Angelika Lehner

Summary

Affiliation: University of Zurich
Country: Switzerland

Publications

  1. ncbi Development and application of oligonucleotide probes for in situ detection of thermotolerant Campylobacter in chicken faecal and liver samples
    Michael W Schmid
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut für Bodenökologie, Abteilung Rhizosphärenbiologie, Ingolstadter Landstr 1, D 85764 Neuherberg, Germany
    Int J Food Microbiol 105:245-55. 2005
  2. pmc The taxonomy of Enterobacter sakazakii: proposal of a new genus Cronobacter gen. nov. and descriptions of Cronobacter sakazakii comb. nov. Cronobacter sakazakii subsp. sakazakii, comb. nov., Cronobacter sakazakii subsp. malonaticus subsp. nov., Cronobacte
    Carol Iversen
    Quality and Safety Department, Nestle Research Centre, Vers chez les Blanc, Lausanne, Switzerland
    BMC Evol Biol 7:64. 2007
  3. pmc 16S rRNA gene based analysis of Enterobacter sakazakii strains from different sources and development of a PCR assay for identification
    Angelika Lehner
    Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, CH 8057 Zurich, Switzerland
    BMC Microbiol 4:43. 2004
  4. pmc Comparison of two chromogenic media and evaluation of two molecular based identification systems for Enterobacter sakazakii detection
    Angelika Lehner
    Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, CH 8057 Zurich, Switzerland
    BMC Microbiol 6:15. 2006
  5. doi Enterobacter pulveris sp. nov., isolated from fruit powder, infant formula and an infant formula production environment
    Roger Stephan
    Institute for Food Safety and Hygiene, Vetsuisse Faculty University of Zurich, Winterthurerstrasse 272, 8057 Zurich, Switzerland
    Int J Syst Evol Microbiol 58:237-41. 2008
  6. ncbi Cellulose as an extracellular matrix component present in Enterobacter sakazakii biofilms
    Maya Grimm
    Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, CH 8057 Zurich, Switzerland
    J Food Prot 71:13-8. 2008
  7. doi Cronobacter gen. nov., a new genus to accommodate the biogroups of Enterobacter sakazakii, and proposal of Cronobacter sakazakii gen. nov., comb. nov., Cronobacter malonaticus sp. nov., Cronobacter turicensis sp. nov., Cronobacter muytjensii sp. nov., Cro
    Carol Iversen
    Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, CH 8057, Zurich, Switzerland
    Int J Syst Evol Microbiol 58:1442-7. 2008
  8. pmc Genes involved in yellow pigmentation of Cronobacter sakazakii ES5 and influence of pigmentation on persistence and growth under environmental stress
    Sophia Johler
    Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, CH 8057 Zurich, Switzerland
    Appl Environ Microbiol 76:1053-61. 2010
  9. ncbi Molecular characterization of the alpha-glucosidase activity in Enterobacter sakazakii reveals the presence of a putative gene cluster for palatinose metabolism
    Angelika Lehner
    Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, Winterthurerstr 272, Zurich, Switzerland
    Syst Appl Microbiol 29:609-25. 2006
  10. doi Outbreak of Staphylococcal food poisoning due to SEA-producing Staphylococcus aureus
    Sophia Johler
    Institute for Food Safety and Hygiene, Vetsuisse Faculty University of Zurich, Zurich, Switzerland
    Foodborne Pathog Dis 10:777-81. 2013

Collaborators

Detail Information

Publications36

  1. ncbi Development and application of oligonucleotide probes for in situ detection of thermotolerant Campylobacter in chicken faecal and liver samples
    Michael W Schmid
    GSF Forschungszentrum für Umwelt und Gesundheit, Institut für Bodenökologie, Abteilung Rhizosphärenbiologie, Ingolstadter Landstr 1, D 85764 Neuherberg, Germany
    Int J Food Microbiol 105:245-55. 2005
    ..Campylobacter spp. detection by FISH using highly specific probes looks promising to become a future monitoring system in a logistic poultry slaughter concept...
  2. pmc The taxonomy of Enterobacter sakazakii: proposal of a new genus Cronobacter gen. nov. and descriptions of Cronobacter sakazakii comb. nov. Cronobacter sakazakii subsp. sakazakii, comb. nov., Cronobacter sakazakii subsp. malonaticus subsp. nov., Cronobacte
    Carol Iversen
    Quality and Safety Department, Nestle Research Centre, Vers chez les Blanc, Lausanne, Switzerland
    BMC Evol Biol 7:64. 2007
    ..When the species was defined in 1980, 15 biogroups were described and it was suggested that these could represent multiple species. In this study the taxonomic relationship of strains described as E. sakazakii was further investigated...
  3. pmc 16S rRNA gene based analysis of Enterobacter sakazakii strains from different sources and development of a PCR assay for identification
    Angelika Lehner
    Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, CH 8057 Zurich, Switzerland
    BMC Microbiol 4:43. 2004
    ..sakazakii strains from food, environment and human origin as well as the type strain ATCC 51329 were sequenced. Based on this sequence data a new specific PCR system for E. sakazakii was developed and evaluated...
  4. pmc Comparison of two chromogenic media and evaluation of two molecular based identification systems for Enterobacter sakazakii detection
    Angelika Lehner
    Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, CH 8057 Zurich, Switzerland
    BMC Microbiol 6:15. 2006
    ..sakazakii were evaluated on 98 target and non-target strains. The methods were compared with respect to specificity aspects...
  5. doi Enterobacter pulveris sp. nov., isolated from fruit powder, infant formula and an infant formula production environment
    Roger Stephan
    Institute for Food Safety and Hygiene, Vetsuisse Faculty University of Zurich, Winterthurerstrasse 272, 8057 Zurich, Switzerland
    Int J Syst Evol Microbiol 58:237-41. 2008
    ..nov. The type strain is 601/05(T) (=LMG 24057(T)=DSM 19144(T))...
  6. ncbi Cellulose as an extracellular matrix component present in Enterobacter sakazakii biofilms
    Maya Grimm
    Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, CH 8057 Zurich, Switzerland
    J Food Prot 71:13-8. 2008
    ..For the first time, the presence of cellulose in biofilms produced by E. sakazakii was confirmed by methylation analysis...
  7. doi Cronobacter gen. nov., a new genus to accommodate the biogroups of Enterobacter sakazakii, and proposal of Cronobacter sakazakii gen. nov., comb. nov., Cronobacter malonaticus sp. nov., Cronobacter turicensis sp. nov., Cronobacter muytjensii sp. nov., Cro
    Carol Iversen
    Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, CH 8057, Zurich, Switzerland
    Int J Syst Evol Microbiol 58:1442-7. 2008
    ..lausannensis subsp. nov. [type strain E515(T) (=LMG 23824=DSM 18706(T))], and Cronobacter dublinensis subsp. lactaridi subsp. nov. [type strain E464(T) (=LMG 23825(T)=DSM 18707(T))]...
  8. pmc Genes involved in yellow pigmentation of Cronobacter sakazakii ES5 and influence of pigmentation on persistence and growth under environmental stress
    Sophia Johler
    Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, CH 8057 Zurich, Switzerland
    Appl Environ Microbiol 76:1053-61. 2010
    ..Moreover, DeltacrtE and DeltacrtY exhibited increased sensitivity to UVB irradiation...
  9. ncbi Molecular characterization of the alpha-glucosidase activity in Enterobacter sakazakii reveals the presence of a putative gene cluster for palatinose metabolism
    Angelika Lehner
    Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, Winterthurerstr 272, Zurich, Switzerland
    Syst Appl Microbiol 29:609-25. 2006
    ..The presence of the postulated palatinose metabolism was proven by growth experiments using this sugar as a sole carbon source...
  10. doi Outbreak of Staphylococcal food poisoning due to SEA-producing Staphylococcus aureus
    Sophia Johler
    Institute for Food Safety and Hygiene, Vetsuisse Faculty University of Zurich, Zurich, Switzerland
    Foodborne Pathog Dis 10:777-81. 2013
    ..This is one of only a few studies that were able to link a staphylococcal food poisoning outbreak to its source...
  11. pmc Development of a novel screening method for the isolation of "Cronobacter" spp. (Enterobacter sakazakii)
    Carol Iversen
    Institute for Food Safety and Hygiene, Vetsuisse Faculty University of Zurich, Winterthurerstrasse 272, 8057 Zurich, Switzerland
    Appl Environ Microbiol 74:2550-3. 2008
    ....
  12. pmc Genes involved in Cronobacter sakazakii biofilm formation
    Isabel Hartmann
    Institute for Food Safety and Hygiene, Winterthurerestrasse 272, 8057 Zurich, Switzerland
    Appl Environ Microbiol 76:2251-61. 2010
    ..Our findings suggest that flagella and hypothetical proteins ESA_00281 and ESA_00282, but not cellulose, contribute to adhesion of Cronobacter to this biotic surface...
  13. pmc Rapid genus- and species-specific identification of Cronobacter spp. by matrix-assisted laser desorption ionization-time of flight mass spectrometry
    Roger Stephan
    Institute for Food Safety and Hygiene, Vetsuisse Faculty University of Zurich, Winterthurerstr 272, CH 8057 Zurich, Switzerland
    J Clin Microbiol 48:2846-51. 2010
    ..Our study demonstrates that MALDI-TOF MS is a reliable and powerful tool for the rapid identification of Cronobacter strains to the genus and species level...
  14. ncbi Cloning and characterization of Enterobacter sakazakii pigment genes and in situ spectroscopic analysis of the pigment
    Angelika Lehner
    Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
    FEMS Microbiol Lett 265:244-8. 2006
    ..The carotenogenic nature of the pigment of Enterobacter sakazakii wt was ascertained by in situ analysis using visible microspectroscopy and resonance Raman microspectroscopy...
  15. pmc Identification of genes involved in serum tolerance in the clinical strain Cronobacter sakazakii ES5
    Sarah Schwizer
    Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
    BMC Microbiol 13:38. 2013
    ..It was the aim of the current study to identify genes involved in serum tolerance in a selected Cronobacter sakazakii strain of clinical origin...
  16. doi Genetic diversity of Cronobacter sakazakii isolates collected from a Swiss infant formula production facility
    Andrea Müller
    Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
    J Food Prot 76:883-7. 2013
    ..Generally, the observed heterogeneity among strains collected over the 13 months of the monitoring program was high, suggesting a constant flux among strains rather than a selection for persisting organisms...
  17. pmc Adhesive properties of Enterobacter sakazakii to human epithelial and brain microvascular endothelial cells
    Jean Philippe Mange
    Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, CH 8057 Zurich, Switzerland
    BMC Microbiol 6:58. 2006
    ..Furthermore, the effects of bacterial culture conditions on the adherence behaviour were investigated. An attempt was made to characterize the factors involved in adherence...
  18. ncbi Biofilm formation, extracellular polysaccharide production, and cell-to-cell signaling in various Enterobacter sakazakii strains: aspects promoting environmental persistence
    Angelika Lehner
    Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, CH 8057 Zurich, Switzerland
    J Food Prot 68:2287-94. 2005
    ..These findings illustrate the ability of E. sakazakii to produce cell-to-cell signaling molecules...
  19. pmc The DSF type quorum sensing signalling system RpfF/R regulates diverse phenotypes in the opportunistic pathogen Cronobacter
    Angela Suppiger
    Department of Microbiology, University of Zurich, Ch 8008 Zurich, Switzerland
    Sci Rep 6:18753. 2016
    ..This first report on an RpfF/R-type QS system of an organism outside the genus Burkholderia revealed that both the underlying molecular mechanisms as well as the regulated functions show a high degree of conservation. ..
  20. doi Distribution and identification of culturable airborne microorganisms in a Swiss milk processing facility
    Helmut Brandl
    University of Zurich, Institute of Evolutionary Biology and Environmental Studies, CH 8057 Zurich, Switzerland Electronic address
    J Dairy Sci 97:240-6. 2014
    ..The data generated in this study could be used to evaluate the effectiveness of the dairy plant's sanitation program and to identify potential sources of airborne contamination, resulting in increased food safety...
  21. pmc Identification of "Cronobacter" spp. (Enterobacter sakazakii)
    Carol Iversen
    Institute for Food Safety and Hygiene, University of Zurich, Winterthurerstrasse 272, CH 8057, Zurich, Switzerland
    J Clin Microbiol 45:3814-6. 2007
    ..All "Cronobacter" isolates were positive using dnaG and gluA PCR protocols, and all expressed alpha-glucosidase activity. ID32E v3.0 identified 99.5% of "Cronobacter" isolates (as the nearest match to E. sakazakii)...
  22. pmc Complete genome sequence of Cronobacter turicensis LMG 23827, a food-borne pathogen causing deaths in neonates
    Roger Stephan
    Institute for Food Safety and Hygiene, Vetsuisse Faculty University of Zurich, Winterthurerstrasse 272, 8057 Zurich, Switzerland
    J Bacteriol 193:309-10. 2011
    ..Among all proteins of C. turicensis, 223 have been annotated as virulence- and disease-related proteins...
  23. ncbi Identification of proteins involved in osmotic stress response in Enterobacter sakazakii by proteomics
    Kathrin Riedel
    Department of Microbiology, Institute of Plant Biology, University of Zurich, Zurich, Switzerland
    Proteomics 7:1217-31. 2007
    ..The most striking effects observed for both types of osmotic stress in E. sakazakii were a significant down-regulation of the motility apparatus and the formation of filamentous cells...
  24. pmc Linking Genomo- and Pathotype: Exploiting the Zebrafish Embryo Model to Investigate the Divergent Virulence Potential among Cronobacter spp
    Athmanya K Eshwar
    Institute for Food Safety and Hygiene, University of Zurich, Zurich, Switzerland
    PLoS ONE 11:e0158428. 2016
    ..We propose that by using this model in vivo infection studies are now possible on a large scale level which will boost the understanding on the virulence strategies employed by these pathogens. ..
  25. doi Influence of FkpA variants on survival and replication of Cronobacter spp. in human macrophages
    Athmanya Konegadde Eshwar
    Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, Winterthurerstr 272, CH 8057 Zurich, Switzerland Electronic address
    Res Microbiol 166:186-95. 2015
    ..FkpA must be considered a virulence factor, but its influence on macrophage survival and replication varies among strains and/or species due to the presence of amino acid variations...
  26. doi Characterization of Listeria monocytogenes strains isolated during 2011-2013 from human infections in Switzerland
    Denise Althaus
    1 Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
    Foodborne Pathog Dis 11:753-8. 2014
    ..Screening for Listeriolysin S showed the presence of this virulence factor in 29 of the 33 genetic lineage I strains. By using ApaI and AscI for pulsed-field gel electrophoresis, most strains showed distinguishable patterns...
  27. doi Presence of AmpC beta-lactamases, CSA-1, CSA-2, CMA-1, and CMA-2 conferring an unusual resistance phenotype in Cronobacter sakazakii and Cronobacter malonaticus
    Andrea Müller
    Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
    Microb Drug Resist 20:275-80. 2014
    ..coli host. ..
  28. ncbi Enterobacter turicensis sp. nov. and Enterobacter helveticus sp. nov., isolated from fruit powder
    Roger Stephan
    Institute for Food Safety and Hygiene, Vetsuisse Faculty University of Zurich, Winterthurerstrasse 272, 8057 Zurich, Switzerland
    Int J Syst Evol Microbiol 57:820-6. 2007
    ..nov. (type strain 508/05(T)=LMG 23730(T)=DSM 18397(T)) and Enterobacter helveticus sp. nov. (type strain 513/05(T)=LMG 23732(T)=DSM 18396(T))...
  29. ncbi The microbial community composition of a nitrifying-denitrifying activated sludge from an industrial sewage treatment plant analyzed by the full-cycle rRNA approach
    Stefan Juretschko
    Lehrstuhl fur Mikrobiologie, Technische Universitat Munchen, Freising, Germany
    Syst Appl Microbiol 25:84-99. 2002
    ..Taken together, this study provides the first encompassing, high-resolution insight into the in situ composition of the microbial community present in a full-scale, industrial wastewater treatment plant...
  30. pmc 16S rRNA gene-based oligonucleotide microarray for environmental monitoring of the betaproteobacterial order "Rhodocyclales"
    Alexander Loy
    Department of Microbial Ecology, Institute of Ecology and Conservation Biology, University of Vienna, Vienna, Austria
    Appl Environ Microbiol 71:1373-86. 2005
    ....
  31. pmc Oligonucleotide microarray for 16S rRNA gene-based detection of all recognized lineages of sulfate-reducing prokaryotes in the environment
    Alexander Loy
    Lehrstuhl fur Mikrobiologie, Technische Universitat Munchen, D 85350 Freising, Germany
    Appl Environ Microbiol 68:5064-81. 2002
    ....
  32. pmc The isotope array, a new tool that employs substrate-mediated labeling of rRNA for determination of microbial community structure and function
    Justyna Adamczyk
    Lehrstuhl fur Mikrobiologie, Technische Universitat Munchen, D 85350 Freising, Germany
    Appl Environ Microbiol 69:6875-87. 2003
    ....
  33. pmc Microarray and functional gene analyses of sulfate-reducing prokaryotes in low-sulfate, acidic fens reveal cooccurrence of recognized genera and novel lineages
    Alexander Loy
    Department of Microbial Ecology, Institute of Ecology and Conservation Biology, University of Vienna, Vienna, Austria
    Appl Environ Microbiol 70:6998-7009. 2004
    ..These dsrAB sequences had no features indicative of pseudogenes and likely represent novel, deeply branching, sulfate- or sulfite-reducing prokaryotes that are specialized colonists of low-sulfate habitats...
  34. ncbi Oligonucleotide microarray for identification of Enterococcus species
    Angelika Lehner
    Department of Microbiology, Technical University of Munich, D 85350 Freising, Germany
    FEMS Microbiol Lett 246:133-42. 2005
    ....
  35. ncbi Deciphering the evolution and metabolism of an anammox bacterium from a community genome
    Marc Strous
    Department of Microbiology, IWWR, Radboud University Nijmegen, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands
    Nature 440:790-4. 2006
    ..Most significantly, we identified candidate genes responsible for ladderane biosynthesis and biological hydrazine metabolism, and discovered unexpected metabolic versatility...
  36. doi Endophytic root colonization of gramineous plants by Herbaspirillum frisingense
    Michael Rothballer
    Department Microbe Plant Interactions, Helmholtz Center Munich, German Research Center for Environmental Health GmbH, Munich, Germany
    FEMS Microbiol Ecol 66:85-95. 2008
    ..frisingense as a true plant endophyte and, although initial greenhouse experiments did not lead to clear plant growth stimulation, demonstrate the potential of this species for beneficial effects on the growth of crop plants...