008..To test whether humoral immune reaction against mycobacteria may play a role in anti-Saccharomyces cerevisiae antibodies (ASCA) generation in Crohn's disease (CD) and/or whether it correlates with clinical subtypes...
- Association of deficiency for mannan-binding lectin with anti-mannan antibodies in Crohn's disease: a family studyFrank Seibold
Division of Gastroenterology, Inselspital, University of Bern, Bern, Switzerland
Inflamm Bowel Dis 13:1077-82. 2007..MBL concentration depends on genetic polymorphisms. The aim of this study was to evaluate whether low MBL is related to ASCA production in healthy family members of CD patients...
- Herbal does not mean innocuous: ten cases of severe hepatotoxicity associated with dietary supplements from Herbalife productsAlain M Schoepfer
University Hospital of Bern, Gastroenterology Clinic, Bern, Switzerland
J Hepatol 47:521-6. 2007..Herbal agents are popular and perceived as safe because they are supposedly 'natural'. We report 10 cases of toxic hepatitis implicating Herbalife products...
- Galectin-3 modulates T cell activity and is reduced in the inflamed intestinal epithelium in IBDStefan Muller
Department of Clinical Research, Division of Gastroenterology, University Hospital, University of Bern, Switzerland
Inflamm Bowel Dis 12:588-97. 2006..The present study aims to determine galectin-3 expression in the normal and inflamed intestinal mucosa and to define its role in T cell activity...