J E Kaufmann
Affiliation: University of Geneva
- Vasopressin-induced von Willebrand factor secretion from endothelial cells involves V2 receptors and cAMPJ E Kaufmann
Division of Clinical Biochemistry, Geneva, Switzerland Research Institute for Molecular Pharmacology, Berlin, Germany
J Clin Invest 106:107-16. 2000..They also demonstrate functional expression of V2R in endothelial cells, and provide a cellular mechanism for the hemostatic effects of DDAVP...
- Desmopressin (DDAVP) induces NO production in human endothelial cells via V2 receptor- and cAMP-mediated signalingJ E Kaufmann
Division of Clinical Biochemistry, and Department of Geriatric Medicine, Geneva, Switzerland
J Thromb Haemost 1:821-8. 2003..These results indicate that DDAVP and other cAMP-raising agents can activate eNOS via PI3K-independent Ser1177 phosphorylation in human endothelial cells. This mechanism most likely accounts for DDAVP-induced vasodilation...
- Cellular mechanisms of the hemostatic effects of desmopressin (DDAVP)J E Kaufmann
Division of Clinical Biochemistry, Geneva, Switzerland
J Thromb Haemost 1:682-9. 2003..The mechanism of action of DDAVP on FVIII plasma levels remains to be elucidated. The hemostatic effect of DDAVP likely involves additional cellular effects that remain to be discovered...
- The regulation of endothelial VWF secretion by nitric oxide: is it physiological?S Zarei
J Thromb Haemost 4:263-5. 2006