Emanuel R Christ

Summary

Affiliation: University Hospital
Country: Switzerland

Publications

  1. ncbi request reprint Effect of IGF-I therapy on VLDL apolipoprotein B100 metabolism in type 1 diabetes mellitus
    Emanuel R Christ
    Department of Endocrinology and Diabetology of the Adult, University Hospital of Bern, Inselspital, CH 3010 Bern, Switzerland
    Am J Physiol Endocrinol Metab 282:E1154-62. 2002
  2. ncbi request reprint Normal VLDL metabolism despite altered lipoprotein composition in type 1 diabetes mellitus
    E R Christ
    Department of Medicine, King s College London, St Thomas s Hospital, UK
    Clin Endocrinol (Oxf) 55:777-87. 2001
  3. ncbi request reprint The effect of growth hormone (GH) replacement therapy in adult patients with type 1 diabetes mellitus and GH deficiency
    E R Christ
    Department of Medicine, King s College London, St Thomas Hospital Campus, London SE1 7EH, UK
    Clin Endocrinol (Oxf) 58:309-15. 2003
  4. ncbi request reprint The effect of increased lipid intake on hormonal responses during aerobic exercise in endurance-trained men
    Emanuel R Christ
    Division of Endocrinology and Diabetes, University Hospital of Berne, Switzerland
    Eur J Endocrinol 154:397-403. 2006
  5. ncbi request reprint Intramyocellular lipid stores increase markedly in athletes after 1.5 days lipid supplementation and are utilized during exercise in proportion to their content
    Monica Zehnder
    Department of Clinical Research, University and Inselspital, 3010, Bern, Switzerland
    Eur J Appl Physiol 98:341-54. 2006
  6. ncbi request reprint Differential effect of pioglitazone (PGZ) and rosiglitazone (RGZ) on postprandial glucose and lipid metabolism in patients with type 2 diabetes mellitus: a prospective, randomized crossover study
    Bernard Chappuis
    Division of Endocrinology, Diabetes and Clinical Nutrition, University Hospital of Berne, Inselspital, CH 3010 Bern, Switzerland
    Diabetes Metab Res Rev 23:392-9. 2007
  7. ncbi request reprint Dehydroepiandrosterone sulfate in the assessment of the hypothalamic-pituitary-adrenal axis
    Stefan Fischli
    Division of Endocrinology, Diabetes, and Clinical Nutrition, Division of Clinical Epidemiology and Biostatistics, Inselspital, University of Bern, CH 3010 Bern, Switzerland
    J Clin Endocrinol Metab 93:539-42. 2008
  8. ncbi request reprint Low-density lipoprotein apolipoprotein B100 turnover in hypopituitary patients with GH deficiency: a stable isotope study
    Emanuel R Christ
    Department of Endocrinology and Diabetology, University Hospital of Bern, Switzerland
    Eur J Endocrinol 154:459-66. 2006
  9. doi request reprint Effect of GH on human skeletal muscle lipid metabolism in GH deficiency
    Roman Trepp
    Division of Endocrinology, Diabetology and Clinical Nutrition, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland
    Am J Physiol Endocrinol Metab 294:E1127-34. 2008
  10. ncbi request reprint Exercise capacity in subjects with type 1 diabetes mellitus in eu- and hyperglycaemia
    Christoph Stettler
    Division of Endocrinology and Diabetes, University of Bern Inselspital, 3010 Bern, Switzerland
    Diabetes Metab Res Rev 22:300-6. 2006

Collaborators

Detail Information

Publications32

  1. ncbi request reprint Effect of IGF-I therapy on VLDL apolipoprotein B100 metabolism in type 1 diabetes mellitus
    Emanuel R Christ
    Department of Endocrinology and Diabetology of the Adult, University Hospital of Bern, Inselspital, CH 3010 Bern, Switzerland
    Am J Physiol Endocrinol Metab 282:E1154-62. 2002
    ..These results indicate that low-dose IGF-I therapy restores the GH-IGF-I axis in type 1 diabetes. IGF-I therapy changes fasting triglyceride concentrations and VLDL composition probably because of an increase in insulin sensitivity...
  2. ncbi request reprint Normal VLDL metabolism despite altered lipoprotein composition in type 1 diabetes mellitus
    E R Christ
    Department of Medicine, King s College London, St Thomas s Hospital, UK
    Clin Endocrinol (Oxf) 55:777-87. 2001
    ..Secretion and clearance of VLDL apolipoprotein B100 (apoB) are important determinants of plasma lipid concentrations and are known to be influenced by hormones, including insulin and growth hormone...
  3. ncbi request reprint The effect of growth hormone (GH) replacement therapy in adult patients with type 1 diabetes mellitus and GH deficiency
    E R Christ
    Department of Medicine, King s College London, St Thomas Hospital Campus, London SE1 7EH, UK
    Clin Endocrinol (Oxf) 58:309-15. 2003
    ..Specific problems in patients with insulin-dependent diabetes mellitus (IDDM) and GH deficiency are hypoglycaemic attacks, increased insulin sensitivity and loss of energy. These problems may be related to GH deficiency...
  4. ncbi request reprint The effect of increased lipid intake on hormonal responses during aerobic exercise in endurance-trained men
    Emanuel R Christ
    Division of Endocrinology and Diabetes, University Hospital of Berne, Switzerland
    Eur J Endocrinol 154:397-403. 2006
    ..These data suggest that acute negative energy balance induced by exercise elicits a hormonal response with opposite changes of ghrelin and leptin. In addition, the hormonal response is modulated by the preceding intake of fat...
  5. ncbi request reprint Intramyocellular lipid stores increase markedly in athletes after 1.5 days lipid supplementation and are utilized during exercise in proportion to their content
    Monica Zehnder
    Department of Clinical Research, University and Inselspital, 3010, Bern, Switzerland
    Eur J Appl Physiol 98:341-54. 2006
    ..5 days. During subsequent exercise, IMCL decrease in proportion to their initial content, partly in exchange for peripheral fatty acids...
  6. ncbi request reprint Differential effect of pioglitazone (PGZ) and rosiglitazone (RGZ) on postprandial glucose and lipid metabolism in patients with type 2 diabetes mellitus: a prospective, randomized crossover study
    Bernard Chappuis
    Division of Endocrinology, Diabetes and Clinical Nutrition, University Hospital of Berne, Inselspital, CH 3010 Bern, Switzerland
    Diabetes Metab Res Rev 23:392-9. 2007
    ..This study investigated the effects of RGZ and PGZ on postprandial metabolism in a prospective, randomized crossover trial...
  7. ncbi request reprint Dehydroepiandrosterone sulfate in the assessment of the hypothalamic-pituitary-adrenal axis
    Stefan Fischli
    Division of Endocrinology, Diabetes, and Clinical Nutrition, Division of Clinical Epidemiology and Biostatistics, Inselspital, University of Bern, CH 3010 Bern, Switzerland
    J Clin Endocrinol Metab 93:539-42. 2008
    ..The role of dehydroepiandrosterone-sulfate (DHEA-S) in assessing the integrity of the hypothalamic-pituitary-adrenal (HPA) axis in patients with suspected insufficiency is uncertain...
  8. ncbi request reprint Low-density lipoprotein apolipoprotein B100 turnover in hypopituitary patients with GH deficiency: a stable isotope study
    Emanuel R Christ
    Department of Endocrinology and Diabetology, University Hospital of Bern, Switzerland
    Eur J Endocrinol 154:459-66. 2006
    ..The underlying mechanisms are not fully elucidated...
  9. doi request reprint Effect of GH on human skeletal muscle lipid metabolism in GH deficiency
    Roman Trepp
    Division of Endocrinology, Diabetology and Clinical Nutrition, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland
    Am J Physiol Endocrinol Metab 294:E1127-34. 2008
    ..The upregulation of IGF-I mRNA suggests a paracrine/autocrine role of IGF-I on skeletal muscle...
  10. ncbi request reprint Exercise capacity in subjects with type 1 diabetes mellitus in eu- and hyperglycaemia
    Christoph Stettler
    Division of Endocrinology and Diabetes, University of Bern Inselspital, 3010 Bern, Switzerland
    Diabetes Metab Res Rev 22:300-6. 2006
    ..The aim of this study was to assess exercise capacity in eu- and hyperglycaemic conditions in subjects with type 1 diabetes...
  11. pmc The effect of aerobic exercise on intrahepatocellular and intramyocellular lipids in healthy subjects
    Andrea Egger
    Division of Endocrinology, Diabetology and Clinical Nutrition, University Hospital of Bern, Inselspital, Bern, Switzerland
    PLoS ONE 8:e70865. 2013
    ..The acute effect of aerobic exercise on IHCL is unknown. Possible regulatory factors include exercise capacity, insulin sensitivity and fat availability subcutaneous and visceral fat mass)...
  12. doi request reprint Long-term cardiovascular and non-cardiovascular mortality in women and men with type 1 and type 2 diabetes mellitus: a 30-year follow-up in Switzerland
    Sabin Allemann
    Division of Endocrinology, Diabetes and Clinical Nutrition, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland
    Swiss Med Wkly 139:576-83. 2009
    ..While studies from other countries have shown an excess mortality in diabetic individuals when compared with the general population, comparable long-term data is not available for Switzerland...
  13. pmc Effects of aerobic exercise on ectopic lipids in patients with growth hormone deficiency before and after growth hormone replacement therapy
    Emanuel R Christ
    Division of Endocrinology, Diabetology and Clinical Nutrition, University Hospital of Bern, Inselspital, CH 3010 Bern, Switzerland
    Sci Rep 6:19310. 2016
    ..GHRT didn't significantly impact on ∆IMCL and ∆IHCL. We conclude that aerobic exercise affects ectopic lipids in patients and controls. GHRT increases exercise capacity without influencing ectopic lipids...
  14. doi request reprint Assessment of three frequently used blood glucose monitoring devices in clinical routine
    Thomas Zueger
    Inselspital, Bern University Hospital, and University of Bern, Switzerland
    Swiss Med Wkly 142:w13631. 2012
    ..Direct comparison of different blood glucose meters in clinical practice, independent of the manufactures is scarce. We, therefore, aimed to evaluate three frequently used blood glucose meters in daily clinical practice...
  15. ncbi request reprint Effects of growth hormone (GH) replacement therapy on low-density lipoprotein apolipoprotein B100 kinetics in adult patients with GH deficiency: a stable isotope study
    E R Christ
    Department of Endocrinology and Diabetology, University Hospital of Bern, Bern CH 3100, Switzerland
    J Clin Endocrinol Metab 89:1801-7. 2004
    ..In addition, it is possible that the beneficial effects of GH on the cardiovascular system contribute to these findings...
  16. ncbi request reprint [Simultaneous defect of visual fields and loss of libido--a coincidence?]
    S Jenni
    Poliklinik für Endokrinologie, Diabetologie und Klinische Ernährung, Inselspital, Universitatsspital Bern
    Praxis (Bern 1994) 95:1925-30. 2006
    ..In contrast to other pituitary tumors that are mainly treated by surgery, medical treatment with dopamine agonists is the principal therapeutic option in prolactinomas...
  17. ncbi request reprint Growth hormone (GH) replacement therapy reduces serum sialic acid concentrations in adults with GH-deficiency: a double-blind placebo-controlled study
    E R Christ
    Department of Medicine, St Thomas Hospital UMDS, London, UK
    Clin Endocrinol (Oxf) 51:173-9. 1999
    ..SA as a marker of cardiovascular disease in adult GH-deficiency and its relation to changes in fasting lipid profile and hormone concentrations have not yet been investigated...
  18. ncbi request reprint Effects of alcohol consumption on mortality in patients with Type 2 diabetes mellitus
    P Diem
    Division of Endocrinology and Diabetes, University of Bern, Inselspital, Bern, Switzerland
    Diabetologia 46:1581-5. 2003
    ..We prospectively examined the effects of alcohol consumption on mortality in Type 2 diabetic patients in Switzerland...
  19. ncbi request reprint Apolipoprotein B as a long-term predictor of mortality in type 1 diabetes mellitus: a 15-year follow up
    C Stettler
    Division of Endocrinology and Diabetes, Department of Social and Preventive Medicine, University of Bern, Bern, Switzerland
    J Intern Med 260:272-80. 2006
    ..To evaluate the association of apolipoprotein B (apo B) with mortality due to all causes, to cardiac disease and to ischaemic heart disease (IHD) in subjects with type 1 diabetes mellitus...
  20. doi request reprint Exercise-induced GH secretion in the assessment of GH deficiency in adult individuals
    Thomas Zueger
    Division of Endocrinology, Diabetes and Clinical Nutrition, Inselspital, Bern University Hospital and University of Bern, CH 3010 Bern, Switzerland
    Eur J Endocrinol 165:723-8. 2011
    ..This study aimed at evaluating the diagnostic value of exercise-induced GH levels in the detection of severe GHD in adult patients...
  21. doi request reprint Peak oxygen uptake test in the assessment of growth hormone deficiency
    Thomas Zueger
    Division of Endocrinology, Diabetes and Clinical Nutrition, Inselspital, Bern University Hospital, and University of Bern, CH 3010 Bern, Switzerland
    Appl Physiol Nutr Metab 39:852-5. 2014
    ..A standardized peak oxygen uptake test may, therefore, provide an accurate alternative to more invasive tests of GHD. ..
  22. ncbi request reprint Fact or factitious?
    Stefan Jenni
    Division of Endocrinology, Diabetes, and Clinical Nutrition, University Hospital of Bern, Switzerland
    Am J Med 120:848-50. 2007
  23. ncbi request reprint QTc interval and resting heart rate as long-term predictors of mortality in type 1 and type 2 diabetes mellitus: a 23-year follow-up
    C Stettler
    Division of Endocrinology and Diabetes, University of Bern, Inselspital, CH 3010, Bern, Switzerland
    Diabetologia 50:186-94. 2007
    ..We evaluated the association of QT interval corrected for heart rate (QT(c)) and resting heart rate (rHR) with mortality (all-causes, cardiovascular, cardiac, and ischaemic heart disease) in subjects with type 1 and type 2 diabetes...
  24. pmc Changes of Thyroid Hormones and Their Binding Proteins during Plasma Exchange for Polyneuropathy in a Patient with Substituted Hypothyroidism due to Hashimoto's Thyroiditis
    Stefan Jenni
    Department of Endocrinology, Diabetology and Clinical Nutrition, Bern University Hospital, Inselspital, Bern, Switzerland
    Transfus Med Hemother 43:45-9. 2016
    ..Pharmacodynamic studies and data concerning adaptation of thyroid substitution in patients with substituted hypothyroidism during plasma exchange (PE) is not available...
  25. ncbi request reprint Assessment of quality of life in patients with uncontrolled vs. controlled acromegaly using the Acromegaly Quality of Life Questionnaire (AcroQoL)
    Roman Trepp
    Division of Endocrinology and Diabetes, University Hospital of Bern, Inselspital, Switzerland
    Clin Endocrinol (Oxf) 63:103-10. 2005
    ..We aimed to confirm reliability, construct validity and disease-specificity of the AcroQoL questionnaire. Second, we investigated the effect of remission status on health-related quality of life (HRQoL) in patients with acromegaly...
  26. ncbi request reprint Leiomyomatoid angiomatous neuroendocrine tumor (LANT) of the pituitary: a distinctive biphasic neoplasm with primitive secretory phenotype and smooth muscle-rich stroma
    Istvan Vajtai
    Institute of Pathology, University of Bern, Murtenstrasse 31, Postfach 62, 3010, Bern, Switzerland
    Acta Neuropathol 111:278-83. 2006
    ..While assignment of this lesion to any established neoplastic entity is not forthcoming, we propose it is being considered as a low-grade neuroendocrine tumor possibly related to null cell adenoma...
  27. ncbi request reprint Treatment outcomes and mortality of 94 patients with acromegaly
    R Trepp
    Division of Endocrinology and Diabetes, University Hospital of Bern, Inselspital, Bern, Switzerland
    Acta Neurochir (Wien) 147:243-51; discussion 250-1. 2005
    ..We analysed treatment outcomes and mortality of our patients with acromegaly seen between 1971 and 2003...
  28. ncbi request reprint Comparative effects of rosiglitazone and pioglitazone on fasting and postprandial low-density lipoprotein size and subclasses in patients with Type 2 diabetes
    Kaspar Berneis
    University Hospital Zurich, Clinics for Endocrinology, Diabetes and Clinical Nutrition, Switzerland
    Expert Opin Pharmacother 9:343-9. 2008
    ..To assess the effects of pioglitazone and rosiglitazone on fasting and postprandial low-density lipoprotein (LDL) size and subclasses in patients with Type 2 diabetes...
  29. ncbi request reprint Atherogenic lipoprotein phenotype and low-density lipoprotein size and subclasses in patients with growth hormone deficiency before and after short-term replacement therapy
    Manfredi Rizzo
    Department of Clinical Medicine and Emerging Diseases, University of Palermo, Palermo, Italy
    Eur J Endocrinol 156:361-7. 2007
    ....
  30. ncbi request reprint Clinicopathologic correlations of silent corticotroph adenomas of the pituitary: report of four cases and literature review
    Rahel Sahli
    Department of Endocrinology, University Hospital Berne, Berne, Switzerland
    Pathol Res Pract 202:457-64. 2006
    ..Subtle morphologic evidence of corticotroph suppression in residual pituitary adjacent to tumor lends further support to literature data indicating minimal or intermittent functional activity in this tumor type...
  31. ncbi request reprint Post-prandial alterations in LDL size and subclasses in patients with growth hormone deficiency
    Manfredi Rizzo
    Department of Clinical Medicine and Emerging Diseases, University of Palermo, Italy
    Growth Horm IGF Res 18:264-6. 2008
    ..In the present study we assessed post-prandial variations in LDL size and subclasses in patients with growth hormone deficiency (GHD)...
  32. ncbi request reprint The differential effects of thiazolidindiones on atherogenic dyslipidemia in type 2 diabetes: what is the clinical significance?
    Manfredi Rizzo
    University of Palermo, Department of Internal Medicine and Emerging Diseases, Via del Vespro 141, 90127 Palermo, Italy
    Expert Opin Pharmacother 9:2295-303. 2008
    ....