Affiliation: University Hospital
- Functional imaging in mild cognitive impairment and early Alzheimer's disease: is it pertinent?Vicente Ibanez
Neuroimaging Unit, Department of Psychiatry, University Hospitals of Geneva, Chene Bourg, Geneva, Switzerland
Front Neurol Neurosci 24:30-8. 2009..Finally, the use of biomarkers of the neuropathological lesions constitutes the most promising tool to accurately diagnose MCI and early AD patients...
- Early event-related potential changes during working memory activation predict rapid decline in mild cognitive impairmentPascal Missonnier
Neuroimaging Unit, Department of Psychiatry, University of Hospitals Geneva, Ch Pont Bochet 3, 1226 Thonex Geneva, Switzerland
J Gerontol A Biol Sci Med Sci 60:660-6. 2005..Using a "2-back" activation paradigm, we recently described an electrophysiological correlate of working memory activation (positive-negative working memory [PN(wm)] component) over parietal electrodes...
- Evaluation of the reference tissue models for PET and SPECT benzodiazepine binding parametersPhilippe Millet
Division de Neuropsychiatrie, Unité de Neuroimagerie Psychiatrique, Hopitaux Universitaires de Geneve, Geneva, Switzerland
Neuroimage 17:928-42. 2002..It seems that the physiological values found in gray matter structures using these radioligands give acceptable BP values. We conclude that the reference tissue methods should be carefully evaluated for each radioligand...
- In vivo quantification of 5-HT1A-[18F]MPPF interactions in rats using the YAP-(S)PET scanner and a beta-microprobePhilippe Millet
Psychiatric Neuroimaging Unit, Division of Neuropsychiatry, Department of Psychiatry, University Hospital of Geneva, Switzerland
Neuroimage 41:823-34. 2008..895) and YAP-(S)PET (r=0.695). The YAP-(S)PET system underestimated the [18F]MPPF binding levels in brain due to limited resolution (i.e. partial volume), but led to similar conclusions...
- Distinction between perceptual and attentional processing in working memory tasks: a study of phase-locked and induced oscillatory brain dynamicsMarie Pierre Deiber
University Hospitals of Geneva, Switzerland
J Cogn Neurosci 19:158-72. 2007..Induced theta and beta activities displayed respectively a frontal and parietal topographical distribution, providing further functional information on the fronto-posterior network supporting working memory...
- SPECT quantification of benzodiazepine receptor concentration using a dual-ligand approachPhilippe Millet
Psychiatric Neuroimaging Unit, Division of Neuropsychiatry, Department of Psychiatry, University Hospitals of Geneva, Geneva, Switzerland
J Nucl Med 47:783-92. 2006..In this study, we applied a dual-ligand protocol using the unlabeled ligand flumazenil, which lacks pharmacologic effects, to quantify all binding parameters of the benzodiazepine receptor-(123)I-iomazenil interactions...
- Chloramphenicol decreases brain glucose utilization and modifies the sleep-wake cycle architecture in ratsMarcelle Moulin-Sallanon
IFR19, Institut Federatif des Neurosciences de Lyon, Bron, France
J Neurochem 93:1623-32. 2005..Spectral analysis of the electroencephalogram indicates that chloramphenicol induces long-lasting modifications of delta-band power during slow-wave sleep...
- In vivo measurement of glucose utilization in rats using a beta-microprobe: direct comparison with autoradiographyPhilippe Millet
Unité de Neuroimagerie, Service de Neuropsychiatrie, Hopitaux Universitaires de Geneve, Chene Bourg, Switzerland
J Cereb Blood Flow Metab 24:1015-24. 2004..In addition, the betaP-derived input function was similar to that obtained by manual sampling. Our findings show that reliable rCMRglc values can be obtained using betaP...
- Age-associated modulations of cerebral oscillatory patterns related to attention controlMarie Pierre Deiber
INSERM U1039, Faculty of Medicine, Domaine de la Merci, 38700 La Tronche, France
Neuroimage 82:531-46. 2013....
- Spectral analysis of the sleep onset period in primary insomniaKaterina Cervena
Sleep Laboratory, Department of Psychiatry, University Hospitals of Geneva, Geneva, Switzerland Electronic address
Clin Neurophysiol 125:979-87. 2014..To compare the EEG power spectra characteristics of the sleep onset period (SOP) in patients with sleep onset insomnia (SOI), sleep maintenance insomnia (SMI) and good sleepers (GS)...
- Cortical distinction between the neural encoding of objects that appear to glow and those that do notUte Leonards
Neuroimaging Unit, Department of Psychiatry, University Hospitals of Geneva, CH 1225 Chêne Bourg Geneva, Switzerland
Brain Res Cogn Brain Res 24:173-6. 2005..Possible functional reasons for the existence of such an area are discussed...
- Influence of sleep stage and wakefulness on spectral EEG activity and heart rate variations around periodic leg movementsSuzie Lavoie
Sleep Laboratory, Department of Psychiatry, University Hospital of Geneva, Geneva, Switzerland
Clin Neurophysiol 115:2236-46. 2004..We aimed to determine the effects of sleep stage and wakefulness on these responses to ascertain whether a common pattern of EEG and HR activation takes place...
- Abnormal-induced theta activity supports early directed-attention network deficits in progressive MCIMarie Pierre Deiber
Department of Psychiatry, University Hospitals of Geneva, Switzerland
Neurobiol Aging 30:1444-52. 2009..While performance is maintained, the decrease of induced theta activity suggests early deficits in the directed-attention network in progressive MCI, whereas this network is functionally preserved in stable MCI...
- An alternative measure of sleep fragmentation in clinical practice: the sleep fragmentation indexJosé Haba-Rubio
Sleep Laboratory, Department of Psychiatry, University Hospital, Geneva, Switzerland
Sleep Med 5:577-81. 2004..The aim of our study was to investigate the usefulness of a sleep fragmentation index (SFI) to detect sleep disruption in a large sample of patients...