C Lysakowski

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi request reprint Magnesium for the prevention and treatment of acute mountain sickness
    Lionel Dumont
    Neuroanaesthesia Unit, Division of Anaesthesiology, Department of Anaesthesiology, Pharmacology and Surgical Intensive Care, Geneva University Hospitals, Geneva, Switzerland
    Clin Sci (Lond) 106:269-77. 2004
  2. ncbi request reprint Impact of the intubation model on the efficacy of rocuronium during rapid sequence intubation: systematic review of randomized trials
    C Lysakowski
    Division of Anaesthesiology, University Hospitals of Geneva, Geneva, Switzerland
    Acta Anaesthesiol Scand 51:848-57. 2007
  3. ncbi request reprint Magnesium as an adjuvant to postoperative analgesia: a systematic review of randomized trials
    Christopher Lysakowski
    Division of Anesthesiology, Department Anesthesiology, Pharmacology and Intensive Care, Geneva University Hospitals, Geneva, Switzerland
    Anesth Analg 104:1532-9, table of contents. 2007
  4. ncbi request reprint Transcranial Doppler versus angiography in patients with vasospasm due to a ruptured cerebral aneurysm: A systematic review
    C Lysakowski
    Divisions of Anesthesiology, Neuroanesthesia Unit, Geneva University Hospitals, Geneva, Switzerland
    Stroke 32:2292-8. 2001
  5. doi request reprint Bispectral and spectral entropy indices at propofol-induced loss of consciousness in young and elderly patients
    C Lysakowski
    Division of Anaesthesiology, University Hospitals of Geneva, Rue Gabrielle Perret Gentil 4, CH 1211 Geneva 14, Switzerland
    Br J Anaesth 103:387-93. 2009
  6. ncbi request reprint Effect of magnesium, high altitude and acute mountain sickness on blood flow velocity in the middle cerebral artery
    Christopher Lysakowski
    Neuroanaesthesia Unit, Division of Anaesthesiology, Department of Anaesthesiology, Pharmacology and Surgical Intensive Care, Geneva University Hospitals, Geneva, Switzerland
    Clin Sci (Lond) 106:279-85. 2004
  7. ncbi request reprint The effect of cigarette smoking on the hypnotic efficacy of propofol
    C Lysakowski
    Division of Anaesthesiology, Department of Anaesthesiology, Pharmacology and Intensive Care, Geneva University Hospitals, Geneva, Switzerland
    Anaesthesia 61:826-31. 2006
  8. ncbi request reprint Effects of fentanyl, alfentanil, remifentanil and sufentanil on loss of consciousness and bispectral index during propofol induction of anaesthesia
    C Lysakowski
    Division of Anaesthesiology, Geneva University Hospitals, Switzerland
    Br J Anaesth 86:523-7. 2001
  9. doi request reprint Intravenous lidocaine has no impact on rocuronium-induced neuromuscular block. Randomised study
    C Czarnetzki
    Division of Anaesthesiology, Geneva University Hospitals, Geneva, Switzerland
    Acta Anaesthesiol Scand 56:474-81. 2012
  10. doi request reprint Time course of rocuronium-induced neuromuscular block after pre-treatment with magnesium sulphate: a randomised study
    C Czarnetzki
    Division of Anaesthesiology, University Hospitals of Geneva, CH 1211 Geneva 14, Switzerland
    Acta Anaesthesiol Scand 54:299-306. 2010

Detail Information

Publications20

  1. ncbi request reprint Magnesium for the prevention and treatment of acute mountain sickness
    Lionel Dumont
    Neuroanaesthesia Unit, Division of Anaesthesiology, Department of Anaesthesiology, Pharmacology and Surgical Intensive Care, Geneva University Hospitals, Geneva, Switzerland
    Clin Sci (Lond) 106:269-77. 2004
    ..05 (0.01-0.25)]. In conclusion, oral magnesium does not prevent AMS. In subjects with established AMS, intravenous magnesium reduces the severity of symptoms to some extent, but this effect is of no clinical importance...
  2. ncbi request reprint Impact of the intubation model on the efficacy of rocuronium during rapid sequence intubation: systematic review of randomized trials
    C Lysakowski
    Division of Anaesthesiology, University Hospitals of Geneva, Geneva, Switzerland
    Acta Anaesthesiol Scand 51:848-57. 2007
    ..Propofol-rocuronium is thought to be superior to thiopental-rocuronium for rapid sequence intubation (RSI). The role of the intubation model per se has never been investigated...
  3. ncbi request reprint Magnesium as an adjuvant to postoperative analgesia: a systematic review of randomized trials
    Christopher Lysakowski
    Division of Anesthesiology, Department Anesthesiology, Pharmacology and Intensive Care, Geneva University Hospitals, Geneva, Switzerland
    Anesth Analg 104:1532-9, table of contents. 2007
    ..Randomized trials have reached different conclusions as to whether magnesium is a useful adjuvant to postoperative analgesia...
  4. ncbi request reprint Transcranial Doppler versus angiography in patients with vasospasm due to a ruptured cerebral aneurysm: A systematic review
    C Lysakowski
    Divisions of Anesthesiology, Neuroanesthesia Unit, Geneva University Hospitals, Geneva, Switzerland
    Stroke 32:2292-8. 2001
    ..Our aim was to evaluate both the accuracy of TCD compared with angiography and its usefulness as a screening method in this setting...
  5. doi request reprint Bispectral and spectral entropy indices at propofol-induced loss of consciousness in young and elderly patients
    C Lysakowski
    Division of Anaesthesiology, University Hospitals of Geneva, Rue Gabrielle Perret Gentil 4, CH 1211 Geneva 14, Switzerland
    Br J Anaesth 103:387-93. 2009
    ..Since the EEG is changing with increasing age, we investigated the impact of advanced age on BIS, SE, and RE indices during induction...
  6. ncbi request reprint Effect of magnesium, high altitude and acute mountain sickness on blood flow velocity in the middle cerebral artery
    Christopher Lysakowski
    Neuroanaesthesia Unit, Division of Anaesthesiology, Department of Anaesthesiology, Pharmacology and Surgical Intensive Care, Geneva University Hospitals, Geneva, Switzerland
    Clin Sci (Lond) 106:279-85. 2004
    ..s(-1) before compared with 67 +/- 16 cm.s(-1) after rescue medication; P=0.79). MCAv was increased in subjects who received magnesium, but was not affected by exposure to high altitude or by severe AMS...
  7. ncbi request reprint The effect of cigarette smoking on the hypnotic efficacy of propofol
    C Lysakowski
    Division of Anaesthesiology, Department of Anaesthesiology, Pharmacology and Intensive Care, Geneva University Hospitals, Geneva, Switzerland
    Anaesthesia 61:826-31. 2006
    ..04. The hypnotic efficacy of propofol is reduced when used at low effect-site concentrations in smokers. This phenomenon may have some impact on the management of smokers undergoing sedation using target controlled infusion systems...
  8. ncbi request reprint Effects of fentanyl, alfentanil, remifentanil and sufentanil on loss of consciousness and bispectral index during propofol induction of anaesthesia
    C Lysakowski
    Division of Anaesthesiology, Geneva University Hospitals, Switzerland
    Br J Anaesth 86:523-7. 2001
    ..Although clinically the hypnotic effect of propofol is enhanced by analgesic concentrations of mu-agonist opioids, the BIS does not show this increased hypnotic effect...
  9. doi request reprint Intravenous lidocaine has no impact on rocuronium-induced neuromuscular block. Randomised study
    C Czarnetzki
    Division of Anaesthesiology, Geneva University Hospitals, Geneva, Switzerland
    Acta Anaesthesiol Scand 56:474-81. 2012
    ..Intravenous lidocaine is increasingly used in surgical patients. As it has neuromuscular blocking effects, we tested the impact of an intravenous lidocaine infusion on the time course of a rocuronium-induced neuromuscular block...
  10. doi request reprint Time course of rocuronium-induced neuromuscular block after pre-treatment with magnesium sulphate: a randomised study
    C Czarnetzki
    Division of Anaesthesiology, University Hospitals of Geneva, CH 1211 Geneva 14, Switzerland
    Acta Anaesthesiol Scand 54:299-306. 2010
    ..A previously published study suggested that pre-treatment with magnesium sulphate (MgSO(4)) had no impact on the speed of onset of rocuronium-induced neuromuscular block. We set out to verify this assumption...
  11. doi request reprint Benefit and risk of intrathecal morphine without local anaesthetic in patients undergoing major surgery: meta-analysis of randomized trials
    N Meylan
    Division of Anaesthesiology, University Hospitals of Geneva, 24, Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
    Br J Anaesth 102:156-67. 2009
    ..Morphine-sparing is more pronounced after abdominal than after cardiac-thoracic surgery. Respiratory depression remains a major safety concern...
  12. ncbi request reprint Does multimodal analgesia with acetaminophen, nonsteroidal antiinflammatory drugs, or selective cyclooxygenase-2 inhibitors and patient-controlled analgesia morphine offer advantages over morphine alone? Meta-analyses of randomized trials
    Nadia Elia
    Division of Anesthesiology, Geneva University Hospitals, 24 Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
    Anesthesiology 103:1296-304. 2005
    ..There is evidence that the combination of nonsteroidal antiinflammatory drugs with patient-controlled analgesia morphine offers some advantages over morphine alone...
  13. ncbi request reprint Plasma concentrations of brain-derived neurotrophic factor in patients undergoing minor surgery: a randomized controlled trial
    Laszlo Vutskits
    Division of Anesthesiology, University Hospitals of Geneva, 24, Rue Micheli du Crest, CH 1211, Geneva 14, Switzerland
    Neurochem Res 33:1325-31. 2008
    ..These data suggest that in males undergoing elective minor surgery, BDNF plasma concentrations show a specific pattern that is influenced by the anesthetic technique and, possibly, by the duration of surgery...
  14. ncbi request reprint A needle-free jet-injection system with lidocaine for peripheral intravenous cannula insertion: a randomized controlled trial with cost-effectiveness analysis
    Christopher Lysakowski
    Division of Anesthesiology, Department of APSIC Anesthesiology, Pharmacology, and Surgical Intensive Care, Geneva University Hospitals, Switzerland
    Anesth Analg 96:215-9, table of contents. 2003
    ..Lidocaine-Jet is analgesic; there is dose-responsiveness. However, Jet treatment is not painless, and costs incurred to achieve one success compared with doing nothing are not negligible...
  15. doi request reprint Nefopam for the prevention of postoperative pain: quantitative systematic review
    M S Evans
    Division of Anaesthesiology, University Hospitals of Geneva, Geneva, Switzerland
    Br J Anaesth 101:610-7. 2008
    ..However, dose responsiveness and adverse effect profile remain unclear, and the role of nefopam as part of multimodal analgesia needs to be established. Data in children are lacking...
  16. ncbi request reprint Propofol 1% versus propofol 2% in children undergoing minor ENT surgery
    M Pellegrini
    Division of Anaesthesiology, Department of Anaesthesiology, Geneva University Hospitals, Geneva, Switzerland
    Br J Anaesth 90:375-7. 2003
    ..The induction characteristics of propofol 1% and 2% were compared in children undergoing ENT surgery, in a prospective, randomized, double-blind study...
  17. doi request reprint Ventilation strategies in obese patients undergoing surgery: a quantitative systematic review and meta-analysis
    M Aldenkortt
    Division of Anaesthesia, Geneva University Hospitals, Rue Gabrielle Perret Gentil 4, 1211 Geneva 14, Switzerland
    Br J Anaesth 109:493-502. 2012
    ..The ideal ventilation strategy is expected to optimize gas exchange and pulmonary mechanics and to reduce the risk of respiratory complications...
  18. ncbi request reprint Dexamethasone and risk of nausea and vomiting and postoperative bleeding after tonsillectomy in children: a randomized trial
    Christoph Czarnetzki
    Division of Anesthesiology, University Hospitals of Geneva, 24 Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
    JAMA 300:2621-30. 2008
    ..Dexamethasone is widely used to prevent postoperative nausea and vomiting (PONV) in pediatric tonsillectomy...
  19. ncbi request reprint Prevention of succinylcholine-induced fasciculation and myalgia: a meta-analysis of randomized trials
    Jan Uwe Schreiber
    Department of Anesthesiology and Critical Care Medicine, University Hospital of the Saarland, Homburg, Germany
    Anesthesiology 103:877-84. 2005
    ..The risk of potentially serious adverse events with muscle relaxants is not negligible. Data that allow for a risk-benefit assessment are lacking for other drugs...
  20. ncbi request reprint Efficacy of low-dose acetazolamide for the prophylaxis of acute mountain sickness
    Lionel Dumont
    High Alt Med Biol 4:399; author reply 400. 2003