Valerie A McLin
Affiliation: University Hospital
- Recent advances in the molecular and genetic understanding of congenital gastrointestinal malformationsVéronique Dauvé
Departement de Pediatrie, Faculte de Medecine, Hôpitaux Universitaires de Genève et Universitè de Genève, Geneve, Switzerland
J Pediatr Gastroenterol Nutr 57:4-13. 2013..We review advances in the molecular and genetic understanding of gastrointestinal development using evidence from both mammalian and nonmammalian models. When appropriate, we highlight relevance and applicability to human disease...
- Blood pressure elevation in long-term survivors of pediatric liver transplantationV A McLin
Department of Pediatrics, University Hospitals Geneva, Switzerland
Am J Transplant 12:183-90. 2012..Pediatric LT patients show a high prevalence of elevated BP measurements 5 to 10 years following LT, which is related to age at LT, decreased cGFR and recent steroid use...
- The role of the visceral mesoderm in the development of the gastrointestinal tractValerie A McLin
Department of Pediatrics, Section of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine, Houston, Texas, USA
Gastroenterology 136:2074-91. 2009..In reviewing evidence from both mammalian and nonmammalian models, we reveal the important role of the visceral mesoderm in the ontogeny of the GI tract...
- Identification and gastrointestinal expression of Xenopus laevis FoxF2Valerie A McLin
Department of Pediatrics, Section of Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine, Houston, TX, USA
Int J Dev Biol 54:919-24. 2010..Here, we describe the cloning and expression pattern of XFoxF2 during embryonic development, metamorphosis and adulthood, and compare and contrast it to the expression of FoxF1 in Xenopus laevis and FoxF2 in mouse...
- Expression of complement components coincides with early patterning and organogenesis in Xenopus laevisValerie A McLin
Department of Pediatrics, Baylor College of Medicine BCM, Houston, Texas 77030, USA
Int J Dev Biol 52:1123-33. 2008..The expression patterns of these molecules suggest that these components of the complement system may have in Xenopus a so far undefined developmental role...
- Parental functioning improves the developmental quotient of pediatric liver transplant recipientsKlara M Posfay-Barbe
Department of Pediatrics, Children s Hospital of Geneva, University Hospitals of Geneva, 6 Rue Willy Donze, Geneva, Switzerland
Pediatr Transplant 17:355-61. 2013..03). Paternal performance scores were higher than maternal scores. Children transplanted after two yr of age suffer greater long-term deficits than those transplanted as infants...
- Molecular control of liver developmentValerie A McLin
Baylor College of Medicine, Texas Childrens Liver Center, 1102 Bates Street, Houston, TX 77006, USA
Clin Liver Dis 10:1-25, v. 2006..Understanding the molecular control of liver development should impact diagnosis and treatment of pediatric and adult liver diseases and aid in efforts to differentiate liver tissue in vitro for stem cell-based therapies...
- Complications of indwelling central venous catheters in pediatric liver transplant recipientsVladimir L Cousin
Pediatric Gastroenterology Unit, University Hospitals Geneva, Geneva, Switzerland
Pediatr Transplant 20:798-806. 2016..Children receiving technical variants may be more at risk of complications. By removing ICVC in a select number of patients at six months post-insertion, we might avoid as much as 60% of complications. ..
- Repression of Wnt/beta-catenin signaling in the anterior endoderm is essential for liver and pancreas developmentValerie A McLin
Cincinnati Children s Research Foundation, Department of Pediatrics, College of Medicine, University of Cincinnati, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
Development 134:2207-17. 2007..These results illustrate that turning Wnt signaling off and on in the correct temporal sequence is essential for organ formation, a finding that might directly impact efforts to differentiate liver and pancreas tissue from stem cells...
- Immune reconstitution inflammatory syndrome and solid organ transplant recipients: are children protected?Valerie A McLin
Department of Pediatrics, Children s Hospital of Geneva, University Hospitals of Geneva, Geneva, Switzerland
Pediatr Transplant 14:19-22. 2010..However, IRIS has to date not been reported in pediatric SOT recipients. Here we review what is known and speculated about the pathogenesis of IRIS and propose that children may be relatively protected from IRIS...
- Bile Ducts in Regenerative Liver Nodules of Alagille Patients Are Not the Result of Genetic MosaicismAnne Laure Rougemont
Department of Pathology, Sainte Justine Hospital, Montreal, Canada Division of Clinical Pathology, Geneva University Hospitals, Geneva, Switzerland Division of Gastroenterology, Hepatology and Nutrition, Sainte Justine Hospital, Montreal, Canada Pediatric Gastroenterology Unit, Geneva University Hospitals, Geneva, Switzerland Génétique Moléculaire, Pharmacogénétique et Hormonologie, Hopital Bicetre, Faculté de Médecine de Bicêtre, Universite Paris Sud, Paris, France Division of Pediatric Surgery, Geneva University Hospitals, Geneva, Switzerland
J Pediatr Gastroenterol Nutr 61:91-3. 2015..Thus, JAG1 mosaicism and differential haploinsufficiency do not explain the presence of bile ducts in centrally located regenerative nodules...
- Psycho-social outcome in liver transplanted children: beware of emotional self-assessment!Ana Maria Calinescu
Division of Pediatric Surgery, Department of Pediatrics, University Children s Hospital of Geneva, Geneva, Switzerland
Ital J Pediatr 38:37. 2012..We hypothesized that patients and their parents after LT report their psycho-social well-being too enthusiastically when enquired by their personal care takers...
- Complications of chronic liver diseaseAlexandra Tsouka
Department of Pediatrics, University Hospitals Geneva, 5, rue Willy Donze, 1205 Geneva, Switzerland
Clin Res Hepatol Gastroenterol 36:262-7. 2012..Nutritional assessment and management is the cornerstone of management. Consider immune dysfunction in everyday treatment decisions. Consider early heart-lung-brain involvement in transplant evaluation...
- Glomerular and tubular function following orthotopic liver transplantation in childrenValerie A McLin
Department of Pediatrics, University of Geneva Hospital, Geneva, Switzerland
Pediatr Transplant 9:512-9. 2005..The aims of this study were to examine glomerular and tubular function after orthotopic liver transplantation (OLT) in children, their correlation to CsA, and how they differed according to the underlying disease...
- Language and motor skills are impaired in infants with biliary atresia before transplantationSusan E Caudle
Psychology Service, Texas Children s Hospital and Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA
J Pediatr 156:936-40, 940.e1. 2010..To test the hypothesis that in very young patients with biliary atresia, cognitive deficits are apparent before transplantation...