Affiliation: University of Lausanne
- p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitmentSimona Saccani
Institute for Research in Biomedicine, Via Vela 6, CH 6501, Bellinzona, Switzerland
Nat Immunol 3:69-75. 2002..These results show that p38 plays an additional role in the induction of the inflammatory and immune response: the regulation of NF-kappa B recruitment to selected chromatin targets...
- Modulation of NF-kappaB activity by exchange of dimersSimona Saccani
Institute for Research in Biomedicine, Via Vela 6, CH6500 Bellinzona, Switzerland
Mol Cell 11:1563-74. 2003..Further, due to the insensitivity of p52/RelB to the NF-kappaB inhibitors, the IkappaBs, dimer exchange contributes to sustained activation of selected NF-kappaB targets in spite of the resynthesis of IkappaBalpha...
- Plastic downregulation of the transcriptional repressor BCL6 during maturation of human dendritic cellsSerafino Pantano
Institute for Research in Biomedicine, Via Vela 6, Bellinzona CH6500, Switzerland
Exp Cell Res 312:1312-22. 2006..By regulating the induction of several genes implicated in the immune response, including inflammatory cytokines, chemokines and survival genes, BCL6 may represent a pivotal modulator of the afferent branch of the immune response...