Clemens D Cohen

Summary

Affiliation: University of Zurich
Country: Switzerland

Publications

  1. pmc Transcript-specific expression profiles derived from sequence-based analysis of standard microarrays
    Anton G Moll
    Institute of Physiology and Clinic for Nephrology, University of Zurich, Zurich, Switzerland
    PLoS ONE 4:e4702. 2009
  2. pmc Systematic analysis of a novel human renal glomerulus-enriched gene expression dataset
    Maja T Lindenmeyer
    Division of Nephrology, University Hospital Zurich, Zurich, Switzerland
    PLoS ONE 5:e11545. 2010
  3. pmc Bone morphogenetic protein (BMP)-7 expression is decreased in human hypertensive nephrosclerosis
    Carsten P Bramlage
    Department of Medicine, Nephrology and Rheumatology, Georg August University Gottingen, Robert Koch Strasse 40, 37075 Gottingen, Germany
    BMC Nephrol 11:31. 2010
  4. pmc Human nephrosclerosis triggers a hypoxia-related glomerulopathy
    Matthias A Neusser
    Clinic and Policlinic for Internal Medicine, University Hospital Zurich, 8057 Zurich, Switzerland
    Am J Pathol 176:594-607. 2010
  5. doi request reprint Intrarenal production of B-cell survival factors in human lupus nephritis
    Matthias A Neusser
    Division of Nephrology, Department of Internal Medicine, University Hospital, Zurich, Switzerland
    Mod Pathol 24:98-107. 2011
  6. ncbi request reprint Renal tubular PD-L1 (CD274) suppresses alloreactive human T-cell responses
    Astrid Starke
    Institute of Physiology, Zurich Center for Integrative Human Physiology, University of Zurich, and Department of Urology, University Hospital Zurich, Zurich, Switzerland
    Kidney Int 78:38-47. 2010
  7. pmc Improved elucidation of biological processes linked to diabetic nephropathy by single probe-based microarray data analysis
    Clemens D Cohen
    Nephrology Clinic and Institute of Physiology with Center of Integrative Human Physiology, University Hospital and University, Zurich, Switzerland
    PLoS ONE 3:e2937. 2008
  8. doi request reprint Expression of the chemokine receptor CCR6 in human renal inflammation
    Desa Welsh-Bacic
    Division of Nephrology, University Hospital, Zurich, Switzerland
    Nephrol Dial Transplant 26:1211-20. 2011
  9. doi request reprint The chemokine receptor CXCR7 is expressed on lymphatic endothelial cells during renal allograft rejection
    Matthias A Neusser
    Division of Nephrology, University Hospital, Zurich 8091, Switzerland
    Kidney Int 77:801-8. 2010
  10. pmc Anti-hLAMP2-antibodies and dual positivity for anti-GBM and MPO-ANCA in a patient with relapsing pulmonary-renal syndrome
    Christoph Etter
    Division of Nephrology, University Hospital Zurich, Zurich, Switzerland
    BMC Nephrol 12:26. 2011

Collaborators

Detail Information

Publications12

  1. pmc Transcript-specific expression profiles derived from sequence-based analysis of standard microarrays
    Anton G Moll
    Institute of Physiology and Clinic for Nephrology, University of Zurich, Zurich, Switzerland
    PLoS ONE 4:e4702. 2009
    ..Nevertheless, the re-analysis of established microarray data using newly defined transcript-specific probe sets may provide information about expression levels of specific transcripts...
  2. pmc Systematic analysis of a novel human renal glomerulus-enriched gene expression dataset
    Maja T Lindenmeyer
    Division of Nephrology, University Hospital Zurich, Zurich, Switzerland
    PLoS ONE 5:e11545. 2010
    ..A systematic analysis of this glomerulus-specific gene expression dataset allows the detection of target molecules and biological processes involved in glomerular biology and renal disease...
  3. pmc Bone morphogenetic protein (BMP)-7 expression is decreased in human hypertensive nephrosclerosis
    Carsten P Bramlage
    Department of Medicine, Nephrology and Rheumatology, Georg August University Gottingen, Robert Koch Strasse 40, 37075 Gottingen, Germany
    BMC Nephrol 11:31. 2010
    ..Bone Morphogenetic Protein (BMP)-7 is protective in different animal models of acute and chronic kidney disease. Its role in human kidneys, and in particular hypertensive nephrosclerosis, has thus far not been described...
  4. pmc Human nephrosclerosis triggers a hypoxia-related glomerulopathy
    Matthias A Neusser
    Clinic and Policlinic for Internal Medicine, University Hospital Zurich, 8057 Zurich, Switzerland
    Am J Pathol 176:594-607. 2010
    ..These data support a role for CXCR4/CXCL12 in human NSC and indicate that hypoxia not only is involved in tubulointerstitial fibrosis but also contributes to glomerular damage in NSC...
  5. doi request reprint Intrarenal production of B-cell survival factors in human lupus nephritis
    Matthias A Neusser
    Division of Nephrology, Department of Internal Medicine, University Hospital, Zurich, Switzerland
    Mod Pathol 24:98-107. 2011
    ..This information might help define intrarenal effects of APRIL and BLyS inhibition in human lupus nephritis...
  6. ncbi request reprint Renal tubular PD-L1 (CD274) suppresses alloreactive human T-cell responses
    Astrid Starke
    Institute of Physiology, Zurich Center for Integrative Human Physiology, University of Zurich, and Department of Urology, University Hospital Zurich, Zurich, Switzerland
    Kidney Int 78:38-47. 2010
    ..The upregulation of PD-L1 on proximal tubular epithelial cells in patients with acute allograft rejection may reduce T-cell-mediated injury...
  7. pmc Improved elucidation of biological processes linked to diabetic nephropathy by single probe-based microarray data analysis
    Clemens D Cohen
    Nephrology Clinic and Institute of Physiology with Center of Integrative Human Physiology, University Hospital and University, Zurich, Switzerland
    PLoS ONE 3:e2937. 2008
    ..Effective transcriptomic profiling of slowly evolving disease processes such as DN can be problematic. The changes that occur are often subtle and can escape detection by conventional oligonucleotide DNA array analyses...
  8. doi request reprint Expression of the chemokine receptor CCR6 in human renal inflammation
    Desa Welsh-Bacic
    Division of Nephrology, University Hospital, Zurich, Switzerland
    Nephrol Dial Transplant 26:1211-20. 2011
    ..CCR6 and the corresponding ligand CCL20 are involved in the formation of gut-associated lymphatic tissue. We hypothesized that CCR6 might be involved in the formation of nodular infiltrates in the kidney...
  9. doi request reprint The chemokine receptor CXCR7 is expressed on lymphatic endothelial cells during renal allograft rejection
    Matthias A Neusser
    Division of Nephrology, University Hospital, Zurich 8091, Switzerland
    Kidney Int 77:801-8. 2010
    ..Whether its presence modulates the formation of chemokine gradients and the recruitment of inflammatory cells will require further experimental studies...
  10. pmc Anti-hLAMP2-antibodies and dual positivity for anti-GBM and MPO-ANCA in a patient with relapsing pulmonary-renal syndrome
    Christoph Etter
    Division of Nephrology, University Hospital Zurich, Zurich, Switzerland
    BMC Nephrol 12:26. 2011
    ..Whilst anti-GBM disease is considered a non-relapsing condition, the long-term course of double-positive patients is less predictable...
  11. doi request reprint Predicting an allograft's fate
    Thomas Fehr
    Division of Nephrology, University Hospital Zurich, Zurich, Switzerland
    Kidney Int 80:1254-5. 2011
    ..Identifying such 'sub-morphological' markers should help us to better understand biological processes leading to chronic allograft failure...
  12. pmc Kidney diseases caused by complement dysregulation: acquired, inherited, and still more to come
    Saskia F Heeringa
    Division of Internal Medicine, University Hospital Zurich, Switzerland
    Clin Dev Immunol 2012:695131. 2012
    ..However, further elucidation of the underlying defects in the alternative complement pathway is awaited to develop pathogenesis-specific therapies...