Andre R Miserez

Summary

Affiliation: University of Basel
Country: Switzerland

Publications

  1. pmc For debate: substituting placebo controls in long-term Alzheimer's prevention trials
    Rene Spiegel
    University Hospital Department of Geriatrics, Memory Clinic, Schanzenstrasse 55, CH 4031 Basel, Switzerland
    Alzheimers Res Ther 3:9. 2011
  2. ncbi Apolipoprotein E3Basel: new insights into a highly conserved protein region
    A R Miserez
    Department of Internal Medicine, University Hospital Bruderholz, Switzerland
    Eur J Clin Invest 33:677-85. 2003
  3. ncbi Sterol-regulatory element-binding protein (SREBP)-2 contributes to polygenic hypercholesterolaemia
    Andre R Miserez
    Cardiovascular Genetics, Institute of Biochemistry and Genetics, Department of Clinical Biological Sciences, University of Basel, Vesalgasse 1, Ch 4051, Basel, Switzerland
    Atherosclerosis 164:15-26. 2002
  4. ncbi Indinavir inhibits sterol-regulatory element-binding protein-1c-dependent lipoprotein lipase and fatty acid synthase gene activations
    Andre R Miserez
    Cardiovascular Genetics, Institute of Biochemistry and Genetics, Department of Clinical Biological Sciences, University of Basel, Basel, Switzerland
    AIDS 16:1587-94. 2002
  5. ncbi Processing of gene expression data generated by quantitative real-time RT-PCR
    Patrick Y Muller
    Research Group Cardiovascular Genetics, Institute of Biochemistry and Genetics, University of Basel, Switzerland
    Biotechniques 32:1372-4, 1376, 1378-9. 2002
  6. ncbi Molecular Biocomputing Suite: a word processor add-in for the analysis and manipulation of nucleic acid and protein sequence data
    P Y Muller
    Department of Clinical Biological Sciences, University of Basel, Switzerland
    Biotechniques 31:1306, 1308, 1310-3. 2001
  7. ncbi Statins induce differentiation and cell death in neurons and astroglia
    Pia März
    Institute of Physiology, University of Basel, CH 4056 Basel, Switzerland
    Glia 55:1-12. 2007
  8. ncbi Argyrophilic grain disease: molecular genetic difference to other four-repeat tauopathies
    Andre R Miserez
    Cardiovascular Genetics, Institute of Biochemistry and Genetics, Department of Clinical Biological Sciences, University of Basel, Basel, Switzerland
    Acta Neuropathol 106:363-6. 2003
  9. ncbi Large heterogeneity of mutations in the gene encoding the low-density lipoprotein receptor in subjects with familial hypercholesterolaemia
    Patrick Y Muller
    Department of Clinical Biological Sciences, Cardiovascular Genetics, Institute of Biochemistry and Genetics, University of Basel, Vesalgasse 1, 4051 Basel, Switzerland
    Atheroscler Suppl 5:1-5. 2004
  10. pmc Identification of mutations in the gene encoding sterol regulatory element binding protein (SREBP)-2 in hypercholesterolaemic subjects
    P Y Muller
    Cardiovascular Genetics, Department of Clinical Biological Sciences, Institute of Biochemistry and Genetics, University of Basel, Vesalgasse I, CH 4051 Basel, Switzerland
    J Med Genet 39:271-5. 2002

Collaborators

Detail Information

Publications12

  1. pmc For debate: substituting placebo controls in long-term Alzheimer's prevention trials
    Rene Spiegel
    University Hospital Department of Geriatrics, Memory Clinic, Schanzenstrasse 55, CH 4031 Basel, Switzerland
    Alzheimers Res Ther 3:9. 2011
    ..Forecasted outcomes are compared with outcomes observed on candidate drugs, thus replacing a concomitant placebo group...
  2. ncbi Apolipoprotein E3Basel: new insights into a highly conserved protein region
    A R Miserez
    Department of Internal Medicine, University Hospital Bruderholz, Switzerland
    Eur J Clin Invest 33:677-85. 2003
    ..Particular apolipoprotein E mutations have been also found to be associated with nephrologic, neurologic, and even ophthalmologic diseases. Hence, a continuously expanding role in biology is being attributed to this protein...
  3. ncbi Sterol-regulatory element-binding protein (SREBP)-2 contributes to polygenic hypercholesterolaemia
    Andre R Miserez
    Cardiovascular Genetics, Institute of Biochemistry and Genetics, Department of Clinical Biological Sciences, University of Basel, Vesalgasse 1, Ch 4051, Basel, Switzerland
    Atherosclerosis 164:15-26. 2002
    ....
  4. ncbi Indinavir inhibits sterol-regulatory element-binding protein-1c-dependent lipoprotein lipase and fatty acid synthase gene activations
    Andre R Miserez
    Cardiovascular Genetics, Institute of Biochemistry and Genetics, Department of Clinical Biological Sciences, University of Basel, Basel, Switzerland
    AIDS 16:1587-94. 2002
    ..A marker predicting this syndrome has been previously identified in the gene encoding the sterol-regulatory element-binding protein (SREBP)-1c, a regulator of triglycerides, cholesterol, insulin, and adipocytes...
  5. ncbi Processing of gene expression data generated by quantitative real-time RT-PCR
    Patrick Y Muller
    Research Group Cardiovascular Genetics, Institute of Biochemistry and Genetics, University of Basel, Switzerland
    Biotechniques 32:1372-4, 1376, 1378-9. 2002
    ....
  6. ncbi Molecular Biocomputing Suite: a word processor add-in for the analysis and manipulation of nucleic acid and protein sequence data
    P Y Muller
    Department of Clinical Biological Sciences, University of Basel, Switzerland
    Biotechniques 31:1306, 1308, 1310-3. 2001
    ..Its independence of sequence formats enables MBCS to be used as a pivotal application between other software tools for sequence analysis, manipulation, annotation, and editing...
  7. ncbi Statins induce differentiation and cell death in neurons and astroglia
    Pia März
    Institute of Physiology, University of Basel, CH 4056 Basel, Switzerland
    Glia 55:1-12. 2007
    ..We postulate that under these conditions signals provided by astrocytes, e.g., isoprenoids play a key role in neuronal survival...
  8. ncbi Argyrophilic grain disease: molecular genetic difference to other four-repeat tauopathies
    Andre R Miserez
    Cardiovascular Genetics, Institute of Biochemistry and Genetics, Department of Clinical Biological Sciences, University of Basel, Basel, Switzerland
    Acta Neuropathol 106:363-6. 2003
    ..These data suggest that a dysfunction of the tau protein in AgD-in contrast to other four-repeat tauopathies-may arise irrespective of the genetic background regarding the tau H1 or H2 haplotypes...
  9. ncbi Large heterogeneity of mutations in the gene encoding the low-density lipoprotein receptor in subjects with familial hypercholesterolaemia
    Patrick Y Muller
    Department of Clinical Biological Sciences, Cardiovascular Genetics, Institute of Biochemistry and Genetics, University of Basel, Vesalgasse 1, 4051 Basel, Switzerland
    Atheroscler Suppl 5:1-5. 2004
    ....
  10. pmc Identification of mutations in the gene encoding sterol regulatory element binding protein (SREBP)-2 in hypercholesterolaemic subjects
    P Y Muller
    Cardiovascular Genetics, Department of Clinical Biological Sciences, Institute of Biochemistry and Genetics, University of Basel, Vesalgasse I, CH 4051 Basel, Switzerland
    J Med Genet 39:271-5. 2002
    ..In summary, this is the first report of mutations in the human SREBP-2 gene to suggest that these and/or other mutations in this key regulator of cholesterol metabolism are associated with hypercholesterolaemia...
  11. ncbi A single-nucleotide polymorphism in the sterol-regulatory element-binding protein 1c gene is predictive of HIV-related hyperlipoproteinaemia
    A R Miserez
    Department of Clinical-Biological Sciences, University of Basel, Switzerland
    AIDS 15:2045-9. 2001
    ..A functional mutation linked to SREBP-1c-3'322C/G or messenger RNA conformation differences may explain our findings...
  12. ncbi RepGene: a spreadsheet template for the management of reporter gene assays
    P Y Muller
    University of Basel, Switzerland
    Biotechniques 30:1294-8. 2001
    ..The objectives of this spreadsheet template are the design of the transfection protocol, the coordination of the administration of test compounds, and the graphical presentation and statistical analysis of the results...